Toll-like receptor signaling adapter proteins govern spread of neuropathic pain and recovery following nerve injury in male mice

Spinal Toll-like receptor signaling and nociceptive processing: Regulatory balance between TIRAP and TRIF cascades mediated by TNF and IFNβ

(2013) Jennifer A. Stokes et al.   PAIN

Toll/Interleukin-1 Receptor Domain-Containing Adapter Inducing Interferon-  Mediates Microglial Phagocytosis of Degenerating Axons

(2012) S. Hosmane et al.   JOURNAL OF NEUROSCIENCE

Minocycline attenuates mechanical allodynia and expression of spinal NMDA receptor 1 subunit in rat neuropathic pain model

(2012) Shaofeng Pu et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

(2012) Takashi Shichita et al.   NATURE MEDICINE

Bilateral Sensory Abnormalities in Patients with Unilateral Neuropathic Pain; A Quantitative Sensory Testing (QST) Study

(2012) Karl-Heinz Konopka et al.   PLoS One

Emerging role of Toll-like receptors in the control of pain and itch

(2012) Tong Liu et al.   Neuroscience Bulletin

Detailed characterization of neuro-immune responses following neuropathic injury in mice

(2011) Cristina Fabiola Kim et al.   BRAIN RESEARCH

A brief comparison of the pathophysiology of inflammatory versus neuropathic pain

(2011) Qinghao Xu et al.   Current Opinion in Anesthesiology

Two-week cast immobilization induced chronic widespread hyperalgesia in rats

(2011) Y. Ohmichi et al.   EUROPEAN JOURNAL OF PAIN

The mechanisms of microgliosis and pain following peripheral nerve injury

(2011) Margarita Calvo et al.   EXPERIMENTAL NEUROLOGY

Toll-like receptors in chronic pain

(2011) Lauren Nicotra et al.   EXPERIMENTAL NEUROLOGY

Functional Recovery after Peripheral Nerve Injury is Dependent on the Pro-Inflammatory Cytokines IL-1  and TNF: Implications for Neuropathic Pain

(2011) S. Nadeau et al.   JOURNAL OF NEUROSCIENCE

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

(2011) R. E. Sorge et al.   JOURNAL OF NEUROSCIENCE

Spinal glycinergic and GABAergic neurons expressing C-FOS after capsaicin stimulation are increased in rats with contralateral neuropathic pain

(2011) M. Hossaini et al.   NEUROSCIENCE

Transient tactile allodynia following intrathecal puncture in mouse: Contributions of Toll-like receptor signaling

(2011) Jennifer A. Stokes et al.   NEUROSCIENCE LETTERS

Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis

(2011) Christina A. Christianson et al.   PAIN

Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood–Brain Barrier From Ischemia-Induced Disruption in Rats

(2011) Jiyong Zhang et al.   STROKE

Bilateral mechanical and thermal hyperalgesia and tactile allodynia after chronic compression of dorsal root ganglion in mice

(2011) Rong-Gui Chen et al.   Neuroscience Bulletin

Spinal glial TLR4-mediated nociception and production of prostaglandin E2 and TNF

(2010) O Saito et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal models of neuropathic pain

(2010) Amteshwar Singh Jaggi et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Interferon (IFN) beta treatment induces major histocompatibility complex (MHC) class I expression in the spinal cord and enhances axonal growth and motor function recovery following sciatic nerve crush in mice

(2010) R. G. Zanon et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Bilateral widespread mechanical pain sensitivity in carpal tunnel syndrome: evidence of central processing in unilateral neuropathy

(2009) C. Fernandez-de-las-Penas et al.   BRAIN

Engulfment of Axon Debris by Microglia Requires p38 MAPK Activity

(2009) Tatsuhide Tanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

(2009) Hideyuki Yanai et al.   NATURE

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Unmasking the tonic-aversive state in neuropathic pain

(2009) Tamara King et al.   NATURE NEUROSCIENCE

Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats

(2009) M.R. Hutchinson et al.   NEUROSCIENCE

Bilateral thermal hyperalgesia in trigeminal and extra-trigeminal regions in patients with myofascial temporomandibular disorders

(2009) César Fernández-de-las-Peñas et al.   EXPERIMENTAL BRAIN RESEARCH

Bilateral hand/wrist heat and cold hyperalgesia, but not hypoesthesia, in unilateral carpal tunnel syndrome

(2009) Ana Isabel de la Llave-Rincón et al.   EXPERIMENTAL BRAIN RESEARCH

Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4)

(2008) Mark R. Hutchinson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Glial TLR4 receptor as new target to treat neuropathic pain: Efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice

(2008) Isabella Bettoni et al.   GLIA

TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events

(2008) Karen A. Cavassani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of Interleukin (IL)-18 in experimental paracoccidioidomycosis

(2008) Luciano A. Panagio et al.   MEDICAL MYCOLOGY

The contributing role of CD14 in toll-like receptor 4 dependent neuropathic pain

(2008) L. Cao et al.   NEUROSCIENCE

Toll-like receptor signaling in endogenous neuroprotection and stroke

(2008) B.J. Marsh et al.   NEUROSCIENCE

Spinal glial activation contributes to pathological pain states

(2008) Hong Cao et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Interaction of Hyperalgesia and Sensory Loss in Complex Regional Pain Syndrome Type I (CRPS I)

(2008) Volker Huge et al.   PLoS One

Nociceptive behavior in animal models for peripheral neuropathy: Spinal and supraspinal mechanisms

(2008) Nayef E. Saadé et al.   PROGRESS IN NEUROBIOLOGY