标题
Lipid metabolic reprogramming in cancer cells
作者
关键词
-
出版物
Oncogenesis
Volume 5, Issue 1, Pages e189-e189
出版商
Springer Nature
发表日期
2016-01-25
DOI
10.1038/oncsis.2015.49
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Alkylphospholipids – A Promising Class of Chemotherapeutic Agents with a Broad Pharmacological Spectrum
- (2016) Juliana De Almeida Pachioni et al. JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
- The role of lipid droplets and adipocytes in cancer. Raman imaging of cell cultures: MCF10A, MCF7, and MDA-MB-231 compared to adipocytes in cancerous human breast tissue
- (2015) Halina Abramczyk et al. ANALYST
- Label-Free Raman Spectroscopic Imaging Monitors the Integral Physiologically Relevant Drug Responses in Cancer Cells
- (2015) Samir F. El-Mashtoly et al. ANALYTICAL CHEMISTRY
- Cholesterol homeostasis and autophagic flux in perifosine-treated human hepatoblastoma HepG2 and glioblastoma U-87 MG cell lines
- (2015) Pablo Ríos-Marco et al. BIOCHEMICAL PHARMACOLOGY
- Targeting the leukemia cell metabolism by the CPT1a inhibition: functional preclinical effects in leukemias
- (2015) M. R. Ricciardi et al. BLOOD
- Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study
- (2015) David de Gonzalo-Calvo et al. BMC CANCER
- Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis
- (2015) Colin A. Flaveny et al. CANCER CELL
- Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry
- (2015) S. Guenther et al. CANCER RESEARCH
- The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1
- (2015) Wilhelm Palm et al. CELL
- Uncoupling Nuclear Receptor LXR and Cholesterol Metabolism in Cancer
- (2015) Fabiola Bovenga et al. Cell Metabolism
- Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer
- (2015) L. Zhang et al. CLINICAL CANCER RESEARCH
- Mitotane Inhibits Sterol-O-Acyl Transferase 1 Triggering Lipid-Mediated Endoplasmic Reticulum Stress and Apoptosis in Adrenocortical Carcinoma Cells
- (2015) Silviu Sbiera et al. ENDOCRINOLOGY
- Saturated and mono-unsaturated lysophosphatidylcholine metabolism in tumour cells: a potential therapeutic target for preventing metastases
- (2015) Anna Raynor et al. Lipids in Health and Disease
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism
- (2015) Emelyn H. Shroff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma
- (2015) Fabienne Guillaumond et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oncogenes strike a balance between cellular growth and homeostasis
- (2015) Bo Qiu et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- HIF2 -Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma
- (2015) B. Qiu et al. Cancer Discovery
- ColoLipidGene: signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients
- (2015) Teodoro Vargas et al. Oncotarget
- The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination
- (2015) Federica Maione et al. Scientific Reports
- Nelfinavir and Nelfinavir Analogs Block Site-2 Protease Cleavage to Inhibit Castration-Resistant Prostate Cancer
- (2015) Min Guan et al. Scientific Reports
- Stress Responses from the Endoplasmic Reticulum in Cancer
- (2015) Hironori Kato et al. Frontiers in Oncology
- Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness
- (2014) Shuhua Yue et al. Cell Metabolism
- CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models
- (2014) Sun-Hee Kim et al. INVESTIGATIONAL NEW DRUGS
- Aspirin and COX-2 Inhibitor Use in Patients With Stage III Colon Cancer
- (2014) Kimmie Ng et al. JNCI-Journal of the National Cancer Institute
- Cholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma
- (2014) Naoshad Mohammad et al. Molecular Cancer
- Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer
- (2014) I. R. Schlaepfer et al. MOLECULAR CANCER THERAPEUTICS
- Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
- (2014) Antonina V. Kurtova et al. NATURE
- Novel prospects of statins as therapeutic agents in cancer
- (2014) Simona Pisanti et al. PHARMACOLOGICAL RESEARCH
- Cancer Cells Differentially Activate and Thrive on De Novo Lipid Synthesis Pathways in a Low-Lipid Environment
- (2014) Veerle W. Daniëls et al. PLoS One
- Alteration of the lipid profile in lymphomas induced by MYC overexpression
- (2014) L. S. Eberlin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- COX-2 Inhibition Potentiates Antiangiogenic Cancer Therapy and Prevents Metastasis in Preclinical Models
- (2014) L. Xu et al. Science Translational Medicine
- Lipid Droplets: A New Player in Colorectal Cancer Stem Cells Unveiled by Spectroscopic Imaging
- (2014) Luca Tirinato et al. STEM CELLS
- Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment
- (2014) Daniel Ackerman et al. TRENDS IN CELL BIOLOGY
- Involvement of eicosanoids in the pathogenesis of pancreatic cancer: The roles of cyclooxygenase-2 and 5-lipoxygenase
- (2014) Lawrence M Knab WORLD JOURNAL OF GASTROENTEROLOGY
- Direct Visualization of De novo Lipogenesis in Single Living Cells
- (2014) Junjie Li et al. Scientific Reports
- Induction of ER stress-mediated apoptosis by ceramide via disruption of ER Ca2+ homeostasis in human adenoid cystic carcinoma cells
- (2014) Zhe Liu et al. Cell and Bioscience
- Characterization of MYC-Induced Tumorigenesis by in Situ Lipid Profiling
- (2013) Richard H. Perry et al. ANALYTICAL CHEMISTRY
- Alkylphospholipids deregulate cholesterol metabolism and induce cell-cycle arrest and autophagy in U-87 MG glioblastoma cells
- (2013) Pablo Ríos-Marco et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
- (2013) Alicia Llorente et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies
- (2013) Michel Record et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity
- (2013) K. J. Williams et al. CANCER RESEARCH
- High-resolution imaging mass spectrometry reveals detailed spatial distribution of phosphatidylinositols in human breast cancer
- (2013) Masahiro Kawashima et al. CANCER SCIENCE
- Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model
- (2013) N Sanchez-Macedo et al. CELL DEATH AND DIFFERENTIATION
- Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma
- (2013) C. A. von Roemeling et al. CLINICAL CANCER RESEARCH
- Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human Evidence
- (2013) Joao Tomé-Carneiro et al. CURRENT PHARMACEUTICAL DESIGN
- Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development
- (2013) F. Baenke et al. Disease Models & Mechanisms
- On the future of mass-spectrometry-based lipidomics
- (2013) Ursula Loizides-Mangold FEBS Journal
- Membrane lipid saturation activates IRE1α without inducing clustering
- (2013) Yuto Kitai et al. GENES TO CELLS
- Lipid raft regulates the initial spreading of melanoma A375 cells by modulating β1 integrin clustering
- (2013) Ruifei Wang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- CARS based label-free assay for assessment of drugs by monitoring lipid droplets in tumour cells
- (2013) Christian Steuwe et al. Journal of Biophotonics
- Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
- (2013) Cosimo Commisso et al. NATURE
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond
- (2013) Gregory T. Kunkel et al. NATURE REVIEWS DRUG DISCOVERY
- Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
- (2013) J. J. Kamphorst et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains
- (2013) R. Volmer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics
- (2013) Pedro M. R. Cruz et al. Frontiers in Pharmacology
- Non-glucose metabolism in cancer cells—is it all in the fat?
- (2012) Swethajit Biswas et al. CANCER AND METASTASIS REVIEWS
- Metabolic Signatures Uncover Distinct Targets in Molecular Subsets of Diffuse Large B Cell Lymphoma
- (2012) Pilar Caro et al. CANCER CELL
- Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
- (2012) Douglas Hanahan et al. CANCER CELL
- Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer
- (2012) Jie Liang et al. CANCER CELL
- Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
- (2012) M. Nagahashi et al. CANCER RESEARCH
- ATP-Citrate Lyase: A Key Player in Cancer Metabolism
- (2012) N. Zaidi et al. CANCER RESEARCH
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
- (2012) Haoqiang Ying et al. CELL
- Molecular Pathways: Tumor Cells Co-opt the Brain-Specific Metabolism Gene CPT1C to Promote Survival
- (2012) P. T. Reilly et al. CLINICAL CANCER RESEARCH
- Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression
- (2012) I. Mylonis et al. JOURNAL OF CELL SCIENCE
- Targeting tumor cell metabolism with statins
- (2012) J W Clendening et al. ONCOGENE
- Exosomal Lipids Impact Notch Signaling and Induce Death of Human Pancreatic Tumoral SOJ-6 Cells
- (2012) Sadia Beloribi et al. PLoS One
- Multifaceted roles of PGE2 in inflammation and cancer
- (2012) Masako Nakanishi et al. Seminars in Immunopathology
- Targeting the ceramide system in cancer
- (2011) Brian Henry et al. CANCER LETTERS
- Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression
- (2011) M. Hilvo et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6
- (2011) M. Guan et al. CLINICAL CANCER RESEARCH
- Lipid rafts: signaling and sorting platforms of cells and their roles in cancer
- (2011) Simon Staubach et al. Expert Review of Proteomics
- Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
- (2011) K. Zaugg et al. GENES & DEVELOPMENT
- M2 Macrophages Induced by Prostaglandin E2 and IL-6 from Cervical Carcinoma Are Switched to Activated M1 Macrophages by CD4+ Th1 Cells
- (2011) M. Heusinkveld et al. JOURNAL OF IMMUNOLOGY
- A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma
- (2011) S. Torres et al. MOLECULAR CANCER THERAPEUTICS
- Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth
- (2011) D. Gaglio et al. Molecular Systems Biology
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR-Dependent Pathway
- (2011) D. Guo et al. Cancer Discovery
- De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
- (2010) E. Rysman et al. CANCER RESEARCH
- Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro
- (2010) Viviana Anelli et al. FASEB JOURNAL
- Fatty acid synthase as a potential therapeutic target in cancer
- (2010) Richard Flavin et al. Future Oncology
- Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance
- (2010) Suriyan Ponnusamy et al. Future Oncology
- Decrease in Membrane Phospholipid Unsaturation Induces Unfolded Protein Response
- (2010) Hiroyuki Ariyama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The PI3K Pathway As Drug Target in Human Cancer
- (2010) Kevin D. Courtney et al. JOURNAL OF CLINICAL ONCOLOGY
- Shedding new light on lipid biology with coherent anti-Stokes Raman scattering microscopy
- (2010) Thuc T. Le et al. JOURNAL OF LIPID RESEARCH
- Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins
- (2010) Caroline Subra et al. JOURNAL OF LIPID RESEARCH
- Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells
- (2010) A J C Pommier et al. ONCOGENE
- Lipid droplets in inflammation and cancer
- (2010) Patricia T. Bozza et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Lipid Rafts As a Membrane-Organizing Principle
- (2010) D. Lingwood et al. SCIENCE
- Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
- (2009) María Salazar et al. JOURNAL OF CLINICAL INVESTIGATION
- Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
- (2009) Ismael Samudio et al. JOURNAL OF CLINICAL INVESTIGATION
- Lipid raft modulation inhibits NSCLC cell migration through delocalization of the focal adhesion complex
- (2009) Jeong Hee Jeon et al. LUNG CANCER
- Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions
- (2009) M Reis-Sobreiro et al. ONCOGENE
- The role of COX-2 in intestinal inflammation and colorectal cancer
- (2009) D Wang et al. ONCOGENE
- Antimetastatic Effects of Liposomal Gemcitabine and Empty Liposomes in an Orthotopic Mouse Model of Pancreatic Cancer
- (2009) Ralph Graeser et al. PANCREAS
- Involvement of Raft Aggregates Enriched in Fas/CD95 Death-Inducing Signaling Complex in the Antileukemic Action of Edelfosine in Jurkat Cells
- (2009) Consuelo Gajate et al. PLoS One
- Avicin D, a Plant Triterpenoid, Induces Cell Apoptosis by Recruitment of Fas and Downstream Signaling Molecules into Lipid Rafts
- (2009) Zhi-Xiang Xu et al. PLoS One
- Cannabinoids for Cancer Treatment: Progress and Promise
- (2008) S. Sarfaraz et al. CANCER RESEARCH
- Mitochondrial Cholesterol Contributes to Chemotherapy Resistance in Hepatocellular Carcinoma
- (2008) J. Montero et al. CANCER RESEARCH
- Lipid Bodies Are Reservoirs of Cyclooxygenase-2 and Sites of Prostaglandin-E2 Synthesis in Colon Cancer Cells
- (2008) M. T. Accioly et al. CANCER RESEARCH
- Targeting lipid rafts inhibits protein kinase B by disrupting calcium homeostasis and attenuates malignant properties of melanoma cells
- (2008) S. Fedida-Metula et al. CARCINOGENESIS
- Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2-deoxyglucose and etomoxir
- (2008) Emma Hernlund et al. INTERNATIONAL JOURNAL OF CANCER
- Induction of myeloid-derived suppressor cells by tumor exosomes
- (2008) Xiaoyu Xiang et al. INTERNATIONAL JOURNAL OF CANCER
- Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer
- (2008) Michael A. Kiebish et al. JOURNAL OF LIPID RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started