Lipid and Non-lipid Factors Affecting Macrophage Dysfunction and Inflammation in Atherosclerosis
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Title
Lipid and Non-lipid Factors Affecting Macrophage Dysfunction and Inflammation in Atherosclerosis
Authors
Keywords
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Journal
Frontiers in Physiology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-06-26
DOI
10.3389/fphys.2018.00654
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Note: Only part of the references are listed.- Inhibition of the NLRP3 inflammasome attenuates foam cell formation of THP-1 macrophages by suppressing ox-LDL uptake and promoting cholesterol efflux
- (2018) Liang Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism
- (2018) Graeme I. Lancaster et al. Cell Metabolism
- Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine AtherosclerosisNovelty and Significance
- (2018) Clément Cochain et al. CIRCULATION RESEARCH
- Macrophage metabolism in atherosclerosis
- (2017) Gael F. P. Bories et al. FEBS LETTERS
- By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation
- (2017) Ivan Zanoni et al. IMMUNITY
- NLRP3 inflammasome: Its regulation and involvement in atherosclerosis
- (2017) Zahra Hoseini et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders
- (2017) Hua Jiang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Phagocytosis imprints heterogeneity in tissue-resident macrophages
- (2017) Noelia A-Gonzalez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Oxidized Low-Density Lipoprotein Loading of Macrophages Downregulates TLR-Induced Proinflammatory Responses in a Gene-Specific and Temporal Manner through Transcriptional Control
- (2017) Jenny Jongstra-Bilen et al. JOURNAL OF IMMUNOLOGY
- Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9
- (2017) Jillian P. Rhoads et al. JOURNAL OF IMMUNOLOGY
- Different dynamics of NLRP3 inflammasome-mediated IL‑1β production in GM-CSF– and M-CSF–differentiated human macrophages
- (2017) Marietta Margit Budai et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Interleukin-1 Beta as a Target for Atherosclerosis Therapy
- (2017) Peter Libby JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Novartis trial validates inflammasome as chronic disease driver
- (2017) Cormac Sheridan NATURE BIOTECHNOLOGY
- The NLRP3 inflammasome in acute myocardial infarction
- (2017) Stefano Toldo et al. Nature Reviews Cardiology
- Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
- (2017) Marc S. Sabatine et al. NEW ENGLAND JOURNAL OF MEDICINE
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
- (2017) José J. Fuster et al. SCIENCE
- Context-Dependent Role of Oxidized Lipids and Lipoproteins in Inflammation
- (2017) Yury I. Miller et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Macrophage Immunometabolism: Where Are We (Going)?
- (2017) Jan Van den Bossche et al. TRENDS IN IMMUNOLOGY
- Inflammasome Priming in Sterile Inflammatory Disease
- (2017) Meghana N. Patel et al. TRENDS IN MOLECULAR MEDICINE
- Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
- (2017) Ismail Sergin et al. Nature Communications
- PCSK9 signaling pathways and their potential importance in clinical practice
- (2017) Michał Wiciński et al. EPMA Journal
- Conversion of human M-CSF macrophages into foam cells reduces their proinflammatory responses to classical M1-polarizing activation
- (2016) Rafaela F. da Silva et al. ATHEROSCLEROSIS
- Mass Cytometry: Single Cells, Many Features
- (2016) Matthew H. Spitzer et al. CELL
- Inflammasome-dependent IL-1β release depends upon membrane permeabilisation
- (2016) F Martín-Sánchez et al. CELL DEATH AND DIFFERENTIATION
- Circadian Influence on Metabolism and Inflammation in Atherosclerosis
- (2016) Cameron S. McAlpine et al. CIRCULATION RESEARCH
- Macrophage Phenotype and Function in Different Stages of Atherosclerosis
- (2016) Ira Tabas et al. CIRCULATION RESEARCH
- Abandoning M1/M2 for a Network Model of Macrophage Function
- (2016) Matthias Nahrendorf et al. CIRCULATION RESEARCH
- The time‐of‐day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment
- (2016) Maximilian J Schloss et al. EMBO Molecular Medicine
- Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation
- (2016) Michael J. Primiano et al. JOURNAL OF IMMUNOLOGY
- Nutraceutical therapies for atherosclerosis
- (2016) Joe W. E. Moss et al. Nature Reviews Cardiology
- An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
- (2016) Ivan Zanoni et al. SCIENCE
- Senescent intimal foam cells are deleterious at all stages of atherosclerosis
- (2016) B. G. Childs et al. SCIENCE
- Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
- (2016) Sebastian Zimmer et al. Science Translational Medicine
- Long-term activation of the innate immune system in atherosclerosis
- (2016) Anette Christ et al. SEMINARS IN IMMUNOLOGY
- Mechanism and Regulation of NLRP3 Inflammasome Activation
- (2016) Yuan He et al. TRENDS IN BIOCHEMICAL SCIENCES
- Glutamine Modulates Macrophage Lipotoxicity
- (2016) Li He et al. Nutrients
- Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression – implications for atherosclerosis research
- (2016) Line S. Bisgaard et al. Scientific Reports
- Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells
- (2016) Megan M. Robblee et al. Cell Reports
- NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis
- (2016) Geena Paramel Varghese et al. Journal of the American Heart Association
- HIF-1 and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages
- (2015) A. Tawakol et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Inflammation and Immunity in Diseases of the Arterial Tree: Players and Layers
- (2015) P. Libby et al. CIRCULATION RESEARCH
- Immunometabolism governs dendritic cell and macrophage function
- (2015) Luke A.J. O’Neill et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter
- (2015) Jing Wang et al. NATURE MEDICINE
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- Inflammasomes: mechanism of action, role in disease and therapeutics
- (2015) Haitao Guo et al. NATURE MEDICINE
- Ribosome profiling reveals the what, when, where and how of protein synthesis
- (2015) Gloria A. Brar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Lipid-Induced Epigenomic Changes in Human Macrophages Identify a Coronary Artery Disease-Associated Variant that Regulates PPAP2B Expression through Altered C/EBP-Beta Binding
- (2015) Michael E. Reschen et al. PLoS Genetics
- Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation
- (2015) J. Tang et al. Science Advances
- Induction of Lysosomal Biogenesis in Atherosclerotic Macrophages Can Rescue Lipid-Induced Lysosomal Dysfunction and Downstream Sequelae
- (2014) Roy Emanuel et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Inflammation and its Resolution as Determinants of Acute Coronary Syndromes
- (2014) Peter Libby et al. CIRCULATION RESEARCH
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- Macrophage phenotypes in atherosclerosis
- (2014) Sophie Colin et al. IMMUNOLOGICAL REVIEWS
- P2X7 Receptor Differentially Couples to Distinct Release Pathways for IL-1 in Mouse Macrophage
- (2014) P. Pelegrin et al. JOURNAL OF IMMUNOLOGY
- PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes
- (2014) Rajiv Lochan Tiwari et al. JOURNAL OF LIPID RESEARCH
- Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- Macrophage subsets in atherosclerosis
- (2014) Giulia Chinetti-Gbaguidi et al. Nature Reviews Cardiology
- 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon
- (2014) A. Reboldi et al. SCIENCE
- Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation
- (2014) Fränze Progatzky et al. Nature Communications
- Cytokine Secretion in Macrophages: SNAREs, Rabs, and Membrane Trafficking
- (2014) Rachael Zoe Murray et al. Frontiers in Immunology
- Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice
- (2013) Marit Westerterp et al. CIRCULATION RESEARCH
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- Cardioprotective functions of HDLs
- (2013) Kerry-Anne Rye et al. JOURNAL OF LIPID RESEARCH
- High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3
- (2013) Dominic De Nardo et al. NATURE IMMUNOLOGY
- CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
- (2013) Frederick J Sheedy et al. NATURE IMMUNOLOGY
- Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis
- (2013) Stefan Freigang et al. NATURE IMMUNOLOGY
- Oxidized Low Density Lipoprotein Induced Caspase-1 Mediated Pyroptotic Cell Death in Macrophages: Implication in Lesion Instability?
- (2013) Jing Lin et al. PLoS One
- Polyoxygenated Cholesterol Ester Hydroperoxide Activates TLR4 and SYK Dependent Signaling in Macrophages
- (2013) Soo-Ho Choi et al. PLoS One
- A Role of RIP3-Mediated Macrophage Necrosis in Atherosclerosis Development
- (2013) Juan Lin et al. Cell Reports
- Cholesterol Accumulation Regulates Expression of Macrophage Proteins Implicated in Proteolysis and Complement Activation
- (2012) Masashi Suzuki et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice
- (2012) Fumitake Usui et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses
- (2012) Nathanael J. Spann et al. CELL
- High-density lipoproteins suppress chemokine expression and proliferation in human vascular smooth muscle cells
- (2012) Emiel P. C. van der Vorst et al. FASEB JOURNAL
- Defining GM-CSF- and Macrophage-CSF-Dependent Macrophage Responses by In Vitro Models
- (2012) D. C. Lacey et al. JOURNAL OF IMMUNOLOGY
- A new era for quantifying HDL and cardiovascular risk?
- (2012) Jay W Heinecke NATURE MEDICINE
- Molecular Etiology of Atherogenesis – In Vitro Induction of Lipidosis in Macrophages with a New LDL Model
- (2012) Luis M. B. B. Estronca et al. PLoS One
- ER stress activates the NLRP3 inflammasome via an UPR-independent pathway
- (2012) P Menu et al. Cell Death & Disease
- Serum starvation: caveat emptor
- (2011) Sergej Pirkmajer et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Regulation of Lipid Droplet Cholesterol Efflux From Macrophage Foam Cells
- (2011) Mireille Ouimet et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase
- (2011) Mireille Ouimet et al. Cell Metabolism
- Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity
- (2011) Yury I. Miller et al. CIRCULATION RESEARCH
- Activating Transcription Factor 1 Directs Mhem Atheroprotective Macrophages Through Coordinated Iron Handling and Foam Cell Protection
- (2011) Joseph J. Boyle et al. CIRCULATION RESEARCH
- Oxidative Modification of Lipoproteins: Mechanisms, Role in Inflammation and Potential Clinical Applications in Cardiovascular Disease
- (2011) Sotirios Tsimikas et al. CURRENT PHARMACEUTICAL DESIGN
- OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases
- (2011) Ku-Chung Chen et al. FASEB JOURNAL
- Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2
- (2011) Alexandra Kadl et al. FREE RADICAL BIOLOGY AND MEDICINE
- Electrospray MS/MS reveals extensive and nonspecific oxidation of cholesterol esters in human peripheral vascular lesions
- (2011) Patrick M. Hutchins et al. JOURNAL OF LIPID RESEARCH
- 7-Ketocholesterol is Not Cytotoxic to U937 Cells When Incorporated into Acetylated Low Density Lipoprotein
- (2011) Lucy D. Rutherford et al. LIPIDS
- Progress and challenges in translating the biology of atherosclerosis
- (2011) Peter Libby et al. NATURE
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- Inflammasome activation and IL-1β and IL-18 processing during infection
- (2011) Frank L. van de Veerdonk et al. TRENDS IN IMMUNOLOGY
- Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome
- (2011) P Menu et al. Cell Death & Disease
- High-Density Lipoproteins Suppress Chemokines and Chemokine Receptors In Vitro and In Vivo
- (2010) Christina A. Bursill et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Myeloid Differentiation Primary Response Protein 88 Couples Reverse Cholesterol Transport to Inflammation
- (2010) Kathleen A. Smoak et al. Cell Metabolism
- High-Density Lipoprotein Suppresses the Type I Interferon Response, a Family of Potent Antiviral Immunoregulators, in Macrophages Challenged With Lipopolysaccharide
- (2010) Masashi Suzuki et al. CIRCULATION
- Low Doses of Lipopolysaccharide and Minimally Oxidized Low-Density Lipoprotein Cooperatively Activate Macrophages via Nuclear Factor κB and Activator Protein-1
- (2010) Philipp Wiesner et al. CIRCULATION RESEARCH
- Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2
- (2010) Alexandra Kadl et al. CIRCULATION RESEARCH
- The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis
- (2010) Ira Tabas CIRCULATION RESEARCH
- Oxidized Phospholipids Are More Potent Antagonists of Lipopolysaccharide than Inducers of Inflammation
- (2010) O. V. Oskolkova et al. JOURNAL OF IMMUNOLOGY
- 7-Ketocholesteryl-9-carboxynonanoate induced nuclear factor-kappa B activation in J774A.1 macrophages
- (2010) Zhenyu Huang et al. LIFE SCIENCES
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Endoplasmic reticulum stress and atherosclerosis
- (2010) Gökhan S Hotamisligil NATURE MEDICINE
- The core-aldehyde 9-oxononanoyl cholesterol increases the level of transforming growth factor β1-specific receptors on promonocytic U937 cell membranes
- (2009) Simona Gargiulo et al. AGING CELL
- Oxidized LDL: Diversity, Patterns of Recognition, and Pathophysiology
- (2009) Irena Levitan et al. ANTIOXIDANTS & REDOX SIGNALING
- Oxidized Phospholipid Inhibition of LPS-Signaling
- (2009) Clett Erridge ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Mechanisms of interleukin-1β release
- (2009) Claudia Eder IMMUNOBIOLOGY
- Late Endosome/Lysosome-Localized Rab7b Suppresses TLR9-Initiated Proinflammatory Cytokine and Type I IFN Production in Macrophages
- (2009) M. Yao et al. JOURNAL OF IMMUNOLOGY
- GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling
- (2009) Andrew J. Fleetwood et al. JOURNAL OF LEUKOCYTE BIOLOGY
- CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
- (2009) Cameron R Stewart et al. NATURE IMMUNOLOGY
- A circadian clock in macrophages controls inflammatory immune responses
- (2009) Maren Keller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Heterogeneity of Human Macrophages in Culture and in Atherosclerotic Plaques
- (2008) Stephen W. Waldo et al. AMERICAN JOURNAL OF PATHOLOGY
- Multi-Hit Inhibition of Circulating and Cell-Associated Components of the Toll-Like Receptor 4 Pathway by Oxidized Phospholipids
- (2008) Elena von Schlieffen et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Differential requirement for the activation of the inflammasome for processing and release of IL-1 in monocytes and macrophages
- (2008) M. G. Netea et al. BLOOD
- The Lysosomal Transmembrane Protein 9B Regulates the Activity of Inflammatory Signaling Pathways
- (2008) Francis Dodeller et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cholesteryl Ester Hydroperoxides Are Biologically Active Components of Minimally Oxidized Low Density Lipoprotein
- (2008) Richard Harkewicz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of dysfunctional HDL in atherosclerosis
- (2008) Mohamad Navab et al. JOURNAL OF LIPID RESEARCH
- Lysosomal Cholesterol Accumulation Inhibits Subsequent Hydrolysis of Lipoprotein Cholesteryl Ester
- (2008) W. Gray Jerome et al. MICROSCOPY AND MICROANALYSIS
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