New insights into the immunopathogenesis of systemic lupus erythematosus

Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification

(2016) Melissa E Munroe et al.   ANNALS OF THE RHEUMATIC DISEASES

A meta-analysis of serum and cerebrospinal fluid autoantibodies in neuropsychiatric systemic lupus erythematosus

(2016) Roger C. Ho et al.   AUTOIMMUNITY REVIEWS

Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients

(2016) Romain Banchereau et al.   CELL

Specific HDAC6 inhibition by ACY-738 reduces SLE pathogenesis in NZB/W mice

(2016) Nicole L. Regna et al.   CLINICAL IMMUNOLOGY

Increased 5-hydroxymethylcytosine in CD4 + T cells in systemic lupus erythematosus

(2016) Ming Zhao et al.   JOURNAL OF AUTOIMMUNITY

Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies

(2016) Rufei Lu et al.   JOURNAL OF AUTOIMMUNITY

Genetic Variants That Are Associated with Neuropsychiatric Systemic Lupus Erythematosus

(2016) R. C. Ho et al.   JOURNAL OF RHEUMATOLOGY

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

Lupus Nephritis IgG Induction of Calcium/Calmodulin-Dependent Protein Kinase IV Expression in Podocytes and Alteration of Their Function

(2016) Kunihiro Ichinose et al.   Arthritis & Rheumatology

Epigenetic Reprogramming in Naive CD4+ T Cells Favoring T Cell Activation and Non-Th1 Effector T Cell Immune Response as an Early Event in Lupus Flares

(2016) Patrick Coit et al.   Arthritis & Rheumatology

Circulating Apoptotic Microparticles in Systemic Lupus Erythematosus Patients Drive the Activation of Dendritic Cell Subsets and Prime Neutrophils for NETosis

(2016) Jürgen Dieker et al.   Arthritis & Rheumatology

Mutations in DDX58, which Encodes RIG-I, Cause Atypical Singleton-Merten Syndrome

(2015) Mi-Ae Jang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Characterization of human disease phenotypes associated with mutations inTREX1,RNASEH2A,RNASEH2B,RNASEH2C,SAMHD1,ADAR, andIFIH1

(2015) Yanick J. Crow et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Significance of CD163-Positive Macrophages in Proliferative Glomerulonephritis

(2015) Jun Li et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

(2015) Dag Leonard et al.   ANNALS OF THE RHEUMATIC DISEASES

Monoclonal antibody against macrophage colony-stimulating factor suppresses circulating monocytes and tissue macrophage function but does not alter cell infiltration/activation in cutaneous lesions or clinical outcomes in patients with cutaneous lupus ery

(2015) K. Masek-Hammerman et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Impact of dietary deviation on disease progression and gut microbiome composition in lupus-prone SNF1mice

(2015) B. M. Johnson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Glomerular cytokine expression in murine lupus nephritis

(2015) Kadiombo Anastasie Tshilela et al.   Clinical and Experimental Nephrology

The effect of mycophenolic acid on epigenetic modifications in lupus CD4+T cells

(2015) Yang Yang et al.   CLINICAL IMMUNOLOGY

The role of neutrophils in the pathogenesis of systemic lupus erythematosus

(2015) Carolyne K. Smith et al.   CURRENT OPINION IN RHEUMATOLOGY

Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity

(2015) Roba M. Talaat et al.   CYTOKINE

Commensal microbiota influence systemic autoimmune responses

(2015) J. T. Van Praet et al.   EMBO JOURNAL

Ultraviolet light converts propranolol, a nonselective β-blocker and potential lupus-inducing drug, into a proinflammatory AhR ligand

(2015) Karim Dorgham et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Increased expression of TLR2 in CD4+T cells from SLE patients enhances immune reactivity and promotes IL-17 expression through histone modifications

(2015) Yu Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Amyloid-DNA Composites of Bacterial Biofilms Stimulate Autoimmunity

(2015) Paul M. Gallo et al.   IMMUNITY

OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response

(2015) Clément Jacquemin et al.   IMMUNITY

Therapeutic targeting of BET protein BRD4 delays murine lupus

(2015) Shitong Wei et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

HDAC expression and activity is upregulated in diseased lupus-prone mice

(2015) Nicole L. Regna et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus and erosive arthritis

(2015) Jolan E. Walter et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus

(2015) William E. O'Gorman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells

(2015) Patrick Coit et al.   JOURNAL OF AUTOIMMUNITY

Widely divergent transcriptional patterns between SLE patients of different ancestral backgrounds in sorted immune cell populations

(2015) Shruti Sharma et al.   JOURNAL OF AUTOIMMUNITY

Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production

(2015) Anja Brehm et al.   JOURNAL OF CLINICAL INVESTIGATION

IRF5 Deficiency Ameliorates Lupus but Promotes Atherosclerosis and Metabolic Dysfunction in a Mouse Model of Lupus-Associated Atherosclerosis

(2015) Amanda A. Watkins et al.   JOURNAL OF IMMUNOLOGY

Self-reactive IgE exacerbates interferon responses associated with autoimmunity

(2015) Jill Henault et al.   NATURE IMMUNOLOGY

The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity

(2015) Zaida G Ramirez-Ortiz et al.   NATURE IMMUNOLOGY

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

(2015) Yun R Li et al.   NATURE MEDICINE

RNA sensing by conventional dendritic cells is central to the development of lupus nephritis

(2015) Teja Celhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression

(2015) T. Hung et al.   SCIENCE

Local synthesis of interferon-alpha in lupus nephritis is associated with type I interferons signature and LMP7 induction in renal tubular epithelial cells

(2015) Giuseppe Castellano et al.   ARTHRITIS RESEARCH & THERAPY

Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice

(2015) Jürgen Dieker et al.   ARTHRITIS RESEARCH & THERAPY

Pathophysiology of cutaneous lupus erythematosus

(2015) Jordan C Achtman et al.   ARTHRITIS RESEARCH & THERAPY

Monocyte enhancers are highly altered in systemic lupus erythematosus

(2015) Lihua Shi et al.   Epigenomics

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci

(2015) Paul Martin et al.   Nature Communications

The Role of MicroRNAs and Human Epidermal Growth Factor Receptor 2 in Proliferative Lupus Nephritis

(2015) Patrícia Costa-Reis et al.   Arthritis & Rheumatology

Interferon Regulatory Factor 1 Marks Activated Genes and Can Induce Target Gene Expression in Systemic Lupus Erythematosus

(2015) Zhe Zhang et al.   Arthritis & Rheumatology

Circulating Follicular Helper-Like T Cells in Systemic Lupus Erythematosus: Association With Disease Activity

(2015) Jin-Young Choi et al.   Arthritis & Rheumatology

Brief Report: Interleukin-38 Exerts Antiinflammatory Functions and Is Associated With Disease Activity in Systemic Lupus Erythematosus

(2015) Ina Rudloff et al.   Arthritis & Rheumatology

High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination

(2015) Kaval Kaur et al.   PLoS One

Gene Expression Profiles from Disease Discordant Twins Suggest Shared Antiviral Pathways and Viral Exposures among Multiple Systemic Autoimmune Diseases

(2015) Lu Gan et al.   PLoS One

T Cell Transcriptomes Describe Patient Subtypes in Systemic Lupus Erythematosus

(2015) Sean J. Bradley et al.   PLoS One

Aicardi–Goutières syndrome harbours abundant systemic and brain-reactive autoantibodies

(2014) Eloy Cuadrado et al.   ANNALS OF THE RHEUMATIC DISEASES

Reactive Oxygen Species Deficiency Induces Autoimmunity with Type 1 Interferon Signature

(2014) Tiina Kelkka et al.   ANTIOXIDANTS & REDOX SIGNALING

Dynamics of Gut Microbiota in Autoimmune Lupus

(2014) Husen Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice

(2014) Parisa Sinai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammatory manifestations in a single-center cohort of patients with chronic granulomatous disease

(2014) Alessandra Magnani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Autoimmunity due to RAG deficiency and estimated disease incidence in RAG1/2 mutations

(2014) Karin Chen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immunoglobulin E plays an immunoregulatory role in lupus

(2014) Barbara Dema et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

(2014) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

Lupus Nephritis Susceptibility Loci in Women with Systemic Lupus Erythematosus

(2014) S. A. Chung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Viruses as potential pathogenic agents in systemic lupus erythematosus

(2014) P Nelson et al.   LUPUS

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

(2014) Xianqin Zhang et al.   NATURE

Genetic and epigenetic fine mapping of causal autoimmune disease variants

(2014) Kyle Kai-How Farh et al.   NATURE

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones

(2014) Tomohiko Kanno et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Activated STING in a Vascular and Pulmonary Syndrome

(2014) Yin Liu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autoreactive IgE Is Prevalent in Systemic Lupus Erythematosus and Is Associated with Increased Disease Activity and Nephritis

(2014) Barbara Dema et al.   PLoS One

The SLE Transcriptome Exhibits Evidence of Chronic Endotoxin Exposure and Has Widespread Dysregulation of Non-Coding and Coding RNAs

(2014) Lihua Shi et al.   PLoS One

Decreased miR-26a Expression Correlates with the Progression of Podocyte Injury in Autoimmune Glomerulonephritis

(2014) Osamu Ichii et al.   PLoS One

Cell Distance Mapping Identifies Functional T Follicular Helper Cells in Inflamed Human Renal Tissue

(2014) V. M. Liarski et al.   Science Translational Medicine

Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus

(2014) Anders A Bengtsson et al.   ARTHRITIS RESEARCH & THERAPY

Intestinal Dysbiosis Associated with Systemic Lupus Erythematosus

(2014) A. Hevia et al.   mBio

Impaired Suppressive Capacity of Activation-Induced Regulatory B Cells in Systemic Lupus Erythematosus

(2014) Nele Gao et al.   Arthritis & Rheumatology

MicroRNA Regulation in Systemic Lupus Erythematosus Pathogenesis

(2014) Sheng Yan et al.   Immune Network

MicroRNA-30a Promotes B Cell Hyperactivity in Patients With Systemic Lupus Erythematosus by Direct Interaction With Lyn

(2013) Yu Liu et al.   ARTHRITIS AND RHEUMATISM

Protein Kinase Cδ Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell-Defective Apoptosis and Hyperproliferation

(2013) Alexandre Belot et al.   ARTHRITIS AND RHEUMATISM

Circulating MicroRNA Expression Profiles Associated With Systemic Lupus Erythematosus

(2013) Anting Liu Carlsen et al.   ARTHRITIS AND RHEUMATISM

A T cell gene expression panel for the diagnosis and monitoring of disease activity in patients with systemic lupus erythematosus

(2013) Alexandros P. Grammatikos et al.   CLINICAL IMMUNOLOGY

Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptor

(2013) Marton Keszei et al.   FASEB JOURNAL

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

(2013) Patrick Coit et al.   JOURNAL OF AUTOIMMUNITY

Genetic susceptibility to SLE: Recent progress from GWAS

(2013) Yong Cui et al.   JOURNAL OF AUTOIMMUNITY

Neuropsychiatric disease in murine lupus is dependent on the TWEAK/Fn14 pathway

(2013) Jing Wen et al.   JOURNAL OF AUTOIMMUNITY

Using microRNA as an Alternative Treatment for Hyperlipidemia and Cardiovascular Disease

(2013) Elizabeth J. Hennessy et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Clinical Manifestations of Disease in X-Linked Carriers of Chronic Granulomatous Disease

(2013) A. C. Battersby et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Cgnz1allele confers kidney resistance to damage preventing progression of immune complex–mediated acute lupus glomerulonephritis

(2013) Yan Ge et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired phagocytosis and susceptibility to infection in pediatric-onset systemic lupus erythematosus

(2013) S-A Wu et al.   LUPUS

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

MicroRNAs of the miR-17∼92 family are critical regulators of TFH differentiation

(2013) Seung Goo Kang et al.   NATURE IMMUNOLOGY

T Follicular Helper Cells Mediate Expansion of Regulatory B Cells via IL-21 in Lupus-Prone MRL/lpr Mice

(2013) Xue Yang et al.   PLoS One

Circulating TFH Subset Distribution Is Strongly Affected in Lupus Patients with an Active Disease

(2013) Carole Le Coz et al.   PLoS One

Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Faslpr mouse

(2013) T.-H. Thai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Are RASopathies new monogenic predisposing conditions to the development of systemic lupus erythematosus? Case report and systematic review of the literature

(2013) Brigitte Bader-Meunier et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production

(2013) Julio E. Molineros et al.   PLoS Genetics

Treatment with Anti-Interleukin 23 Antibody Ameliorates Disease in Lupus-Prone Mice

(2013) Vasileios C. Kyttaris et al.   Biomed Research International

Unraveling Multiple MHC Gene Associations with Systemic Lupus Erythematosus: Model Choice Indicates a Role for HLA Alleles and Non-HLA Genes in Europeans

(2012) David L. Morris et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Brief Report: Large-scale analysis of tumor necrosis factor α levels in systemic lupus erythematosus

(2012) Corinna E. Weckerle et al.   ARTHRITIS AND RHEUMATISM

Increased IgE serum levels are unrelated to allergic and parasitic diseases in patients with juvenile systemic lupus erythematosus

(2012) BL Liphaus et al.   Clinics

Interferon-inducible Ifi200-family genes as modifiers of lupus susceptibility

(2012) Divaker Choubey   IMMUNOLOGY LETTERS

TLR9 drives the development of transitional B cells towards the marginal zone pathway and promotes autoimmunity

(2012) Thomas Guerrier et al.   JOURNAL OF AUTOIMMUNITY

Association of Fas gene polymorphisms with systemic lupus erythematosus: a meta-analysis

(2012) Nan Xiang et al.   MOLECULAR BIOLOGY REPORTS

PDTC attenuate LPS-induced kidney injury in systemic lupus erythematosus-prone MRL/lpr Mice

(2012) Jin-Xia Zhai et al.   MOLECULAR BIOLOGY REPORTS

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

Monogenic forms of systemic lupus erythematosus: new insights into SLE pathogenesis

(2012) Alexandre Belot et al.   Pediatric Rheumatology

NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus

(2012) A. M. Campbell et al.   Science Translational Medicine

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression

(2011) E. Stagakis et al.   ANNALS OF THE RHEUMATIC DISEASES

A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

(2011) Richard Furie et al.   ARTHRITIS AND RHEUMATISM

Prolactin and autoimmunity

(2011) Shahar Shelly et al.   AUTOIMMUNITY REVIEWS

B cells and autoimmunity

(2011) Shiv Pillai et al.   CURRENT OPINION IN IMMUNOLOGY

Regulatory T-cells in systemic lupus erythematosus and rheumatoid arthritis

(2011) Konstantia-Maria Chavele et al.   FEBS LETTERS

Monocyte polarization: the relationship of genome-wide changes in H4 acetylation with polarization

(2011) Z Zhang et al.   GENES AND IMMUNITY

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

(2011) B Namjou et al.   GENES AND IMMUNITY

Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking

(2011) Ryutaro Fukui et al.   IMMUNITY

Aicardi-Goutières Syndrome and Systemic Lupus Erythematosus (SLE) in a 12-Year-Old Boy With SAMHD1 Mutations

(2011) Georgia Ramantani et al.   JOURNAL OF CHILD NEUROLOGY

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Calcium/Calmodulin-Dependent Protein Kinase Type IV Is Essential for Mesangial Cell Proliferation and Lupus Nephritis

(2011) K. Ichinose et al.   JOURNAL OF IMMUNOLOGY

Intracellular Nucleic Acid Sensors and Autoimmunity

(2011) Argyrios N. Theofilopoulos et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

(2011) Sandra V Navarra et al.   LANCET

Clinical presentations and molecular basis of complement C1r deficiency in a male African–American patient with systemic lupus erythematosus

(2011) YL Wu et al.   LUPUS

IL-17-producing T cells in lupus nephritis

(2011) SA Apostolidis et al.   LUPUS

Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature

(2011) Tracy A Briggs et al.   NATURE GENETICS

Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus

(2011) Sulaiman M Al-Mayouf et al.   NATURE GENETICS

After half-century's wait, approval paves path for new lupus drugs

(2011) Heidi Ledford   NATURE MEDICINE

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

BAFF and selection of autoreactive B cells

(2011) Zheng Liu et al.   TRENDS IN IMMUNOLOGY

CRP/anti-CRP Antibodies Assembly on the Surfaces of Cell Remnants Switches Their Phagocytic Clearance Toward Inflammation

(2011) Christina Janko et al.   Frontiers in Immunology

Interferon-α accelerates murine systemic lupus erythematosus in a T cell-dependent manner

(2010) Zheng Liu et al.   ARTHRITIS AND RHEUMATISM

Suppression of autoimmunity and organ pathology in lupus-prone mice upon inhibition of calcium/calmodulin-dependent protein kinase type IV

(2010) Kunihiro Ichinose et al.   ARTHRITIS AND RHEUMATISM

Elevated levels of soluble CD 14 in serum of patients with systemic lupus erythematosus

(2010) W. A. NOCKHER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Estrogen Receptors in Immunity and Autoimmunity

(2010) Melissa Cunningham et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

C5a alters blood-brain barrier integrity in experimental lupus

(2010) Alexander Jacob et al.   FASEB JOURNAL

Abnormalities of B cell subsets in patients with systemic lupus erythematosus

(2010) Thomas Dörner et al.   JOURNAL OF IMMUNOLOGICAL METHODS

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

(2010) W. Pan et al.   JOURNAL OF IMMUNOLOGY

Inhibition of C5a receptor alleviates experimental CNS lupus

(2010) Alexander Jacob et al.   JOURNAL OF NEUROIMMUNOLOGY

A systemic lupus erythematosus gene expression array in disease diagnosis and classification: a preliminary report

(2010) Y-T Juang et al.   LUPUS

Basophils and the T helper 2 environment can promote the development of lupus nephritis

(2010) Nicolas Charles et al.   NATURE MEDICINE

Cost-of-illness studies in systemic lupus erythematosus: A systematic review

(2010) Tracy Y. Zhu et al.   ARTHRITIS CARE & RESEARCH

Viral RNA Induces Type I Interferon-Dependent Cytokine Release and Cell Death in Mesangial Cells via Melanoma-Differentiation-Associated Gene-5

(2009) Katharina Flür et al.   AMERICAN JOURNAL OF PATHOLOGY

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

(2009) Nicholas Simpson et al.   ARTHRITIS AND RHEUMATISM

Prolidase deficiency: it looks like systemic lupus erythematosus but it is not

(2009) Aharon Klar et al.   EUROPEAN JOURNAL OF PEDIATRICS

Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes

(2009) Z Zhang et al.   GENES AND IMMUNITY

Lyn Kinase Controls Basophil GATA-3 Transcription Factor Expression and Induction of Th2 Cell Differentiation

(2009) Nicolas Charles et al.   IMMUNITY

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway

(2009) Alexander Espinosa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human TCR-  + CD4- CD8- T Cells Can Derive from CD8+ T Cells and Display an Inflammatory Effector Phenotype

(2009) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

Activation of Mammalian Target of Rapamycin Controls the Loss of TCR  in Lupus T Cells through HRES-1/Rab4-Regulated Lysosomal Degradation

(2009) D. R. Fernandez et al.   JOURNAL OF IMMUNOLOGY

High Ro52 Expression in Spontaneous and UV-Induced Cutaneous Inflammation

(2009) Vilija Oke et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies

(2009) Isaac T. W. Harley et al.   NATURE REVIEWS GENETICS

Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus

(2008) Dong Wang et al.   ARTHRITIS AND RHEUMATISM

Requirement of toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis

(2008) Emina Savarese et al.   ARTHRITIS AND RHEUMATISM

The putative protective role of hepatitis B virus (HBV) infection from autoimmune disorders

(2008) Maya Ram et al.   AUTOIMMUNITY REVIEWS

Systemic IFN‐α drives kidney nephritis in B6.Sle123mice

(2008) Anna‐Marie Fairhurst et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients

(2008) A H Sawalha et al.   GENES AND IMMUNITY

Chronic granulomatous disease as a risk factor for autoimmune disease

(2008) Suk See De Ravin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Systemic lupus erythematosus patients have increased number of circulating plasmacytoid dendritic cells, but decreased myeloid dendritic cells with deficient CD83 expression

(2008) Ou Jin et al.   LUPUS

Let Me Count the Ways: Mechanisms of Gene Regulation by miRNAs and siRNAs

(2008) Ligang Wu et al.   MOLECULAR CELL

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

(2008) Anna Yarilina et al.   NATURE IMMUNOLOGY

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors

(2008) B. Mietzner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active systemic lupus erythematosus is associated with failure of antigen-presenting cells to express programmed death ligand-1

(2008) N. Mozaffarian et al.   RHEUMATOLOGY

Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients

(2008) Yong Dai et al.   RHEUMATOLOGY INTERNATIONAL