The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond
出版年份 2018 全文链接
标题
The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond
作者
关键词
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出版物
PHYSIOLOGICAL REVIEWS
Volume 99, Issue 1, Pages 115-160
出版商
American Physiological Society
发表日期
2018-10-24
DOI
10.1152/physrev.00045.2017
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Structural principles of tumor necrosis factor superfamily signaling
- (2018) Éva S. Vanamee et al. Science Signaling
- Structural principles of tumor necrosis factor superfamily signaling
- (2018) Éva S. Vanamee et al. Science Signaling
- OX40: Structure and function – What questions remain?
- (2017) Jane Willoughby et al. MOLECULAR IMMUNOLOGY
- Current and emerging therapeutic targets for IBD
- (2017) Markus F. Neurath Nature Reviews Gastroenterology & Hepatology
- Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases
- (2017) Michael Croft et al. Nature Reviews Rheumatology
- Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs
- (2017) Heather Torrey et al. Science Signaling
- Death receptor 6 contributes to autoimmunity in lupus-prone mice
- (2017) Daisuke Fujikura et al. Nature Communications
- Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival
- (2017) Sebastian Horn et al. Cell Reports
- The role of CD27 in anti-viral T-cell immunity
- (2017) Emma J Grant et al. Current Opinion in Virology
- Autoinflammatory Diseases with Periodic Fevers
- (2017) Erdal Sag et al. Current Rheumatology Reports
- Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs
- (2017) Heather Torrey et al. Science Signaling
- Role of Etanercept in the Treatment of Tumor Necrosis Factor Receptor-Associated Periodic Syndrome: Personal Experience and Review of the Literature
- (2017) L. Cantarini et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- Necroptosis and Inflammation
- (2016) Kim Newton et al. Annual Review of Biochemistry
- RANKL/RANK control Brca1 mutation-driven mammary tumors
- (2016) Verena Sigl et al. CELL RESEARCH
- NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions
- (2016) Katerina Vlantis et al. IMMUNITY
- CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice
- (2016) Amanda Poissonnier et al. IMMUNITY
- The Costimulatory Receptor OX40 Inhibits Interleukin-17 Expression through Activation of Repressive Chromatin Remodeling Pathways
- (2016) Xiang Xiao et al. IMMUNITY
- The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses
- (2016) Lindsay K. Ward-Kavanagh et al. IMMUNITY
- Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF–TNF-RII binding in rheumatoid arthritis
- (2016) Dao Xuan Nguyen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Requirement of CD30 expression on CD4 T cells in the pathogenesis of experimental autoimmune encephalomyelitis
- (2016) Koji Shinoda et al. JOURNAL OF NEUROIMMUNOLOGY
- The impact of tabalumab on the kidney in systemic lupus erythematosus: results from two phase 3 randomized, clinical trials
- (2016) B H Rovin et al. LUPUS
- RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers
- (2016) Emma Nolan et al. NATURE MEDICINE
- New insights into the immunopathogenesis of systemic lupus erythematosus
- (2016) George C. Tsokos et al. Nature Reviews Rheumatology
- Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration
- (2016) Yun Dong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The CD27–CD70 pathway and pathogenesis of autoimmune disease
- (2016) Bobby Kwanghoon Han et al. SEMINARS IN ARTHRITIS AND RHEUMATISM
- CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells
- (2016) M Drachsler et al. Cell Death & Disease
- Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction
- (2016) Anthony C. Cruz et al. Nature Communications
- APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis
- (2016) Anna Raimbault et al. Oncotarget
- RANKL/RANK: from bone loss to the prevention of breast cancer
- (2016) Verena Sigl et al. Open Biology
- Endothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesion
- (2016) Liang Gao et al. eLife
- Fas–Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis
- (2016) Elisabetta Volpe et al. Frontiers in Immunology
- Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro
- (2015) Christian Merz et al. ANTI-CANCER DRUGS
- GITR+ regulatory T cells in the treatment of autoimmune diseases
- (2015) Maria Grazia Petrillo et al. AUTOIMMUNITY REVIEWS
- Erratum: The role of CD95 and CD95 ligand in cancer
- (2015) M E Peter et al. CELL DEATH AND DIFFERENTIATION
- CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma
- (2015) M Teodorczyk et al. CELL DEATH AND DIFFERENTIATION
- Targeting the Fas/FasL system in Rheumatoid Arthritis therapy: Promising or risky?
- (2015) Flavia Calmon-Hamaty et al. CYTOKINE
- Regulation of cell fate by lymphotoxin (LT) receptor signalling: Functional differences and similarities of the LT system to other TNF superfamily (TNFSF) members
- (2015) Balid Albarbar et al. CYTOKINE & GROWTH FACTOR REVIEWS
- The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation
- (2015) Kai Xu et al. GENES & DEVELOPMENT
- Role of the TWEAK/Fn14 pathway in autoimmune diseases
- (2015) Wang-Dong Xu et al. IMMUNOLOGIC RESEARCH
- Targeting B-cell maturation antigen in multiple myeloma
- (2015) Yu-Tzu Tai et al. Immunotherapy
- Basophil-associated OX40 Ligand Participates in the Initiation of Th2 Responses during Airway Inflammation
- (2015) Caixia Di et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Paradoxical Expansion of Th1 and Th17 Lymphocytes in Rheumatoid Arthritis Following Infliximab Treatment: a Possible Explanation for a Lack of Clinical Response
- (2015) Rossella Talotta et al. JOURNAL OF CLINICAL IMMUNOLOGY
- The TNF-Family Ligand TL1A and Its Receptor DR3 Promote T Cell–Mediated Allergic Immunopathology by Enhancing Differentiation and Pathogenicity of IL-9–Producing T Cells
- (2015) Arianne C. Richard et al. JOURNAL OF IMMUNOLOGY
- The TNF-family cytokine TL1A: from lymphocyte costimulator to disease co-conspirator
- (2015) Arianne C. Richard et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial
- (2015) Michael Gnant et al. LANCET
- The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth
- (2015) Ditte S. Andersen et al. NATURE
- Glucocorticoid-induced tumor necrosis factor receptor–related protein co-stimulation facilitates tumor regression by inducing IL-9–producing helper T cells
- (2015) Il-Kyu Kim et al. NATURE MEDICINE
- Immunopathogenesis of IBD: current state of the art
- (2015) Heitor S. P. de Souza et al. Nature Reviews Gastroenterology & Hepatology
- TNF biology, pathogenic mechanisms and emerging therapeutic strategies
- (2015) George D. Kalliolias et al. Nature Reviews Rheumatology
- TNF and its receptors in the CNS: The essential, the desirable and the deleterious effects
- (2015) L. Probert NEUROSCIENCE
- Canakinumab efficacy and long-term tocilizumab administration in tumor necrosis factor receptor-associated periodic syndrome (TRAPS)
- (2015) Francesco La Torre et al. RHEUMATOLOGY INTERNATIONAL
- Fas and TRAIL ‘death receptors’ as initiators of inflammation: Implications for cancer
- (2015) Sean P. Cullen et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Smac mimetics as IAP antagonists
- (2015) Simone Fulda SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Caspase Functions in Cell Death and Disease: Figure 1.
- (2015) David R. McIlwain et al. Cold Spring Harbor Perspectives in Biology
- Erratum: FAS-ligand regulates differential activation-induced cell death of human T-helper 1 and 17 cells in healthy donors and multiple sclerosis patients
- (2015) M T Cencioni et al. Cell Death & Disease
- Enhanced CD8 T Cell Responses through GITR-Mediated Costimulation Resolve Chronic Viral Infection
- (2015) Maria Fernanda Pascutti et al. PLoS Pathogens
- Role of tumor necrosis factor superfamily in neuroinflammation and autoimmunity
- (2015) Sandip Sonar Frontiers in Immunology
- Efficacy and safety of atacicept for prevention of flares in patients with moderate-to-severe systemic lupus erythematosus (SLE): 52-week data (APRIL-SLE randomised trial)
- (2014) David Isenberg et al. ANNALS OF THE RHEUMATIC DISEASES
- The CD95/CD95L signaling pathway: A role in carcinogenesis
- (2014) Amélie Fouqué et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis
- (2014) James A. Rickard et al. CELL
- A Phase II, Randomized, Study of Weekly APG101+Reirradiation versus Reirradiation in Progressive Glioblastoma
- (2014) W. Wick et al. CLINICAL CANCER RESEARCH
- Key facts and hot spots on tumor necrosis factor receptor‐associated periodic syndrome
- (2014) Donato Rigante et al. CLINICAL RHEUMATOLOGY
- Ectodysplasin A (EDA) – EDA receptor signalling and its pharmacological modulation
- (2014) Christine Kowalczyk-Quintas et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Cell-specific and context-dependent effects of GITR in cancer, autoimmunity, and infection
- (2014) Derek L. Clouthier et al. CYTOKINE & GROWTH FACTOR REVIEWS
- OX40/OX40L Costimulation Affects Induction of Foxp3+ Regulatory T Cells in Part by Expanding Memory T Cells In Vivo
- (2014) X. Xiao et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells
- (2014) X. Chen et al. JOURNAL OF IMMUNOLOGY
- CD40 on APCs Is Needed for Optimal Programming, Maintenance, and Recall of CD8+ T Cell Memory Even in the Absence of CD4+ T Cell Help
- (2014) M. G. H. Hernandez et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: The Dependence of Plasma Cells and Independence of Memory B Cells on BAFF and APRIL
- (2014) M. J. Benson et al. JOURNAL OF IMMUNOLOGY
- Anti-GITR Agonist Therapy Intrinsically Enhances CD8 T Cell Responses to Chronic Lymphocytic Choriomeningitis Virus (LCMV), Thereby Circumventing LCMV-Induced Downregulation of Costimulatory GITR Ligand on APC
- (2014) Derek L. Clouthier et al. JOURNAL OF IMMUNOLOGY
- Differential Impact of CD27 and 4-1BB Costimulation on Effector and Memory CD8 T Cell Generation following Peptide Immunization
- (2014) J. E. Willoughby et al. JOURNAL OF IMMUNOLOGY
- Impaired B Cell Receptor Signaling Is Responsible for Reduced TACI Expression and Function in X-Linked Immunodeficient Mice
- (2014) K. Uslu et al. JOURNAL OF IMMUNOLOGY
- Tumour Necrosis Factor Superfamily Members in the Pathogenesis of Inflammatory Bowel Disease
- (2014) Tomasz J. Ślebioda et al. MEDIATORS OF INFLAMMATION
- Phase II dose–response study of abatacept in Japanese patients with active rheumatoid arthritis with an inadequate response to methotrexate
- (2014) Tsutomu Takeuchi et al. Modern Rheumatology
- Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
- (2014) Huayi Wang et al. MOLECULAR CELL
- RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
- (2014) Nozomi Takahashi et al. NATURE
- RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
- (2014) Marius Dannappel et al. NATURE
- Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells
- (2014) Shawn A Mahmud et al. NATURE IMMUNOLOGY
- The BAFF/APRIL system in SLE pathogenesis
- (2014) Fabien B. Vincent et al. Nature Reviews Rheumatology
- TNF inhibitors – Mechanisms of action, approved and off-label indications
- (2014) Grzegorz Cessak et al. Pharmacological Reports
- Roles of ligands from the TNF superfamily in B cell development, function, and regulation
- (2014) William A. Figgett et al. SEMINARS IN IMMUNOLOGY
- Ectodysplasin research—Where to next?
- (2014) Sylvie Lefebvre et al. SEMINARS IN IMMUNOLOGY
- The Drosophila TNF ortholog Eiger: Emerging physiological roles and evolution of the TNF system
- (2014) Tatsushi Igaki et al. SEMINARS IN IMMUNOLOGY
- Toward understanding ubiquitin-modifying enzymes: from pharmacological targeting to proteomics
- (2014) Jennie R. Lill et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Tumor Necrosis Factor Superfamily in Innate Immunity and Inflammation
- (2014) John Šedý et al. Cold Spring Harbor Perspectives in Biology
- Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
- (2014) Q Remijsen et al. Cell Death & Disease
- Selective Tumor Necrosis Factor Receptor I Blockade Is Antiinflammatory and Reveals Immunoregulatory Role of Tumor Necrosis Factor Receptor II in Collagen-Induced Arthritis
- (2014) Fiona E. McCann et al. Arthritis & Rheumatology
- Biology of the RANKL–RANK–OPG System in Immunity, Bone, and Beyond
- (2014) Matthew C. Walsh et al. Frontiers in Immunology
- Successful Treatment of Tumor Necrosis Factor Receptor–Associated Periodic Syndrome With Canakinumab
- (2013) Maria Giuseppina Brizi et al. ANNALS OF INTERNAL MEDICINE
- Demyelination and other neurological adverse events after anti-TNF therapy
- (2013) Evripidis Kaltsonoudis et al. AUTOIMMUNITY REVIEWS
- CD95L Cell Surface Cleavage Triggers a Prometastatic Signaling Pathway in Triple-Negative Breast Cancer
- (2013) M. Malleter et al. CANCER RESEARCH
- Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
- (2013) Jianfeng Wu et al. CELL RESEARCH
- The Hyper IgM Syndromes
- (2013) Nashmia Qamar et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Anti-TWEAK Monoclonal Antibody in Patients With Rheumatoid Arthritis
- (2013) Nicolas Wisniacki et al. CLINICAL THERAPEUTICS
- The BAFF/APRIL system: Emerging functions beyond B cell biology and autoimmunity
- (2013) Fabien B. Vincent et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Treating multiple sclerosis with monoclonal antibodies: a 2013 update
- (2013) Annika Deiß et al. Expert Review of Neurotherapeutics
- The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
- (2013) James M. Murphy et al. IMMUNITY
- CD30: from basic research to cancer therapy
- (2013) Hiromi Muta et al. IMMUNOLOGIC RESEARCH
- The contextual role of TNFR family members in CD8+T-cell control of viral infections
- (2013) Michael E. Wortzman et al. IMMUNOLOGICAL REVIEWS
- Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling
- (2013) Wanze Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD4+T helper cells use CD154–CD40 interactions to counteract T reg cell–mediated suppression of CD8+T cell responses to influenza
- (2013) André Ballesteros-Tato et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+regulatory T cell development via the CD27–CD70 pathway
- (2013) Jonathan M. Coquet et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TNF-like Ligand 1A (TL1A) Gene Knockout Leads to Ameliorated Collagen-Induced Arthritis in Mice: Implication of TL1A in Humoral Immune Responses
- (2013) X. Wang et al. JOURNAL OF IMMUNOLOGY
- The Role of TL1A and DR3 in Autoimmune and Inflammatory Diseases
- (2013) Yoshihiro Aiba et al. MEDIATORS OF INFLAMMATION
- Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
- (2013) Zhenyu Cai et al. NATURE CELL BIOLOGY
- Clinical targeting of the TNF and TNFR superfamilies
- (2013) Michael Croft et al. NATURE REVIEWS DRUG DISCOVERY
- Structural determinants of DISC function: New insights into death receptor-mediated apoptosis signalling
- (2013) Tamas Sessler et al. PHARMACOLOGY & THERAPEUTICS
- Nonredundant Function of Soluble LT 3 Produced by Innate Lymphoid Cells in Intestinal Homeostasis
- (2013) A. A. Kruglov et al. SCIENCE
- CD95 in cancer: tool or target?
- (2013) Ana Martin-Villalba et al. TRENDS IN MOLECULAR MEDICINE
- Mitochondrial Regulation of Cell Death
- (2013) S. W. G. Tait et al. Cold Spring Harbor Perspectives in Biology
- Death Receptor-Ligand Systems in Cancer, Cell Death, and Inflammation
- (2013) H. Walczak Cold Spring Harbor Perspectives in Biology
- Death receptor 6 (DR6) antagonist antibody is neuroprotective in the mouse SOD1G93A model of amyotrophic lateral sclerosis
- (2013) G Huang et al. Cell Death & Disease
- The TNF receptor-ligands 4-1BB-4-1BBL and GITR-GITRL in NK cell responses
- (2013) Isabel Barao Frontiers in Immunology
- CD40-Mediated Activation of the NF-κB2 Pathway
- (2013) Bruce S. Hostager et al. Frontiers in Immunology
- Regulation of PI-3-Kinase and Akt Signaling in T Lymphocytes and Other Cells by TNFR Family Molecules
- (2013) Takanori So et al. Frontiers in Immunology
- CD27 Signaling Increases the Frequency of Regulatory T Cells and Promotes Tumor Growth
- (2012) C. Claus et al. CANCER RESEARCH
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis
- (2012) Jixi Li et al. CELL
- Signal transduction by tumor necrosis factor receptors
- (2012) Lucía Cabal-Hierro et al. CELLULAR SIGNALLING
- CD40 agonist antibody mediated improvement of chronic Cryptosporidium infection in patients with X-linked hyper IgM syndrome
- (2012) Xiying Fan et al. CLINICAL IMMUNOLOGY
- The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T-cell immunity
- (2012) Jason P. Twohig et al. FASEB JOURNAL
- The CD27 and CD70 Costimulatory Pathway Inhibits Effector Function of T Helper 17 Cells and Attenuates Associated Autoimmunity
- (2012) Jonathan M. Coquet et al. IMMUNITY
- Neutralization of Membrane TNF, but Not Soluble TNF, Is Crucial for the Treatment of Experimental Colitis
- (2012) Clémentine Perrier et al. INFLAMMATORY BOWEL DISEASES
- Pharmacokinetics, pharmacodynamics, safety and tolerability of APG101, a CD95-Fc fusion protein, in healthy volunteers and two glioma patients
- (2012) Jochen Tuettenberg et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- TNF signaling drives myeloid-derived suppressor cell accumulation
- (2012) Xueqiang Zhao et al. JOURNAL OF CLINICAL INVESTIGATION
- Biophysical mechanism of T-cell receptor triggering in a reconstituted system
- (2012) John R. James et al. NATURE
- Lymphotoxin regulates commensal responses to enable diet-induced obesity
- (2012) Vaibhav Upadhyay et al. NATURE IMMUNOLOGY
- Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab
- (2012) David L. Lacey et al. NATURE REVIEWS DRUG DISCOVERY
- CD8+T Cells: GITR Matters
- (2012) Simona Ronchetti et al. TheScientificWorldJOURNAL
- Emerging Functions of RANKL in Lymphoid Tissues
- (2012) Christopher G. Mueller et al. Frontiers in Immunology
- Role of interleukin-6 in a patient with tumor necrosis factor receptor-associated periodic syndrome: Assessment of outcomes following treatment with the anti-interleukin-6 receptor monoclonal antibody tocilizumab
- (2011) Prashantha M. Vaitla et al. ARTHRITIS AND RHEUMATISM
- A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus
- (2011) Richard Furie et al. ARTHRITIS AND RHEUMATISM
- FLIPLinduces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
- (2011) Cristina Pop et al. BIOCHEMICAL JOURNAL
- Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand
- (2011) A. Jain et al. BLOOD
- Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
- (2011) L Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Lymphotoxin Controls the IL-22 Protection Pathway in Gut Innate Lymphoid Cells during Mucosal Pathogen Challenge
- (2011) Alexei V. Tumanov et al. Cell Host & Microbe
- 4-1BB signaling beyond T cells
- (2011) Dass S Vinay et al. Cellular & Molecular Immunology
- CD95-mediated cell signaling in cancer: mutations and post-translational modulations
- (2011) Sébastien Tauzin et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Effector T-cell subsets in systemic lupus erythematosus
- (2011) Min S. Shin et al. CURRENT OPINION IN RHEUMATOLOGY
- Origin and evolution of TNF and TNF receptor superfamilies
- (2011) Gregory D. Wiens et al. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
- The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion
- (2011) Ernst J A Steller et al. EMBO REPORTS
- FAS mRNA editing in human systemic lupus erythematosus
- (2011) Jianming Wu et al. HUMAN MUTATION
- The Costimulatory Molecule CD27 Maintains Clonally Diverse CD8+ T Cell Responses of Low Antigen Affinity to Protect against Viral Variants
- (2011) Klaas P.J.M. van Gisbergen et al. IMMUNITY
- OX40 and CD30 signals in CD4+ T-cell effector and memory function: a distinct role for lymphoid tissue inducer cells in maintaining CD4+ T-cell memory but not effector function
- (2011) David R. Withers et al. IMMUNOLOGICAL REVIEWS
- TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses
- (2011) Linda C. Burkly et al. IMMUNOLOGICAL REVIEWS
- TL1A and DR3, a TNF family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation
- (2011) Françoise Meylan et al. IMMUNOLOGICAL REVIEWS
- Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease
- (2011) Robert C. Rickert et al. IMMUNOLOGICAL REVIEWS
- The regulation and role of T follicular helper cells in immunity
- (2011) Elissa K. Deenick et al. IMMUNOLOGY
- CD27-deficient mice show normal NK-cell differentiation but impaired function upon stimulation
- (2011) Veerle De Colvenaer et al. IMMUNOLOGY AND CELL BIOLOGY
- Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
- (2011) Ariel C. Bulua et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice
- (2011) Fabrina M.Gaspal et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lymphotoxin Signal Promotes Thymic Organogenesis by Eliciting RANK Expression in the Embryonic Thymic Stroma
- (2011) Y. Mouri et al. JOURNAL OF IMMUNOLOGY
- B Cell and BAFF Dependence of IFN- -Exaggerated Disease in Systemic Lupus Erythematosus-Prone NZM 2328 Mice
- (2011) N. Jacob et al. JOURNAL OF IMMUNOLOGY
- CD70 Is Selectively Expressed on Th1 but Not on Th2 Cells and Is Required for Th1-Type Immune Responses
- (2011) Tatsuyoshi Kawamura et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial
- (2011) Sandra V Navarra et al. LANCET
- cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
- (2011) Maria Feoktistova et al. MOLECULAR CELL
- The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
- (2011) Tencho Tenev et al. MOLECULAR CELL
- SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
- (2011) Fuminori Tokunaga et al. NATURE
- FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR
- (2011) Trever G. Bivona et al. NATURE
- Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis
- (2011) Andrew Oberst et al. NATURE
- SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
- (2011) Fumiyo Ikeda et al. NATURE
- Linear ubiquitination prevents inflammation and regulates immune signalling
- (2011) Björn Gerlach et al. NATURE
- IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium
- (2011) Naruhisa Ota et al. NATURE IMMUNOLOGY
- Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination
- (2011) Sha Mi et al. NATURE MEDICINE
- CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) 2, and prevents death-inducing signaling complex formation
- (2011) N. Khadra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LTβR signaling in dendritic cells induces a type I IFN response that is required for optimal clonal expansion of CD8+T cells
- (2011) Leslie Summers deLuca et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Disease causing mutations in the TNF and TNFR superfamilies: Focus on molecular mechanisms driving disease
- (2011) Adrian A. Lobito et al. TRENDS IN MOLECULAR MEDICINE
- The Naturally Processed CD95L Elicits a c-Yes/Calcium/PI3K-Driven Cell Migration Pathway
- (2011) Sébastien Tauzin et al. PLOS BIOLOGY
- Activation of OX40 Augments Th17 Cytokine Expression and Antigen-Specific Uveitis
- (2010) Zili Zhang et al. AMERICAN JOURNAL OF PATHOLOGY
- Control of Immunity by the TNFR-Related Molecule OX40 (CD134)
- (2010) Michael Croft Annual Review of Immunology
- ARG098, a novel anti-human Fas antibody, suppresses synovial hyperplasia and prevents cartilage destruction in a severe combined immunodeficient-HuRAg mouse model
- (2010) Noriko Odani-Kawabata et al. BMC MUSCULOSKELETAL DISORDERS
- Non-canonical NF-κB signaling pathway
- (2010) Shao-Cong Sun CELL RESEARCH
- Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8+ T cells
- (2010) Ian R. Humphreys et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- TRAIL receptor signaling and therapeutics
- (2010) Junaid Abdulghani et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Oncogenic K-Ras Turns Death Receptors Into Metastasis-Promoting Receptors in Human and Mouse Colorectal Cancer Cells
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