Regulation of Glucose Transporter Translocation in Health and Diabetes

Vimentin binds IRAP and is involved in GLUT4 vesicle trafficking

(2011) Yohko Hirata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endocytosis, Recycling, and Regulated Exocytosis of Glucose Transporter 4

(2011) Kevin Foley et al.   BIOCHEMISTRY

Functional Transformation of Gastric Parietal Cells and Intracellular Trafficking of Ion Channels/Transporters in the Apical Canalicular Membrane Associated with Acid Secretion

(2011) Fumiyo Aoyama et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Leucyl/Cystinyl Aminopeptidase Gene Variants in Septic Shock

(2011) Taka-aki Nakada et al.   CHEST

Clustering of GLUT4, TUG, and RUVBL2 protein levels correlate with myosin heavy chain isoform pattern in skeletal muscles, but AS160 and TBC1D1 levels do not

(2011) Carlos M. Castorena et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Ubiquitin Regulatory X (UBX) Domain-containing Protein TUG Regulates the p97 ATPase and Resides at the Endoplasmic Reticulum-Golgi Intermediate Compartment

(2011) Charisse M. Orme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetic Evidence That Glut4 Follows Different Endocytic Pathways than the Receptors for Transferrin and α2-Macroglobulin

(2011) Estifanos N. Habtemichael et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-stimulated GLUT4 Protein Translocation in Adipocytes Requires the Rab10 Guanine Nucleotide Exchange Factor Dennd4C

(2011) Hiroyuki Sano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of AS160 Akt Substrate Causes Glut4 Protein to Accumulate in Compartments That Are Primed for Fusion in Basal Adipocytes

(2011) Paul Duffield Brewer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AS160 Phosphotyrosine-binding Domain Constructs Inhibit Insulin-stimulated GLUT4 Vesicle Fusion with the Plasma Membrane

(2011) Françoise Koumanov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis

(2011) Jenna L. Jewell et al.   JOURNAL OF CELL BIOLOGY

Dual-mode of insulin action controls GLUT4 vesicle exocytosis

(2011) Yingke Xu et al.   JOURNAL OF CELL BIOLOGY

Exocyst function regulated by effector phosphorylation

(2011) Xiao-Wei Chen et al.   NATURE CELL BIOLOGY

The Sugar Is sIRVed: Sorting Glut4 and Its Fellow Travelers

(2011) Konstantin V. Kandror et al.   TRAFFIC

The capture of phosphoproteins by 14-3-3 proteins mediates actions of insulin

(2011) Shuai Chen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

PKD Regulates Membrane Fission to Generate TGN to Cell Surface Transport Carriers

(2011) V. Malhotra et al.   Cold Spring Harbor Perspectives in Biology

The Golgin Coiled-Coil Proteins of the Golgi Apparatus

(2011) S. Munro   Cold Spring Harbor Perspectives in Biology

Stimulation of GLUT4 (glucose transporter isoform 4) storage vesicle formation by sphingolipid depletion

(2010) Zhi-Jie Cheng et al.   BIOCHEMICAL JOURNAL

Identification of Type 2 Diabetes-associated combination of SNPs using Support Vector Machine

(2010) Hyo-Jeong Ban et al.   BMC GENETICS

Biogenesis and regulation of insulin-responsive vesicles containing GLUT4

(2010) Jonathan S Bogan et al.   CURRENT OPINION IN CELL BIOLOGY

Sortilins: new players in lipoprotein metabolism

(2010) Thomas E Willnow et al.   CURRENT OPINION IN LIPIDOLOGY

Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption

(2010) J. R. Ussher et al.   DIABETES

Wnt signaling regulates mitochondrial physiology and insulin sensitivity

(2010) J. C. Yoon et al.   GENES & DEVELOPMENT

Regulation of Integrin β1 Recycling to Lipid Rafts by Rab1a to Promote Cell Migration

(2010) Chenran Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myo1c Regulates Glucose Uptake in Mouse Skeletal Muscle

(2010) Taro Toyoda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitate-induced Down-regulation of Sortilin and Impaired GLUT4 Trafficking in C2C12 Myotubes

(2010) Yo Tsuchiya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Placental Leucine Aminopeptidase- and Aminopeptidase A- Deficient Mice Offer Insight concerning the Mechanisms Underlying Preterm Labor and Preeclampsia

(2010) Shigehiko Mizutani et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step

(2010) Christopher Esk et al.   JOURNAL OF CELL BIOLOGY

Reassessment of Models of Facilitated Transport and Cotransport

(2010) Richard J. Naftalin   JOURNAL OF MEMBRANE BIOLOGY

Exercise-induced TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle

(2010) Christian Frøsig et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lipid-induced insulin resistance: unravelling the mechanism

(2010) Varman T Samuel et al.   LANCET

Syntaxin 6 and CAL Mediate the Degradation of the Cystic Fibrosis Transmembrane Conductance Regulator

(2010) Jie Cheng et al.   MOLECULAR BIOLOGY OF THE CELL

AS160 Associates with the Na+,K+-ATPase and Mediates the Adenosine Monophosphate-stimulated Protein Kinase-dependent Regulation of Sodium Pump Surface Expression

(2010) Daiane S. Alves et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of Three Distinct Functional Sites of Insulin-mediated GLUT4 Trafficking in Adipocytes Using Quantitative Single Molecule Imaging

(2010) Hideaki Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Insulin-regulated Aminopeptidase Is a Key Regulator of GLUT4 Trafficking by Controlling the Sorting of GLUT4 from Endosomes to Specialized Insulin-regulated Vesicles

(2010) Ingrid Jordens et al.   MOLECULAR BIOLOGY OF THE CELL

A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action

(2010) Xiao-Wei Chen et al.   MOLECULAR BIOLOGY OF THE CELL

Insulin-Regulated Trafficking of GLUT4 Requires Ubiquitination

(2010) Christopher A. Lamb et al.   TRAFFIC

Glucose transporters in the 21st Century

(2009) Bernard Thorens et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

GAPDH binds GLUT4 reciprocally to hexokinase-II and regulates glucose transport activity

(2009) Hilal Zaid et al.   BIOCHEMICAL JOURNAL

A Negative Regulatory Pathway of GLUT4 Trafficking in Adipocyte: New Function of RIP140 in the Cytoplasm via AS160

(2009) Ping-Chih Ho et al.   Cell Metabolism

RUVBL2, a novel AS160-binding protein, regulates insulin-stimulated GLUT4 translocation

(2009) Xiangyang Xie et al.   CELL RESEARCH

RAPGEF1 gene variants associated with type 2 diabetes in the Korean population

(2009) Kyung-Won Hong et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Emerging new roles of the pre-Golgi intermediate compartment in biosynthetic-secretory trafficking

(2009) Jaakko Saraste et al.   FEBS LETTERS

Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

(2009) Mark P. Jedrychowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cerebellar Neurons Possess a Vesicular Compartment Structurally and Functionally Similar to Glut4-Storage Vesicles from Peripheral Insulin-Sensitive Tissues

(2009) K. Bakirtzi et al.   JOURNAL OF NEUROSCIENCE

Gene knockout of insulin-regulated aminopeptidase: Loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory

(2009) Anthony L. Albiston et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia

(2009) S. Dash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Role for the CHC22 Clathrin Heavy-Chain Isoform in Human Glucose Metabolism

(2009) S. Vassilopoulos et al.   SCIENCE

IRAP Identifies an Endosomal Compartment Required for MHC Class I Cross-Presentation

(2009) L. Saveanu et al.   SCIENCE

Four grams of glucose

(2008) David H. Wasserman   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The C-terminus of GLUT4 targets the transporter to the perinuclear compartment but not to the insulin-responsive vesicles

(2008) Lin V. Li et al.   BIOCHEMICAL JOURNAL

UBXD7 Binds Multiple Ubiquitin Ligases and Implicates p97 in HIF1α Turnover

(2008) Gabriela Alexandru et al.   CELL

CaMKII-Mediated Phosphorylation of the Myosin Motor Myo1c Is Required for Insulin-Stimulated GLUT4 Translocation in Adipocytes

(2008) Ming Fai Yip et al.   Cell Metabolism

IRS1-Independent Defects Define Major Nodes of Insulin Resistance

(2008) Kyle L. Hoehn et al.   Cell Metabolism

UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

(2008) C. Schuberth et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ca2+ and insulin-mediated glucose uptake

(2008) J LANNER et al.   CURRENT OPINION IN PHARMACOLOGY

Comprehensive Association Study of Type 2 Diabetes and Related Quantitative Traits With 222 Candidate Genes

(2008) K. J. Gaulton et al.   DIABETES

A Transgenic Mouse Model to Study Glucose Transporter 4mycRegulation in Skeletal Muscle

(2008) Jonathan D. Schertzer et al.   ENDOCRINOLOGY

Selective regulation of the perinuclear distribution of glucose transporter 4 (GLUT4) by insulin signals in muscle cells

(2008) Chandrasagar B. Dugani et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population

(2008) D. Meyre et al.   HUMAN MOLECULAR GENETICS

Self-assembly of Glut4 Storage Vesicles during Differentiation of 3T3-L1 Adipocytes

(2008) Jun Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRP1 Controls Intracellular Cholesterol Storage and Fatty Acid Synthesis through Modulation of Wnt Signaling

(2008) Jérome Terrand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of GLUT4 Translocation by Tbc1d1, a Rab GTPase-activating Protein Abundant in Skeletal Muscle, Is Partially Relieved by AMP-activated Protein Kinase Activation

(2008) Jose A. Chavez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Splicing in Class V Myosins Determines Association with Rab10

(2008) Joseph T. Roland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocytosis of Apolipoprotein A-V by Members of the Low Density Lipoprotein Receptor and the Vps10p Domain Receptor Families

(2008) Stefan K. Nilsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

(2008) Eric B. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recycling of IRAP from the plasma membrane back to the insulin-responsive compartment requires the Q-SNARE syntaxin 6 but not the GGA clathrin adaptors

(2008) R. T. Watson et al.   JOURNAL OF CELL SCIENCE

Activation of atypical protein kinase Cζ toward TC10 is regulated by high-fat diet and aerobic exercise in skeletal muscle

(2008) Misato Saito et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Exercise training increases components of the c-Cbl–associated protein/c-Cbl signaling cascade in muscle of obese Zucker rats

(2008) Jeffrey R. Bernard et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Insulin Stimulates Phosphatidylinositol 3-Phosphate Production via the Activation of Rab5

(2008) Irfan J. Lodhi et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular Mechanisms Controlling GLUT4 Intracellular Retention

(2008) Vincent Blot et al.   MOLECULAR BIOLOGY OF THE CELL

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

(2008) Alexandra Chadt et al.   NATURE GENETICS

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

(2008) Cristen J Willer et al.   NATURE GENETICS

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Skeletal muscle munc18c and syntaxin 4 in human obesity

(2008) Bryan C Bergman et al.   Nutrition & Metabolism

High-fat Diet Alters PP2A, TC10, and CIP4 Expression in Visceral Adipose Tissue of Rats

(2008) Hye-Seung Jun et al.   Obesity

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS

The effect of exercise and insulin on AS160 phosphorylation and 14-3-3 binding capacity in human skeletal muscle

(2007) Kirsten F. Howlett et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The GLUT4 Code

(2007) Mark Larance et al.   MOLECULAR ENDOCRINOLOGY