The Role of Phytochemicals in the Treatment and Prevention of Dementia

Cannabinoids and Neurodegenerative Diseases

(2012) Julian Romero et al.   CNS & Neurological Disorders-Drug Targets

Non-Steroidal Anti-Inflammatory Drugs and Alzheimers Disease: The Epidemiological Evidence

(2012) C.A. Szekely et al.   CNS & Neurological Disorders-Drug Targets

A Double-Blind Placebo-Controlled Randomized Trial of Melissa officinalis Oil and Donepezil for the Treatment of Agitation in Alzheimer’s Disease

(2011) Alistair Burns et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells

(2010) Chun Shi et al.   APOPTOSIS

Inflammation and Alzheimer’s disease

(2010) Young-Jung Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Wogonin induces differentiation and neurite outgrowth of neural precursor cells

(2010) Jung Su Lim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rescue of ER oxidoreductase function through polyphenolic phytochemical intervention: Implications for subcellular traffic and neurodegenerative disorders

(2010) Rituraj Pal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Beta-Asarone Improves Cognitive Function by Suppressing Neuronal Apoptosis in the Beta-Amyloid Hippocampus Injection Rats

(2010) Yutao Geng et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Effect of corosolic acid on dietary hypercholesterolemia and hepatic steatosis in KK-Ay diabetic mice

(2010) Satoshi Takagi et al.   BIOMEDICAL RESEARCH-TOKYO

Gentisides C–K: Nine new neuritogenic compounds from the traditional Chinese medicine Gentiana rigescens Franch

(2010) Lijuan Gao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure–activity studies on acetylcholinesterase inhibition in the lycorine series of Amaryllidaceae alkaloids

(2010) James McNulty et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

NGF-potentiating vibsane-type diterpenoids from Viburnum sieboldii

(2010) Miwa Kubo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The impact of fruit flavonoids on memory and cognition

(2010) Jeremy P. E. Spencer   BRITISH JOURNAL OF NUTRITION

Protective Effects of Paeoniflorin Against Glutamate-Induced Neurotoxicity in PC12 Cells via Antioxidant Mechanisms and Ca2+ Antagonism

(2010) Qing-Qiu Mao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Development of an Efficient Therapeutic Agent for Alzheimer's Disease: Design and Synthesis of Dual Inhibitors of Acetylcholinesterase and Serotonin Transporter

(2010) Narihiro Toda et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Decreased cerebral α4β2* nicotinic acetylcholine receptor availability in patients with mild cognitive impairment and Alzheimer’s disease assessed with positron emission tomography

(2010) Kai Kendziorra et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Antidepressant-like effects of neferine in the forced swimming test involve the serotonin1A (5-HT1A) receptor in mice

(2010) Yumi Sugimoto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Tenuigenin protects cultured hippocampal neurons against methylglyoxal-induced neurotoxicity

(2010) Yu-Jing Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells

(2010) Kyong Nyon Nam et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ginkgolide B protects hippocampal neurons from apoptosis induced by beta-amyloid 25–35 partly via up-regulation of brain-derived neurotrophic factor

(2010) Qian Xiao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction

(2010) Ji Hyun Choi et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Effects of galantamine on β-amyloid release and beta-site cleaving enzyme 1 expression in differentiated human neuroblastoma SH-SY5Y cells

(2010) Qianqian Li et al.   EXPERIMENTAL GERONTOLOGY

Puerarin protects Alzheimer's disease neuronal cybrids from oxidant-stress induced apoptosis by inhibiting pro-death signaling pathways

(2010) Haiying Zhang et al.   EXPERIMENTAL GERONTOLOGY

Structural insights to investigate Conypododiol as a dual cholinesterase inhibitor from Asparagus adscendens

(2010) Inamullah Khan et al.   FITOTERAPIA

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

ORIGINAL ARTICLE: Saffron in the treatment of patients with mild to moderate Alzheimer’s disease: a 16-week, randomized and placebo-controlled trial

(2010) S. Akhondzadeh et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Antihypertensive and neuroprotective activities of rhynchophylline: The role of rhynchophylline in neurotransmission and ion channel activity

(2010) Jiyin Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

Protective effects of the pyrolyzates derived from bamboo against neuronal damage and hematoaggregation

(2010) Eui-Ju Hong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Estrogenic and serotonergic butenolides from the leaves of Piper hispidum Swingle (Piperaceae)

(2010) Joanna L. Michel et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-amnesic effect of Chong–Myung–Tang on scopolamine-induced memory impairments in mice

(2010) Mi-Ra Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

New physiological function of secoiridoids: neuritogenic activity in PC12h cells

(2010) Kenzo Chiba et al.   Journal of Natural Medicines

Withanolide A and Asiatic Acid Modulate Multiple Targets Associated with Amyloid-β Precursor Protein Processing and Amyloid-β Protein Clearance

(2010) Sachin P. Patil et al.   JOURNAL OF NATURAL PRODUCTS

Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: Possible role of reactive oxygen species

(2010) Usha Gundimeda et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Pharmacological profile of essential oils derived fromLavandula angustifoliaandMelissa officinaliswith anti-agitation properties: focus on ligand-gated channels

(2010) Liping Huang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Effect of wild ginseng on scopolamine-induced acetylcholine depletion in the rat hippocampus

(2010) Bombi Lee et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Anti-amnesic activity of neferine with antioxidant and anti-inflammatory capacities, as well as inhibition of ChEs and BACE1

(2010) Hyun Ah Jung et al.   LIFE SCIENCES

Natural products as a source of Alzheimer's drug leads

(2010) Philip Williams et al.   NATURAL PRODUCT REPORTS

How does diabetes accelerate Alzheimer disease pathology?

(2010) Catrina Sims-Robinson et al.   Nature Reviews Neurology

Protective effects of galantamine against Aβ-induced PC12 cell apoptosis by preventing mitochondrial dysfunction and endoplasmic reticulum stress

(2010) Xiaoyu Liu et al.   NEUROCHEMISTRY INTERNATIONAL

Apigenin protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis

(2010) A Young Choi et al.   NEUROCHEMISTRY INTERNATIONAL

List of Drugs in Development for Neurodegenerative Diseases: Update June 2010

(2010) Vanda Pogačić Kramp et al.   Neurodegenerative Diseases

The enhancement effect of beta-boswellic acid on hippocampal neurites outgrowth and branching (an in vitro study)

(2010) Oveis Karima et al.   NEUROLOGICAL SCIENCES

Neurotransmitter changes in dementia with Lewy bodies and Parkinson disease dementia in vivo

(2010) J. C. Klein et al.   NEUROLOGY

Icariin attenuates β-amyloid-induced neurotoxicity by inhibition of tau protein hyperphosphorylation in PC12 cells

(2010) Ke-Wu Zeng et al.   NEUROPHARMACOLOGY

Neurochemical basis for symptomatic treatment of Alzheimer's disease

(2010) Paul T. Francis et al.   NEUROPHARMACOLOGY

The neuroprotective effects of tanshinone IIA on β-amyloid-induced toxicity in rat cortical neurons

(2010) Tao Liu et al.   NEUROPHARMACOLOGY

Galantamine inhibits calpain–calcineurin signaling activated by beta-amyloid in human neuroblastoma SH-SY5Y cells

(2010) Qianqian Li et al.   NEUROSCIENCE LETTERS

Use of Yokukansan (TJ-54) in the treatment of neurological disorders: a review

(2010) S. de Caires et al.   PHYTOTHERAPY RESEARCH

Effects of Yokukansan on behavioral and psychological symptoms of dementia in regular treatment for Alzheimer's disease

(2010) Kazunori Okahara et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Treatment of behavioral and psychological symptoms of Alzheimer-type dementia with Yokukansan in clinical practice

(2010) Yoshihito Hayashi et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Effects of Ginkgo biloba in dementia: systematic review and meta-analysis

(2010) Stefan Weinmann et al.   BMC Geriatrics

Tenuifolin, an extract derived fromtenuigenin, inhibits amyloid-β secretionin vitro

(2009) J. Lv et al.   Acta Physiologica

Anti-aging herbal medicine—How and why can they be used in aging-associated neurodegenerative diseases?

(2009) Yuen-Shan Ho et al.   AGEING RESEARCH REVIEWS

Ginkgo bilobaextract EGb 761®, donepezil or both combined in the treatment of Alzheimer's disease with neuropsychiatric features: A randomised, double-blind, exploratory trial

(2009) S. Yancheva et al.   AGING & MENTAL HEALTH

Drug development for Alzheimer's disease: Where are we now and where are we headed?

(2009) Marwan N. Sabbagh   American Journal Geriatric Pharmacotherapy

Piceatannol Attenuates 4-Hydroxynonenal-Induced Apoptosis of PC12 Cells by Blocking Activation of c-Jun N-Terminal Kinase

(2009) Young Jin Jang et al.   Annals of the New York Academy of Sciences

Protective effect of curcumin (Curcuma longa), against aluminium toxicity: Possible behavioral and biochemical alterations in rats

(2009) Anil Kumar et al.   BEHAVIOURAL BRAIN RESEARCH

Berberine Exerts Neuroprotective Actions against in Vitro Ischemia-Induced Neuronal Cell Damage in Organotypic Hippocampal Slice Cultures: Involvement of B-Cell Lymphoma 2 Phosphorylation Suppression

(2009) Hu-Shan Cui et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Anti-Alzheimer and Antioxidant Activities of Coptidis Rhizoma Alkaloids

(2009) Hyun Ah Jung et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mild Cognitive Impairment in the Elderly is Associated with Volume Loss of the Cholinergic Basal Forebrain Region

(2009) Kathrin Muth et al.   BIOLOGICAL PSYCHIATRY

Synthesis and structure–activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors

(2009) Cyril Ronco et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Delphinidin Ameliorates Beta-Amyloid-Induced Neurotoxicity by Inhibiting Calcium Influx and Tau Hyperphosphorylation

(2009) Hyo-Shin KIM et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Silibinin prevents amyloid β peptide-induced memory impairment and oxidative stress in mice

(2009) P Lu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Polysaccharides from Wolfberry Antagonizes Glutamate Excitotoxicity in Rat Cortical Neurons

(2009) Yuen-Shan Ho et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Neuroprotective Effects of Vinpocetine and its Major MetaboliteCis-apovincaminic Acid on NMDA-Induced Neurotoxicity in a Rat Entorhinal Cortex Lesion Model

(2009) Csaba Nyakas et al.   CNS Neuroscience & Therapeutics

Resveratrol and Neurodegenerative Diseases: Activation of SIRT1 as the Potential Pathway towards Neuroprotection

(2009) Merce Pallas et al.   CURRENT NEUROVASCULAR RESEARCH

Update in the epidemiology of Parkinsonʼs disease

(2009) Alexis Elbaz et al.   CURRENT OPINION IN NEUROLOGY

Safety and Tolerability of Donepezil, Rivastigmine and Galantamine for Patients with Alzheimer’s Disease: Systematic Review of the ‘Real-World’ Evidence

(2009) I.A. Lockhart et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

To treat or not to treat? A meta-analysis of the use of cholinesterase inhibitors in mild cognitive impairment for delaying progression to Alzheimer’s disease

(2009) Breno Satler Diniz et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Galantamine protects against oxidative stress induced by amyloid-beta peptide in cortical neurons

(2009) Joana B. Melo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Amelioration of intracerebroventricular streptozotocin induced cognitive dysfunction and oxidative stress by vinpocetine — a PDE1 inhibitor

(2009) Rahul Deshmukh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats

(2009) Jiyin Zhou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A novel compound N1,N5-(Z)-N10-(E)-tri-p-coumaroylspermidine isolated from Carthamus tinctorius L. and acting by serotonin transporter inhibition

(2009) Gang Zhao et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Neurogenesis and Alzheimer's disease: At the crossroads

(2009) Orly Lazarov et al.   EXPERIMENTAL NEUROLOGY

Ginkgo biloba: specificity of neuropsychological improvement-a selective review in search of differential effects

(2009) Reiner Kaschel   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Are cholinesterase inhibitors effective in the management of the behavioral and psychological symptoms of dementia in Alzheimer's disease? A systematic review of randomized, placebo-controlled trials of donepezil, rivastigmine and galantamine

(2009) Joanne Rodda et al.   INTERNATIONAL PSYCHOGERIATRICS

Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells

(2009) Kunio Kosaka et al.   JOURNAL OF BIOCHEMISTRY

Six-Month Randomized, Placebo-Controlled, Double-Blind, Pilot Clinical Trial of Curcumin in Patients With Alzheimer Disease

(2009) Larry Baum et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Isoflavones Prevent Endoplasmic Reticulum Stress-Mediated Neuronal Degeneration by Inhibiting Tau Hyperphosphorylation in SH-SY5Y Cells

(2009) Youn-Jin Park et al.   JOURNAL OF MEDICINAL FOOD

Memogain is a Galantamine Pro-drug having Dramatically Reduced Adverse Effects and Enhanced Efficacy

(2009) Alfred Maelicke et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Ginkgo bilobaand Ginkgotoxin

(2009) Eckhard Leistner et al.   JOURNAL OF NATURAL PRODUCTS

Efficacy and safety of natural acetylcholinesterase inhibitor huperzine A in the treatment of Alzheimer’s disease: an updated meta-analysis

(2009) Bai-song Wang et al.   JOURNAL OF NEURAL TRANSMISSION

Naturally occurring phytochemicals for the prevention of Alzheimer’s disease

(2009) Jiyoung Kim et al.   JOURNAL OF NEUROCHEMISTRY

Galantamine inhibits β-amyloid aggregation and cytotoxicity

(2009) Balpreet Matharu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Protective effect of curcumin against intracerebral streptozotocin induced impairment in memory and cerebral blood flow

(2009) Himani Awasthi et al.   LIFE SCIENCES

Alzheimer's disease: synaptic dysfunction and Aβ

(2009) Ganesh M Shankar et al.   Molecular Neurodegeneration

Amaryllidaceae and Sceletium alkaloids

(2009) Zhong Jin   NATURAL PRODUCT REPORTS

Management of agitation and aggression associated with Alzheimer disease

(2009) Clive G. Ballard et al.   Nature Reviews Neurology

Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation

(2009) Yoshiari Shimmyo et al.   NEUROREPORT

Neuroprotective effects of yokukansan, a traditional japanese medicine, on glutamate-mediated excitotoxicity in cultured cells

(2009) Z. Kawakami et al.   NEUROSCIENCE

Smoking, nicotine and neuropsychiatric disorders

(2009) Peter Dome et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

BT-11 is effective for enhancing cognitive functions in the elderly humans

(2009) Ki Young Shin et al.   NEUROSCIENCE LETTERS

Effects of BT-11 on memory in healthy humans

(2009) Jun-Young Lee et al.   NEUROSCIENCE LETTERS

Anti-inflammatory effects of daidzein on primary astroglial cell culture

(2009) Man-Hai Liu et al.   NUTRITIONAL NEUROSCIENCE

Cytotoxicity ofVinca minor

(2009) Mahnaz Khanavi et al.   PHARMACEUTICAL BIOLOGY

Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat

(2009) Rahul Agrawal et al.   PHARMACOLOGICAL RESEARCH

Inhibitory effect of ethanol extract of Magnolia officinalis and 4-O-methylhonokiol on memory impairment and neuronal toxicity induced by beta-amyloid

(2009) Jae Woong Lee et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Anxiolytic and hypnotic effect ofCrocus sativusaqueous extract and its constituents, crocin and safranal, in mice

(2009) Hossein Hosseinzadeh et al.   PHYTOTHERAPY RESEARCH

Successful treatment with Yokukansan for behavioral and psychological symptoms of Parkinsonian dementia

(2009) Tadaaki Kawanabe et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Increased glutamate in the hippocampus after galantamine treatment for Alzheimer disease

(2009) Jacob Penner et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Five cases of frontotemporal dementia with behavioral symptoms improved by Yokukansan

(2009) Takemi KIMURA et al.   Psychogeriatrics

A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer’s disease

(2009) Shahin Akhondzadeh et al.   PSYCHOPHARMACOLOGY

Alcohol in Moderation, Cardioprotection, and Neuroprotection: Epidemiological Considerations and Mechanistic Studies

(2008) Michael A. Collins et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Panax Ginseng Enhances Cognitive Performance in Alzheimer Disease

(2008) Soon-Tae Lee et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Alzheimer's and Non-Alzheimer's Dementia: A Critical Review of Pharmacological and Nonpharmacological Strategies

(2008) Sahoo Saddichha et al.   American Journal of Alzheimers Disease and Other Dementias

Galantamine for the Treatment of BPSD in Thai Patients With Possible Alzheimer's Disease With or Without Cerebrovascular Disease

(2008) S. Tangwongchai et al.   American Journal of Alzheimers Disease and Other Dementias

β-secretase (BACE1) inhibitors from Perilla frutescens var. acuta

(2008) Sun-Ha Choi et al.   ARCHIVES OF PHARMACAL RESEARCH

Therapeutic potential of resveratrol in Alzheimer's disease

(2008) Valérie Vingtdeux et al.   BMC NEUROSCIENCE

Green tea epigallocatechin-3-gallate (EGCG) reduces β-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice

(2008) Kavon Rezai-Zadeh et al.   BRAIN RESEARCH

Drugs Used to Treat Parkinsons Disease, Present Status and Future Directions

(2008) Omar Abdel-Salam   CNS & Neurological Disorders-Drug Targets

Alzheimer Disease and the Role of Free Radicals in the Pathogenesis of the Disease

(2008) George Perry et al.   CNS & Neurological Disorders-Drug Targets

Resveratrol: A Natural Compound with Pharmacological Potential in Neurodegenerative Diseases

(2008) Héctor I. Rocha-González et al.   CNS Neuroscience & Therapeutics

GuidAge Study: A 5-Year Double Blind, Randomised Trial of EGb 761 for the Prevention of Alzheimers Disease in Elderly Subjects with Memory Complaints. I. Rationale, Design and Baseline Data

(2008) Sandrine Andrieu et al.   Current Alzheimer Research

Natural Products and their Derivatives as Cholinesterase Inhibitors in the Treatment of Neurodegenerative Disorders: An Update

(2008) Monica Loizzo et al.   CURRENT MEDICINAL CHEMISTRY

Acetylcholinesterase Inhibitors as Disease-Modifying Therapies for Alzheimers Disease

(2008) D. Munoz-Torrero   CURRENT MEDICINAL CHEMISTRY

Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience

(2008) Gabor G. Kovacs et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

An open-label trial of Korean red ginseng as an adjuvant treatment for cognitive impairment in patients with Alzheimers disease

(2008) J.-H. Heo et al.   EUROPEAN JOURNAL OF NEUROLOGY

Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: Evidence for the involvement of the serotonergic and noradrenergic systems

(2008) Daniele G. Machado et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Non-cholinergic drug development for Alzheimer's disease

(2008) Roy Yaari et al.   Expert Opinion on Drug Discovery

Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity

(2008) Long Tai Zheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A randomized cross-over study of a traditional Japanese medicine (kampo), yokukansan, in the treatment of the behavioural and psychological symptoms of dementia

(2008) Katsuyoshi Mizukami et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Ginkgo biloba for Prevention of DementiaA Randomized Controlled Trial

(2008) Steven T. DeKosky   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Crystal and Molecular Structure of Piceatannol; Scavenging Features of Resveratrol and Piceatannol on Hydroxyl and Peroxyl Radicals and Docking with Transthyretin

(2008) Miriam Rossi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ameliorative effects of yokukansan, a traditional Japanese medicine, on learning and non-cognitive disturbances in the Tg2576 mouse model of Alzheimer's disease

(2008) Masahiro Tabuchi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Xanthones fromGentianella amarellassp.acutawith Acetylcholinesterase and Monoamine Oxidase Inhibitory Activities

(2008) A. Urbain et al.   JOURNAL OF NATURAL PRODUCTS

Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis

(2008) Mohammad A. Kamal et al.   JOURNAL OF NEURAL TRANSMISSION

BT-11 improves stress-induced memory impairments through increment of glucose utilization and total neural cell adhesion molecule levels in rat brains

(2008) Ki Young Shin et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Pharmacological profile of an essential oil derived fromMelissa officinaliswith anti-agitation properties: focus on ligand-gated channels

(2008) Sawsan Abuhamdah et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Cannabidiol for the treatment of psychosis in Parkinson’s disease

(2008) AW Zuardi et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Ginkgolides protect against amyloid-β1–42-mediated synapse damage in vitro

(2008) Clive Bate et al.   Molecular Neurodegeneration

Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK

(2008) Eun Sun Cho et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Attenuation of oxidative neuronal cell death by coffee phenolic phytochemicals

(2008) Eun Sun Cho et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Natural products to drugs: natural product-derived compounds in clinical trials

(2008) Mark S. Butler   NATURAL PRODUCT REPORTS

A pyrazole derivative of curcumin enhances memory

(2008) Pamela Maher et al.   NEUROBIOLOGY OF AGING

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

(2008) Saravanan S. Karuppagounder et al.   NEUROCHEMISTRY INTERNATIONAL

Nordihydroguaiaretic acid activates the antioxidant pathway Nrf2/HO-1 and protects cerebellar granule neurons against oxidative stress

(2008) Silvia Guzmán-Beltrán et al.   NEUROSCIENCE LETTERS

Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus

(2008) Barbara Shukitt-Hale et al.   NUTRITIONAL NEUROSCIENCE

Effect of Yi-Gan San on psychiatric symptoms and sleep structure at patients with behavioral and psychological symptoms of dementia

(2008) Hideto Shinno et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Effect of yokukansan on the behavioral and psychological symptoms of dementia in elderly patients with Alzheimer's disease

(2008) Akira Monji et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Galantamine-induced improvements in cognitive function are not related to alterations in α4β2 nicotinic receptors in early Alzheimer’s disease as measured in vivo by 2-[18F]Fluoro-A-85380 PET

(2008) J. R. Ellis et al.   PSYCHOPHARMACOLOGY