Oxidative stress, a common molecular pathway for kidney disease: Role of the redox enzyme p66Shc

Deficit of p66ShcA restores redox-sensitive stress response program in cisplatin-induced acute kidney injury

(2013) Rungwasee Rattanavich et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

(2013) Ming Zhan et al.   KIDNEY INTERNATIONAL

Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc

(2013) I. Arany et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Reactive oxygen species induced by p66Shc longevity protein mediate nongenomic androgen action via tyrosine phosphorylation signaling to enhance tumorigenicity of prostate cancer cells

(2012) Suresh Veeramani et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial dysfunction accounts for aldosterone-induced epithelial-to-mesenchymal transition of renal proximal tubular epithelial cells

(2012) Yanggang Yuan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox regulation of mitochondrial biogenesis

(2012) Claude A. Piantadosi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress, anti-oxidant therapies and chronic kidney disease

(2012) DAVID M SMALL et al.   NEPHROLOGY

Smoking Is a Risk Factor for Graft Failure and Mortality after Renal Transplantation

(2011) Pramod K. Agarwal et al.   AMERICAN JOURNAL OF NEPHROLOGY

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Repression of P66Shc Expression by SIRT1 Contributes to the Prevention of Hyperglycemia-Induced Endothelial Dysfunction

(2011) Shuang Zhou et al.   CIRCULATION RESEARCH

Extracellular matrix calcification in chronic kidney disease

(2011) Nigel D Toussaint   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Molecular mechanisms and physiologic functions of mitochondrial dynamics

(2011) H. Otera et al.   JOURNAL OF BIOCHEMISTRY

Sirtuins: Molecular Traffic Lights in the Crossroad of Oxidative Stress, Chromatin Remodeling, and Transcription

(2011) Ramkumar Rajendran et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Smoking is a risk factor in the progression to kidney failure

(2011) Stein I. Hallan et al.   KIDNEY INTERNATIONAL

Biomarkers in chronic kidney disease: a review

(2011) Robert G. Fassett et al.   KIDNEY INTERNATIONAL

Resveratrol protects against hyperglycemia-induced oxidative damage to mitochondria by activating SIRT1 in rat mesangial cells

(2011) Ying Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

p66Shc, a multifaceted protein linking Erk signalling, glucose metabolism, and oxidative stress

(2011) Annalisa Natalicchio et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Mitochondrial longevity pathways

(2010) Anna Raffaello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cisplatin induces apoptosis through the ERK–p66shc pathway in renal proximal tubule cells

(2010) Jeb S. Clark et al.   CANCER LETTERS

P66shc and its downstream Eps8 and Rac1 proteins are upregulated in esophageal cancers

(2010) Muneesa Bashir et al.   Cell Communication and Signaling

Transcriptional Control of Mitochondrial Biogenesis and Function

(2009) M. Benjamin Hock et al.   Annual Review of Physiology

Inhibition of p66ShcA Longevity Gene Rescues Podocytes from HIV-1-induced Oxidative Stress and Apoptosis

(2009) Mohammad Husain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease

(2009) Hervé Acloque et al.   JOURNAL OF CLINICAL INVESTIGATION

New Insights into Epithelial-Mesenchymal Transition in Kidney Fibrosis

(2009) Y. Liu   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitochondrial Dynamics in Mammalian Health and Disease

(2009) Marc Liesa et al.   PHYSIOLOGICAL REVIEWS

The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity

(2008) F. Finetti et al.   BLOOD

A novel role of Shc adaptor proteins in steroid hormone-regulated cancers

(2008) Syed Mahfuzul Alam et al.   ENDOCRINE-RELATED CANCER

p66shcInhibits Pro-survival Epidermal Growth Factor Receptor/ERK Signaling during Severe Oxidative Stress in Mouse Renal Proximal Tubule Cells

(2008) Istvan Arany et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic Gene Silencing Delivered by a Chemically Modified Small Interfering RNA against Mutant SOD1 Slows Amyotrophic Lateral Sclerosis Progression

(2008) Hongyan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p66Shc-generated Oxidative Signal Promotes Fat Accumulation

(2008) Ina Berniakovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

Role of the life span determinant P66shcA in ethanol-induced liver damage

(2008) Osvaldo R Koch et al.   LABORATORY INVESTIGATION

Obesity and hypertension have differing oxidant handling molecular pathways in age-related chronic kidney disease

(2008) C.J. Percy et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Smoking: A Risk Factor for Progression of Chronic Kidney Disease and for Cardiovascular Morbidity and Mortality in Renal Patients Absence of Evidence or Evidence of Absence?

(2007) S. R. Orth et al.   Clinical Journal of the American Society of Nephrology

Potentiation of reactive oxygen species is a marker for synergistic cytotoxicity of MS-275 and 5-azacytidine in leukemic cells

(2007) Shan Gao et al.   LEUKEMIA RESEARCH