Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity
出版年份 2012 全文链接
标题
Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity
作者
关键词
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出版物
ONCOGENE
Volume 32, Issue 40, Pages 4825-4835
出版商
Springer Nature
发表日期
2012-10-29
DOI
10.1038/onc.2012.493
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models
- (2011) Ayumu Taguchi et al. CANCER CELL
- Succination of Keap1 and Activation of Nrf2-Dependent Antioxidant Pathways in FH-Deficient Papillary Renal Cell Carcinoma Type 2
- (2011) Lisa Kinch et al. CANCER CELL
- Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling
- (2011) Julie Adam et al. CANCER CELL
- Keap1 Mutations and Nrf2 Pathway Activation in Epithelial Ovarian Cancer
- (2011) P. A. Konstantinopoulos et al. CANCER RESEARCH
- NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1
- (2011) T.-H. Kim et al. CANCER RESEARCH
- miR-200a Regulates Nrf2 Activation by TargetingKeap1mRNA in Breast Cancer Cells
- (2011) Gabriel Eades et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammatory Macrophages Induce Nrf2 Transcription Factor-dependent Proteasome Activity in Colonic NCM460 Cells and Thereby Confer Anti-apoptotic Protection
- (2011) Susanne Sebens et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteasome Inhibition Induces a p38 MAPK Pathway-Dependent Antiapoptotic Program via Nrf2 in Thyroid Cancer Cells
- (2011) Zhen-Xian Du et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Mutation of the Nrf2 gene in non-small cell lung cancer
- (2011) Yi Hu et al. MOLECULAR BIOLOGY REPORTS
- Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy
- (2011) Adam Lister et al. Molecular Cancer
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones
- (2011) Margreet R Olthof et al. Nutrition & Metabolism
- The Nrf2-Keap1-ARE Signaling Pathway: The Regulation and Dual Function of Nrf2 in Cancer
- (2010) Donna D. Zhang ANTIOXIDANTS & REDOX SIGNALING
- Gain of Nrf2 Function in Non-Small-Cell Lung Cancer Cells Confers Radioresistance
- (2010) Anju Singh et al. ANTIOXIDANTS & REDOX SIGNALING
- Functional differences between two major ubiquitin receptors in the proteasome; S5a and hRpn13
- (2010) Muthukumar Elangovan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Feedback regulation of proteasome gene expression and its implications in cancer therapy
- (2010) Youming Xie CANCER AND METASTASIS REVIEWS
- High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer
- (2010) T. Jiang et al. CANCER RESEARCH
- Nrf2 and Keap1 Abnormalities in Non-Small Cell Lung Carcinoma and Association with Clinicopathologic Features
- (2010) L. M. Solis et al. CLINICAL CANCER RESEARCH
- Oxidative stress, inflammation, and cancer: How are they linked?
- (2010) Simone Reuter et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nrf2-ARE stress response mechanism: A control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases
- (2010) Shruti Singh et al. FREE RADICAL RESEARCH
- Hepatitis B Virus Induces Expression of Antioxidant Response Element-regulated Genes by Activation of Nrf2
- (2010) Stephanie Schaedler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nuclear Erythroid Factor 2-mediated Proteasome Activation Delays Senescence in Human Fibroblasts
- (2010) Suzanne Kapeta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression
- (2010) Ute Boettler et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells
- (2010) Senthil K. Radhakrishnan et al. MOLECULAR CELL
- Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop
- (2010) Janos Steffen et al. MOLECULAR CELL
- Nuclear Factor (Erythroid-Derived 2)-Like 2 Regulates Drug Resistance in Pancreatic Cancer Cells
- (2010) Young Bin Hong et al. PANCREAS
- Acute Effects of Decaffeinated Coffee and the Major Coffee Components Chlorogenic Acid and Trigonelline on Glucose Tolerance
- (2009) A. E. van Dijk et al. DIABETES CARE
- Involvement of Nrf2 activation in resistance to 5-fluorouracil in human colon cancer HT-29 cells
- (2009) Hanane Akhdar et al. EUROPEAN JOURNAL OF CANCER
- Acquisition of doxorubicin resistance in ovarian carcinoma cells accompanies activation of the NRF2 pathway
- (2009) Gi-seong Shim et al. FREE RADICAL BIOLOGY AND MEDICINE
- HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA
- (2009) P Fritsche et al. GUT
- Prothymosin-α Mediates Nuclear Import of the INrf2/Cul3·Rbx1 Complex to Degrade Nuclear Nrf2
- (2009) Suryakant K. Niture et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress
- (2009) Truyen Nguyen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin
- (2009) Yoo Ri Kim et al. JOURNAL OF PATHOLOGY
- A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders
- (2009) Jiyoung Kim et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)
- (2009) A Arlt et al. ONCOGENE
- NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
- (2009) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
- Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues
- (2008) Rui Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2
- (2008) X.-J. Wang et al. CARCINOGENESIS
- Increased expression of Nrf2/ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells
- (2008) Sang Kyum Kim et al. FREE RADICAL BIOLOGY AND MEDICINE
- Proteomic Expression Analysis of Surgical Human Colorectal Cancer Tissues: Up-Regulation of PSB7, PRDX1, and SRP9 and Hypoxic Adaptation in Cancer
- (2008) Jung-hyun Rho et al. JOURNAL OF PROTEOME RESEARCH
- Dual roles of Nrf2 in cancer
- (2008) A LAU et al. PHARMACOLOGICAL RESEARCH
- Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults
- (2007) W OSBURN et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
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