Mammalian Iron Homeostasis in Health and Disease: Uptake, Storage, Transport, and Molecular Mechanisms of Action

Duodenal Cytochrome B Expression Stimulates Iron Uptake by Human Intestinal Epithelial Cells

(2018) Gladys O. Latunde-Dada et al.   JOURNAL OF NUTRITION

Mitochondrial Iron Metabolism and Its Role in Neurodegeneration

(2017) Maxx P. Horowitz et al.   JOURNAL OF ALZHEIMERS DISEASE

Folate and Vitamin B12 Metabolism: Overview and Interaction with Riboflavin, Vitamin B6, and Polymorphisms

(2015) Barry Shane   FOOD AND NUTRITION BULLETIN

A High Prevalence of Biochemical Evidence of Vitamin B12 or Folate Deficiency does not Translate into a Comparable Prevalence of Anemia

(2015) Jack Metz   FOOD AND NUTRITION BULLETIN

Review article: the iron overload syndromes

(2012) A. Siddique et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Microbial siderophores: a mini review

(2012) Ratul Saha et al.   JOURNAL OF BASIC MICROBIOLOGY

Improved differential diagnosis of anemia of chronic disease and iron deficiency anemia: A prospective multicenter evaluation of soluble transferrin receptor and the sTfR/log ferritin index

(2011) Barry S. Skikne et al.   AMERICAN JOURNAL OF HEMATOLOGY

Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron

(2011) Jorge J. Pinilla-Tenas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Anemia—still a major health problem in many parts of the world!

(2011) Nils Milman   ANNALS OF HEMATOLOGY

The HIF Pathway and Erythrocytosis

(2011) Frank S. Lee et al.   Annual Review of Pathology-Mechanisms of Disease

Mitochondrial Mayhem: The Mitochondrion as a Modulator of Iron Metabolism and Its Role in Disease

(2011) Michael Li-Hsuan Huang et al.   ANTIOXIDANTS & REDOX SIGNALING

Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites

(2011) Melissa B. Pappalardi et al.   BIOCHEMICAL JOURNAL

Hypoxic preconditioning increases iron transport rate in astrocytes

(2011) Lei Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis

(2011) W. Chen et al.   BLOOD

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats

(2011) I. Theurl et al.   BLOOD

Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice

(2011) A. U. Steinbicker et al.   BLOOD

Vitamin C is dispensable for oxygen sensing in vivo

(2011) K. J. Nytko et al.   BLOOD

Hepcidin and iron regulation, 10 years later

(2011) T. Ganz   BLOOD

Expression of the H-subunit and L-subunit of ferritin in bone marrow macrophages and cells of the erythron during cellular immune activation

(2011) A.M. Koorts et al.   BLOOD CELLS MOLECULES AND DISEASES

Optimal management of β thalassaemia intermedia

(2011) Ali T. Taher et al.   BRITISH JOURNAL OF HAEMATOLOGY

Recent insights into iron import by bacteria

(2011) Volkmar Braun et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

New roles for bacterial siderophores in metal transport and tolerance

(2011) Isabelle J. Schalk et al.   ENVIRONMENTAL MICROBIOLOGY

Duodenal cytochrome b (Cybrd 1) and HIF-2α expression during acute hypoxic exposure in mice

(2011) Gladys O. Latunde-Dada et al.   EUROPEAN JOURNAL OF NUTRITION

Intestinal DMT1 Cotransporter Is Down-regulated by Hepcidin via Proteasome Internalization and Degradation

(2011) Carole Brasse–Lagnel et al.   GASTROENTEROLOGY

Conditional disruption of mouse HFE2 gene: Maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin

(2011) Konstantinos Gkouvatsos et al.   HEPATOLOGY

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

(2011) Emilio Ramos et al.   HEPATOLOGY

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice

(2011) Elena Corradini et al.   HEPATOLOGY

The role of lysosomes in iron metabolism and recycling

(2011) Tino Kurz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Essential Role of Endocytosis of the Type II Transmembrane Serine Protease TMPRSS6 in Regulating Its Functionality

(2011) François Béliveau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of divalent metal transporter 1 in primary hippocampal neurons: reconsidering its role in non-transferrin-bound iron influx

(2011) Ilaria Pelizzoni et al.   JOURNAL OF NEUROCHEMISTRY

Iron Homeostasis and Nutritional Iron Deficiency

(2011) Elizabeth C. Theil   JOURNAL OF NUTRITION

Cytochromes—fascinating molecular machines

(2011) Peter H. Roos et al.   Metallomics

Molecular mechanism of intestinal iron absorption

(2011) Okhee Han   Metallomics

Metal use in ribonucleotide reductase R2, di-iron, di-manganese and heterodinuclear—an intricate bioinorganic workaround to use different metals for the same reaction

(2011) Martin Högbom   Metallomics

An alternative view of the proposed alternative activities of hemopexin

(2011) Marcia R. Mauk et al.   PROTEIN SCIENCE

Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders

(2011) Clara Camaschella et al.   TheScientificWorldJOURNAL

Aberrant Expression of TfR1/CD71 in Thyroid Carcinomas Identifies a Novel Potential Diagnostic Marker and Therapeutic Target

(2011) Gaetano Magro et al.   THYROID

Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype

(2011) Gaetano Cairo et al.   TRENDS IN IMMUNOLOGY

Iron-Sensing Proteins that Regulate Hepcidin and Enteric Iron Absorption

(2010) Mitchell D. Knutson   Annual Review of Nutrition

Iron Regulatory Proteins: From Molecular Mechanisms to Drug Development

(2010) Stefania Recalcati et al.   ANTIOXIDANTS & REDOX SIGNALING

Trans-Plasma Membrane Electron Transport in Mammals: Functional Significance in Health and Disease

(2010) Domenico Del Principe et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular enzymology of lipoxygenases

(2010) Igor Ivanov et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents

(2010) Emily Flashman et al.   BIOCHEMICAL JOURNAL

Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron

(2010) Darius J.R. Lane et al.   BIOCHEMICAL JOURNAL

Human Iron−Sulfur Cluster Assembly, Cellular Iron Homeostasis, and Disease

(2010) Hong Ye et al.   BIOCHEMISTRY

The Ferritin-like superfamily: Evolution of the biological iron storeman from a rubrerythrin-like ancestor

(2010) Simon C. Andrews   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hepcidin expression by human monocytes in response to adhesion and pro-inflammatory cytokines

(2010) Xiaolan Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The iron redox and hydrolysis chemistry of the ferritins

(2010) Fadi Bou-Abdallah   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Structure and reactivity of hexacoordinate hemoglobins

(2010) Smita Kakar et al.   BIOPHYSICAL CHEMISTRY

Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis

(2010) H. Forejtnikova et al.   BLOOD

Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis

(2010) K. E. Finberg et al.   BLOOD

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6

(2010) A. Lenoir et al.   BLOOD

Bone loss caused by iron overload in a murine model: importance of oxidative stress

(2010) J. Tsay et al.   BLOOD

Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice

(2010) J. Gao et al.   BLOOD

Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis

(2010) D. H. Lee et al.   BLOOD

Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis

(2010) W. Chen et al.   BLOOD

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Intestinal Ferritin H Is Required for an Accurate Control of Iron Absorption

(2010) Liviu Vanoaica et al.   Cell Metabolism

Both Nramp1 and DMT1 are necessary for efficient macrophage iron recycling

(2010) Shan Soe-Lin et al.   EXPERIMENTAL HEMATOLOGY

Regulation of iron pathways in response to hypoxia

(2010) Nikolai L. Chepelev et al.   FREE RADICAL BIOLOGY AND MEDICINE

Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation

(2010) M. Poli et al.   HAEMATOLOGICA

Iron overload induces BMP6 expression in the liver but not in the duodenum

(2010) L. Kautz et al.   HAEMATOLOGICA

Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis

(2010) John D. Ryan et al.   HEPATOLOGY

Factors influencing disease phenotype and penetrance in HFE haemochromatosis

(2010) J. Rochette et al.   HUMAN GENETICS

Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors

(2010) Samira Lakhal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin

(2010) Ningning Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-mediated biological control

(2010) Jessica Cassavaugh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Divalent metal transporter 1 is a hypoxia-inducible gene

(2010) Zhong-Ming Qian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Disorders of iron metabolism. Part 1: molecular basis of iron homoeostasis

(2010) M. Munoz et al.   JOURNAL OF CLINICAL PATHOLOGY

Myoglobin's old and new clothes: from molecular structure to function in living cells

(2010) G. Gros et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Hepcidin in human iron disorders: Therapeutic implications

(2010) Antonello Pietrangelo   JOURNAL OF HEPATOLOGY

Synergistic accumulation of iron and zinc by cultured astrocytes

(2010) Glenda M. Bishop et al.   JOURNAL OF NEURAL TRANSMISSION

Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1

(2010) Jerome A. Roth et al.   JOURNAL OF NEUROCHEMISTRY

Increased striatal injury and behavioral deficits after intracerebral hemorrhage in hemopexin knockout mice

(2010) Lifen Chen et al.   JOURNAL OF NEUROSURGERY

Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation

(2010) David U. Mick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Accumulation of Non-Transferrin-Bound Iron by Neurons, Astrocytes, and Microglia

(2010) Glenda M. Bishop et al.   NEUROTOXICITY RESEARCH

Tryptophan Hydroxylase as Novel Target for the Treatment of Depressive Disorders

(2010) Susann Matthes et al.   PHARMACOLOGY

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

(2010) D. R. Richardson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the carbon monoxide complex of human cytoglobin

(2010) Masatomo Makino et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Central Role for Free Heme in the Pathogenesis of Severe Sepsis

(2010) R. Larsen et al.   Science Translational Medicine

Iron–sulfur proteins in health and disease

(2010) Alex Sheftel et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Battle for Iron between Bacterial Pathogens and Their Vertebrate Hosts

(2010) Eric P. Skaar   PLoS Pathogens

Hemoglobin and Heme Scavenger Receptors

(2009) Marianne Jensby Nielsen et al.   ANTIOXIDANTS & REDOX SIGNALING

Iron Homeostasis and Its Interaction with Prolyl Hydroxylases

(2009) David R. Mole   ANTIOXIDANTS & REDOX SIGNALING

Transplasma membrane electron transport comes in two flavors

(2009) Darius J. R. Lane et al.   BIOFACTORS

Hepcidin, the hormone of iron metabolism, is bound specifically to  -2-macroglobulin in blood

(2009) G. Peslova et al.   BLOOD

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression

(2009) L. Kautz et al.   BLOOD

Stoichiometries of transferrin receptors 1 and 2 in human liver

(2009) Maja Chloupková et al.   BLOOD CELLS MOLECULES AND DISEASES

A common SNP near BMP2 is associated with severity of the iron burden in HFE p.C282Y homozygous patients: A follow-up study

(2009) Jacqueline Milet et al.   BLOOD CELLS MOLECULES AND DISEASES

A novel association between a SNP inCYBRD1and serum ferritin levels in a cohort study ofHFEhereditary haemochromatosis

(2009) Clare C. Constantine et al.   BRITISH JOURNAL OF HAEMATOLOGY

Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency

(2009) Yatrik M. Shah et al.   Cell Metabolism

Regulation of Intestinal Iron Absorption: The Mucosa Takes Control?

