Drug-induced liver injury: a safety review

Drug induced liver injury with analysis of alternative causes as confounding variables

(2018) Rolf Teschke et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort

(2018) Rachel J. Church et al.   HEPATOLOGY

Expanding our toolkit to better identify drug-induced liver injury in electronic medical records

(2018) Christine M. Hunt   LIVER INTERNATIONAL

Safety data and withdrawal of hepatotoxic drugs

(2018) Samy Babai et al.   THERAPIE

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

(2017) Paola Nicoletti et al.   GASTROENTEROLOGY

Drug-induced liver injury: recent advances in diagnosis and risk assessment

(2017) Gerd A Kullak-Ublick et al.   GUT

Death and liver transplantation within 2 years of onset of drug-induced liver injury

(2017) Paul H. Hayashi et al.   HEPATOLOGY

Systematic review and meta-analysis of algorithms used to identify drug-induced liver injury (DILI) in health record databases

(2017) Eng Hooi Tan et al.   LIVER INTERNATIONAL

Histopathological challenges in suspected drug-induced liver injury

(2017) David E. Kleiner   LIVER INTERNATIONAL

Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery

(2017) Valentina Peta et al.   PLoS One

Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human

(2017) Julian Krauskopf et al.   PLoS One

Drug-Induced Liver Injury: Pattern Recognition and Future Directions

(2016) Tanvir Haque et al.   Gut and Liver

Definition and risk factors for chronicity following acute idiosyncratic drug-induced liver injury

(2016) Inmaculada Medina-Caliz et al.   JOURNAL OF HEPATOLOGY

Pro-Euro-Dili Registry: A Collaborative Effort to Enhance the Understanding of Dili

(2016) M. Slim et al.   JOURNAL OF HEPATOLOGY

Chronic hepatitis B infection and risk of antituberculosis drug-induced liver injury: Systematic review and meta-analysis

(2016) Ning-Tao Wang et al.   Journal of the Chinese Medical Association

Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study

(2015) Naga Chalasani et al.   GASTROENTEROLOGY

Drug-induced liver injury: Interactions between drug properties and host factors

(2015) Minjun Chen et al.   JOURNAL OF HEPATOLOGY

Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications

(2015) Lily Dara et al.   LIVER INTERNATIONAL

Pharmacogenetic testing in idiosyncratic drug-induced liver injury: current role in clinical practice

(2015) Guruprasad P. Aithal   LIVER INTERNATIONAL

End-stage methotrexate-related liver disease is rare and associated with features of the metabolic syndrome

(2014) M. F. Dawwas et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Liver Safety Assessment in Special Populations (Hepatitis B, C, and Oncology Trials)

(2014) Gerd A. Kullak-Ublick et al.   DRUG SAFETY

Use of Hy's Law and a New Composite Algorithm to Predict Acute Liver Failure in Patients With Drug-Induced Liver Injury

(2014) Mercedes Robles–Diaz et al.   GASTROENTEROLOGY

Idiosyncratic Drug-Induced Liver Injury Is Associated With Substantial Morbidity and Mortality Within 6 Months From Onset

(2014) Robert J. Fontana et al.   GASTROENTEROLOGY

Prospective Validation ofHLA-DRB1*07:01Allele Carriage As a Predictive Risk Factor for Lapatinib-Induced Liver Injury

(2014) Daniel J. Schaid et al.   JOURNAL OF CLINICAL ONCOLOGY

Open TG-GATEs: a large-scale toxicogenomics database

(2014) Yoshinobu Igarashi et al.   NUCLEIC ACIDS RESEARCH

Age-related differences in reporting of drug-associated liver injury: Data-mining of WHO Safety Report Database

(2014) Christine M. Hunt et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Drug-Induced Liver Injury with Autoimmune Features

