Oxidized Low-Density Lipoprotein Loading of Macrophages Downregulates TLR-Induced Proinflammatory Responses in a Gene-Specific and Temporal Manner through Transcriptional Control

Rspo2 suppresses CD36-mediated apoptosis in oxidized low density lipoprotein-induced macrophages

(2016) Hui Yan et al.   Molecular Medicine Reports

Transcription Factors NRF2 and NF-κB Are Coordinated Effectors of the Rho Family, GTP-binding Protein RAC1 during Inflammation

(2014) Antonio Cuadrado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Protein Associations Define Two Phases of IL-1  Transcriptional Activation

(2014) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis

(2014) Jonathan D. Brown et al.   MOLECULAR CELL

25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon

(2014) A. Reboldi et al.   SCIENCE

Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis

(2013) Anna M. Lundberg et al.   CARDIOVASCULAR RESEARCH

Redox activation of Nrf2 & NF-κB: A double end sword?

(2013) Mabel Buelna-Chontal et al.   CELLULAR SIGNALLING

OxLDL-induced IL-1beta secretion promoting foam cells formation was mainly via CD36 mediated ROS production leading to NLRP3 inflammasome activation

(2013) Weiwei Liu et al.   INFLAMMATION RESEARCH

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

(2013) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages

(2013) Peng Lv et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Myeloid Deletion of Nuclear Factor Erythroid 2−Related Factor 2 Increases Atherosclerosis and Liver Injury

(2012) Alan R. Collins et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Oxidized low-density lipoprotein induces secretion of interleukin-1β by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation

(2012) Yugang Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

(2012) Nathanael J. Spann et al.   CELL

The effect of oxidized low density lipoprotein (oxLDL)-induced heme oxygenase-1 on LPS-induced inflammation in RAW 264.7 macrophage cells

(2012) Kyoung-jin Min et al.   CELLULAR SIGNALLING

ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol–induced lipid body formation

(2012) Elizabeth S. Gold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Antioxidant signaling via Nrf2 counteracts lipopolysaccharide-mediated inflammatory responses in foam cell macrophages

(2011) Anne-Marie Kuhn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human Oxidation-Specific Antibodies Reduce Foam Cell Formation and Atherosclerosis Progression

(2011) Sotirios Tsimikas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Toll-Like Receptors, Their Ligands, and Atherosclerosis

(2011) Conrad P. Hodgkinson et al.   TheScientificWorldJOURNAL

NF-E2–Related Factor 2 Promotes Atherosclerosis by Effects on Plasma Lipoproteins and Cholesterol Transport That Overshadow Antioxidant Protection

(2010) Berenice Barajas et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Deciphering the complexity of Toll-like receptor signaling

(2010) Renato Ostuni et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Low Doses of Lipopolysaccharide and Minimally Oxidized Low-Density Lipoprotein Cooperatively Activate Macrophages via Nuclear Factor κB and Activator Protein-1

(2010) Philipp Wiesner et al.   CIRCULATION RESEARCH

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

ATF3, a Hub of the Cellular Adaptive-Response Network, in the Pathogenesis of Diseases: Is Modulation of Inflammation a Unifying Component?

(2010) TSONWIN HAI et al.   GENE EXPRESSION

Peroxisome Proliferator-activated Receptor γ Negatively Regulates IFN-β Production in Toll-like Receptor (TLR) 3- and TLR4-stimulated Macrophages by Preventing Interferon Regulatory Factor 3 Binding to the IFN-β Promoter

(2010) Wei Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic cells pulsed with malondialdehyde modified low density lipoprotein aggravate atherosclerosis in Apoe−/− mice

(2009) Charlotta Hjerpe et al.   ATHEROSCLEROSIS

Epigenetic regulation of dendritic cell differentiation and function by oxidized phospholipids

(2009) S. Bluml et al.   BLOOD

Vaccination using oxidized low-density lipoprotein-pulsed dendritic cells reduces atherosclerosis in LDL receptor-deficient mice

(2009) Kim L.L. Habets et al.   CARDIOVASCULAR RESEARCH

Macrophage Apoptosis Exerts Divergent Effects on Atherogenesis as a Function of Lesion Stage

(2009) Emmanuel L. Gautier et al.   CIRCULATION

Resident Intimal Dendritic Cells Accumulate Lipid and Contribute to the Initiation of Atherosclerosis

(2009) Kim E. Paulson et al.   CIRCULATION RESEARCH

Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease

(2009) D. Pons et al.   EUROPEAN HEART JOURNAL

GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions

(2009) Su-Ning Zhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK

(2008) Guang-Hui Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival

(2008) L. Landsman et al.   BLOOD

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Impact of macrophage toll-like receptor 4 deficiency on macrophage infiltration into adipose tissue and the artery wall in mice

(2008) K. R. Coenen et al.   DIABETOLOGIA

NF-κB dictates the degradation pathway of IκBα

(2008) Erika Mathes et al.   EMBO JOURNAL

Mechanisms and consequences of macrophage apoptosis in atherosclerosis

(2008) Tracie Seimon et al.   JOURNAL OF LIPID RESEARCH

The LDL modification hypothesis of atherogenesis: an update

(2008) Daniel Steinberg   JOURNAL OF LIPID RESEARCH

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY