Antimicrobial peptides important in innate immunity

Leukotriene B4/antimicrobial peptide LL-37 proinflammatory circuits are mediated by BLT1 and FPR2/ALX and are counterregulated by lipoxin A4 and resolvin E1

(2011) Min Wan et al.   FASEB JOURNAL

High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

(2011) Adrian R Martineau et al.   LANCET

LL-37 expression in the skin in systemic lupus erythematosus

(2011) C-L Sun et al.   LUPUS

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1

(2011) Bjoern O. Schroeder et al.   NATURE

Phenylbutyrate Counteracts Shigella Mediated Downregulation of Cathelicidin in Rabbit Lung and Intestinal Epithelia: A Potential Therapeutic Strategy

(2011) Protim Sarker et al.   PLoS One

Real-time attack on single Escherichia coli cells by the human antimicrobial peptide LL-37

(2011) K. A. Sochacki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Severity of Staphylococcus aureus Infection of the Skin Is Associated with Inducibility of Human  -Defensin 3 but Not Human  -Defensin 2

(2010) P. Zanger et al.   INFECTION AND IMMUNITY

Human  -Defensin 3 Inhibits Cell Wall Biosynthesis in Staphylococci

(2010) V. Sass et al.   INFECTION AND IMMUNITY

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

Phenylbutyrate Induces Antimicrobial Peptide Expression

(2009) J. Steinmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bacterial exotoxins downregulate cathelicidin (hCAP-18/LL-37) and human β-defensin 1 (HBD-1) expression in the intestinal epithelial cells

(2008) Krishnendu Chakraborty et al.   CELLULAR MICROBIOLOGY

Antimicrobial peptides and self-DNA in autoimmune skin inflammation

(2008) Michel Gilliet et al.   CURRENT OPINION IN IMMUNOLOGY

The role of the multifunctional peptide LL-37 in host defense

(2008) Ylva Kai-Larsen   Frontiers in Bioscience-Landmark

Structures of Human Host Defense Cathelicidin LL-37 and Its Smallest Antimicrobial Peptide KR-12 in Lipid Micelles

(2008) Guangshun Wang   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil primary granule proteins HBP and HNP1–3 boost bacterial phagocytosis by human and murine macrophages

(2008) Oliver Soehnlein et al.   JOURNAL OF CLINICAL INVESTIGATION

PU.1 and bacterial metabolites regulate the human gene CAMP encoding antimicrobial peptide LL-37 in colon epithelial cells

(2008) Stefan Termén et al.   MOLECULAR IMMUNOLOGY

Did cathelicidins, a family of multifunctional host-defense peptides, arise from a cysteine protease inhibitor?

(2008) Shunyi Zhu   TRENDS IN MICROBIOLOGY

Discovery of six families of fungal defensin-like peptides provides insights into origin and evolution of the CSαβ defensins

(2007) Shunyi Zhu   MOLECULAR IMMUNOLOGY