Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells

Activation of NF- B1 by OX40 Contributes to Antigen-Driven T Cell Expansion and Survival

(2014) J. Song et al.   JOURNAL OF IMMUNOLOGY

Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals

(2013) Xuguang Tai et al.   IMMUNITY

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+regulatory T cell development via the CD27–CD70 pathway

(2013) Jonathan M. Coquet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TNFR2 Is Critical for the Stabilization of the CD4+Foxp3+ Regulatory T Cell Phenotype in the Inflammatory Environment

(2013) X. Chen et al.   JOURNAL OF IMMUNOLOGY

Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis

(2013) Takashi Sekiya et al.   NATURE IMMUNOLOGY

Murine thymic selection quantified using a unique method to capture deleted T cells

(2013) G. L. Stritesky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selection of Self-Reactive T Cells in the Thymus

(2012) Gretta L. Stritesky et al.   Annual Review of Immunology

A Broad Range of Self-Reactivity Drives Thymic Regulatory T Cell Selection to Limit Responses to Self

(2012) Hyang-Mi Lee et al.   IMMUNITY

IL-2 Receptor Signaling Is Essential for the Development of Klrg1+ Terminally Differentiated T Regulatory Cells

(2012) G. Cheng et al.   JOURNAL OF IMMUNOLOGY

Type 1 Diabetes-Associated IL2RA Variation Lowers IL-2 Signaling and Contributes to Diminished CD4+CD25+ Regulatory T Cell Function

(2012) G. Garg et al.   JOURNAL OF IMMUNOLOGY

The Tumor Necrosis Factor Receptor Stalk Regions Define Responsiveness to Soluble versus Membrane-Bound Ligand

(2012) C. Richter et al.   MOLECULAR AND CELLULAR BIOLOGY

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Anti-tumor effects of depleting and non-depleting anti-CD27 monoclonal antibodies in immune-competent mice

(2010) Tamami Sakanishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

c-Rel but not NF-κB1 is important for T regulatory cell development

(2010) Elissa K. Deenick et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD28 Facilitates the Generation of Foxp3- Cytokine Responsive Regulatory T Cell Precursors

(2010) C. W. J. Lio et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: CD28 and c-Rel-Dependent Pathways Initiate Regulatory T Cell Development

(2010) K. B. Vang et al.   JOURNAL OF IMMUNOLOGY

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

(2010) Ye Zheng et al.   NATURE

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

(2009) Li-Fan Lu et al.   IMMUNITY

Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor

(2009) Meixiao Long et al.   IMMUNITY

Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

(2009) Qingguo Ruan et al.   IMMUNITY

c-Rel is required for the development of thymic Foxp3+CD4 regulatory T cells

(2009) Iwao Isomura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thymic OX40 Expression Discriminates Cells Undergoing Strong Responses to Selection Ligands

(2009) M. Klinger et al.   JOURNAL OF IMMUNOLOGY

Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

(2008) Matthew A. Burchill et al.   IMMUNITY

A Two-Step Process for Thymic Regulatory T Cell Development

(2008) Chan-Wang Joaquim Lio et al.   IMMUNITY