Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice

Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation

(2011) A. U. Steinbicker et al.   BLOOD

Anemia of Inflammation

(2011) C. N. Roy   Hematology-American Society of Hematology Education Program

Molecular Mechanisms of Hepcidin Regulation: Implications for the Anemia of CKD

(2010) Jodie L. Babitt et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis

(2010) D. H. Lee et al.   BLOOD

BMP6 Treatment Compensates for the Molecular Defect and Ameliorates Hemochromatosis in Hfe Knockout Mice

(2010) Elena Corradini et al.   GASTROENTEROLOGY

Iron overload induces BMP6 expression in the liver but not in the duodenum

(2010) L. Kautz et al.   HAEMATOLOGICA

Hepcidin in human iron disorders: Therapeutic implications

(2010) Antonello Pietrangelo   JOURNAL OF HEPATOLOGY

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression

(2009) L. Kautz et al.   BLOOD

Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis

(2009) Elena Corradini et al.   GASTROENTEROLOGY

Hepcidin targets ferroportin for degradation in hepatocytes

(2009) G. Ramey et al.   HAEMATOLOGICA

Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis

(2009) Shawn C. Little et al.   NATURE CELL BIOLOGY

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

(2009) Delphine Meynard et al.   NATURE GENETICS

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

(2009) Billy Andriopoulos Jr et al.   NATURE GENETICS

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

(2008) L. Kautz et al.   BLOOD