The nuclear melatonin receptor RORαis a novel endogenous defender against myocardial ischemia/reperfusion injury

Vitamin D Receptor Activation Protects Against Myocardial Reperfusion Injury Through Inhibition of Apoptosis and Modulation of Autophagy

(2015) Tianbao Yao et al.   ANTIOXIDANTS & REDOX SIGNALING

Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells

(2015) Fabio R. Santori et al.   Cell Metabolism

Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice

(2015) José A. García et al.   FASEB JOURNAL

Photoperiodic regulation of nuclear melatonin receptor RORα in lymphoid organs of a tropical rodent Funambulus pennanti: Role in seasonal oxidative stress

(2015) Sameer Gupta et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Doxorubicin resistance in breast cancer is driven by light at night-induced disruption of the circadian melatonin signal

(2015) Shulin Xiang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin inhibits autophagy and endoplasmic reticulum stress in mice with carbon tetrachloride-induced fibrosis

(2015) Beatriz San-Miguel et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

Dental pulp-derived stem cell conditioned medium reduces cardiac injury following ischemia-reperfusion

(2015) Satoshi Yamaguchi et al.   Scientific Reports

Vagal modulation of high mobility group box-1 protein mediates electroacupuncture-induced cardioprotection in ischemia-reperfusion injury

(2015) Juan Zhang et al.   Scientific Reports

bFGF regulates autophagy and ubiquitinated protein accumulation induced by myocardial ischemia/reperfusion via the activation of the PI3K/Akt/mTOR pathway

(2015) Zhou-Guang Wang et al.   Scientific Reports

Traditional Chinese Medication Qiliqiangxin attenuates cardiac remodeling after acute myocardial infarction in mice

(2015) Lichan Tao et al.   Scientific Reports

Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease

(2015) Lihua Jin et al.   Scientific Reports

Therapeutic window of globular adiponectin against cerebral ischemia in diabetic mice: the role of dynamic alteration of adiponectin/adiponectin receptor expression

(2015) Wenying Song et al.   Scientific Reports

LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling

(2015) Ayaka Ito et al.   eLife

ROR nuclear receptors: structures, related diseases and drug discovery

(2014) Yan Zhang et al.   ACTA PHARMACOLOGICA SINICA

RORα Decreases Oxidative Stress Through the Induction of SOD2 and GPx1 Expression and Thereby Protects Against Nonalcoholic Steatohepatitis in Mice

(2014) Yong-Hyun Han et al.   ANTIOXIDANTS & REDOX SIGNALING

Cracking the survival code

(2014) Jens Füllgrabe et al.   Autophagy

The Therapeutic Potential of Nuclear Receptor Modulators for Treatment of Metabolic Disorders: PPARγ, RORs, and Rev-erbs

(2014) David P. Marciano et al.   Cell Metabolism

Melatonin Inhibits mTOR-Dependent Autophagy during Liver Ischemia/Reperfusion

(2014) Jung-Woo Kang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Short-Term Disruption of Diurnal Rhythms After Murine Myocardial Infarction Adversely Affects Long-Term Myocardial Structure and Function

(2014) Faisal J. Alibhai et al.   CIRCULATION RESEARCH

Activation of Liver-X-Receptor α But Not Liver-X-Receptor β Protects Against Myocardial Ischemia/Reperfusion Injury

(2014) Qing He et al.   Circulation-Heart Failure

RORα suppresses proliferation of vascular smooth muscle cells through activation of AMP-activated protein kinase

(2014) Eun-Jin Kim et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Inhibition of Autophagy Contributes to Melatonin-Mediated Neuroprotection Against Transient Focal Cerebral Ischemia in Rats

(2014) Yongqiu Zheng et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells

(2014) Yunkyung Hong et al.   JOURNAL OF PINEAL RESEARCH

Melatonin receptor-mediated protection against myocardial ischemia/reperfusion injury: role of SIRT1

(2014) Liming Yu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin-mediatedβ-catenin activation protects neuron cells against prion protein-induced neurotoxicity

(2014) Jae-Kyo Jeong et al.   JOURNAL OF PINEAL RESEARCH

Insights Into Echo-Attenuated Plaques, Echolucent Plaques, and Plaques With Spotty Calcification

(2014) Jun Pu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

REV-ERB and ROR nuclear receptors as drug targets

(2014) Douglas J. Kojetin et al.   NATURE REVIEWS DRUG DISCOVERY

Baicalin Protects the Cardiomyocytes from ER Stress-Induced Apoptosis: Inhibition of CHOP through Induction of Endothelial Nitric Oxide Synthase

(2014) Mingzhi Shen et al.   PLoS One

JAK2/STAT3 activation by melatonin attenuates the mitochondrial oxidative damage induced by myocardial ischemia/reperfusion injury

(2013) Yang Yang et al.   JOURNAL OF PINEAL RESEARCH

The role of melatonin in the cells of the innate immunity: a review

(2013) Juan R. Calvo et al.   JOURNAL OF PINEAL RESEARCH

Myocardial Ablation of G Protein–Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway

(2013) Qian Fan et al.   PLoS One

H2O2-responsive molecularly engineered polymer nanoparticles as ischemia/reperfusion-targeted nanotherapeutic agents

(2013) Dongwon Lee et al.   Scientific Reports

Essential Role of Caveolin-3 in Adiponectin Signalsome Formation and Adiponectin Cardioprotection

(2012) Yajing Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impaired Autophagosome Clearance Contributes to Cardiomyocyte Death in Ischemia/Reperfusion Injury

(2012) Xiucui Ma et al.   CIRCULATION

Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury

(2012) Jun Pu et al.   EUROPEAN HEART JOURNAL

RORα, a Potential Tumor Suppressor and Therapeutic Target of Breast Cancer

(2012) Jun Du et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysis of the daily changes of melatonin receptors in the rat liver

(2012) Carmen Venegas et al.   JOURNAL OF PINEAL RESEARCH

Melatonin membrane receptors in peripheral tissues: Distribution and functions

(2012) Radomir M. Slominski et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Is retinoic acid-related orphan receptor-alpha (RORA) a target for gene–environment interactions contributing to autism?

(2012) Valerie W. Hu   NEUROTOXICOLOGY

Expression of Circadian Clock and Melatonin Receptors within Cultured Rat Cardiomyocytes

(2010) Rodrigo A. Peliciari-Garcia et al.   CHRONOBIOLOGY INTERNATIONAL

Transcriptional Activation of HIF-1 by RORα and its Role in Hypoxia Signaling

(2008) Eun-Jin Kim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Favorable effects of a prolonged treatment with melatonin on the level of oxidative damage and neurodegeneration in senescence-accelerated mice

(2008) Beatriz Caballero et al.   JOURNAL OF PINEAL RESEARCH

Prevention of ischemia/reperfusion-induced cardiac apoptosis and injury by melatonin is independent of glutathione peroxdiase 1

(2008) Zhongyi Chen et al.   JOURNAL OF PINEAL RESEARCH