The ubiquitin ligase parkin mediates resistance to intracellular pathogens

Antimicrobial Autophagy: A Conserved Innate Immune Response inDrosophila

(2013) Ryan H. Moy et al.   Journal of Innate Immunity

Mapping of PARK2 and PACRG Overlapping Regulatory Region Reveals LD Structure and Functional Variants in Association with Leprosy in Unrelated Indian Population Groups

(2013) Rupali Chopra et al.   PLoS Genetics

PARK2 Mediates Interleukin 6 and Monocyte Chemoattractant Protein 1 Production by Human Macrophages

(2013) Louis de Léséleuc et al.   PLoS Neglected Tropical Diseases

ESX-1 dependent impairment of autophagic flux byMycobacterium tuberculosisin human dendritic cells

(2012) Alessandra Romagnoli et al.   Autophagy

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

(2012) Robert O. Watson et al.   CELL

The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin-Dependent Autophagy of Intracellular Salmonella Typhimurium

(2012) Alan Huett et al.   Cell Host & Microbe

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

(2012) Diane Houben et al.   CELLULAR MICROBIOLOGY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax

(2012) B. N. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy regulates Wolbachia populations across diverse symbiotic associations

(2012) D. Voronin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent Advances in the Genetics of Parkinson's Disease

(2011) Ian Martin et al.   Annual Review of Genomics and Human Genetics

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

(2011) Kye-Young Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Listeria monocytogenestransiently alters mitochondrial dynamics during infection

(2011) Fabrizia Stavru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

(2010) Derek Narendra et al.   Autophagy

Mycobacterium tuberculosis MycP1 Protease Plays a Dual Role in Regulation of ESX-1 Secretion and Virulence

(2010) Yamini M. Ohol et al.   Cell Host & Microbe

Delivery of Cytosolic Components by Autophagic Adaptor Protein p62 Endows Autophagosomes with Unique Antimicrobial Properties

(2010) Marisa Ponpuak et al.   IMMUNITY

Parkin Mono-ubiquitinates Bcl-2 and Regulates Autophagy

(2010) Dong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy, Immunity, and Microbial Adaptations

(2009) Vojo Deretic et al.   Cell Host & Microbe

Atg5-Independent Sequestration of Ubiquitinated Mycobacteria

(2009) Cathleen A. Collins et al.   PLoS Pathogens

Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies

(2008) Kim Newton et al.   CELL

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

Autophagic control of listeria through intracellular innate immune recognition in drosophila

(2008) Tamaki Yano et al.   NATURE IMMUNOLOGY

A Signaling Protease Required for Melanization in Drosophila Affects Resistance and Tolerance of Infections

(2008) Janelle S Ayres et al.   PLOS BIOLOGY