Enhanced CD8 T Cell Responses through GITR-Mediated Costimulation Resolve Chronic Viral Infection
出版年份 2015 全文链接
标题
Enhanced CD8 T Cell Responses through GITR-Mediated Costimulation Resolve Chronic Viral Infection
作者
关键词
T cells, Cytotoxic T cells, Spleen, B cells, Mouse models, T helper cells, Regulatory T cells, Viral transmission and infection
出版物
PLoS Pathogens
Volume 11, Issue 3, Pages e1004675
出版商
Public Library of Science (PLoS)
发表日期
2015-03-05
DOI
10.1371/journal.ppat.1004675
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular and Transcriptional Basis of CD4+ T Cell Dysfunction during Chronic Infection
- (2014) Alison Crawford et al. IMMUNITY
- Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection
- (2014) Shivani Srivastava et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Anti-GITR Agonist Therapy Intrinsically Enhances CD8 T Cell Responses to Chronic Lymphocytic Choriomeningitis Virus (LCMV), Thereby Circumventing LCMV-Induced Downregulation of Costimulatory GITR Ligand on APC
- (2014) Derek L. Clouthier et al. JOURNAL OF IMMUNOLOGY
- Combined PD-1 blockade and GITR triggering induce a potent antitumor immunity in murine cancer models and synergizes with chemotherapeutic drugs
- (2014) Lei Lu et al. Journal of Translational Medicine
- Modulation of Treg cells/T effector function by GITR signaling is context-dependent
- (2013) Amal Ephrem et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Effector-like CD8+ T Cells in the Memory Population Mediate Potent Protective Immunity
- (2013) Janelle A. Olson et al. IMMUNITY
- Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells
- (2012) Yijun Carrier et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Broadly directed virus-specific CD4+T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence
- (2012) Julian Schulze zur Wiesch et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Depletion of NK Cells Prevents T Cell Exhaustion to Efficiently Control Disseminating Virus Infection
- (2012) K. D. Cook et al. JOURNAL OF IMMUNOLOGY
- Progressive Loss of Memory T Cell Potential and Commitment to Exhaustion during Chronic Viral Infection
- (2012) J. M. Angelosanto et al. JOURNAL OF VIROLOGY
- CD8+T Cells: GITR Matters
- (2012) Simona Ronchetti et al. TheScientificWorldJOURNAL
- OX40 Facilitates Control of a Persistent Virus Infection
- (2012) Tobias Boettler et al. PLoS Pathogens
- Autoimmunity associated with immunotherapy of cancer
- (2011) S. M. Amos et al. BLOOD
- Pharmacological modulation of GITRL/GITR system: therapeutic perspectives
- (2011) Giuseppe Nocentini et al. BRITISH JOURNAL OF PHARMACOLOGY
- Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells
- (2011) Laura M. Fahey et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
- (2011) Charlly Kao et al. NATURE IMMUNOLOGY
- T cell exhaustion
- (2011) E John Wherry NATURE IMMUNOLOGY
- Regulatory T-cell expansion during chronic viral infection is dependent on endogenous retroviral superantigens
- (2011) George A. Punkosdy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity
- (2011) P. A. Lang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translating insights from persistent LCMV infection into anti-HIV immunity
- (2010) Elizabeth B. Wilson et al. IMMUNOLOGIC RESEARCH
- PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice
- (2010) Scott N. Mueller et al. JOURNAL OF CLINICAL INVESTIGATION
- CD8 T Cell-Intrinsic GITR Is Required for T Cell Clonal Expansion and Mouse Survival following Severe Influenza Infection
- (2010) L. M. Snell et al. JOURNAL OF IMMUNOLOGY
- Stimulation of the Glucocorticoid-Induced TNF Receptor Family-Related Receptor on CD8 T Cells Induces Protective and High-Avidity T Cell Responses to Tumor-Specific Antigens
- (2010) A. L. Cote et al. JOURNAL OF IMMUNOLOGY
- Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology
- (2009) Martijn A. Nolte et al. IMMUNOLOGICAL REVIEWS
- GITR Triggering Induces Expansion of Both Effector and Regulatory CD4+ T Cells In Vivo
- (2009) R. W. van Olffen et al. JOURNAL OF IMMUNOLOGY
- Tissue-Specific Differences in PD-1 and PD-L1 Expression during Chronic Viral Infection: Implications for CD8 T-Cell Exhaustion
- (2009) S. D. Blackburn et al. JOURNAL OF VIROLOGY
- High antigen levels are the cause of T cell exhaustion during chronic viral infection
- (2009) S. N. Mueller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation
- (2009) R. J. Johnston et al. SCIENCE
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