ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth

Regulation of ER stress-induced macroautophagy by protein kinase C

(2014) Kenjiro Sakaki et al.   Autophagy

Bcl-2 family members: Dual regulators of apoptosis and autophagy

(2014) Beth Levine et al.   Autophagy

A Mouse Model of the Most Aggressive Subgroup of Human Medulloblastoma

(2012) Daisuke Kawauchi et al.   CANCER CELL

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

(2011) Junli Liu et al.   CELL

The role of PML in the control of apoptotic cell fate: a new key player at ER–mitochondria sites

(2011) P Pinton et al.   CELL DEATH AND DIFFERENTIATION

Targeting MYC dependence in cancer by inhibiting BET bromodomains

(2011) J. A. Mertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ammonia-induced autophagy is independent of ULK1/ULK2 kinases

(2011) H. Cheong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer

(2011) J. C. Chan et al.   Science Signaling

Regulation of autophagy by ATF4 in response to severe hypoxia

(2010) T Rzymski et al.   ONCOGENE

PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage

(2010) E Bobrovnikova-Marjon et al.   ONCOGENE

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

The Role of Myc-Induced Protein Synthesis in Cancer

(2009) D. Ruggero   CANCER RESEARCH

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

(2009) Kasper M.A. Rouschop et al.   JOURNAL OF CLINICAL INVESTIGATION

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

(2009) Ping Gao et al.   NATURE

PERK Regulates the Proliferation and Development of Insulin-Secreting Beta-Cell Tumors in the Endocrine Pancreas of Mice

(2009) Sounak Gupta et al.   PLoS One

A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy

(2008) Sandra Turcotte et al.   CANCER CELL

Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis

(2008) Umut Ozcan et al.   MOLECULAR CELL

Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

(2008) Maria Barna et al.   NATURE

N-myc augments death and attenuates protective effects of Bcl-2 in trophically stressed neuroblastoma cells

(2008) A Ushmorov et al.   ONCOGENE

Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium

(2008) Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis

(2007) Kirsteen H. Maclean et al.   JOURNAL OF CLINICAL INVESTIGATION