Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+regulatory T cell development via the CD27–CD70 pathway

CD27 Instructs CD4+ T Cells to Provide Help for the Memory CD8+ T Cell Response after Protein Immunization

(2014) Y. Xiao et al.   JOURNAL OF IMMUNOLOGY

CD27 Signaling Increases the Frequency of Regulatory T Cells and Promotes Tumor Growth

(2012) C. Claus et al.   CANCER RESEARCH

The CD27 and CD70 Costimulatory Pathway Inhibits Effector Function of T Helper 17 Cells and Attenuates Associated Autoimmunity

(2012) Jonathan M. Coquet et al.   IMMUNITY

Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

(2011) Yu Lei et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transforming Growth Factor-β Signaling Curbs Thymic Negative Selection Promoting Regulatory T Cell Development

(2010) Weiming Ouyang et al.   IMMUNITY

Foxp3 induction in human and murine thymus precedes the CD4+ CD8+ stage but requires early T-cell receptor expression

(2010) Helena Nunes-Cabaço et al.   IMMUNOLOGY AND CELL BIOLOGY

CD28 Facilitates the Generation of Foxp3- Cytokine Responsive Regulatory T Cell Precursors

(2010) C. W. J. Lio et al.   JOURNAL OF IMMUNOLOGY

The Pim Kinase Pathway Contributes to Survival Signaling in Primed CD8+ T Cells upon CD27 Costimulation

(2010) V. Peperzak et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: CD28 and c-Rel-Dependent Pathways Initiate Regulatory T Cell Development

(2010) K. B. Vang et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Hematopoietic-Derived APCs Select Regulatory T Cells in Thymus

(2010) E. Roman et al.   JOURNAL OF IMMUNOLOGY

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Selective Expression of the Chemokine Receptor XCR1 on Cross-presenting Dendritic Cells Determines Cooperation with CD8+ T Cells

(2009) Brigitte G. Dorner et al.   IMMUNITY

Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

(2009) Ethan M. Shevach   IMMUNITY

Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology

(2009) Martijn A. Nolte et al.   IMMUNOLOGICAL REVIEWS

CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production

(2009) Victor Peperzak et al.   JOURNAL OF CLINICAL INVESTIGATION

Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus

(2009) JiChu Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets

(2009) Julie C Ribot et al.   NATURE IMMUNOLOGY

Intraclonal competition limits the fate determination of regulatory T cells in the thymus

(2009) Jhoanne L Bautista et al.   NATURE IMMUNOLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire

(2008) Matthew A. Burchill et al.   IMMUNITY

A Two-Step Process for Thymic Regulatory T Cell Development

(2008) Chan-Wang Joaquim Lio et al.   IMMUNITY

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

(2008) Masashi Yano et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differentiation of regulatory Foxp3+ T cells in the thymic cortex

(2008) A. Liston et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cells in the thymus contribute to T-regulatory cell induction

(2008) A. I. Proietto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Foxp3+ regulatory T cells promiscuously accept thymic signals critical for their development

(2008) P. J. Spence et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA