Pharmacogenetic testing in idiosyncratic drug-induced liver injury: current role in clinical practice

Human Leukocyte Antigen (HLA) Pharmacogenomic Tests: Potential and Pitfalls

(2014) Ann Daly   CURRENT DRUG METABOLISM

N-acetyltransferase 2 (NAT2) genotype as a risk factor for development of drug-induced liver injury relating to antituberculosis drug treatment in a mixed-ethnicity patient group

(2014) Ching-Soon Ng et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Prospective Validation ofHLA-DRB1*07:01Allele Carriage As a Predictive Risk Factor for Lapatinib-Induced Liver Injury

(2014) Daniel J. Schaid et al.   JOURNAL OF CLINICAL ONCOLOGY

HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

(2014) Graham A Heap et al.   NATURE GENETICS

Genetic Basis of Drug-Induced Liver Injury: Present and Future

(2014) Thomas Urban et al.   SEMINARS IN LIVER DISEASE

Incidence, Presentation, and Outcomes in Patients With Drug-Induced Liver Injury in the General Population of Iceland

(2013) Einar S. Björnsson et al.   GASTROENTEROLOGY

HLA-B*5801: utility and cost-effectiveness in the Asia-Pacific Region

(2013) Siaw Ing Yeo   International Journal of Rheumatic Diseases

Associations Between HLA-DRB1*0102, HLA-B*5801, and Hepatotoxicity During Initiation of Nevirapine-Containing Regimens in South Africa

(2013) Elizabeth Phillips et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Hepatotoxicity from anabolic androgenic steroids marketed as dietary supplements: contribution fromATP8B1/ABCB11mutations?

(2013) Yasser El Sherrif et al.   LIVER INTERNATIONAL

HLA-B*13:01 and the Dapsone Hypersensitivity Syndrome

(2013) F.-R. Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

HLA Alleles Influence the Clinical Signature of Amoxicillin-Clavulanate Hepatotoxicity

(2013) Camilla Stephens et al.   PLoS One

Relationship Between theHLA-B*1502Allele and Carbamazepine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

(2013) Wimonchat Tangamornsuksan et al.   JAMA Dermatology

Predictive Genetic Testing for Drug-Induced Liver Injury: Considerations of Clinical Utility

(2012) A Alfirevic et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Pharmacogenomic HLA Biomarker Associated to Adverse Abacavir Reactions: Comparative Analysis of Different Genotyping Methods

(2012) Laura Stocchi et al.   CURRENT GENOMICS

NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: A randomized controlled trial for pharmacogenetics-based therapy

(2012) Junichi Azuma et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

HLA and pharmacogenetics of drug hypersensitivity

(2012) Rebecca Pavlos et al.   PHARMACOGENOMICS

Pharmacogenetic Study of Drug-Metabolising Enzyme Polymorphisms on the Risk of Anti-Tuberculosis Drug-Induced Liver Injury: A Meta-Analysis

(2012) Yu Cai et al.   PLoS One

In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers

(2012) Ana Alfirevic et al.   Genome Medicine

Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian, and European descent

(2011) Jing Yuan et al.   AIDS

HLA-Dependent Hypersensitivity Reaction to Nevirapine in Chinese Han HIV-Infected Patients

(2011) Shicheng Gao et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Case Definition and Phenotype Standardization in Drug-Induced Liver Injury

(2011) G P Aithal et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

HLA-DQA1*02:01 Is a Major Risk Factor for Lapatinib-Induced Hepatotoxicity in Women With Advanced Breast Cancer

(2011) Colin F. Spraggs et al.   JOURNAL OF CLINICAL ONCOLOGY

Hepatotoxicity related to antirheumatic drugs

(2011) Guruprasad P. Aithal   Nature Reviews Rheumatology

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury

(2010) Peter T. Donaldson et al.   JOURNAL OF HEPATOLOGY

Preempting and preventing drug-induced liver injury

(2010) Guruprasad P Aithal et al.   NATURE GENETICS

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients

(2009) Soranun Chantarangsu et al.   Pharmacogenetics and Genomics

High Sensitivity of Human Leukocyte Antigen–B*5701 as a Marker for Immunologically Confirmed Abacavir Hypersensitivity in White and Black Patients

(2008) Michael Saag et al.   CLINICAL INFECTIOUS DISEASES

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE