The Impact of Pancreatic Beta Cell Heterogeneity on Type 1 Diabetes Pathogenesis
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Impact of Pancreatic Beta Cell Heterogeneity on Type 1 Diabetes Pathogenesis
Authors
Keywords
-
Journal
Current Diabetes Reports
Volume 18, Issue 11, Pages -
Publisher
Springer Nature America, Inc
Online
2018-09-24
DOI
10.1007/s11892-018-1085-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Deciphering Pancreatic Islet β Cell and α Cell Maturation Pathways and Characteristic Features at the Single-Cell Level
- (2018) Wei-Lin Qiu et al. Cell Metabolism
- Pseudotime Ordering of Single Human β-Cells Reveals States of Insulin Production and Unfolded Protein Response
- (2018) Yurong Xin et al. DIABETES
- Verapamil and beta cell function in adults with recent-onset type 1 diabetes
- (2018) Fernando Ovalle et al. NATURE MEDICINE
- Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men
- (2018) Patrik Rorsman et al. PHYSIOLOGICAL REVIEWS
- Replication confers β cell immaturity
- (2018) Sapna Puri et al. Nature Communications
- Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes
- (2018) Kevin C. Osum et al. Scientific Reports
- β Cells Persist in T1D Pancreata Without Evidence of Ongoing β-Cell Turnover or Neogenesis
- (2017) Carol J Lam et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- δ-cells and β-cells are electrically coupled and regulate α-cell activity via somatostatin
- (2017) L. J. B. Briant et al. JOURNAL OF PHYSIOLOGY-LONDON
- Super-multiplex vibrational imaging
- (2017) Lu Wei et al. NATURE
- Sirolimus induces depletion of intracellular calcium stores and mitochondrial dysfunction in pancreatic beta cells
- (2017) Angela Lombardi et al. Scientific Reports
- Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose
- (2016) Natalie R. Johnston et al. Cell Metabolism
- Single-Cell Mass Cytometry Analysis of the Human Endocrine Pancreas
- (2016) Yue J. Wang et al. Cell Metabolism
- RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes
- (2016) Yurong Xin et al. Cell Metabolism
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
- (2016) Åsa Segerstolpe et al. Cell Metabolism
- Immune Intervention and Preservation of Pancreatic Beta Cell Function in Type 1 Diabetes
- (2016) Kimber M. Simmons et al. Current Diabetes Reports
- Islet Autoantibodies
- (2016) Vito Lampasona et al. Current Diabetes Reports
- Disallowance ofAcot7in β-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion
- (2016) Aida Martinez-Sanchez et al. DIABETES
- Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes
- (2016) Pia Leete et al. DIABETES
- Single-Cell Transcriptomics of the Human Endocrine Pancreas
- (2016) Yue J. Wang et al. DIABETES
- Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes
- (2016) Nathan Lawlor et al. GENOME RESEARCH
- Replicative capacity of β-cells and type 1 diabetes
- (2016) Diane Saunders et al. JOURNAL OF AUTOIMMUNITY
- Life and death of β cells in Type 1 diabetes: A comprehensive review
- (2016) Nicholas S. Wilcox et al. JOURNAL OF AUTOIMMUNITY
- Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes
- (2016) Francesca Cinti et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation
- (2016) Kira Meyerovich et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Identification of proliferative and mature β-cells in the islets of Langerhans
- (2016) Erik Bader et al. NATURE
- Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
- (2016) T. Delong et al. SCIENCE
- Immune and Pancreatic β Cell Interactions in Type 1 Diabetes
- (2016) Joanne Boldison et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice
- (2016) Ja Young Kim-Muller et al. Nature Communications
- Human islets contain four distinct subtypes of β cells
- (2016) Craig Dorrell et al. Nature Communications
- A Single-Cell Transcriptome Atlas of the Human Pancreas
- (2016) Mauro J. Muraro et al. Cell Systems
- A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure
- (2016) Maayan Baron et al. Cell Systems
- Glucokinase activation is beneficial or toxic to cultured rat pancreatic islets depending on the prevailing glucose concentration
- (2015) Leticia P. Roma et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Pancreatic β-cell identity, glucose sensing and the control of insulin secretion
- (2015) Guy A. Rutter et al. BIOCHEMICAL JOURNAL
- Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro
- (2015) Lars Krogvold et al. DIABETES
- Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes
- (2015) Martha Campbell-Thompson et al. DIABETES
- Single‐cell transcriptomes reveal characteristic features of human pancreatic islet cell types
- (2015) Jin Li et al. EMBO REPORTS
- Non-HLA gene effects on the disease process of type 1 diabetes: From HLA susceptibility to overt disease
- (2015) Johanna Lempainen et al. JOURNAL OF AUTOIMMUNITY
- Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells
- (2015) Mourad Ferdaoussi et al. JOURNAL OF CLINICAL INVESTIGATION
- Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion
- (2015) Talitha van der Meulen et al. NATURE MEDICINE
- Pancreatic and Duodenal Homeobox Protein 1 (Pdx-1) Maintains Endoplasmic Reticulum Calcium Levels through Transcriptional Regulation of Sarco-endoplasmic Reticulum Calcium ATPase 2b (SERCA2b) in the Islet β Cell
- (2014) Justin S. Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells
- (2014) Weida Li et al. NATURE BIOTECHNOLOGY
- Multiplexed ion beam imaging of human breast tumors
- (2014) Michael Angelo et al. NATURE MEDICINE
- Type 2 Diabetes and Congenital Hyperinsulinism Cause DNA Double-Strand Breaks and p53 Activity in β Cells
- (2013) Sharona Tornovsky-Babeay et al. Cell Metabolism
- Diabetes in the young – a global view and worldwide estimates of numbers of children with type 1 diabetes
- (2013) Chris Patterson et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Chromogranin A is a T cell antigen in human type 1 diabetes
- (2013) Peter A. Gottlieb et al. JOURNAL OF AUTOIMMUNITY
- Lipotoxicity disrupts incretin-regulated human β cell connectivity
- (2013) David J. Hodson et al. JOURNAL OF CLINICAL INVESTIGATION
- viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia
- (2013) El-ad David Amir et al. NATURE BIOTECHNOLOGY
- CLARITY for mapping the nervous system
- (2013) Kwanghun Chung et al. NATURE METHODS
- Insights into type 1 diabetes provided by genetic analyses
- (2013) Grant Morahan Current Opinion in Endocrinology Diabetes and Obesity
- Islet -Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model
- (2012) S. A. Tersey et al. DIABETES
- Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
- (2012) Ken T. Coppieters et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
- (2012) NATURE GENETICS
- Urocortin 3 Marks Mature Human Primary and Embryonic Stem Cell-Derived Pancreatic Alpha and Beta Cells
- (2012) Talitha van der Meulen et al. PLoS One
- Progressive Erosion of -Cell Function Precedes the Onset of Hyperglycemia in the NOD Mouse Model of Type 1 Diabetes
- (2011) D. Ize-Ludlow et al. DIABETES
- Residual Insulin Production and Pancreatic -Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study
- (2010) H. A. Keenan et al. DIABETES
- Evaluation of impaired β-cell function in nonobese-diabetic (NOD) mouse model using bioluminescence imaging
- (2010) Dror Sever et al. FASEB JOURNAL
- Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft
- (2009) E. H. Liu et al. DIABETOLOGIA
- Impact of Type 1 Diabetes and Insulin Treatment on Plasma Levels and Fractional Synthesis Rate of Retinol-Binding Protein 4
- (2009) Marion Jourdan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
- (2009) Chris Wallace et al. NATURE GENETICS
- Genetics of Type 1A Diabetes
- (2009) Patrick Concannon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Gap Junction Coupling and Calcium Waves in the Pancreatic Islet
- (2008) Richard K.P. Benninger et al. BIOPHYSICAL JOURNAL
- Pancreatic β-cell mass in European subjects with type 2 diabetes
- (2008) J. Rahier et al. DIABETES OBESITY & METABOLISM
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started