The Role of Low-Density Lipoprotein Receptor-Related Protein 1 in Lipid Metabolism, Glucose Homeostasis and Inflammation

Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in Müller Glial cells

(2018) Virginia Actis Dato et al.   BIOCHEMICAL JOURNAL

Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases CCR7 Expression in Plaque Macrophages

(2018) Paul A. Mueller et al.   CIRCULATION

Oxidized LDL phagocytosis during foam cell formation in atherosclerotic plaques relies on a PLD2-CD36 functional interdependence

(2018) Ramya Ganesan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Soluble LRP1 is an independent biomarker of epicardial fat volume in patients with type 1 diabetes mellitus

(2018) David de Gonzalo-Calvo et al.   Scientific Reports

Activated α2 -Macroglobulin Induces Mesenchymal Cellular Migration Of Raw264.7 Cells Through Low-Density Lipoprotein Receptor-Related Protein 1

(2017) Darío G. Ferrer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Electronegative Low-Density Lipoprotein L5 Induces Adipose Tissue Inflammation Associated With Metabolic Syndrome

(2017) Liang-Yin Ke et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes

(2017) Xiang Pan et al.   MOLECULAR BIOLOGY OF THE CELL

Apolipoprotein A5 regulates intracellular triglyceride metabolism in adipocytes

(2017) Xiao-Yan Zheng et al.   Molecular Medicine Reports

Update on GLUT4 Vesicle Traffic: A Cornerstone of Insulin Action

(2017) Javier R. Jaldin-Fincati et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis

(2017) Xunde Xian et al.   eLife

The LDL Receptor-Related Protein 1: At the Crossroads of Lipoprotein Metabolism and Insulin Signaling

(2017) Dianaly T. Au et al.   Journal of Diabetes Research

High Concentrations of Rosiglitazone Reduce mRNA and Protein Levels of LRP1 in HepG2 Cells

(2017) Alejandro N. Rondón-Ortiz et al.   Frontiers in Pharmacology

Loss of Macrophage Low-Density Lipoprotein Receptor–Related Protein 1 Confers Resistance to the Antiatherogenic Effects of Tumor Necrosis Factor-α InhibitionHighlights

(2016) Lin Zhu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The P2Y 2 receptor mediates uptake of matrix-retained and aggregated low density lipoprotein in primary vascular smooth muscle cells

(2016) Tixieanna Dissmore et al.   ATHEROSCLEROSIS

Atherosclerosis

(2016) Frank Schaftenaar et al.   CURRENT OPINION IN LIPIDOLOGY

The central role of arterial retention of cholesterol-rich apolipoprotein-B-containing lipoproteins in the pathogenesis of atherosclerosis

(2016) Jan Borén et al.   CURRENT OPINION IN LIPIDOLOGY

Low density lipoprotein receptor-related protein 1 mediated endocytosis of β1-integrin influences cell adhesion and cell migration

(2016) Verena K. Rabiej et al.   EXPERIMENTAL CELL RESEARCH

TRPM7 channel regulates ox-LDL-induced proliferation and migration of vascular smooth muscle cells via MEK-ERK pathways

(2016) Jinghan Lin et al.   FEBS LETTERS

The insulin-like growth factor I receptor regulates glucose transport by astrocytes

(2016) Edwin Hernandez-Garzón et al.   GLIA

Circulating levels of soluble low-density lipoprotein receptor-related protein 1 (sLRP1) as novel biomarker of epicardial adipose tissue

(2016) D. de Gonzalo-Calvo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation

(2016) Zeina El Asmar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LDL receptor-related protein-1 regulates NFκB and microRNA-155 in macrophages to control the inflammatory response

(2016) Elisabetta Mantuano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis

(2016) Yinyuan Ding et al.   EBioMedicine

Circulating soluble low-density lipoprotein receptor-related protein 1 (sLRP1) concentration is associated with hypercholesterolemia: A new potential biomarker for atherosclerosis

(2015) D. de Gonzalo-Calvo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

K Domain CR9 of Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1) Is Critical for Aggregated LDL-induced Foam Cell Formation from Human Vascular Smooth Muscle Cells

(2015) Paula Costales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal LRP1 Regulates Glucose Metabolism and Insulin Signaling in the Brain

