Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis

Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity

(2012) J. I. Partanen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NR5A1 is required for functional maturation of Sertoli cells during postnatal development

(2012) Tomoko Kato et al.   REPRODUCTION

Testicular cancer and the tuberous sclerosis complex

(2011) Torgrim Tandstad et al.   ACTA ONCOLOGICA

Sertoli Cell-Specific Deletion of the Androgen Receptor Compromises Testicular Immune Privilege in Mice1

(2011) Jing Meng et al.   BIOLOGY OF REPRODUCTION

Deletion of Tuberous Sclerosis 1 in Somatic Cells of the Murine Reproductive Tract Causes Female Infertility

(2011) Yoshihiro Tanaka et al.   ENDOCRINOLOGY

LKB1 loss of function studied in vivo

(2011) Boris Y. Shorning et al.   FEBS LETTERS

Adenomatous Polyposis Coli (APC) Is Essential for Maintaining the Integrity of the Seminiferous Epithelium

(2011) Pradeep S. Tanwar et al.   MOLECULAR ENDOCRINOLOGY

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

LKB1 Is an Essential Regulator of Spermatozoa Release during Spermiation in the Mammalian Testis

(2011) Fiona C. Denison et al.   PLoS One

AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress

(2011) T. Williams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The tumor suppressor kinase LKB1: lessons from mouse models

(2011) S. Ollila et al.   Journal of Molecular Cell Biology

Integrative Genomic and Proteomic Analyses Identify Targets for Lkb1-Deficient Metastatic Lung Tumors

(2010) Julian Carretero et al.   CANCER CELL

LKB1 Suppresses p21-activated Kinase-1 (PAK1) by Phosphorylation of Thr109in the p21-binding Domain

(2010) Atsuko Deguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GATA4 regulates Sertoli cell function and fertility in adult male mice☆

(2010) Antti Kyrönlahti et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Regulation of Sertoli-Germ Cell Adhesion and Sperm Release by FSH and Nonclassical Testosterone Signaling

(2010) John Shupe et al.   MOLECULAR ENDOCRINOLOGY

Primary cilia regulate mTORC1 activity and cell size through Lkb1

(2010) Christopher Boehlke et al.   NATURE CELL BIOLOGY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sertoli-germ cell junctions in the testis: a review of recent data

(2010) I. A. Kopera et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Focal Mullerian duct retention in male mice with constitutively activated  -catenin expression in the Mullerian duct mesenchyme

(2010) P. S. Tanwar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive WNT/Beta-Catenin Signaling in Murine Sertoli Cells Disrupts Their Differentiation and Ability to Support Spermatogenesis1

(2009) Pradeep S. Tanwar et al.   BIOLOGY OF REPRODUCTION

Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis

(2009) Cleo S. Bonnet et al.   HUMAN MOLECULAR GENETICS

Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1

(2009) Jing Zhou et al.   HUMAN MOLECULAR GENETICS

Regulation of spermatogenesis in the microenvironment of the seminiferous epithelium: New insights and advances

(2009) C. Yan Cheng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Focal adhesion kinase is a blood-testis barrier regulator

(2009) E. R. Siu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitogen-activated protein kinases in male reproductive function

(2009) Michelle W.M. Li et al.   TRENDS IN MOLECULAR MEDICINE

Regulation of Spermatogonial Stem Cell Self-Renewal in Mammals

(2008) Jon M. Oatley et al.   Annual Review of Cell and Developmental Biology

A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis

(2008) Mhairi C. Towler et al.   BIOCHEMICAL JOURNAL

Seminiferous Tubule Degeneration and Infertility in Mice with Sustained Activation of WNT/CTNNB1 Signaling in Sertoli Cells1

(2008) Alexandre Boyer et al.   BIOLOGY OF REPRODUCTION

Tuberous sclerosis complex proteins control axon formation

(2008) Y.-J. Choi et al.   GENES & DEVELOPMENT

A mesenchymal perspective of müllerian duct differentiation and regression inAmhr2-lacZ mice

(2008) Nelson A. Arango et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

LKB1; linking cell structure and tumor suppression

(2008) A F Hezel et al.   ONCOGENE