4.3 Article

Preparation of fluorinated biaryls through direct palladium-catalyzed coupling of polyfluoroarenes with aryltrifluoroborates

Journal

JOURNAL OF FLUORINE CHEMISTRY
Volume 151, Issue -, Pages 50-57

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2013.03.017

Keywords

C-H activation; Palladium; Fluorinated biaryls; Aryltrifluoroborates

Funding

  1. National Natural Science Foundation of China [21072030]
  2. Fuzhou University [022318]
  3. King Abdullah University of Science and Technology

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The direct palladium-catalyzed coupling of polyfluoroarenes with aryltrifluoroborates gave the desired products of fluorinated biaryls in good to excellent yields. A diverse set of important functional groups including methoxy, aldehyde, ester, nitro and halide can be well tolerated in the protocol. (c) 2013 Elsevier B.V. All rights reserved.

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