High Concentrations of Rosiglitazone Reduce mRNA and Protein Levels of LRP1 in HepG2 Cells

Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ

(2017) Hua Mao et al.   Nature Communications

Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

(2017) Martine C. Morrison et al.   Scientific Reports

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Clinical Pharmacokinetics and Pharmacodynamics of Antihyperglycemic Medications in Children and Adolescents with Type 2 Diabetes Mellitus

(2016) Fatemeh Akhlaghi et al.   CLINICAL PHARMACOKINETICS

Neuronal LRP1 Regulates Glucose Metabolism and Insulin Signaling in the Brain

(2015) C.-C. Liu et al.   JOURNAL OF NEUROSCIENCE

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

(2015) Zhen Zhao et al.   NATURE NEUROSCIENCE

Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer’s disease: the role, regulation and restoration of LRP1

(2015) Anita Ramanathan et al.   Frontiers in Aging Neuroscience

The Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor Environment

(2015) Bart Van Gool et al.   Frontiers in Pharmacology

Low-Density Lipoprotein Receptor–Related Protein-1

(2014) Dudley K. Strickland et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae

(2014) Yoshimitsu Kanai et al.   JOURNAL OF CELL BIOLOGY

Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Regulates the Stability and Function of GluA1 α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic Acid (AMPA) Receptor in Neurons

(2014) Ming Gan et al.   PLoS One

The role of protein clearance mechanisms in organismal ageing and age-related diseases

(2014) David Vilchez et al.   Nature Communications

Neuronal Clearance of Amyloid-  by Endocytic Receptor LRP1

(2013) T. Kanekiyo et al.   JOURNAL OF NEUROSCIENCE

The hypolipidemic effect of cilostazol can be mediated by regulation of hepatic low-density lipoprotein receptor-related protein 1 (LRP1) expression

(2013) Hyung Jun Kim et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

The Cardiovascular Safety of Diabetes Drugs — Insights from the Rosiglitazone Experience

(2013) William R. Hiatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma

(2013) D Vara et al.   Cell Death & Disease

Aggregated Low-Density Lipoprotein Induces LRP1 Stabilization Through E3 Ubiquitin Ligase CHFR Downregulation in Human Vascular Smooth Muscle Cells

(2012) Roi Cal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Low Density Lipoprotein Receptor Related Protein 1 and Abdominal Aortic Aneurysms

(2012) J.B. Wild et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

Upregulation of hepatic LRP1 by rosiglitazone: a possible novel mechanism of the beneficial effect of thiazolidinediones on atherogenic dyslipidemia

(2012) Jae Hoon Moon et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

LRP-1-CD44, a New Cell Surface Complex Regulating Tumor Cell Adhesion

(2012) G. Perrot et al.   MOLECULAR AND CELLULAR BIOLOGY

Low-density lipoprotein receptor-related protein 1: A physiological Aβ homeostatic mechanism with multiple therapeutic opportunities

(2012) Abhay P. Sagare et al.   PHARMACOLOGY & THERAPEUTICS

Low Density Lipoprotein Receptor-Related Protein 1 Dependent Endosomal Trapping and Recycling of Apolipoprotein E

(2012) Alexander Laatsch et al.   PLoS One

Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications

(2012) Aleksi Tornio et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1

(2011) Matthew J. Bown et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Rosiglitazone induces autophagy in H295R and cell cycle deregulation in SW13 adrenocortical cancer cells

(2011) Lidia Cerquetti et al.   EXPERIMENTAL CELL RESEARCH

The effect of rosiglitazone on LRP1 expression and amyloid β uptake in human brain microvascular endothelial cells: a possible role of a low-dose thiazolidinedione for dementia treatment

(2011) Jae Hoon Moon et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

From the liver to the blood-brain barrier: An interconnected system regulating brain amyloid-β levels

(2011) Abhay P. Sagare et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Mediates Neuronal Aβ42 Uptake and Lysosomal Trafficking

(2010) Rodrigo A. Fuentealba et al.   PLoS One

In search of an “autophagomometer”

(2009) David C. Rubinsztein et al.   Autophagy

PPARγ activation induces autophagy in breast cancer cells

(2009) Jie Zhou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

(2009) Mark P. Jedrychowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

PPAR-γ AF-2 Domain Functions as a Component of a Ubiquitin-dependent Degradation Signal

(2009) Gail E. Kilroy et al.   Obesity

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

(2008) Alexander Laatsch et al.   ATHEROSCLEROSIS

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS