标题
Metabolism-Based Therapeutic Strategies Targeting Cancer Stem Cells
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-03-22
DOI
10.3389/fphar.2019.00203
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Ketogenic diet in cancer therapy
- (2018) Daniela D. Weber et al. Aging-US
- Lipid metabolism and lipophagy in cancer
- (2018) Meenu Maan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cancer stem cells (CSCs): metabolic strategies for their identification and eradication
- (2018) Ernestina M. De Francesco et al. BIOCHEMICAL JOURNAL
- Bergamot natural products eradicate cancer stem cells (CSCs) by targeting mevalonate, Rho-GDI-signalling and mitochondrial metabolism
- (2018) Marco Fiorillo et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling
- (2018) Ming Luo et al. Cell Metabolism
- JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance
- (2018) Tianyi Wang et al. Cell Metabolism
- Graphene Oxide–Silver Nanocomposite Enhances Cytotoxic and Apoptotic Potential of Salinomycin in Human Ovarian Cancer Stem Cells (OvCSCs): A Novel Approach for Cancer Therapy
- (2018) Yun-Jung Choi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I
- (2018) Lucas Robke et al. Chemical Science
- ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells
- (2018) Ching-Wen Chang et al. Cell Death & Disease
- Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors
- (2018) Sergey Malchenko et al. Oncotarget
- Mitochondrial fission as a driver of stemness in tumor cells: mDIVI1 inhibits mitochondrial function, cell migration and cancer stem cell (CSC) signalling
- (2018) Maria Peiris-Pagès et al. Oncotarget
- Effects of metformin on colorectal cancer stem cells depend on alterations in glutamine metabolism
- (2018) Jae Hyun Kim et al. Scientific Reports
- Regulation of Cancer Stem Cell Metabolism by Secreted Frizzled-Related Protein 4 (sFRP4)
- (2018) Abhijeet Deshmukh et al. Cancers
- Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways
- (2018) Runjie Wei et al. CELL STRESS & CHAPERONES
- Metabolomic Alterations in Thyrospheres and Adherent Parental Cells in Papillary Thyroid Carcinoma Cell Lines: A Pilot Study
- (2018) Paola Caria et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase (ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling
- (2018) Donghyeok Kim et al. Cell Death & Disease
- Phosphoglycerate dehydrogenase inhibition induces p-mTOR-independent autophagy and promotes multilineage differentiation in embryonal carcinoma stem-like cells
- (2018) Tanveer Sharif et al. Cell Death & Disease
- Mitochondrial Complex I Activity Is Required for Maximal Autophagy
- (2018) Hala Elnakat Thomas et al. Cell Reports
- Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma
- (2018) Jiale Wang et al. CANCER BIOLOGY & THERAPY
- Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells
- (2018) Courtney L. Jones et al. CANCER CELL
- L‑Deprenyl exerts cytotoxicity towards acute myeloid leukemia through inhibition of mitochondrial respiration
- (2018) Ilhwan Ryu et al. ONCOLOGY REPORTS
- Ovarian cancer cell-derived lysophosphatidic acid induces glycolytic shift and cancer-associated fibroblast-phenotype in normal and peritumoral fibroblasts
- (2018) Rangasudhagar Radhakrishnan et al. CANCER LETTERS
- Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6
- (2017) Keane K.Y. Lai et al. GASTROENTEROLOGY
- Lipid Storage and Autophagy in Melanoma Cancer Cells
- (2017) Claudia Giampietri et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- 188Re-Liposome Can Induce Mitochondrial Autophagy and Reverse Drug Resistance for Ovarian Cancer: From Bench Evidence to Preliminary Clinical Proof-of-Concept
- (2017) Chia-Ming Chang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- ROS-modulated therapeutic approaches in cancer treatment
- (2017) Muhammad Hassan Raza et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer
- (2017) Daniela Massihnia et al. Journal of Hematology & Oncology
- Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation
- (2017) Mark Kin Fai Ma et al. JOURNAL OF HEPATOLOGY
- Proteomic analysis of pancreatic cancer stem cells: Functional role of fatty acid synthesis and mevalonate pathways
- (2017) Jessica Brandi et al. Journal of Proteomics
- Regulation of stem-like cancer cells by glutamine through β-catenin pathway mediated by redox signaling
- (2017) Jianwei Liao et al. Molecular Cancer
- Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation
- (2017) Jonathan B. Bell et al. MOLECULAR CANCER RESEARCH
- Triphenyl Phosphine-Functionalized Chitosan Nanoparticles Enhanced Antitumor Efficiency Through Targeted Delivery of Doxorubicin to Mitochondria
- (2017) Jiahui Hou et al. Nanoscale Research Letters
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
- (2017) Xiuxing Wang et al. NATURE NEUROSCIENCE
- Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres
- (2017) Junseong Park et al. NEURO-ONCOLOGY
- Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance
- (2017) K A Whelan et al. ONCOGENE
- Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ
- (2017) A Noto et al. ONCOGENE
- Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model
- (2017) Ji Ho Yun et al. PHYTOMEDICINE
- Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer
- (2017) Pasquale Sansone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Guanylate-binding protein 2 regulates Drp1-mediated mitochondrial fission to suppress breast cancer cell invasion
- (2017) Juan Zhang et al. Cell Death & Disease
- Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2
- (2017) Bing Xu et al. Cell Death & Disease
- CD44+CD24+ subset of PANC-1 cells exhibits radiation resistance via decreased levels of reactive oxygen species
- (2017) Lei Wang et al. Oncology Letters
- Mitoketoscins: Novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs)
- (2017) Bela Ozsvari et al. Oncotarget
- Targeting hypoxic cancer stem cells (CSCs) with Doxycycline: Implications for optimizing anti-angiogenic therapy
- (2017) Ernestina Marianna De Francesco et al. Oncotarget
- Lovastatin Inhibits Cancer Stem Cells and Sensitizes to Chemo- and Photodynamic Therapy in Nasopharyngeal Carcinoma
- (2017) Yikun Peng et al. Journal of Cancer
- Molecular Subtyping of Pancreatic Cancer: Translating Genomics and Transcriptomics into the Clinic
- (2017) Yongxing Du et al. Journal of Cancer
- Triphenyl Phosphine-Functionalized Chitosan Nanoparticles Enhanced Antitumor Efficiency Through Targeted Delivery of Doxorubicin to Mitochondria
- (2017) Jiahui Hou et al. Nanoscale Research Letters
- Identification of a New Potent Inhibitor Targeting KRAS in Non-small Cell Lung Cancer Cells
- (2017) Chun Xie et al. Frontiers in Pharmacology
- Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis
- (2017) Jong-Lyel Roh et al. Redox Biology
- Controversy about pharmacological modulation of Nrf2 for cancer therapy
- (2017) Lidija Milkovic et al. Redox Biology
- Effect of Selumetinib and MK-2206 vs Oxaliplatin and Fluorouracil in Patients With Metastatic Pancreatic Cancer After Prior Therapy
- (2017) Vincent Chung et al. JAMA Oncology
- Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis
- (2017) Chiara Giacomelli et al. Scientific Reports
- Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)
- (2016) Marco Fiorillo et al. Aging-US
- Hallmarks of cancer stem cell metabolism
- (2016) Patricia Sancho et al. BRITISH JOURNAL OF CANCER
- Gemcitabine treatment promotes pancreatic cancer stemness through the Nox/ROS/NF-κB/STAT3 signaling cascade
- (2016) Zhengle Zhang et al. CANCER LETTERS
- PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis
- (2016) D. Samanta et al. CANCER RESEARCH
- Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis
- (2016) J. A. Menard et al. CANCER RESEARCH
- Metabolic Heterogeneity in Human Lung Tumors
- (2016) Christopher T. Hensley et al. CELL
- NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism
- (2016) Chia-Lin Chen et al. Cell Metabolism
- Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche
- (2016) Haobin Ye et al. Cell Stem Cell
- Activation of NRF2 Signaling in Breast Cancer Stem Cell-Enriched Population
- (2016) Mi-Kyoung Kwak et al. FREE RADICAL BIOLOGY AND MEDICINE
- Hyaluronan Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling
- (2016) Theerawut Chanmee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer metabolism at a glance
- (2016) Alexei Vazquez et al. JOURNAL OF CELL SCIENCE
- Mitochondria and Cancer
- (2016) Wei-Xing Zong et al. MOLECULAR CELL
- Stable loading and delivery of disulfiram with mPEG-PLGA/PCL mixed nanoparticles for tumor therapy
- (2016) Wantong Song et al. Nanomedicine-Nanotechnology Biology and Medicine
- Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
- (2016) Cristovão M. Sousa et al. NATURE
- Targeting metastasis-initiating cells through the fatty acid receptor CD36
- (2016) Gloria Pascual et al. NATURE
- A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
- (2016) Chi Luo et al. NATURE
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
- (2016) Roman Camarda et al. NATURE MEDICINE
- NRF2, a Key Regulator of Antioxidants with Two Faces towards Cancer
- (2016) Jaieun Kim et al. Oxidative Medicine and Cellular Longevity
- Reactive Oxygen Species Regulate T Cell Immune Response in the Tumor Microenvironment
- (2016) Xinfeng Chen et al. Oxidative Medicine and Cellular Longevity
- Redox Modulating NRF2: A Potential Mediator of Cancer Stem Cell Resistance
- (2016) In-geun Ryoo et al. Oxidative Medicine and Cellular Longevity
- Increased Expression of the Glucose Transporter Type 1 Gene Is Associated With Worse Overall Survival in Resected Pancreatic Adenocarcinoma
- (2016) Ashley H. Davis-Yadley et al. PANCREAS
- Apigenin Inhibits Cancer Stem Cell-Like Phenotypes in Human Glioblastoma Cells via Suppression of c-Met Signaling
- (2016) Boram Kim et al. PHYTOTHERAPY RESEARCH
- Enhancement of Radiation Response in Breast Cancer Stem Cells by Inhibition of Thioredoxin- and Glutathione-Dependent Metabolism
- (2016) Samuel N. Rodman et al. RADIATION RESEARCH
- Autotaxin Regulates Maintenance of Ovarian Cancer Stem Cells through Lysophosphatidic Acid-Mediated Autocrine Mechanism
- (2016) Eun Jin Seo et al. STEM CELLS
- Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program
- (2016) Esther Aguilar et al. STEM CELLS
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Mitochondrial Permeability Transition: New Findings and Persisting Uncertainties
- (2016) Valentina Izzo et al. TRENDS IN CELL BIOLOGY
- Self-renewal of CD133hi cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer
- (2016) Pasquale Sansone et al. Nature Communications
- Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival
- (2016) Edoardo Gaude et al. Nature Communications
- Polycomb complex protein BMI-1 promotes invasion and metastasis of pancreatic cancer stem cells by activating PI3K/AKT signaling, an ex vivo, in vitro, and in vivo study
- (2016) Min-Cong Wang et al. Oncotarget
- Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma
- (2016) Tiziana Petrachi et al. Oncotarget
- Targeting ALDH1A1 by disulfiram/copper complex inhibits non-small cell lung cancer recurrence driven by ALDH-positive cancer stem cells
- (2016) Xinwei Liu et al. Oncotarget
- Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism
- (2016) Bisrat G. Debeb et al. Oncotarget
- NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells
- (2016) Clarissa Ribeiro Reily Rocha et al. Oncotarget
- Mitochondrial dysfunction and oxidative stress in aging and cancer
- (2016) Anna V. Kudryavtseva et al. Oncotarget
- Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle
- (2016) Masakazu Sato et al. Oncotarget
- Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions
- (2016) Geou-Yarh Liou et al. Cell Reports
- NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming
- (2016) Kate E. Hawkins et al. Cell Reports
- Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
- (2016) Hongyun Zhao et al. eLife
- Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells
- (2016) Genki Tanaka et al. Cancer Medicine
- Lipid metabolic reprogramming in cancer cells
- (2016) S Beloribi-Djefaflia et al. Oncogenesis
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- Inhibition of Fatty Acid Synthase Decreases Expression of Stemness Markers in Glioma Stem Cells
- (2016) Yuki Yasumoto et al. PLoS One
- A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission
- (2015) Jing Zhou et al. Autophagy
- Cancer associated fibroblasts transfer lipids and proteins to cancer cells through cargo vesicles supporting tumor growth
- (2015) Alice Santi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Targeting the leukemia cell metabolism by the CPT1a inhibition: functional preclinical effects in leukemias
- (2015) M. R. Ricciardi et al. BLOOD
- Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
- (2015) Isaac S. Harris et al. CANCER CELL
- Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death
- (2015) E. A. Lee et al. CANCER RESEARCH
- Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
- (2015) J. J. Kamphorst et al. CANCER RESEARCH
- MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells
- (2015) Patricia Sancho et al. Cell Metabolism
- TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells
- (2015) ZhengMing Wu et al. Cell Stem Cell
- Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate
- (2015) P. Korangath et al. CLINICAL CANCER RESEARCH
- (Ir)relevance of Metformin Treatment in Patients with Metastatic Pancreatic Cancer: An Open-Label, Randomized Phase II Trial
- (2015) M. Reni et al. CLINICAL CANCER RESEARCH
- Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
- (2015) A. H. Chourasia et al. EMBO REPORTS
- Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice
- (2015) Dingzhi Wang et al. GASTROENTEROLOGY
- Mitochondria: The ketogenic diet—A metabolism-based therapy
- (2015) Silvia Vidali et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF V600E Melanoma
- (2015) Shira Y. Wieder et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial
- (2015) Sil Kordes et al. LANCET ONCOLOGY
- The c-Myc–LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer
- (2015) Tian-Lin He et al. MEDICAL ONCOLOGY
- Erk2 Phosphorylation of Drp1 Promotes Mitochondrial Fission and MAPK-Driven Tumor Growth
- (2015) Jennifer A. Kashatus et al. MOLECULAR CELL
