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Title
Tracing PAKs from GI inflammation to cancer
Authors
Keywords
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Journal
GUT
Volume 63, Issue 7, Pages 1173-1184
Publisher
BMJ
Online
2014-05-09
DOI
10.1136/gutjnl-2014-306768
References
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Note: Only part of the references are listed.- Tu1674 PAK1 Mediates NF-KB Signaling in Colitis and Colitis-Associated Cancer
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- (2014) Xueqiong Fu et al. BIOSCIENCE REPORTS
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- (2014) Hee Kyung Ahn et al. Translational Oncology
- p-21-Activated kinase 1 mediates gastrin-stimulated proliferation in the colorectal mucosa via multiple signaling pathways
- (2013) Nhi Huynh et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Molecular Basis of NF-κB Signaling
- (2013) Johanna Napetschnig et al. Annual Review of Biophysics
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- (2013) Yong Xu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2013) Kevin H. Liu et al. CANCER LETTERS
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- (2013) Kevin B. Myant et al. Cell Stem Cell
- Helicobacter pylori in Gastric Carcinogenesis
- (2013) Lydia E. Wroblewski et al. GASTROENTEROLOGY CLINICS OF NORTH AMERICA
- p21-Activated Kinase 1 (PAK1) Can Promote ERK Activation in a Kinase-independent Manner
- (2013) Zhipeng Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein kinase CK2 phosphorylates and activates p21-activated kinase 1
- (2013) Yong Jae Shin et al. MOLECULAR BIOLOGY OF THE CELL
- Klotho Endows Hepatoma Cells with Resistance to Anoikis via VEGFR2/PAK1 Activation in Hepatocellular Carcinoma
- (2013) Lin Chen et al. PLoS One
- IPA-3 Inhibits the Growth of Liver Cancer Cells By Suppressing PAK1 and NF-κB Activation
- (2013) Leo Lap-Yan Wong et al. PLoS One
- The Pak4 protein kinase is required for oncogenic transformation of MDA-MB-231 breast cancer cells
- (2013) L E Wong et al. Oncogenesis
- Enteropathogenic E. coli effectors EspG1/G2 disrupt tight junctions: new roles and mechanisms
- (2012) Lila G. Glotfelty et al. Annals of the New York Academy of Sciences
- Phosphorylation of β-catenin at serine 663 regulates its transcriptional activity
- (2012) Mee-Hee Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2012) Zhigang Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2012) Vineeta Khare et al. BIOCHEMICAL PHARMACOLOGY
- Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells
- (2012) Shuchen Gu et al. CELLULAR SIGNALLING
- Molecular Pathways: Targeting P21-Activated Kinase 1 Signaling in Cancer--Opportunities, Challenges, and Limitations
- (2012) J. Eswaran et al. CLINICAL CANCER RESEARCH
- Group I and II mammalian PAKs have different modes of activation by Cdc42
- (2012) Yohendran Baskaran et al. EMBO REPORTS
- A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells
- (2012) Karl Staser et al. EXPERIMENTAL HEMATOLOGY
- Hepatitis B Virus X Protein Confers Resistance of Hepatoma Cells to Anoikis by Up-regulating and Activating p21-Activated Kinase 1
- (2012) Jiejie Xu et al. GASTROENTEROLOGY
- Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis
- (2012) Pradeep S. Tanwar et al. HUMAN MOLECULAR GENETICS
- Knockdown of PAK4 or PAK1 Inhibits the Proliferation of Mutant KRAS Colon Cancer Cells Independently of RAF/MEK/ERK and PI3K/AKT Signaling
- (2012) H. Tabusa et al. MOLECULAR CANCER RESEARCH
- Ensembl 2013
- (2012) Paul Flicek et al. NUCLEIC ACIDS RESEARCH
- Inhibition of p21 Activated Kinase (PAK) Reduces Airway Responsiveness In Vivo and In Vitro in Murine and Human Airways
- (2012) Wyn C. Hoover et al. PLoS One
- PAK1 Kinase Promotes Cell Motility and Invasiveness through CRK-II Serine Phosphorylation in Non-Small Cell Lung Cancer Cells
- (2012) Matthew Rettig et al. PLoS One
- Role of p21-activated kinase 1 in regulating the migration and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients
- (2012) D. Fu et al. RHEUMATOLOGY
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- (2012) Haitao Qing et al. TUMOR BIOLOGY
- Wnt Signaling, Stem Cells, and Cancer of the Gastrointestinal Tract
- (2012) A. Schepers et al. Cold Spring Harbor Perspectives in Biology
- Correlations of P21-activated kinase 1 expression to clinicopathological features of gastric carcinoma and patients' prognosis
- (2012) Juan-Xia Wang et al. Chinese Journal of Cancer
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- (2012) Nan Lang et al. Chinese Journal of Cancer
- Molecular Genetics of Colorectal Cancer
- (2011) Eric R. Fearon Annual Review of Pathology-Mechanisms of Disease
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- (2011) Yan Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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- (2011) Hong He et al. CANCER LETTERS
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- (2010) Rana Al-Sadi et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2010) Chunling Yi et al. BIOCHEMICAL PHARMACOLOGY
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- Global Patterns of Cancer Incidence and Mortality Rates and Trends
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- (2010) Motohisa Tada et al. CANCER SCIENCE
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- (2010) Samantha K McCarty et al. ENDOCRINE-RELATED CANCER
- Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations
- (2010) Sumit Bhattacharyya et al. EXPERIMENTAL CELL RESEARCH
- PAK1 as a therapeutic target
- (2010) Julia V Kichina et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Increased expression of p21-activated kinase in adenomyosis
- (2010) So Ra Kim et al. FERTILITY AND STERILITY
- A FOXO-Pak1 transcriptional pathway controls neuronal polarity
- (2010) L. de la Torre-Ubieta et al. GENES & DEVELOPMENT
- LKB1 Suppresses p21-activated Kinase-1 (PAK1) by Phosphorylation of Thr109in the p21-binding Domain
- (2010) Atsuko Deguchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PAK4: a pluripotent kinase that regulates prostate cancer cell adhesion
- (2010) C. M. Wells et al. JOURNAL OF CELL SCIENCE
- N-terminal interaction domain implicates PAK4 in translational regulation and reveals novel cellular localization signals
- (2010) Simona Baldassa et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Colorectal cancer
- (2010) David Cunningham et al. LANCET
- Cadherins and Pak1 Control Contact Inhibition of Proliferation by Pak1- PIX-GIT Complex-Dependent Regulation of Cell-Matrix Signaling
- (2010) F. Liu et al. MOLECULAR AND CELLULAR BIOLOGY
- Integrin-mediated Cell Attachment Induces a PAK4-dependent Feedback Loop Regulating Cell Adhesion through Modified Integrin αvβ5 Clustering and Turnover
- (2010) Zhilun Li et al. MOLECULAR BIOLOGY OF THE CELL
- Phosphoinositides Are Essential Coactivators for p21-Activated Kinase 1
- (2010) Todd I. Strochlic et al. MOLECULAR CELL
- The assembly of a GTPase–kinase signalling complex by a bacterial catalytic scaffold
- (2010) Andrey S. Selyunin et al. NATURE
- Homeobox gene IRX1 is a tumor suppressor gene in gastric carcinoma
- (2010) X Guo et al. ONCOGENE
- Connection between inflammation and carcinogenesis in gastrointestinal tract: Focus on TGF-β signaling
- (2010) Suntaek Hong WORLD JOURNAL OF GASTROENTEROLOGY
- p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics
- (2009) J. D. Allen et al. BLOOD
- P21-activated kinase 5 is overexpressed during colorectal cancer progression and regulates colorectal carcinoma cell adhesion and migration
- (2009) Wei Gong et al. INTERNATIONAL JOURNAL OF CANCER
- Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1
- (2009) Funan Liu et al. INTERNATIONAL JOURNAL OF CANCER
- Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines
- (2009) Kathryn Balmanno et al. INTERNATIONAL JOURNAL OF CANCER
- Pak4, a Novel Gab1 Binding Partner, Modulates Cell Migration and Invasion by the Met Receptor
- (2009) G. N. Paliouras et al. MOLECULAR AND CELLULAR BIOLOGY
- Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
- (2009) Jeffrey C Barrett et al. NATURE GENETICS
- Interaction with LC8 Is Required for Pak1 Nuclear Import and Is Indispensable for Zebrafish Development
- (2009) Christine M. Lightcap et al. PLoS One
- TheDrosophilap21-activated kinase Mbt modulates DE-cadherin-mediated cell adhesion by phosphorylation of Armadillo
- (2008) Nicolas Menzel et al. BIOCHEMICAL JOURNAL
- PAK1 interacts with β-catenin and is required for the regulation of the β-catenin signalling pathway by gastrins
- (2008) Hong He et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- A tale of two Paks
- (2008) Luis E. Arias-Romero et al. BIOLOGY OF THE CELL
- Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells
- (2008) A. S. McDaniel et al. BLOOD
- Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling
- (2008) Ximei Wu et al. CELL
- Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells
- (2008) C Campregher et al. GUT
- Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes
- (2008) Jasna Maksimoska et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Crypt stem cells as the cells-of-origin of intestinal cancer
- (2008) Nick Barker et al. NATURE
- Scaffolding function of PAK in the PDK1–Akt pathway
- (2008) Maiko Higuchi et al. NATURE CELL BIOLOGY
- miR-29 miRNAs activate p53 by targeting p85α and CDC42
- (2008) Seong-Yeon Park et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Involvement of G proteins of the Rho family in the regulation of Bcl-2-like protein expression and caspase 3 activation by Gastrins
- (2007) Hong He et al. CELLULAR SIGNALLING
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