Interference with Bile Salt Export Pump Function Is a Susceptibility Factor for Human Liver Injury in Drug Development

Application of Genomics for Identification of Systemic Toxicity Triggers Associated With VEGF-R Inhibitors

(2010) Hisham K. Hamadeh et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Hepatotoxicity and hepatic metabolism of available drugs: current problems and possible solutions in preclinical stages

(2010) Shibashish Giri et al.   Expert Opinion on Drug Metabolism & Toxicology

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

(2010) C. D. Klaassen et al.   PHARMACOLOGICAL REVIEWS

Technical Pitfalls and Improvements for High-speed Screening and QSAR Analysis to Predict Inhibitors of the Human Bile Salt Export Pump (ABCB11/BSEP)

(2009) Hikaru Saito et al.   AAPS Journal

Compensatory role of P-glycoproteins in knockout mice lacking the bile salt export pump

(2009) Renxue Wang et al.   HEPATOLOGY

De novo bile salt transporter antibodies as a possible cause of recurrent graft failure after liver transplantation: A novel mechanism of cholestasis

(2009) Verena Keitel et al.   HEPATOLOGY

Histological patterns in drug-induced liver disease

(2009) R Ramachandran et al.   JOURNAL OF CLINICAL PATHOLOGY

Bile acid transporters

(2009) Paul A. Dawson et al.   JOURNAL OF LIPID RESEARCH

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Update on Progressive Familial Intrahepatic Cholestasis

(2009) Feras T Alissa et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Recurrence of Bile Salt Export Pump Deficiency after Liver Transplantation

(2009) Paloma Jara et al.   NEW ENGLAND JOURNAL OF MEDICINE

Progressive familial intrahepatic cholestasis

(2009) Anne Davit-Spraul et al.   Orphanet Journal of Rare Diseases

Role of Hepatic Transporters in the Disposition and Hepatotoxicity of a HER2 Tyrosine Kinase Inhibitor CP-724,714

(2009) Bo Feng et al.   TOXICOLOGICAL SCIENCES

Mechanisms of Cholestasis

(2008) Gernot Zollner et al.   Clinics in Liver Disease

Species-Specific and Age-Dependent Bile Acid Composition: Aspects on CYP8B and CYP4A Subfamilies in Bile Acid Biosynthesis

(2008) Kerstin Lundell et al.   CURRENT DRUG METABOLISM

Mitochondrial dysfunction and delayed hepatotoxicity: another lesson from troglitazone

(2008) N. L. Julie et al.   DIABETOLOGIA

Severe Bile Salt Export Pump Deficiency: 82 Different ABCB11 Mutations in 109 Families

(2008) Sandra S. Strautnieks et al.   GASTROENTEROLOGY

Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy

(2008) P H Dixon et al.   GUT

Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing

(2008) Jane A. Byrne et al.   HEPATOLOGY