- Oxidative stress inhibits distant metastasis by human melanoma cells
- (2015) Elena Piskounova et al. NATURE
- Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
- (2015) Pawel K Mazur et al. NATURE MEDICINE
- Mitochondrial control by DRP1 in brain tumor initiating cells
- (2015) Qi Xie et al. NATURE NEUROSCIENCE
- 1H NMR spectroscopy of glioblastoma stem-like cells identifies alpha-aminoadipate as a marker of tumor aggressiveness
- (2015) Antonella Rosi et al. NMR IN BIOMEDICINE
- Regulation of mammalian nucleotide metabolism and biosynthesis
- (2015) Andrew N. Lane et al. NUCLEIC ACIDS RESEARCH
- SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme
- (2015) C A Lewis et al. ONCOGENE
- The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models
- (2015) P L Garcia et al. ONCOGENE
- Oxidative Stress Responses and NRF2 in Human Leukaemia
- (2015) Amina Abdul-Aziz et al. Oxidative Medicine and Cellular Longevity
- Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405
- (2015) Brandon L. Probst et al. PLoS One
- Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma
- (2015) Fabienne Guillaumond et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
- (2015) M. Cecilia Caino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Suppression of cancer relapse and metastasis by inhibiting cancer stemness
- (2015) Youzhi Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness
- (2015) P. Katajisto et al. SCIENCE
- Concise Review: Stem Cells in Pancreatic Cancer: From Concept to Translation
- (2015) Deepak Raj et al. STEM CELLS
- Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells
- (2015) Jie Cheng et al. Nature Communications
- Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy
- (2015) Rebecca Lamb et al. Oncotarget
- Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling
- (2015) Rebecca Lamb et al. Oncotarget
- Active glycolytic metabolism in CD133(+) hepatocellular cancer stem cells: regulation by MIR-122
- (2015) Kyoungsub Song et al. Oncotarget
- Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy
- (2015) Doudou Li et al. Oncotarget
- Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease
- (2015) Rebecca Lamb et al. Oncotarget
- Disulfiram anti-cancer efficacy without copper overload is enhanced by extracellular H2O2 generation: antagonism by tetrathiomolybdate
- (2015) Ali Calderon-Aparicio et al. Oncotarget
- Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells
- (2015) Arianna De Luca et al. Oncotarget
- Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism
- (2015) Shuqiang Yuan et al. Stem Cell Research & Therapy
- Doxycycline Induces Apoptosis and Inhibits Proliferation and Invasion of Human Cervical Carcinoma Stem Cells
- (2015) Binlie Yang et al. PLoS One
- RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity
- (2015) Brandon L. Probst et al. PLoS One
- Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation
- (2015) Anna Pastò et al. Oncotarget
- Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells
- (2015) Bruna Corominas-Faja et al. Oncotarget
- The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells
- (2014) Michaël Boyer-Guittaut et al. Autophagy
- Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity
- (2014) Peng Sun et al. BMC CANCER
- Omega-3 Fatty Acid Is a Potential Preventive Agent for Recurrent Colon Cancer
- (2014) A. Vasudevan et al. Cancer Prevention Research
- Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma
- (2014) Yao-An Shen et al. CELL CYCLE
- Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells
- (2014) I Vega-Naredo et al. CELL DEATH AND DIFFERENTIATION
- Blocking Lipid Synthesis Overcomes Tumor Regrowth and Metastasis after Antiangiogenic Therapy Withdrawal
- (2014) Nor Eddine Sounni et al. Cell Metabolism
- Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness
- (2014) Shuhua Yue et al. Cell Metabolism
- Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling
- (2014) Manash K. Paul et al. Cell Stem Cell
- Stem cells and the impact of ROS signaling
- (2014) C. L. Bigarella et al. DEVELOPMENT
- A randomised, double-blind, placebo-controlled trial of trametinib, an oral MEK inhibitor, in combination with gemcitabine for patients with untreated metastatic adenocarcinoma of the pancreas
- (2014) Jeffrey R. Infante et al. EUROPEAN JOURNAL OF CANCER
- Ovarian tumor-initiating cells display a flexible metabolism
- (2014) Angela S. Anderson et al. EXPERIMENTAL CELL RESEARCH
- Excessive Hyaluronan Production Promotes Acquisition of Cancer Stem Cell Signatures through the Coordinated Regulation of Twist and the Transforming Growth Factor β (TGF-β)-Snail Signaling Axis
- (2014) Theerawut Chanmee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations
- (2014) Francesca Mateo et al. Molecular Cancer
- Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy?
