Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice

Postoperative cognitive dysfunction: Involvement of neuroinflammation and neuronal functioning

(2014) Iris B. Hovens et al.   BRAIN BEHAVIOR AND IMMUNITY

Beneficial effects of deferoxamine against astrocyte death induced by modified oxygen glucose deprivation

(2014) Rui Zhang et al.   BRAIN RESEARCH

Intranasally-administered deferoxamine mitigates toxicity of 6-OHDA in a rat model of Parkinson׳s disease

(2014) J.M. Fine et al.   BRAIN RESEARCH

Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases

(2014) Hugo González et al.   JOURNAL OF NEUROIMMUNOLOGY

Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice

(2014) Ingrid R Niesman et al.   Journal of Neuroinflammation

The role of Nox2-derived ROS in the development of cognitive impairment after sepsis

(2014) Marina S Hernandes et al.   Journal of Neuroinflammation

The common inflammatory etiology of depression and cognitive impairment: a therapeutic target

(2014) David J Allison et al.   Journal of Neuroinflammation

Lipopolysaccharides Upregulate Hepcidin in Neuron via Microglia and the IL-6/STAT3 Signaling Pathway

(2014) Zhong-Ming Qian et al.   MOLECULAR NEUROBIOLOGY

The Potential for Transition Metal-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

(2014) David B. Lovejoy et al.   Frontiers in Aging Neuroscience

Mitochondrial iron-sulfur cluster dysfunction in neurodegenerative disease

(2014) Grazia Isaya   Frontiers in Pharmacology

The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: Insights into the potential of various iron therapies to induce oxidative and nitrosative stress

(2013) Taija S. Koskenkorva-Frank et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting dysregulation of brain iron homeostasis in Parkinson's disease by iron chelators

(2013) Orly Weinreb et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells

(2013) Pamela Urrutia et al.   JOURNAL OF NEUROCHEMISTRY

Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice

(2013) Marcus A Lawson et al.   Journal of Neuroinflammation

Toll-like receptor signaling adapter proteins govern spread of neuropathic pain and recovery following nerve injury in male mice

(2013) Jennifer A Stokes et al.   Journal of Neuroinflammation

GSK-3β overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo

(2013) M Llorens-Martín et al.   MOLECULAR PSYCHIATRY

Metal Dyshomeostasis and Inflammation in Alzheimer’s and Parkinson’s Diseases: Possible Impact of Environmental Exposures

(2013) Oddvar Myhre et al.   Oxidative Medicine and Cellular Longevity

Neuropeptides in sepsis: From brain pathology to systemic inflammation

(2013) Fabiano Pinheiro da Silva et al.   PEPTIDES

A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

(2013) Donal T. Skelly et al.   PLoS One

Regional siderosis: a new challenge for iron chelation therapy

(2013) Zvi Ioav Cabantchik et al.   Frontiers in Pharmacology

The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer’s disease

(2013) Animesh Raha et al.   Acta Neuropathologica Communications

Surgical Trauma Induces Iron Accumulation and Oxidative Stress in a Rodent Model of Postoperative Cognitive Dysfunction

(2012) Li-Na An et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

A single intraperitoneal injection of endotoxin in rats induces long-lasting modifications in behavior and brain protein levels of TNF-α and IL-18

(2012) Paola Bossù et al.   Journal of Neuroinflammation

TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation

(2012) Karim Belarbi et al.   Journal of Neuroinflammation

Recombinant human erythropoietin attenuates neuronal apoptosis and cognitive defects via JAK2/STAT3 signaling in experimental endotoxemia

(2012) Ting-Fa Zhou et al.   JOURNAL OF SURGICAL RESEARCH

Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease

(2012) Chuang Guo et al.   NEUROBIOLOGY OF AGING

Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain

(2012) Chuang Guo et al.   NEUROCHEMISTRY INTERNATIONAL

Hippocampal long-term depression mediates spatial reversal learning in the Morris water maze

(2012) Zhifang Dong et al.   NEUROPHARMACOLOGY

Lipopolysaccharide induces paired immunoglobulin-like receptor B (PirB) expression, synaptic alteration, and learning–memory deficit in rats

(2012) X.-H. Deng et al.   NEUROSCIENCE

Age-dependent neuroinflammatory responses and deficits in long-term potentiation in the hippocampus during systemic inflammation

(2012) X. Liu et al.   NEUROSCIENCE

Exendin-4 Protected against Cognitive Dysfunction in Hyperglycemic Mice Receiving an Intrahippocampal Lipopolysaccharide Injection

(2012) Hei-Jen Huang et al.   PLoS One

Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: effect of exogenous progesterone

(2011) Fang Hua et al.   Journal of Neuroinflammation

Central administration of insulin-like growth factor-I decreases depressive-like behavior and brain cytokine expression in mice

(2011) Sook-Eun Park et al.   Journal of Neuroinflammation

Ghrelin prevents neuronal apoptosis and cognitive impairments in sepsis-associated encephalopathy

(2011) Guobin Wang et al.   NEUROREPORT

Increased cellular iron levels affect matrix metalloproteinase expression and phagocytosis in activated microglia

(2011) Nootchanat Mairuae et al.   NEUROSCIENCE LETTERS

Spatial memory deficits and oxidative stress damage following exposure to lipopolysaccharide in a rodent model of Parkinson's disease

(2011) Lucian Hritcu et al.   NEUROSCIENCE RESEARCH

Regulation of apoptosis-associated lysosomal membrane permeabilization

(2010) Ann-Charlotte Johansson et al.   APOPTOSIS

Iron Leads to Memory Impairment that is Associated with a Decrease in Acetylcholinesterase Pathways

(2010) Vinicius Perez et al.   CURRENT NEUROVASCULAR RESEARCH

The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice

(2010) Wei-Jian Zhang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Central Administration of Lipopolysaccharide Induces Depressive-like Behavior in Vivo and Activates Brain Indoleamine 2,3 Dioxygenase In Murine Organotypic Hippocampal Slice Cultures

(2010) Xin Fu et al.   Journal of Neuroinflammation

Metals, oxidative stress and neurodegenerative disorders

(2010) Klaudia Jomova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Apoptosis Inhibition Can Be Threatening in Aβ-Induced Neuroinflammation, Through Promoting Cell Proliferation

(2010) A. Abdi et al.   NEUROCHEMICAL RESEARCH

Oxidative stress in Alzheimer disease: A possibility for prevention

(2010) David J. Bonda et al.   NEUROPHARMACOLOGY

Neuroinflammation and Cognitive Aging

(2010) Raymond L. Ownby   Current Psychiatry Reports

A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease

(2009) Pier Giorgio Mastroberardino et al.   NEUROBIOLOGY OF DISEASE

Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation

(2009) Carin Thomas et al.   REDOX REPORT

Iron-Induced Oxidative Injury Differentially Regulates PI3K/Akt/GSK3β Pathway in Synaptic Endings from Adult and Aged Rats

(2009) Romina María Uranga et al.   TOXICOLOGICAL SCIENCES

Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases

(2008) Catherine M. Cahill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cell functions impaired by frataxin deficiency are restored by drug-mediated iron relocation

(2008) O. Kakhlon et al.   BLOOD

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

(2008) Xian-Ping Dong et al.   NATURE

Neurodegeneration and Inflammation

(2008) Mark H. DeLegge et al.   NUTRITION IN CLINICAL PRACTICE

Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

(2008) J. Salazar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide

(2007) Y. Huang et al.   NEUROBIOLOGY OF AGING