A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells

The emerging importance of group II PAKs

(2010) Claire M. Wells et al.   BIOCHEMICAL JOURNAL

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways

(2010) Nhi Huynh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Xenopus Skip Modulates Wnt/β-Catenin Signaling and Functions in Neural Crest Induction

(2010) Ying Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo

(2010) Z Wang et al.   ONCOGENE

Pak protein kinases and their role in cancer

(2009) Bettina Dummler et al.   CANCER AND METASTASIS REVIEWS

A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss

(2009) Reid A. Phelps et al.   CELL

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

β-Catenin hits chromatin: regulation of Wnt target gene activation

(2009) Christian Mosimann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

P-21-activated protein kinase-1 functions as a linker between insulin and Wnt signaling pathways in the intestine

(2009) J Sun et al.   ONCOGENE

PAK signaling in oncogenesis

(2009) P R Molli et al.   ONCOGENE

PAK1 interacts with β-catenin and is required for the regulation of the β-catenin signalling pathway by gastrins

(2008) Hong He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A tale of two Paks

(2008) Luis E. Arias-Romero et al.   BIOLOGY OF THE CELL

Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling

(2008) Ximei Wu et al.   CELL

An Isoform-Selective, Small-Molecule Inhibitor Targets the Autoregulatory Mechanism of p21-Activated Kinase

(2008) Sean W. Deacon et al.   CHEMISTRY & BIOLOGY

Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations

(2008) Stefania Segditsas et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Plasma membrane recruitment of dephosphorylated  -catenin upon activation of the Wnt pathway

(2008) J. Hendriksen et al.   JOURNAL OF CELL SCIENCE

G o mediates WNT-JNK signaling through Dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells

(2008) R. K. Bikkavilli et al.   JOURNAL OF CELL SCIENCE