- (2014) Tongde Wu et al. MOLECULAR CARCINOGENESIS
- Mitochondrial Delivery of Doxorubicin via Triphenylphosphine Modification for Overcoming Drug Resistance in MDA-MB-435/DOX Cells
- (2014) Min Han et al. MOLECULAR PHARMACEUTICS
- Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
- (2014) Antonina V. Kurtova et al. NATURE
- Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
- (2014) Andrea Viale et al. NATURE
- Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism
- (2014) Jianqun Liao et al. PLoS One
- Cancer Cells Differentially Activate and Thrive on De Novo Lipid Synthesis Pathways in a Low-Lipid Environment
- (2014) Veerle W. Daniëls et al. PLoS One
- Detouring of cisplatin to access mitochondrial genome for overcoming resistance
- (2014) S. Marrache et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor Microenvironment: Introduction
- (2014) Ubaldo E. Martinez-Outschoorn et al. SEMINARS IN ONCOLOGY
- Cancer Stem Cell-Specific Scavenger Receptor CD36 Drives Glioblastoma Progression
- (2014) James S. Hale et al. STEM CELLS
- Lipid Droplets: A New Player in Colorectal Cancer Stem Cells Unveiled by Spectroscopic Imaging
- (2014) Luca Tirinato et al. STEM CELLS
- Inhibition of the Cancer Stem Cells-Like Properties by Arsenic Trioxide, Involved in the Attenuation of Endogenous Transforming Growth Factor Beta Signal
- (2014) Yuan Li et al. TOXICOLOGICAL SCIENCES
- Metabolism addiction in pancreatic cancer
- (2014) R Blum et al. Cell Death & Disease
- Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment
- (2014) D Ciavardelli et al. Cell Death & Disease
- Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments
- (2014) Xiaonan Zhang et al. Nature Communications
- Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation
- (2014) Naoya Hirata et al. Nature Communications
- A High-Throughput Fluorimetric Assay for 2-Hydroxyglutarate Identifies Zaprinast as a Glutaminase Inhibitor
- (2014) A. Elhammali et al. Cancer Discovery
- A Mitochondrial Switch Promotes Tumor Metastasis
- (2014) Paolo E. Porporato et al. Cell Reports
- MYC Activation Is a Hallmark of Cancer Initiation and Maintenance
- (2014) M. Gabay et al. Cold Spring Harbor Perspectives in Medicine
- Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
- (2014) William W Wheaton et al. eLife
- Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres
- (2014) Dacheng Ding et al. Acta Neuropathologica Communications
- Targeted Delivery of Doxorubicin to Mitochondria
- (2013) Graham R. Chamberlain et al. ACS Chemical Biology
- Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells
- (2013) Annegret Kathagen et al. ACTA NEUROPATHOLOGICA
- Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: Differences between primary and cancer cells
- (2013) Jaganmohan Reddy Jangamreddy et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Nrf2 is required to maintain the self-renewal of glioma stem cells
- (2013) Jianhong Zhu et al. BMC CANCER
- Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death
- (2013) Gang Cheng et al. BMC CANCER
- Disulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells
- (2013) P Liu et al. BRITISH JOURNAL OF CANCER
- Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
- (2013) Rizwan Haq et al. CANCER CELL
- Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
- (2013) Chenfang Dong et al. CANCER CELL
- Differential sensitivities of glioblastoma cell lines towards metabolic and signaling pathway inhibitions
- (2013) Colin R. Kennedy et al. CANCER LETTERS
- Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer
- (2013) W.-c. Lin et al. CANCER RESEARCH
- Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
- (2013) J. R. Doherty et al. CANCER RESEARCH
- Adipocytes Cause Leukemia Cell Resistance to L-Asparaginase via Release of Glutamine
- (2013) E. A. Ehsanipour et al. CANCER RESEARCH
- Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway
- (2013) P-P Liu et al. CELL DEATH AND DIFFERENTIATION
- The Mitochondrial Chaperone TRAP1 Promotes Neoplastic Growth by Inhibiting Succinate Dehydrogenase
- (2013) Marco Sciacovelli et al. Cell Metabolism
- BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
- (2013) Eleni D. Lagadinou et al. Cell Stem Cell
- Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis
- (2013) Y. Touil et al. CLINICAL CANCER RESEARCH
- FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells
- (2013) Hyeonju Yeo et al. EMBO JOURNAL
- A Preclinical Evaluation of Antimycin A as a Potential Antilung Cancer Stem Cell Agent
- (2013) Chi-Tai Yeh et al. Evidence-based Complementary and Alternative Medicine
- Resveratrol Impedes the Stemness, Epithelial-Mesenchymal Transition, and Metabolic Reprogramming of Cancer Stem Cells in Nasopharyngeal Carcinoma through p53 Activation
- (2013) Yao-An Shen et al. Evidence-based Complementary and Alternative Medicine
- MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer
- (2013) Hongping Xia et al. HEPATOLOGY
- Anti-Tumor Effects of Mfn2 in Gastric Cancer
- (2013) Ge-Er Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Energy Metabolism Characterization of a Novel Cancer Stem Cell-Like Line 3AB-OS
- (2013) Roberta Palorini et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia
- (2013) J. Fan et al. Molecular Systems Biology
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- Mitochondrial retrograde signaling induces epithelial–mesenchymal transition and generates breast cancer stem cells
- (2013) M Guha et al. ONCOGENE
- The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics
- (2013) R Kang et al. ONCOGENE
- Sub-Sets of Cancer Stem Cells Differ Intrinsically in Their Patterns of Oxygen Metabolism
- (2013) Luke Gammon et al. PLoS One
- Drug Screening Identifies Niclosamide as an Inhibitor of Breast Cancer Stem-Like Cells
- (2013) Yu-Chi Wang et al. PLoS One
- Omega-3 Eicosapentaenoic Acid Decreases CD133 Colon Cancer Stem-Like Cell Marker Expression While Increasing Sensitivity to Chemotherapy
- (2013) Flavia De Carlo et al. PLoS One
- Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells
- (2013) Y.-J. Liang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
- (2013) J. J. Kamphorst et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging targets in pancreatic cancer: epithelial–mesenchymal transition and cancer stem cells
- (2013) Nagaraj Nagathihalli et al. OncoTargets and Therapy
- Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells
- (2013) A Noto et al. Cell Death & Disease
- Glucose availability is a decisive factor for Nrf2-mediated gene expression
- (2013) Elke H. Heiss et al. Redox Biology
- Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s
- (2012) Young Chan Chae et al. CANCER CELL
- Metabolic Signatures Uncover Distinct Targets in Molecular Subsets of Diffuse Large B Cell Lymphoma
- (2012) Pilar Caro et al. CANCER CELL
- Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
- (2012) Yoichiro Mitsuishi et al. CANCER CELL
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
- (2012) Haoqiang Ying et al. CELL
- EMT and Dissemination Precede Pancreatic Tumor Formation
- (2012) Andrew D. Rhim et al. CELL
- Induction of cancer cell stemness by chemotherapy
- (2012) Xingwang Hu et al. CELL CYCLE
- c-Myc and Cancer Metabolism
- (2012) D. M. Miller et al. CLINICAL CANCER RESEARCH
- Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer
- (2012) Jalees Rehman et al. FASEB JOURNAL
- Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
- (2012) M. Janiszewska et al. GENES & DEVELOPMENT
- Hyaluronan-CD44v3 Interaction with Oct4-Sox2-Nanog Promotes miR-302 Expression Leading to Self-renewal, Clonal Formation, and Cisplatin Resistance in Cancer Stem Cells from Head and Neck Squamous Cell Carcinoma
- (2012) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Salinomycin as a Drug for Targeting Human Cancer Stem Cells
- (2012) Cord Naujokat et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis
- (2012) Venkata Lokesh Battula et al. JOURNAL OF CLINICAL INVESTIGATION
- A metabolic prosurvival role for PML in breast cancer
- (2012) Arkaitz Carracedo et al. JOURNAL OF CLINICAL INVESTIGATION
- Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo
- (2012) Swati Biswas et al. JOURNAL OF CONTROLLED RELEASE
- N-3 PUFAs have antiproliferative and apoptotic effects on human colorectal cancer stem-like cells in vitro
- (2012) Ting Yang et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Growth Inhibition of Ovarian Tumor-Initiating Cells by Niclosamide
- (2012) Y.-T. Yo et al. MOLECULAR CANCER THERAPEUTICS
- Regulation of pancreatic cancer growth by superoxide
- (2012) Juan Du et al. MOLECULAR CARCINOGENESIS
- A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
- (2012) Keisuke Ito et al. NATURE MEDICINE
- Elevated lipogenesis in epithelial stem-like cell confers survival advantage in ductal carcinoma in situ of breast cancer
- (2012) P R Pandey et al. ONCOGENE
- Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity
- (2012) A Arlt et al. ONCOGENE
- Mitochondrial dynamics regulates migration and invasion of breast cancer cells
- (2012) J Zhao et al. ONCOGENE
- Alterations in Glutathione Levels and Apoptotic Regulators Are Associated with Acquisition of Arsenic Trioxide Resistance in Multiple Myeloma
- (2012) Shannon M. Matulis et al. PLoS One
- Effective Elimination of Cancer Stem Cells By a Novel Drug Combination Strategy
- (2012) Shuqiang Yuan et al. STEM CELLS
- Mevalonate Metabolism Regulates Basal Breast Cancer Stem Cells and Is a Potential Therapeutic Target
- (2012) Christophe Ginestier et al. STEM CELLS
- Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells
- (2011) T. Yahata et al. BLOOD
- 12-prostaglandin J3, an omega-3 fatty acid-derived metabolite, selectively ablates leukemia stem cells in mice
- (2011) S. Hegde et al. BLOOD
- Disulfiram modulated ROS–MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties
- (2011) N C Yip et al. BRITISH JOURNAL OF CANCER
- Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia
- (2011) Marko Škrtić et al. CANCER CELL
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis
- (2011) Myriam Labelle et al. CANCER CELL
- Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types
- (2011) D. Iliopoulos et al. CANCER RESEARCH
- Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression
- (2011) B. Bao et al. CANCER RESEARCH
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway
- (2011) L Qiang et al. CELL DEATH AND DIFFERENTIATION
- High-Mobility Group Box 1 Is Essential for Mitochondrial Quality Control
- (2011) Daolin Tang et al. Cell Metabolism
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner
- (2011) Janel E. Le Belle et al. Cell Stem Cell
- Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment
- (2011) Yanique I. Rattigan et al. EXPERIMENTAL CELL RESEARCH
- Lipid rafts: signaling and sorting platforms of cells and their roles in cancer
- (2011) Simon Staubach et al. Expert Review of Proteomics
- Mitochondrial and energy metabolism-related properties as novel indicators of lung cancer stem cells
- (2011) Xiao-Qun Ye et al. INTERNATIONAL JOURNAL OF CANCER
- LY294002 and Metformin Cooperatively Enhance the Inhibition of Growth and the Induction of Apoptosis of Ovarian Cancer Cells
- (2011) Cuilan Li et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Metabolic Alterations in Highly Tumorigenic Glioblastoma Cells
- (2011) Yunfei Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of reactive oxygen species in stem cells and cancer stem cells
- (2011) Chiharu I. Kobayashi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth
- (2011) D. Gaglio et al. Molecular Systems Biology
- Reductive carboxylation supports growth in tumour cells with defective mitochondria
- (2011) Andrew R. Mullen et al. NATURE
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival
- (2011) V Goidts et al. ONCOGENE
- Transient Alteration of Cellular Redox Buffering before Irradiation Triggers Apoptosis in Head and Neck Carcinoma Stem and Non-Stem Cells
- (2011) Anthony Boivin et al. PLoS One
- Acidic Environment Leads to ROS-Induced MAPK Signaling in Cancer Cells
- (2011) Anne Riemann et al. PLoS One
- Asymmetric cancer cell division regulated by AKT
- (2011) I. Dey-Guha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anticancer Targets in the Glycolytic Metabolism of Tumors: A Comprehensive Review
- (2011) Paolo E. Porporato et al. Frontiers in Pharmacology
- Choosing between glycolysis and oxidative phosphorylation: A tumor's dilemma?
- (2010) Caroline Jose et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
- (2010) Jian-Bin Wang et al. CANCER CELL
- De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
- (2010) E. Rysman et al. CANCER RESEARCH
- Synergistic Activity of Sorafenib and Sulforaphane Abolishes Pancreatic Cancer Stem Cell Characteristics
- (2010) Vanessa Rausch et al. CANCER RESEARCH
- Ketones and lactate “fuel” tumor growth and metastasis
- (2010) Gloria Bonuccelli et al. CELL CYCLE
- Metformin regulates breast cancer stem cello ntogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status
- (2010) Alejandro Vazquez-Martin et al. CELL CYCLE
- The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
- (2010) Tugba Simsek et al. Cell Stem Cell
- Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
- (2010) Keiyo Takubo et al. Cell Stem Cell
- Reactive oxygen species in cancer
- (2010) Geou-Yarh Liou et al. FREE RADICAL RESEARCH
- Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells
- (2010) Katarína Smolková et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Glutamine targeting inhibits systemic metastasis in the VM-M3 murine tumor model
- (2010) Laura M. Shelton et al. INTERNATIONAL JOURNAL OF CANCER
- Gemcitabine plus sorafenib in patients with advanced pancreatic cancer: a phase II trial of the University of Chicago Phase II Consortium
- (2010) Hedy Lee Kindler et al. INVESTIGATIONAL NEW DRUGS
- C-Myc is a Nrf2-interacting protein that negatively regulates phase II genes through their electrophile responsive elements
- (2010) Smadar Levy et al. IUBMB LIFE
- Glycomic and Transcriptomic Response of GSC11 Glioblastoma Stem Cells to STAT3 Phosphorylation Inhibition and Serum-Induced Differentiation
- (2010) Huan He et al. JOURNAL OF PROTEOME RESEARCH
- Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
- (2010) S. Suzuki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
- (2010) W. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fatty acids and breast cancer: The role of stem cells
- (2010) Kent L. Erickson et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- Targeting breast stem cells with the cancer preventive compounds curcumin and piperine
- (2009) Madhuri Kakarala et al. BREAST CANCER RESEARCH AND TREATMENT
- Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells
- (2009) Tim C.P. Somervaille et al. Cell Stem Cell
- Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
- (2009) Ismael Samudio et al. JOURNAL OF CLINICAL INVESTIGATION
- Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin
- (2009) Francesc X. Soriano et al. MOLECULES AND CELLS
- Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
- (2009) Zachary T. Schafer et al. NATURE
- Association of reactive oxygen species levels and radioresistance in cancer stem cells
- (2009) Maximilian Diehn et al. NATURE
- Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation
- (2009) Edward Owusu-Ansah et al. NATURE
- Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
- (2009) Chen Zhao et al. NATURE
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
- (2009) Dunyaporn Trachootham et al. NATURE REVIEWS DRUG DISCOVERY
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
- (2009) R J DeBerardinis et al. ONCOGENE
- Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells
- (2009) J. Yun et al. SCIENCE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Regulation of Reactive Oxygen Species and Genomic Stability in Hematopoietic Stem Cells
- (2008) Kazuhito Naka et al. ANTIOXIDANTS & REDOX SIGNALING
- Targeting lipophilic cations to mitochondria
- (2008) Michael P. Murphy BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Tumor Cell Metabolism: Cancer's Achilles' Heel
- (2008) Guido Kroemer et al. CANCER CELL
- Cancer stem cells: never Wnt away from the niche
- (2008) Ilaria Malanchi et al. CURRENT OPINION IN ONCOLOGY
- Foxo3 Is Essential for the Regulation of Ataxia Telangiectasia Mutated and Oxidative Stress-mediated Homeostasis of Hematopoietic Stem Cells
- (2008) Safak Yalcin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
- (2008) Pierre Sonveaux et al. JOURNAL OF CLINICAL INVESTIGATION
- The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
- (2008) A. Dubrovska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis
- (2008) K. Ishikawa et al. SCIENCE
- Coordinated Changes of Mitochondrial Biogenesis and Antioxidant Enzymes During Osteogenic Differentiation of Human Mesenchymal Stem Cells
- (2008) Chien-Tsun Chen et al. STEM CELLS
- The Role of PPARs in Cancer
- (2008) Keisuke Tachibana et al. PPAR Research
- 2-Deoxy-d-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer
- (2007) Mitchell C. Coleman et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mechanisms of BSO (L-buthionine-S,R-sulfoximine)-induced cytotoxic effects in neuroblastoma
- (2007) Barbara Marengo et al. FREE RADICAL BIOLOGY AND MEDICINE
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