Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes

Inflammatory cytokines IL-17 and TNF-α up-regulate PD-L1 expression in human prostate and colon cancer cells

(2017) Xun Wang et al.   IMMUNOLOGY LETTERS

Cancer immunotherapy — immune checkpoint blockade and associated endocrinopathies

(2017) David J. Byun et al.   Nature Reviews Endocrinology

PD-1/PD-L and autoimmunity: A growing relationship

(2016) Mohammad Reza Zamani et al.   CELLULAR IMMUNOLOGY

National Institutes of Health–Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

(2016) Camillo Ricordi et al.   DIABETES

Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity

(2016) Tony T. Jiang et al.   Cell Reports

TGFβ-dependent expression of PD-1 and PD-L1 controls CD8+ T cell anergy in transplant tolerance

(2016) Marije Baas et al.   eLife

Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes

(2015) Martha Campbell-Thompson et al.   DIABETES

Immune Checkpoint Blockade in Cancer Therapy

(2015) Michael A. Postow et al.   JOURNAL OF CLINICAL ONCOLOGY

Cutting Edge: Identification of Autoreactive CD4+and CD8+T Cell Subsets Resistant to PD-1 Pathway Blockade

(2015) Kristen E. Pauken et al.   JOURNAL OF IMMUNOLOGY

PD-1/PD-L1 Costimulatory Pathway-induced Mouse Islet Transplantation Immune Tolerance

(2015) T. Li et al.   TRANSPLANTATION PROCEEDINGS

PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing

(2015) Ilseyar Akhmetzyanova et al.   PLoS Pathogens

PD-L1 gene polymorphisms and low serum level of PD-L1 protein are associated to type 1 diabetes in Chile

(2014) Carolina Pizarro et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

PD-1, but Not PD-L1, Expressed by Islet-Reactive CD4 + T Cells Suppresses Infiltration of the Pancreas During Type 1 Diabetes

(2013) Kristen E. Pauken et al.   DIABETES

Cutting Edge: Type 1 Diabetes Occurs despite Robust Anergy among Endogenous Insulin-Specific CD4 T Cells in NOD Mice

(2013) K. E. Pauken et al.   JOURNAL OF IMMUNOLOGY

The role of the PD-1 pathway in autoimmunity and peripheral tolerance

(2011) Brian T. Fife et al.   Annals of the New York Academy of Sciences

The Programmed Death-1 Ligand 1:B7-1 Pathway Restrains Diabetogenic Effector T Cells In Vivo

(2011) A. M. Paterson et al.   JOURNAL OF IMMUNOLOGY

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice

(2010) Scott N. Mueller et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice

(2009) Christophe M. Filippi et al.   JOURNAL OF CLINICAL INVESTIGATION

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

(2009) Brian T Fife et al.   NATURE IMMUNOLOGY

Protective Role of Programmed Death 1 Ligand 1 (PD-L1)in Nonobese Diabetic Mice: The Paradox in Transgenic Models

(2008) C.-J. Wang et al.   DIABETES

Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways

(2008) Brian T. Fife et al.   IMMUNOLOGICAL REVIEWS