(2009) Robert J. Simpson et al.   Cell Metabolism

Living with Iron (and Oxygen): Questions and Answers about Iron Homeostasis

(2009) Elizabeth C. Theil et al.   CHEMICAL REVIEWS

Ascorbate and plasma membrane electron transport—Enzymes vs efflux

(2009) Darius J.R. Lane et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis

(2009) Elena Corradini et al.   GASTROENTEROLOGY

Iron-Induced Expression of Bone Morphogenic Protein 6 in Intestinal Cells Is the Main Regulator of Hepatic Hepcidin Expression In Vivo

(2009) Stephanie Arndt et al.   GASTROENTEROLOGY

Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes

(2009) G. Ramey et al.   HAEMATOLOGICA

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

(2009) Daniel F. Wallace et al.   HEPATOLOGY

The global burden of iron overload

(2009) Marnie J. Wood et al.   Hepatology International

Hemojuvelin-Neogenin Interaction Is Required for Bone Morphogenic Protein-4-induced Hepcidin Expression

(2009) An-Sheng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding Modes of Aromatic Ligands to Mammalian Heme Peroxidases with Associated Functional Implications

(2009) Amit K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme–Hemopexin Complex Attenuates Neuronal Cell Death and Stroke Damage

(2009) Rung-chi Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

HIF-2α, but not HIF-1α, promotes iron absorption in mice

(2009) Maria Mastrogiannaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Hemopexin down-regulates LPS-induced proinflammatory cytokines from macrophages

(2009) Xueya Liang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Time to fatigue is increased in mouse muscle at 37°C; the role of iron and reactive oxygen species

(2009) Trent F. Reardon et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

(2009) Delphine Meynard et al.   NATURE GENETICS

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

(2009) Billy Andriopoulos Jr et al.   NATURE GENETICS

Pathways and mechanisms of endocytic recycling

(2009) Barth D. Grant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evidence for a Lack of a Direct Transcriptional Suppression of the Iron Regulatory Peptide Hepcidin by Hypoxia-Inducible Factors

(2009) Melanie Volke et al.   PLoS One

Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo

(2009) S. Soe-Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An E3 Ligase Possessing an Iron-Responsive Hemerythrin Domain Is a Regulator of Iron Homeostasis

(2009) A. A. Salahudeen et al.   SCIENCE

Homing in on iron homeostasis in plants

(2009) Jeeyon Jeong et al.   TRENDS IN PLANT SCIENCE

Hepcidin modulation in human diseases: From research to clinic

(2009) Alberto Piperno et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Hemopexin Prevents Endothelial Damage and Liver Congestion in a Mouse Model of Heme Overload

(2008) Francesca Vinchi et al.   AMERICAN JOURNAL OF PATHOLOGY

The power plant of the cell is also a smithy: The emerging role of mitochondria in cellular iron homeostasis

(2008) Alex D. Sheftel et al.   ANNALS OF MEDICINE

Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network

(2008) Martina U. Muckenthaler et al.   Annual Review of Nutrition

Siderophores in Fungal Physiology and Virulence

(2008) Hubertus Haas et al.   Annual Review of Phytopathology

Transferrin fails to provide protection against Fas-induced hepatic injury in mice with deletion of functional transferrin-receptor type 2

(2008) Vladimir Lesnikov et al.   APOPTOSIS

Iron metabolism in the anemia of chronic disease

(2008) Günter Weiss   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Ferritins: A family of molecules for iron storage, antioxidation and more

(2008) Paolo Arosio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The role of iron in type 2 diabetes in humans

(2008) Swapnil N. Rajpathak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents

(2008) D.R. Richardson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

(2008) A. R. Folgueras et al.   BLOOD

Forging a field: the golden age of iron biology

(2008) N. C. Andrews   BLOOD

Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2

(2008) N. J. Foot et al.   BLOOD

Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency

(2008) F. Guillem et al.   BLOOD

Iron responses in hepatic, intestinal and macrophage/monocyte cell lines under different culture conditions

(2008) Sandrine Jacolot et al.   BLOOD CELLS MOLECULES AND DISEASES

Hfe Acts in Hepatocytes to Prevent Hemochromatosis

(2008) Maja Vujić Spasić et al.   Cell Metabolism

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

(2008) Paul J. Schmidt et al.   Cell Metabolism

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

(2008) Laura Silvestri et al.   Cell Metabolism

The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function

(2008) Vladimir Marshansky et al.   CURRENT OPINION IN CELL BIOLOGY

Metals in Alzheimer's and Parkinson's Diseases

(2008) Kevin J Barnham et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The functional duality of iron regulatory protein 1

(2008) Karl Volz   CURRENT OPINION IN STRUCTURAL BIOLOGY

Ascorbic acid uptake affects ferritin, Dcytb and Nramp2 expression in Caco-2 cells

(2008) Nathalie M. Scheers et al.   EUROPEAN JOURNAL OF NUTRITION

Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms

(2008) An-Sheng Zhang et al.   EXPERIMENTAL HEMATOLOGY

A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron

(2008) M. A. Melis et al.   HAEMATOLOGICA

Insights on Regulation and Function of the Iron Regulatory Protein 1 (IRP1)

(2008) Jian Wang et al.   HEMOGLOBIN

Neogenin-mediated Hemojuvelin Shedding Occurs after Hemojuvelin Traffics to the Plasma Membrane

(2008) An-Sheng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-transferrin Iron Reduction and Uptake Are Regulated by Transmembrane Ascorbate Cycling in K562 Cells

(2008) Darius J. R. Lane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Iron Homeostasis: Recently Identified Proteins Provide Insight into Novel Control Mechanisms

(2008) An-Sheng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlation between the expression of divalent metal transporter 1 and the content of hypoxia-inducible factor-1 in hypoxic HepG2 cells

(2008) Zhu Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells

(2008) Maria Vittoria Verga Falzacappa et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Small-Molecule Inhibitors of HIF-2a Translation Link Its 5′UTR Iron-Responsive Element to Oxygen Sensing

(2008) Michael Zimmer et al.   MOLECULAR CELL

Slc39a14 Gene Encodes ZIP14, A Metal/Bicarbonate Symporter: Similarities to the ZIP8 Transporter

(2008) K. Girijashanker et al.   MOLECULAR PHARMACOLOGY

Expanding chemical biology of 2-oxoglutarate oxygenases

(2008) Christoph Loenarz et al.   Nature Chemical Biology

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

Genetics of iron regulation and the possible role of iron in Parkinson's disease

(2008) Shannon L. Rhodes et al.   NEUROBIOLOGY OF DISEASE

Iron Deficiency Anemia

(2008) Susan F. Clark   NUTRITION IN CLINICAL PRACTICE

A Cytosolic Iron Chaperone That Delivers Iron to Ferritin

(2008) H. Shi et al.   SCIENCE

The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

(2008) X. Du et al.   SCIENCE

Function of the hemochromatosis protein HFE: Lessons from animal models

(2008) Kostas Pantopoulos   WORLD JOURNAL OF GASTROENTEROLOGY

The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin

(2007) Isabella Zanella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

(2007) L. Silvestri et al.   BLOOD

Neuroglobin: an endogenous neuroprotectant

(2007) D GREENBERG et al.   CURRENT OPINION IN PHARMACOLOGY

Intracellular labile iron

(2007) William Breuer et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Macrophages function as a ferritin iron source for cultured human erythroid precursors

(2007) Moshe J. Leimberg et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Transferrin receptor 2 mediates uptake of transferrin-bound and non-transferrin-bound iron

(2007) Ross M. Graham et al.   JOURNAL OF HEPATOLOGY

Regulation of iron acquisition and storage: consequences for iron-linked disorders

(2007) Ivana De Domenico et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY