Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism
出版年份 2017 全文链接
标题
Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism
作者
关键词
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出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 114, Issue 4, Pages 746-751
出版商
Proceedings of the National Academy of Sciences
发表日期
2017-01-10
DOI
10.1073/pnas.1611113114
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- S6K-STING interaction regulates cytosolic DNA–mediated activation of the transcription factor IRF3
- (2016) Fuan Wang et al. NATURE IMMUNOLOGY
- STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease
- (2015) Nicole Dobbs et al. Cell Host & Microbe
- Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation
- (2015) Maroof Hasan et al. IMMUNITY
- Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice
- (2015) Maroof Hasan et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi–Goutières Syndrome
- (2015) Elizabeth E. Gray et al. JOURNAL OF IMMUNOLOGY
- Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
- (2015) Daxing Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation
- (2015) Jiayi Yu et al. Nature Communications
- TBK1 Regulates Prostate Cancer Dormancy through mTOR Inhibition
- (2015) Jin Koo Kim et al. NEOPLASIA
- Liver Damage, Inflammation, and Enhanced Tumorigenesis after Persistent mTORC1 Inhibition
- (2014) Atsushi Umemura et al. Cell Metabolism
- Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling
- (2014) Z. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling
- (2013) Hiroyasu Konno et al. CELL
- SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature
- (2013) Amy M. Becker et al. PLoS One
- Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
- (2012) Alevtina Gall et al. IMMUNITY
- The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue
- (2012) Maria J. Pereira et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes
- (2012) Maroof Hasan et al. NATURE IMMUNOLOGY
- Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity
- (2011) Huihui Chen et al. CELL
- TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation
- (2011) Yi-Hung Ou et al. MOLECULAR CELL
- Pyruvate carboxylase is required for glutamine-independent growth of tumor cells
- (2011) T. Cheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
- (2010) Katrin Düvel et al. MOLECULAR CELL
- Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity
- (2009) Y. J. Crow et al. HUMAN MOLECULAR GENETICS
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
- (2008) Daniel B. Stetson et al. CELL
- Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration
- (2008) Pazit Polak et al. Cell Metabolism
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