(2015) C.-C. Liu et al.   JOURNAL OF NEUROSCIENCE

LDL biochemical modifications: a link between atherosclerosis and aging

(2015) Matilde Alique et al.   Food & Nutrition Research

LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages

(2015) Anna P. Lillis et al.   PLoS One

Perivascular Adipose Tissue in Vascular Function and Disease

(2014) Nicholas K. Brown et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proinflammatory Phenotype of Perivascular Adipocytes

(2014) Abdullah Omar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Standardized flow cytometry assay for identification of human monocytic heterogeneity and LRP1 expression in monocyte subpopulations: Decreased expression of this receptor in nonclassical monocytes

(2014) Darío G. Ferrer et al.   CYTOMETRY PART A

GLUT2, glucose sensing and glucose homeostasis

(2014) Bernard Thorens   DIABETOLOGIA

Cardiomyocyte intracellular cholesteryl ester accumulation promotes tropoelastin physical alteration and degradation

(2014) Valerie Samouillan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo

(2014) Manikandan Subramanian et al.   JOURNAL OF CLINICAL INVESTIGATION

LDL Receptor–Related Protein-1

(2013) Steven L. Gonias et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of MSR-1 and CD36 in macrophages by LOX-1 mediated through PPAR-γ

(2013) Yao Dai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activated α2-macroglobulin induces Müller glial cell migration by regulating MT1-MMP activity through LRP1

(2013) Pablo F. Barcelona et al.   FASEB JOURNAL

Top Single Nucleotide Polymorphisms Affecting Carbohydrate Metabolism in Metabolic Syndrome: From the LIPGENE Study

(2013) Javier Delgado-Lista et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The SLC2 (GLUT) family of membrane transporters

(2013) Mike Mueckler et al.   MOLECULAR ASPECTS OF MEDICINE

Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin

(2013) Guanrong Huang et al.   MOLECULAR BIOLOGY OF THE CELL

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

The Cardiovascular Safety of Diabetes Drugs — Insights from the Rosiglitazone Experience

(2013) William R. Hiatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of Glucose Transporter Translocation in Health and Diabetes

(2012) Jonathan S. Bogan   Annual Review of Biochemistry

Lipid Loading of Human Vascular Smooth Muscle Cells Induces Changes in Tropoelastin Protein Levels and Physical Structure

(2012) Valerie Samouillan et al.   BIOPHYSICAL JOURNAL

Low Density Lipoprotein Receptor-Related Protein 1 Dependent Endosomal Trapping and Recycling of Apolipoprotein E

(2012) Alexander Laatsch et al.   PLoS One

Apolipoprotein E Induces Antiinflammatory Phenotype in Macrophages

(2011) Daniel Baitsch et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of the Urokinase Receptor (uPAR) by LDL Receptor-related Protein-1 (LRP1)

(2011) Steven L. Gonias et al.   CURRENT PHARMACEUTICAL DESIGN

The role of elastin peptides in modulating the immune response in aging and age-related diseases

(2011) T. Fulop et al.   PATHOLOGIE BIOLOGIE

Macrophage LRP1 Suppresses Neo-Intima Formation during Vascular Remodeling by Modulating the TGF-β Signaling Pathway

(2011) Selen Catania Muratoglu et al.   PLoS One

Macrophage LRP-1 Controls Plaque Cellularity by Regulating Efferocytosis and Akt Activation

(2010) Patricia G. Yancey et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Signaling through LRP1: Protection from atherosclerosis and beyond

(2010) Philippe Boucher et al.   BIOCHEMICAL PHARMACOLOGY

Metabolic Syndrome: From the Genetics to the Pathophysiology

(2010) Silvia Sookoian et al.   CURRENT HYPERTENSION REPORTS

Immunohistochemical localization of low density lipoprotein receptor-related protein 1 and α2-Macroglobulin in retinal and choroidal tissue of proliferative retinopathies

(2010) P.F. Barcelona et al.   EXPERIMENTAL EYE RESEARCH

Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages

(2010) Matvey Gorovoy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

(2009) Mark P. Jedrychowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

(2008) Alexander Laatsch et al.   ATHEROSCLEROSIS