(2014) David Foureau et al.   SEMINARS IN LIVER DISEASE

The Liver Toxicity Knowledge Base: A Systems Approach to a Complex End Point

(2013) M Chen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Incidence, Presentation, and Outcomes in Patients With Drug-Induced Liver Injury in the General Population of Iceland

(2013) Einar S. Björnsson et al.   GASTROENTEROLOGY

Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital

(2013) Daniel J. Antoine et al.   HEPATOLOGY

Hepatic histological findings in suspected drug-induced liver injury: Systematic evaluation and clinical associations

(2013) David E. Kleiner et al.   HEPATOLOGY

LTMap: a web server for assessing the potential liver toxicity by genome-wide transcriptional expression data

(2013) Li Xing et al.   JOURNAL OF APPLIED TOXICOLOGY

Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts

(2013) Petra Thulin et al.   LIVER INTERNATIONAL

A Prospective Nationwide Study of Drug-Induced Liver Injury in Korea

(2012) Ki Tae Suk et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

LiverTox: A website on drug-induced liver injury

(2012) Jay H. Hoofnagle et al.   HEPATOLOGY

Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

(2012) Daniel J. Antoine et al.   JOURNAL OF HEPATOLOGY

A Performance Evaluation of Three Drug-Induced Liver Injury Biomarkers in the Rat: Alpha-Glutathione S-Transferase, Arginase 1, and 4-Hydroxyphenyl-Pyruvate Dioxygenase

(2012) Wendy J. Bailey et al.   TOXICOLOGICAL SCIENCES

In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers

(2012) Ana Alfirevic et al.   Genome Medicine

Case Definition and Phenotype Standardization in Drug-Induced Liver Injury

(2011) G P Aithal et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A generic operational strategy to qualify translational safety biomarkers

(2011) Katja Matheis et al.   DRUG DISCOVERY TODAY

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

Causality assessment methods in drug induced liver injury: Strengths and weaknesses

(2011) Miren García-Cortés et al.   JOURNAL OF HEPATOLOGY

Mechanisms of drug-induced liver injury: from bedside to bench

(2011) Shannan Tujios et al.   Nature Reviews Gastroenterology & Hepatology

Evaluation of Naranjo Adverse Drug Reactions Probability Scale in causality assessment of drug-induced liver injury

(2010) M. GARCÍA-CORTÉS et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug-induced liver injury

(2010) M. Isabel Lucena et al.   HEPATOLOGY

Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study

(2010) Adrian Reuben et al.   HEPATOLOGY

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Interference with Bile Salt Export Pump Function Is a Susceptibility Factor for Human Liver Injury in Drug Development

(2010) Ryan E. Morgan et al.   TOXICOLOGICAL SCIENCES

Drug-Induced Liver Injury Network (DILIN) Prospective Study

(2009) Robert J. Fontana et al.   DRUG SAFETY

Rechallenge in drug-induced liver injury: the attractive hazard

(2009) Raúl J Andrade et al.   Expert Opinion On Drug Safety

Phenotypic characterization of idiosyncratic drug-induced liver injury: The influence of age and sex

(2009) M. Isabel Lucena et al.   HEPATOLOGY

Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events

(2009) Craig Lammert et al.   HEPATOLOGY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Drug-induced liver injury: insights from genetic studies

(2009) Raúl J Andrade et al.   PHARMACOGENOMICS

Circulating microRNAs, potential biomarkers for drug-induced liver injury

(2009) K. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

(2009) Daniel J. Antoine et al.   TOXICOLOGICAL SCIENCES

GlutathioneS-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury

(2008) M. Isabel Lucena et al.   HEPATOLOGY

Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: Search for signals

(2008) Craig Lammert et al.   HEPATOLOGY

The long-term follow-up after idiosyncratic drug-induced liver injury with jaundice

(2008) Einar Björnsson et al.   JOURNAL OF HEPATOLOGY

Antituberculosis drug-induced hepatotoxicity: Concise up-to-date review

(2007) Alma Tostmann et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY