Lipid accumulation in human breast cancer cells injured by iron depletors

Oxygen availability and metabolic reprogramming in cancer

(2017) Hong Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MIF/CD74 axis is a target for novel therapies in colon carcinomatosis

(2017) Fabio Bozzi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nutrient acquisition strategies of mammalian cells

(2017) Wilhelm Palm et al.   NATURE

Sarcoplasmic reticulum–mitochondria communication in cardiovascular pathophysiology

(2017) Camila Lopez-Crisosto et al.   Nature Reviews Cardiology

In-line balanced detection stimulated Raman scattering microscopy

(2017) Francesco Crisafi et al.   Scientific Reports

Hydrogen peroxide-mediated induction of SOD1 gene transcription is independent from Nrf2 in a cellular model of neurodegeneration

(2016) Michela Dell'Orco et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Iron Homeostasis in Health and Disease

(2016) Raffaella Gozzelino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clinical iron deficiency disturbs normal human responses to hypoxia

(2016) Matthew C. Frise et al.   JOURNAL OF CLINICAL INVESTIGATION

Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1

(2016) L Zanotti et al.   LEUKEMIA

Developing a set of guidelines for your research field: a practical approach

(2016) Daniel J. Klionsky   MOLECULAR BIOLOGY OF THE CELL

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Paraptosis in the anti-cancer arsenal of natural products

(2016) Dongjoo Lee et al.   PHARMACOLOGY & THERAPEUTICS

Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER

(2016) J. Nixon-Abell et al.   SCIENCE

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

FADS2genotype regulates delta-6 desaturase activity and inflammation in human adipose tissue

(2015) Maija Vaittinen et al.   JOURNAL OF LIPID RESEARCH

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

(2015) Marie Lagouge et al.   PLoS Genetics

Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition

(2014) Yoav D. Shaul et al.   CELL

Evaluation of acridine orange, LysoTracker Red, and quinacrine as fluorescent probes for long-term tracking of acidic vesicles

(2014) Agnieszka Pierzyńska-Mach et al.   CYTOMETRY PART A

The Metastasis Suppressor, N-myc Downstream-regulated Gene 1 (NDRG1), Inhibits Stress-induced Autophagy in Cancer Cells

(2014) Sumit Sahni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deferoxamine inhibits TRAIL-mediated apoptosis via regulation of autophagy in human colon cancer cells

(2014) JI-HONG MOON et al.   ONCOLOGY REPORTS

Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

(2014) Daniel Ackerman et al.   TRENDS IN CELL BIOLOGY

Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells

(2013) K M Dixon et al.   BRITISH JOURNAL OF CANCER

Iron and Diabetes Risk

(2013) Judith A. Simcox et al.   Cell Metabolism

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress

(2013) R. M. Young et al.   GENES & DEVELOPMENT

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

(2013) Cosimo Commisso et al.   NATURE

The autophagosome: origins unknown, biogenesis complex

(2013) Christopher A. Lamb et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crucial Role of Perilipin-3 (TIP47) in Formation of Lipid Droplets and PGE2 Production in HL-60-Derived Neutrophils

(2013) Fuyuki Nose et al.   PLoS One

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

(2013) J. J. Kamphorst et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma

(2013) F. Guillaumond et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids

(2013) Nousheen Zaidi et al.   PROGRESS IN LIPID RESEARCH

Iron Deprivation in Cancer––Potential Therapeutic Implications

(2013) Jessica Heath et al.   Nutrients

The Iron-Regulated Metastasis Suppressor NDRG1 Targets NEDD4L, PTEN, and SMAD4 and Inhibits the PI3K and Ras Signaling Pathways

(2012) Zaklina Kovacevic et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Morphology in Metabolic Diseases

(2012) Chad A. Galloway et al.   ANTIOXIDANTS & REDOX SIGNALING

Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging

(2012) Kanchan Phadwal et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

(2012) Wen Liu et al.   EMBO Molecular Medicine

The Iron Chelators Dp44mT and DFO Inhibit TGF-β-induced Epithelial-Mesenchymal Transition via Up-Regulation of N-Myc Downstream-regulated Gene 1 (NDRG1)

(2012) Zhiqiang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-myc Downstream Regulated Gene 1 (NDRG1) Promotes Metastasis of Human Scirrhous Gastric Cancer Cells through Epithelial Mesenchymal Transition

(2012) Hiroki Ureshino et al.   PLoS One

Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells

(2012) Tarja A Juopperi et al.   Molecular Brain

The CK2 phosphorylation of catalytic domain of Cdc34 modulates its activity at the G1to S transition inSaccharomyces cerevisiae

(2011) Paola Coccetti et al.   CELL CYCLE

A chalcone-related small molecule that induces methuosis, a novel form of non-apoptotic cell death, in glioblastoma cells

(2011) Jean H Overmeyer et al.   Molecular Cancer

Chloroquine treatment of ARPE-19 cells leads to lysosome dilation and intracellular lipid accumulation: possible implications of lysosomal dysfunction in macular degeneration

(2011) Patrick M Chen et al.   Cell and Bioscience

Brain aging and Aβ1–42 neurotoxicity converge via deterioration in autophagy–lysosomal system: a conditional Drosophila model linking Alzheimer’s neurodegeneration with aging

(2010) Daijun Ling et al.   ACTA NEUROPATHOLOGICA

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line

(2010) Dario Caccia et al.   Molecular Cancer

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44

(2009) Shigeo Takaishi et al.   STEM CELLS

A phase I study of Triapine® in combination with doxorubicin in patients with advanced solid tumors

(2008) William R. Schelman et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Does iron have a role in breast cancer?

(2008) Xi Huang   LANCET ONCOLOGY

Proteomics study of medullary thyroid carcinomas expressing RET germ-line mutations: Identification of new signaling elements

(2008) L. Gorla et al.   MOLECULAR CARCINOGENESIS

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Hypoxia-inducible Factor-1α Stabilization in Nonhypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion

(2007) Elisabeth L. Pagé et al.   MOLECULAR BIOLOGY OF THE CELL