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Title
Updating the Wnt pathways
Authors
Keywords
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Journal
BIOSCIENCE REPORTS
Volume 34, Issue 5, Pages 593-607
Publisher
Portland Press Ltd.
Online
2014-09-15
DOI
10.1042/bsr20140119
References
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Note: Only part of the references are listed.- YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
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- (2014) Meritxell Vinyoles et al. MOLECULAR CELL
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- (2014) Sergio P. Acebron et al. MOLECULAR CELL
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- (2014) Kai Wang et al. NATURE GENETICS
- Can we safely target the WNT pathway?
- (2014) Michael Kahn NATURE REVIEWS DRUG DISCOVERY
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- (2013) V. Luga et al. CANCER RESEARCH
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- (2013) Charles P. Xavier et al. CELLULAR SIGNALLING
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- (2013) Yang Xie et al. EMBO REPORTS
- The structural basis of R-spondin recognition by LGR5 and RNF43
- (2013) P.-H. Chen et al. GENES & DEVELOPMENT
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- (2013) D. Wang et al. GENES & DEVELOPMENT
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- (2013) C. Deng et al. JOURNAL OF CELL SCIENCE
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- (2013) H. Yamamoto et al. JOURNAL OF CELL SCIENCE
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- (2012) Vivian S.W. Li et al. CELL
- Wnt/β-Catenin Signaling and Disease
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- (2012) Rani Najdi et al. DIFFERENTIATION
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