Recent developments in palladium-catalysed non-directed coupling of (hetero)arene C–H bonds with C–Z (Z = B, Si, Sn, S, N, C, H) bonds in bi(hetero)aryl synthesis

Theoretical Elucidation of Potential Enantioselectivity in a Pd-Catalyzed Aromatic C–H Coupling Reaction

(2017) Yoshio Nishimoto et al.   JOURNAL OF ORGANIC CHEMISTRY

Regiodivergent Cross-Dehydrogenative Coupling of Pyridines and Benzoxazoles: Discovery of Organic Halides as Regio-Switching Oxidants

(2016) Shuya Yamada et al.   ORGANIC LETTERS

Pd(II)-Catalyzed C3-Selective Arylation of Pyridine with (Hetero)arenes

(2016) Guo-Lin Gao et al.   ORGANIC LETTERS

Unraveling innate substrate control in site-selective palladium-catalyzed C–H heterocycle functionalization

(2016) Hwanho Choi et al.   Chemical Science

Bidentate, Monoanionic Auxiliary-Directed Functionalization of Carbon–Hydrogen Bonds

(2015) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations

(2015) Chao Liu et al.   CHEMICAL REVIEWS

Regioselective Direct C-3 Arylation of Imidazo[1,2-a]pyridines with Aryl Tosylates and Mesylates Promoted by Palladium–Phosphine Complexes

(2015) Pui Ying Choy et al.   JOURNAL OF ORGANIC CHEMISTRY

Oxygen as an oxidant in palladium/copper-cocatalyzed oxidative C-H/C-H cross-coupling between two heteroarenes

(2015) Yang Shi et al.   Science China-Chemistry

Functionalization of C–H Bonds via Metal-Catalyzed Desulfitative Coupling: An Alternative Tool for Access to Aryl- or Alkyl-Substituted (Hetero)arenes

(2015) Kedong Yuan et al.   ACS Catalysis

Palladium-Catalysed, Directed CH Coupling with Organometallics

(2014) Ramesh Giri et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-Catalyzed Direct CH Functionalization of Benzoquinone

(2014) Sarah E. Walker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly regioselective palladium-catalyzed direct cross-coupling of imidazo[1,2-a]pyridines with arylboronic acids

(2014) Limin Zhao et al.   CATALYSIS COMMUNICATIONS

Palladium-catalyzed oxidative CH/CH cross-coupling of pyridine N-oxides with five-membered heterocycles

(2014) Wei Liu et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Direct Arylation of Polyfluoroarenes with Organosilicon Reagents

(2014) Huixin Fan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Decarboxylative C-H Bond Arylation of Furans

(2014) Kai Pei et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Direct palladium-catalyzed desulfitative CC coupling of polyfluoroarenes with arylsulfinate salts: Water-accelerated reactions

(2014) Xiaoxi Lin et al.   JOURNAL OF FLUORINE CHEMISTRY

Palladium-catalyzed oxidative C–H/C–H cross-couplings of thiazolo[5,4-d]pyrimidine with aromatic (hetero)cycles

(2014) Sheng-Wei Yang et al.   TETRAHEDRON

Pd-catalyzed oxidative cross-coupling of imidazo[1,2-a]pyridine with arenes

(2014) Shaohua Wang et al.   TETRAHEDRON LETTERS

Pd(II)-catalyzed regioselective direct arylation of uracil via oxidative Heck reaction using arylboronic acids

(2014) Biplab Mondal et al.   TETRAHEDRON LETTERS

Palladium catalyzed oxidative Suzuki coupling reaction of indolizine at the 3-position using oxygen gas as the only oxidant

(2014) Huayou Hu et al.   RSC Advances

Pd-catalyzed oxidative C–H arylation of heterocycle embedded thiophene/furan with aryl boronic acid/ester

(2014) R. Srinivasan et al.   RSC Advances

C2-Arylation of Substituted PyridineN-oxides with Heteroaryl Carboxylic Acids by Palladium-Catalyzed Decarboxylative Coupling

(2014) Rajendran Suresh et al.   Asian Journal of Organic Chemistry

Palladium-Catalyzed Desulfitative Direct CH Arylation of Electron-Deficient Polyfluoroarenes with Sodium Arenesulfinates

(2013) Tao Miao et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-Catalyzed Direct Denitrogenative C-3-Arylation of 1H-Indoles with Arylhydrazines using Air as the Oxidant

(2013) Yongxin Chen et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct CH Bond Arylation of Indoles with Aryl Boronic Acids Catalyzed by Palladium Nanoparticles Encapsulated in Mesoporous Metal-Organic Framework

(2013) Yuanbiao Huang et al.   ChemCatChem

C4-Selective Oxidative Coupling of Thiophenes with Arylboron Compounds: Influence of Solvent Acidity and Boron Substitution

(2013) Ingo Schnapperelle et al.   ChemCatChem

Palladium-Catalyzed Cross-Dehydrogenative Functionalization of C(sp2)H Bonds

(2013) Yinuo Wu et al.   Chemistry-An Asian Journal

Microwave-Accelerated Pd-Catalyzed Desulfitative Direct C2-Arylation of Free (NH)-Indoles with Arylsulfinic Acids

(2013) Tao Miao et al.   Chemistry-An Asian Journal

Site-Selective Direct Arylation of 1,2,3-TriazoleN-Oxides

(2013) Wei Liu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Preparation of fluorinated biaryls through direct palladium-catalyzed coupling of polyfluoroarenes with aryltrifluoroborates

(2013) Xin Fang et al.   JOURNAL OF FLUORINE CHEMISTRY

Direct C-2 Arylation of 7-Azaindoles: Chemoselective Access to Multiarylated Derivatives

(2013) Prakash Kannaboina et al.   ORGANIC LETTERS

Pd-Catalyzed Oxidative CH/CH Direct Coupling of Heterocyclic N-Oxides

(2013) Wei Liu et al.   ORGANIC LETTERS

Palladium-Catalyzed C-2 Selective Arylation of Quinolines

(2013) Xiaoyu Ren et al.   ORGANIC LETTERS

Pd(OAc)2 catalyzed C–H activation of 1,3,4-oxadiazoles and their direct oxidative coupling with benzothiazoles and aryl boronic acids using Cu(OAc)2 as an oxidant

(2013) N. Salvanna et al.   TETRAHEDRON

Recent advances in the synthesis and properties of 4-, 5-, 6- or 7-azaindoles

(2013) Jean-Yves Mérour et al.   TETRAHEDRON

Pd-catalyzed decarboxylative cross-coupling of perfluorobenzoic acids with simple arenes

(2013) Hai-Qing Luo et al.   TETRAHEDRON LETTERS

Pd-catalyzed oxidative cross-coupling between two electron rich heteroarenes

(2013) Chun-Yang He et al.   Chemical Science

Aromatic C–H coupling with hindered arylboronic acids by Pd/Fe dual catalysts

(2013) Kazuya Yamaguchi et al.   Chemical Science

Programmed synthesis of arylthiazoles through sequential C–H couplings

(2013) Satoshi Tani et al.   Chemical Science

Controlling Site Selectivity in Palladium-Catalyzed C–H Bond Functionalization

(2012) Sharon R. Neufeldt et al.   ACCOUNTS OF CHEMICAL RESEARCH

Palladium-Catalyzed Direct and Site-Selective Desulfitative Arylation of Indoles with Sodium Sulfinates

(2012) Mingyue Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Pd(ii)-catalyzed direct C5-arylation of azole-4-carboxylates through double C–H bond cleavage

(2012) Ziyuan Li et al.   CHEMICAL COMMUNICATIONS

Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

(2012) Ge Wu et al.   CHEMICAL COMMUNICATIONS

Palladium(II)-Catalyzed Oxidative CH/CH Cross-Coupling between Two Structurally Similar Azoles

(2012) Jiaxing Dong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Direct Arylation of N-Heteroarenes with Arylsulfonyl Hydrazides

(2012) Bo Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Heck-Type Cross-Dehydrogenative Coupling Reactions of Indolizines at the 3-Position with Electron-Deficient Alkenes through Palladium-Catalyzed CH Activation

(2012) Huayou Hu et al.   Chemistry-An Asian Journal

Palladium-Catalyzed C–H Activation Taken to the Limit. Flattening an Aromatic Bowl by Total Arylation

(2012) Qianyan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed C-3 functionalization of indolizines via C–H bond cleavage

(2012) Baoli Zhao   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-catalyzed desulfitative arylation of azoles with arylsulfonyl hydrazides

(2012) Xinzhang Yu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Pd-Catalyzed β-Selective Direct C–H Bond Arylation of Thiophenes with Aryltrimethylsilanes

(2012) Kenji Funaki et al.   ORGANIC LETTERS

Palladium(II)-Catalyzed Coupling of Electron-Deficient Arenes via C–H Activation

(2012) Lihong Zhou et al.   ORGANOMETALLICS

Tuning the Regioselectivity of Palladium-Catalyzed Direct Arylation of Azoles by Metal Coordination

(2012) Serge I. Gorelsky   ORGANOMETALLICS

A highly efficient palladium-catalyzed desulfitative arylation of azoles with sodium arylsulfinates

(2012) Min Wang et al.   TETRAHEDRON

Dual C–H activations of electron-deficient heteroarenes: palladium-catalyzed oxidative cross coupling of thiazoles with azine N-oxides

(2012) Xiao-Pu Fu et al.   TETRAHEDRON

Hindered biaryls by C–H coupling: bisoxazoline-Pd catalysis leading to enantioselective C–H coupling

(2012) Kazuya Yamaguchi et al.   Chemical Science

Catalytic Regioselective Oxidative Coupling of Furan-2-Carbonyls with Simple Arenes

(2012) Nur Asyikin Binte Juwaini et al.   ACS Catalysis

Palladium-Catalyzed Dehydrogenative Cross-Couplings of Benzazoles with Azoles

(2011) Wei Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidative Biaryl Coupling of Thiophenes and Thiazoles with Arylboronic Acids through Palladium Catalysis: Otherwise Difficult C4-Selective CH Arylation Enabled by Boronic Acids

(2011) Sylvia Kirchberg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Oxidative CH/CH Cross-Coupling of Indoles and Pyrroles with Heteroarenes

(2011) Zhen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Decarboxylative CH Bond Arylation of Thiophenes

(2011) Peng Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regiocontrolled aerobic oxidative coupling of indoles and benzene using Pd catalysts with 4,5-diazafluorene ligands

(2011) Alison N. Campbell et al.   CHEMICAL COMMUNICATIONS

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

C–H functionalization logic in total synthesis

(2011) Will R. Gutekunst et al.   CHEMICAL SOCIETY REVIEWS

Oxidative C–H/C–H Coupling of Azine and Indole/Pyrrole Nuclei: Palladium Catalysis and Synthesis of Eudistomin U

(2011) Atsushi D. Yamaguchi et al.   CHEMISTRY LETTERS

Palladium-catalyzed Direct C–H Bond Arylation of Simple Arenes with Aryltrimethylsilanes

(2011) Kenji Funaki et al.   CHEMISTRY LETTERS

Direct Arylation of Benzothiazoles and Benzoxazoles with Aryl Boronic Acids

(2011) Sadananda Ranjit et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Direct Arylations of Azoles with Aryl Silicon and Tin Reagents

(2011) Wei Han et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Progress in Coupling of Two Heteroarenes

(2011) Dongbing Zhao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Desulfitative CH Arylation of Heteroarenes with Sodium Sulfinates

(2011) Bo Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pd/PR3-Catalyzed Cross-Coupling of Aromatic Carboxylic Acids with Electron-Deficient Polyfluoroarenes via Combination of Decarboxylation with sp2C−H Cleavage

(2011) Huaiqing Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Arylation of Polycyclic Aromatic Hydrocarbons through Palladium Catalysis

(2011) Kenji Mochida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-catalyzed desulfitative C–H arylation of azoles with sodium sulfinates

(2011) Ru Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Pd(OAc)2/o-Chloranil/M(OTf)n: A Catalyst for the Direct C–H Arylation of Polycyclic Aromatic Hydrocarbons with Boryl-, Silyl-, and Unfunctionalized Arenes

(2011) Katsuaki Kawasumi et al.   ORGANIC LETTERS

Regioselective Oxidative Coupling Reactions of 3-Substituted Thiophenes with Arylboronic Acids

(2011) Ingo Schnapperelle et al.   ORGANIC LETTERS

Palladium-Catalyzed Oxidative Cross-Coupling between PyridineN-Oxides and Indoles

(2011) Xue Gong et al.   ORGANIC LETTERS

Double C−H Activation: The Palladium-Catalyzed Direct C-Arylation of Xanthines with Arenes

(2011) Chandi C. Malakar et al.   ORGANIC LETTERS

Palladium-Catalyzed Aerobic Dehydrogenative Cross-Coupling of Polyfluoroarenes with Thiophenes: Facile Access to Polyfluoroarene–Thiophene Structure

(2011) Chun-Yang He et al.   ORGANOMETALLICS

Transition metal-catalyzed decarboxylative cross-coupling reactions

(2011) Rui Shang et al.   Science China-Chemistry

Pd(OAc)2-catalyzed cross-coupling of polyfluoroarenes with simple aromatics in imidazolium ionic liquids (ILs) without oxidant and additive and with recycling/reuse of the IL

(2011) Rajesh G. Kalkhambkar et al.   TETRAHEDRON LETTERS

Decarboxylative CH Cross-Coupling of Azoles

(2010) Fengzhi Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Direct CH Arylation and Alkenylation of Heteroarenes with Organosilicon Reagents

(2010) Hitoshi Hachiya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

A Palladium/Copper Bimetallic Catalytic System: Dramatic Improvement for Suzuki-Miyaura-Type Direct CH Arylation of Azoles with Arylboronic Acids

(2010) Bo Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Regioselective Oxidative Arylation of Indoles BearingN-Alkyl Protecting Groups: Dual C−H Functionalization via a Concerted Metalation−Deprotonation Mechanism

(2010) Shathaverdhan Potavathri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Oxidative Cross-Coupling of Perfluoroarenes with Aromatic Heterocycles

(2010) Chun-Yang He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(OAc)2-Catalyzed Oxidative C−H/C−H Cross-Coupling of Electron-Deficient Polyfluoroarenes with Simple Arenes

(2010) Ye Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium(II)-Catalyzed Oxidative C−H/C−H Cross-Coupling of Heteroarenes

(2010) Peihua Xi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Room-Temperature Aromatization of Tetrahydro-β-carbolines by 2-Iodoxybenzoic Acid: Utility in a Total Synthesis of Eudistomin U

(2010) Joseph D. Panarese et al.   ORGANIC LETTERS

Pd-Catalyzed Decarboxylative Arylation of Thiazole, Benzoxazole, and Polyfluorobenzene with Substituted Benzoic Acids

(2010) Kai Xie et al.   ORGANIC LETTERS

Pd(OAc)2-Catalyzed Regioselective Arylation of Indoles with Arylsiloxane in Acidic Medium

(2010) Zunjun Liang et al.   ORGANIC LETTERS

Palladium-Catalyzed Cross-Coupling of Polyfluoroarenes with Simple Arenes

(2010) Hu Li et al.   ORGANIC LETTERS

Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds

(2009) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Palladium-Catalyzed Direct Arylation of Cyclic Enamides with Aryl Silanes by sp2 CH Activation

(2009) Hai Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organotrifluoroborates and Monocoordinated Palladium Complexes as Catalysts—A Perfect Combination for Suzuki–Miyaura Coupling

(2009) Gary A. Molander et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed C3 or C4 Direct Arylation of Heteroaromatic Compounds with Aryl Halides by CH Bond Activation

(2009) Julien Roger et al.   ChemCatChem

Reactivity and regioselectivity of five-membered heterocycles in electrophilic aromatic substitution: A theoretical investigation

(2009) A. Ghomri et al.   JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM

Palladium-Catalyzed Direct Arylation of Electron-Deficient Polyfluoroarenes with Arylboronic Acids

(2009) Ye Wei et al.   ORGANIC LETTERS

Intermolecular Decarboxylative Direct C-3 Arylation of Indoles with Benzoic Acids

(2009) Josep Cornella et al.   ORGANIC LETTERS

Recent advances in the synthesis of (hetero)aryl-substituted heteroarenes via transition metal-catalysed direct (hetero)arylation of heteroarene C–H bonds with aryl halides or pseudohalides, diaryliodonium salts, and potassium aryltrifluoroborates

(2009) Fabio Bellina et al.   TETRAHEDRON

Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations

(2008) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH

Palladium-Catalyzed Direct Arylation of (Hetero)Arenes with Aryl Boronic Acids

(2008) Shang-Dong Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct C–H bond arylation of arenes with aryltin reagents catalysed by palladium complexes

(2008) Hiroshi Kawai et al.   CHEMICAL COMMUNICATIONS

Palladium-catalyzed decarboxylative coupling of aromatic acids with aryl halides or unactivated arenes using microwave heating

(2008) Adelina Voutchkova et al.   CHEMICAL COMMUNICATIONS

Synthesis of Biindolizines through Highly Regioselective Palladium-Catalyzed C−H Functionalization

(2008) Ji-Bao Xia et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed C−H Functionalization of PyridineN-Oxides: Highly Selective Alkenylation and Direct Arylation with Unactivated Arenes

(2008) Seung Hwan Cho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidant-controlled regioselectivity in the oxidative arylation of N-acetylindoles

(2008) Shathaverdhan Potavathri et al.   TETRAHEDRON LETTERS