The LDL Receptor-Related Protein 1: At the Crossroads of Lipoprotein Metabolism and Insulin Signaling

Modeling Sporadic Alzheimer's Disease: The Insulin Resistant Brain State Generates Multiple Long-Term Morphobiological Abnormalities Including Hyperphosphorylated Tau Protein and Amyloid-β

(2017) Melita Salkovic-Petrisic et al.   JOURNAL OF ALZHEIMERS DISEASE

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

(2016) Philip L.S.M. Gordts et al.   JOURNAL OF CLINICAL INVESTIGATION

Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis

(2016) Yinyuan Ding et al.   EBioMedicine

Neuronal LRP1 Regulates Glucose Metabolism and Insulin Signaling in the Brain

(2015) C.-C. Liu et al.   JOURNAL OF NEUROSCIENCE

Association of rs1466535 LRP1 but not rs3019885 SLC30A8 and rs6674171 TDRD10 gene polymorphisms with abdominal aortic aneurysm in Italian patients

(2015) Silvia Galora et al.   JOURNAL OF VASCULAR SURGERY

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

(2015) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Low-Density Lipoprotein Receptor–Related Protein-1

(2014) Dudley K. Strickland et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development

(2014) C. Nakajima et al.   DEVELOPMENT

GLUT2, glucose sensing and glucose homeostasis

(2014) Bernard Thorens   DIABETOLOGIA

Insulin-regulated Glut4 Translocation

(2014) Paul Duffield Brewer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Delivery of circulating lipoproteins to specific neurons in the Drosophila brain regulates systemic insulin signaling

(2014) Marko Brankatschk et al.   eLife

Insulin in the Brain: Its Pathophysiological Implications for States Related with Central Insulin Resistance, Type 2 Diabetes and Alzheimer’s Disease

(2014) Enrique Blázquez et al.   Frontiers in Endocrinology

LDL Receptor–Related Protein-1

(2013) Steven L. Gonias et al.   AMERICAN JOURNAL OF PATHOLOGY

Genome-Wide-Associated Variants in Migraine Susceptibility: A Replication Study From North India

(2013) Jayashri Ghosh et al.   HEADACHE

Top Single Nucleotide Polymorphisms Affecting Carbohydrate Metabolism in Metabolic Syndrome: From the LIPGENE Study

(2013) Javier Delgado-Lista et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Low density lipoprotein receptor–related protein 1 is upregulated in epicardial fat from type 2 diabetes mellitus patients and correlates with glucose and triglyceride plasma levels

(2012) L. Nasarre et al.   ACTA DIABETOLOGICA

Affinity between TBC1D4 (AS160) phosphotyrosine-binding domain and insulin-regulated aminopeptidase cytoplasmic domain measured by isothermal titration calorimetry

(2012) Sang-Youn Park et al.   BMB Reports

Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1

(2011) Matthew J. Bown et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Insulin-producing cells in the brain of adult Drosophila are regulated by the serotonin 5-HT1A receptor

(2011) Jiangnan Luo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Myocardial, Perivascular, and Epicardial Fat

(2011) P. Iozzo   DIABETES CARE

Persistent glucose transporter expression on pancreatic beta cells from longstanding type 1 diabetic individuals

(2011) Ken T. Coppieters et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: Implications for understanding genetic association signals at this locus

(2011) Laura J. McCulloch et al.   MOLECULAR GENETICS AND METABOLISM

Genome-wide association study reveals three susceptibility loci for common migraine in the general population

(2011) Daniel I Chasman et al.   NATURE GENETICS

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Glucose transporters in the 21st Century

(2009) Bernard Thorens et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Harmonizing the Metabolic Syndrome

(2009) K.G.M.M. Alberti et al.   CIRCULATION

Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

(2009) Mark P. Jedrychowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic Analysis of Src Family Kinases Signaling Complexes in Golgi/Endosomal Fractions Using a Site-Selective Anti-Phosphotyrosine Antibody: Identification of LRP1-Insulin Receptor Complexes

(2009) Nicolas Bilodeau et al.   JOURNAL OF PROTEOME RESEARCH

Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1

(2009) Miklos Guttman et al.   PROTEOMICS

Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance

(2008) Alexander Laatsch et al.   ATHEROSCLEROSIS

SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells

(2008) Robert D. Bell et al.   NATURE CELL BIOLOGY

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS