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Title
Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-04-05
DOI
10.3389/fimmu.2018.00693
References
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Note: Only part of the references are listed.- Secretory autophagy holds the key to lysozyme secretion during bacterial infection of the intestine
- (2018) Elizabeth Delorme-Axford et al. Autophagy
- Secretory autophagy of lysozyme in Paneth cells
- (2018) Shai Bel et al. Autophagy
- Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii -Mediated Inflammation
- (2018) Elise Burger et al. Cell Host & Microbe
- Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models
- (2018) Gyorgy Biczo et al. GASTROENTEROLOGY
- Oxidative stress-elicited autophagosome accumulation contributes to human neuroblastoma SH-SY5Y cell death induced by PBDE-47
- (2017) Cheng Zhang et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- The protection role of Atg16l1 in CD11c + dendritic cells in murine colitis
- (2017) Hong Zhang et al. IMMUNOBIOLOGY
- TREM-1 Inhibition Restores Impaired Autophagy Activity and Reduces Colitis in Mice
- (2017) Tunay Kökten et al. Journal of Crohns & Colitis
- Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis
- (2017) Markus Tschurtschenthaler et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium
- (2017) Yu Matsuzawa-Ishimoto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine
- (2017) Shai Bel et al. SCIENCE
- Guardians of the Gut: Enteric Defensins
- (2017) Sumathi Sankaran-Walters et al. Frontiers in Microbiology
- Intestinal Autophagy and Its Pharmacological Control in Inflammatory Bowel Disease
- (2017) Ping Ke et al. Frontiers in Immunology
- Intestinal Epithelial Cell Endoplasmic Reticulum Stress and Inflammatory Bowel Disease Pathogenesis: An Update Review
- (2017) Xiaoshi Ma et al. Frontiers in Immunology
- The roles of macrophage autophagy in atherosclerosis
- (2016) Bo-zong Shao et al. ACTA PHARMACOLOGICA SINICA
- Chaperone mediated autophagy in aging: Starve to prosper
- (2016) Maria Xilouri et al. AGEING RESEARCH REVIEWS
- 14,15-Epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagy
- (2016) Yunxiao Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis
- (2016) Hae-Youn Lee et al. Autophagy
- Lysosomal signaling in control of degradation pathways
- (2016) Lukas A Huber et al. CURRENT OPINION IN CELL BIOLOGY
- Links of Autophagy Dysfunction to Inflammatory Bowel Disease Onset
- (2016) Faris El-Khider et al. DIGESTIVE DISEASES
- Mammalian autophagy and the plasma membrane
- (2016) Mariana Pavel et al. FEBS Journal
- Mitochondrial ROS regulation of proliferating cells
- (2016) Lauren Diebold et al. FREE RADICAL BIOLOGY AND MEDICINE
- Identification of a fluorescent small-molecule enhancer for therapeutic autophagy in colorectal cancer by targeting mitochondrial protein translocase TIM44
- (2016) Yinghui Huang et al. GUT
- NOD2 induces autophagy to control AIEC bacteria infectiveness in intestinal epithelial cells
- (2016) Anna Negroni et al. INFLAMMATION RESEARCH
- Autophagy in leukocytes and other cells: mechanisms, subsystem organization, selectivity, and links to innate immunity
- (2016) Vojo Deretic JOURNAL OF LEUKOCYTE BIOLOGY
- Regulation of human intestinal T-cell responses by type 1 interferon-STAT1 signaling is disrupted in inflammatory bowel disease
- (2016) E M Giles et al. Mucosal Immunology
- Erratum: Corrigendum: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells
- (2016) Jennifer Martinez et al. NATURE
- The intestinal epithelial barrier: a therapeutic target?
- (2016) Matthew A. Odenwald et al. Nature Reviews Gastroenterology & Hepatology
- IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease
- (2016) Milena J. Tosiek et al. Nature Communications
- The Mucosal Immune System and Its Regulation by Autophagy
- (2016) Agnieszka M. Kabat et al. Frontiers in Immunology
- VDR/vitamin D receptor regulates autophagic activity through ATG16L1
- (2015) Jun Sun Autophagy
- Role of Autophagy in the Maintenance of Intestinal Homeostasis
- (2015) Leigh A. Baxt et al. GASTROENTEROLOGY
- Impaired Autophagy Induces Chronic Atrophic Pancreatitis in Mice via Sex- and Nutrition-Dependent Processes
- (2015) Kalliope N. Diakopoulos et al. GASTROENTEROLOGY
- Understanding inflammatory bowel disease via immunogenetics
- (2015) Katrina M. de Lange et al. JOURNAL OF AUTOIMMUNITY
- Defective macrophage handling ofEscherichia coliin Crohn's disease
- (2015) TR Elliott et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Organelle-Specific Initiation of Autophagy
- (2015) Valentina Sica et al. MOLECULAR CELL
- Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
- (2015) Jimmy Z Liu et al. NATURE GENETICS
- LRRK2 and Nod2 promote lysozyme sorting in Paneth cells
- (2015) Juliana D B Rocha et al. NATURE IMMUNOLOGY
- Commensal bacteria direct selective cargo sorting to promote symbiosis
- (2015) Qin Zhang et al. NATURE IMMUNOLOGY
- Mo1778 Abnormal Activation of Crinophagy in Crohn's Disease Paneth Cells
- (2015) Elodie Thachil et al. GASTROENTEROLOGY
- Targeting Mitochondria-Derived Reactive Oxygen Species to Reduce Epithelial Barrier Dysfunction and Colitis
- (2014) Arthur Wang et al. AMERICAN JOURNAL OF PATHOLOGY
- Deficient autophagy unravels the ROS paradox in chronic granulomatous disease
- (2014) Frank L van de Veerdonk et al. Autophagy
- Autophagy, viruses, and intestinal immunity
- (2014) Elisabeth Kernbauer et al. CURRENT OPINION IN GASTROENTEROLOGY
- The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead
- (2014) Aleksandar D. Kostic et al. GASTROENTEROLOGY
- Intestinal epithelial vitamin D receptor deletion leads to defective autophagy in colitis
- (2014) Shaoping Wu et al. GUT
- Chronic Oxidative Stress Increases Growth and Tumorigenic Potential of MCF-7 Breast Cancer Cells
- (2014) Prathap Kumar S. Mahalingaiah et al. PLoS One
- Essential role for autophagy during invariant NKT cell development
- (2014) Mariolina Salio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunopathology of inflammatory bowel disease
- (2014) Kori L Wallace WORLD JOURNAL OF GASTROENTEROLOGY
- Intestinal barrier in inflammatory bowel disease
- (2014) Lena Antoni WORLD JOURNAL OF GASTROENTEROLOGY
- Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation
- (2013) Bo Liu et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- DAMPs and autophagy
- (2013) Qiuhong Zhang et al. Autophagy
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- (2013) Sandra Cabrera et al. Autophagy
- ER stress-induced cell death mechanisms
- (2013) Renata Sano et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Oxidative Stress and Pathophysiology of Ischemic Stroke: Novel Therapeutic Opportunities
- (2013) Ramon Rodrigo et al. CNS & Neurological Disorders-Drug Targets
- Inflammatory bowel disease epidemiology
- (2013) Johan Burisch et al. CURRENT OPINION IN GASTROENTEROLOGY
- Enteroendocrine cells in gastrointestinal pathophysiology
- (2013) Elizabeth Harrison et al. CURRENT OPINION IN PHARMACOLOGY
- ATG16L1Crohn's disease risk stresses the endoplasmic reticulum of Paneth cells
- (2013) Arthur Kaser et al. GUT
- Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohn's disease
- (2013) J Jasper Deuring et al. GUT
- Serum calprotectin as a biomarker for Crohn's disease
- (2013) M.-A. Meuwis et al. Journal of Crohns & Colitis
- Paneth cells as a site of origin for intestinal inflammation
- (2013) Timon E. Adolph et al. NATURE
- The unfolded protein response and gastrointestinal disease
- (2013) Arthur Kaser et al. Seminars in Immunopathology
- Interplay of autophagy and innate immunity in Crohn's disease: A key immunobiologic feature
- (2013) Györgyi Műzes WORLD JOURNAL OF GASTROENTEROLOGY
- Intestinal Epithelium and Autophagy: Partners in Gut Homeostasis
- (2013) Sarron Randall-Demllo et al. Frontiers in Immunology
- Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response
- (2012) Pierre Lapaquette et al. CELLULAR MICROBIOLOGY
- Interferon-gamma signals via an ERK1/2-ARF6 pathway to promote bacterial internalization by gut epithelia
- (2012) David Smyth et al. CELLULAR MICROBIOLOGY
- Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury
- (2012) Xiucui Ma et al. CIRCULATION
- Common alleles that influence autophagy and the risk for inflammatory bowel disease
- (2012) Agnès Gardet et al. CURRENT OPINION IN IMMUNOLOGY
- ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth
- (2012) Lori S. Hart et al. JOURNAL OF CLINICAL INVESTIGATION
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death
- (2012) E. C. Cheung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vitamin D Inhibits Human Immunodeficiency Virus Type 1 and Mycobacterium tuberculosis Infection in Macrophages through the Induction of Autophagy
- (2012) Grant R. Campbell et al. PLoS Pathogens
- EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages
- (2011) Wei Li et al. BIOCHEMICAL PHARMACOLOGY
- Role of mucus layers in gut infection and inflammation
- (2011) Gunnar C Hansson CURRENT OPINION IN MICROBIOLOGY
- Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
- (2011) Nicolas Dupont et al. EMBO JOURNAL
- Common variation in the vitamin D receptor gene and risk of inflammatory bowel disease in an Irish case–control study
- (2011) David J. Hughes et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Antimicrobial peptides important in innate immunity
- (2011) Andreas Cederlund et al. FEBS Journal
- Recent Insights Into the Genetics of Inflammatory Bowel Disease
- (2011) Judy H. Cho et al. GASTROENTEROLOGY
- Higher Predicted Vitamin D Status Is Associated With Reduced Risk of Crohn's Disease
- (2011) Ashwin N. Ananthakrishnan et al. GASTROENTEROLOGY
- Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review
- (2011) Natalie A. Molodecky et al. GASTROENTEROLOGY
- Sweet-talk: role of host glycosylation in bacterial pathogenesis of the gastrointestinal tract
- (2011) A. P. Moran et al. GUT
- Crohn's disease: NOD2, autophagy and ER stress converge
- (2011) T. Fritz et al. GUT
- Epithelial barrier: an interface for the cross-communication between gut flora and immune system
- (2011) Yoshiyuki Goto et al. IMMUNOLOGICAL REVIEWS
- Altered O-glycosylation profile of MUC2 mucin occurs in active ulcerative colitis and is associated with increased inflammation
- (2011) Jessica M. Holmn Larsson et al. INFLAMMATORY BOWEL DISEASES
- Commensal and Probiotic Bacteria Influence Intestinal Barrier Function and Susceptibility to Colitis in Nod1−/−;Nod2−/− Mice
- (2011) Jane M.M. Natividad et al. INFLAMMATORY BOWEL DISEASES
- Autophagy in immunity and inflammation
- (2011) Beth Levine et al. NATURE
- Genetics and pathogenesis of inflammatory bowel disease
- (2011) Bernard Khor et al. NATURE
- The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
- (2011) Maria M. Mihaylova et al. NATURE CELL BIOLOGY
- Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
- (2011) Charles L. Bevins et al. NATURE REVIEWS MICROBIOLOGY
- Mucin dynamics and enteric pathogens
- (2011) Michael A. McGuckin et al. NATURE REVIEWS MICROBIOLOGY
- Association of a common vitamin D-binding protein polymorphism with inflammatory bowel disease
- (2011) Jyrki J. Eloranta et al. Pharmacogenetics and Genomics
- The Inflammatory Bowel Diseases and Ambient Air Pollution: A Novel Association
- (2010) Gilaad G Kaplan et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- ER stress and the unfolded protein response in intestinal inflammation
- (2010) Michael A. McGuckin et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Inflammatory Bowel Disease
- (2010) Arthur Kaser et al. Annual Review of Immunology
- Homeostasis and Inflammation in the Intestine
- (2010) Wendy S. Garrett et al. CELL
- Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine
- (2010) Ken Cadwell et al. CELL
- Autophagy and Crohns Disease: At the Crossroads of Infection, Inflammation, Immunity, and Cancer
- (2010) P. Brest et al. CURRENT MOLECULAR MEDICINE
- Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis
- (2010) Arthur Kaser et al. CURRENT OPINION IN GASTROENTEROLOGY
- Paneth cells and innate mucosal immunity
- (2010) André J Ouellette CURRENT OPINION IN GASTROENTEROLOGY
- The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease
- (2010) Susanne Billmann-Born et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Vitamin D, NOD2, autophagy and Crohn’s disease
- (2010) Mark Verway et al. Expert Review of Clinical Immunology
- Crohn's Disease Susceptibility Gene Interactions, a NOD to the Newcomer ATG16L1
- (2010) Ken Cadwell GASTROENTEROLOGY
- Antibiotic use and inflammatory bowel diseases in childhood
- (2010) A. Hviid et al. GUT
- Ambient air pollution correlates with hospitalizations for inflammatory bowel disease
- (2010) Ashwin N. Ananthakrishnan et al. INFLAMMATORY BOWEL DISEASES
- LRRK2 Is Involved in the IFN- Response and Host Response to Pathogens
- (2010) A. Gardet et al. JOURNAL OF IMMUNOLOGY
- Genome-wide association identifies multiple ulcerative colitis susceptibility loci
- (2010) Dermot P B McGovern et al. NATURE GENETICS
- Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum
- (2010) A. Biswas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epithelial crosstalk at the microbiota-mucosal interface
- (2010) J. M. Wells et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intestinal epithelial cells in inflammatory bowel diseases
- (2010) Giulia Roda WORLD JOURNAL OF GASTROENTEROLOGY
- Identification ofAtg5-dependent transcriptional changes and increases in mitochondrial mass inAtg5-deficient T lymphocytes
- (2009) Linda M. Stephenson et al. Autophagy
- A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn disease
- (2009) Ken Cadwell et al. Autophagy
- Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin
- (2009) Jae-Min Yuk et al. Cell Host & Microbe
- Paneth Cell Development, Differentiation, and Function: New Molecular Cues
- (2009) Thaddeus S. Stappenbeck GASTROENTEROLOGY
- Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches
- (2009) F. Barreau et al. GUT
- Molecular diversity of Escherichia coli in the human gut: New ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohnʼs disease
- (2009) Margarita Martinez-Medina et al. INFLAMMATORY BOWEL DISEASES
- Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate†
- (2009) Kimberley Lewis et al. INFLAMMATORY BOWEL DISEASES
- Mitochondrial dysfunction, persistent oxidative damage, and catalase inhibition in immune cells of naïve and treated Crohnʼs disease
- (2009) Belén Beltrán et al. INFLAMMATORY BOWEL DISEASES
- Vitamin D receptor deletion leads to reduced level of IκBα protein through protein translation, protein–protein interaction, and post-translational modification
- (2009) Shaoping Wu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
- (2009) Kendle M. Maslowski et al. NATURE
- Enteric defensins are essential regulators of intestinal microbial ecology
- (2009) Nita H Salzman et al. NATURE IMMUNOLOGY
- Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
- (2009) Leonardo H Travassos et al. NATURE IMMUNOLOGY
- NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
- (2009) Rachel Cooney et al. NATURE MEDICINE
- Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
- (2009) Michal Caspi Tal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mucosal Immunity: Induction, Dissemination, and Effector Functions
- (2009) P. Brandtzaeg SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Endoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease
- (2009) Arthur Kaser et al. SEMINARS IN IMMUNOLOGY
- XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
- (2008) Arthur Kaser et al. CELL
- Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
- (2008) J Thorburn et al. CELL DEATH AND DIFFERENTIATION
- The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
- (2008) J Li et al. CELL DEATH AND DIFFERENTIATION
- Autophagy Gives a Nod and a Wink to the Inflammasome and Paneth Cells in Crohn's Disease
- (2008) Vojo Deretic et al. DEVELOPMENTAL CELL
- Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
- (2008) Roger Bouillon et al. ENDOCRINE REVIEWS
- Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse
- (2008) M C Arrieta et al. GUT
- A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
- (2008) Ken Cadwell et al. NATURE
- Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
- (2008) Tatsuya Saitoh et al. NATURE
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
- (2008) Steven A McCarroll et al. NATURE GENETICS
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
- (2008) Jeffrey C Barrett et al. NATURE GENETICS
- Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant
- (2008) Petric Kuballa et al. PLoS One
- Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
- (2008) S. Vaishnava et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity
- (2008) John S Adams et al. Nature clinical practice. Endocrinology & metabolism
- Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis
- (2008) Chad K Heazlewood et al. PLOS MEDICINE
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