From glycophenotyping by (plant) lectin histochemistry to defining functionality of glycans by pairing with endogenous lectins

Three-step monitoring of glycan and galectin profiles in the anterior segment of the adult chicken eye

(2018) Joachim C. Manning et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Adhesion/growth-regulatory galectins tested in combination: evidence for formation of hybrids as heterodimers

(2018) Michelle C. Miller et al.   BIOCHEMICAL JOURNAL

Exploring functional pairing between surface glycoconjugates and human galectins using programmable glycodendrimersomes

(2018) Qi Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Members of the Galectin Network with Deviations from the Canonical Sequence Signature. 1. Galectin-Related Inter-Fiber Protein (GRIFIN)

(2018) Gabriel García Caballero et al.   TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY

Network analysis of adhesion/growth-regulatory galectins and their binding sites in adult chicken retina and choroid

(2017) Joachim C. Manning et al.   JOURNAL OF ANATOMY

Studying the Structural Significance of Galectin Design by Playing a Modular Puzzle: Homodimer Generation from Human Tandem-Repeat-Type (Heterodimeric) Galectin-8 by Domain Shuffling

(2017) Anna-Kristin Ludwig et al.   MOLECULES

F-Type Lectins: A Highly Diversified Family of Fucose-Binding Proteins with a Unique Sequence Motif and Structural Fold, Involved in Self/Non-Self-Recognition

(2017) Gerardo R. Vasta et al.   Frontiers in Immunology

Neurons define non-myelinated axon segments by the regulation of galectin-4-containing axon membrane domains

(2017) Natalia Díez-Revuelta et al.   Scientific Reports

Galectin-related protein: An integral member of the network of chicken galectins

(2016) Herbert Kaltner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Galectin-related protein: An integral member of the network of chicken galectins 1. From strong sequence conservation of the gene confined to vertebrates to biochemical characteristics of the chicken protein and its crystal structure

(2016) Gabriel García Caballero et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Chicken GRIFIN: A homodimeric member of the galectin network with canonical properties and a unique expression profile

(2016) Gabriel García Caballero et al.   BIOCHIMIE

Sweet complementarity: the functional pairing of glycans with lectins

(2016) H.-J. Gabius et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Multi-level regulation of cellular glycosylation: from genes to transcript to enzyme to structure

(2016) Sriram Neelamegham et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Nanoscale materials for probing the biological functions of the glycocalyx

(2016) Mia L Huang et al.   GLYCOBIOLOGY

Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design

(2016) René Roy et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Sialylation of N-glycans: mechanism, cellular compartmentalization and function

(2016) Gaurang P. Bhide et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The sugar code in neuronal physiology

(2016) Alonso M. Higuero et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Quality control of glycoprotein folding and ERAD: the role of N-glycan handling, EDEM1 and OS-9

(2016) Jürgen Roth et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Galectins: their network and roles in immunity/tumor growth control

(2016) Herbert Kaltner et al.   HISTOCHEMISTRY AND CELL BIOLOGY

An introduction to the sugar code

(2016) Hans-Joachim Gabius et al.   HISTOCHEMISTRY AND CELL BIOLOGY

C-type lectins: their network and roles in pathogen recognition and immunity

(2016) Sabine Mayer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Lipid glycosylation: a primer for histochemists and cell biologists

(2016) Jürgen Kopitz   HISTOCHEMISTRY AND CELL BIOLOGY

Lectins: a primer for histochemists and cell biologists

(2016) Joachim C. Manning et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Eukaryotic protein glycosylation: a primer for histochemists and cell biologists

(2016) Anthony Corfield   HISTOCHEMISTRY AND CELL BIOLOGY

Multivalent Carbohydrate-Lectin Interactions: How Synthetic Chemistry Enables Insights into Nanometric Recognition

(2016) René Roy et al.   MOLECULES

Playing Modular Puzzle with Adhesion/Growth-Regulatory Galectins: Design and Testing of a Hybrid to Unravel Structure-Activity Relationships

(2016) Anna-Kristin Ludwig et al.   PROTEIN AND PEPTIDE LETTERS

Why Do Membranes of Some Unhealthy Cells Adopt a Cubic Architecture?

(2016) Qi Xiao et al.   ACS Central Science

Galectin-3 Induces a Pro-degradative/inflammatory Gene Signature in Human Chondrocytes, Teaming Up with Galectin-1 in Osteoarthritis Pathogenesis

(2016) Daniela Weinmann et al.   Scientific Reports

Network Monitoring of Adhesion/Growth-Regulatory Galectins: Localization of the Five Canonical Chicken Proteins in Embryonic and Maturing Bone and Cartilage and Their Introduction as Histochemical Tools

(2015) Herbert Kaltner et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Dissecting Molecular Aspects of Cell Interactions Using Glycodendrimersomes with Programmable Glycan Presentation and Engineered Human Lectins

(2015) Shaodong Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mucins: A biologically relevant glycan barrier in mucosal protection

(2015) Anthony P. Corfield   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code

(2015) Dolores Solís et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity

(2015) Michael D. Swanson et al.   CELL

GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model

(2015) Piotr Hadaczek et al.   EXPERIMENTAL NEUROLOGY

Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context

(2015) Sabine André et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Lectin Engineering, a Molecular Evolutionary Approach to Expanding the Lectin Utilities

(2015) Dan Hu et al.   MOLECULES

Recognition of microbial glycans by human intelectin-1

(2015) Darryl A Wesener et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural significance of galectin design: impairment of homodimer stability by linker insertion and partial reversion by ligand presence

(2015) Sabine Vértesy et al.   PROTEIN ENGINEERING DESIGN & SELECTION

The magic of the sugar code

(2015) Hans-Joachim Gabius   TRENDS IN BIOCHEMICAL SCIENCES

The glycobiology of the CD system: a dictionary for translating marker designations into glycan/lectin structure and function

(2015) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

The multi-tasked life of GM1 ganglioside, a true factotum of nature

(2015) Robert W. Ledeen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Glycan variation and evolution in the eukaryotes

(2015) Anthony P. Corfield et al.   TRENDS IN BIOCHEMICAL SCIENCES

Gangliosides: glycosphingolipids essential for normal neural development and function

(2015) Cara-Lynne Schengrund   TRENDS IN BIOCHEMICAL SCIENCES

Congenital disorders of glycosylation: a concise chart of glycocalyx dysfunction

(2015) Thierry Hennet et al.   TRENDS IN BIOCHEMICAL SCIENCES

Recognition of microbial glycans by human intelectin-1

(2015) Darryl A Wesener et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human chimera-type galectin-3: Defining the critical tail length for high-affinity glycoprotein/cell surface binding and functional competition with galectin-1 in neuroblastoma cell growth regulation

(2014) Jürgen Kopitz et al.   BIOCHIMIE

The Challenge and Promise of Glycomics

(2014) Richard D. Cummings et al.   CHEMISTRY & BIOLOGY

Human osteoarthritic knee cartilage: fingerprinting of adhesion/growth-regulatory galectins in vitro and in situ indicates differential upregulation in severe degeneration

(2014) Stefan Toegel et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Restoration of Compact Golgi Morphology in Advanced Prostate Cancer Enhances Susceptibility to Galectin-1-Induced Apoptosis by Modifying Mucin O-Glycan Synthesis

(2014) A. Petrosyan et al.   MOLECULAR CANCER RESEARCH

Deciphering post-translational modification codes

(2013) Adam P. Lothrop et al.   FEBS LETTERS

Modular Synthesis of Amphiphilic Janus Glycodendrimers and Their Self-Assembly into Glycodendrimersomes and Other Complex Architectures with Bioactivity to Biomedically Relevant Lectins

(2013) Virgil Percec et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1

(2012) Robert W. Ledeen et al.   Annals of the New York Academy of Sciences

Tumour suppressor p16INK4a- anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model

(2012) Maho Amano et al.   FEBS Journal

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Allosteric post-translational modification codes

(2012) Ruth Nussinov et al.   TRENDS IN BIOCHEMICAL SCIENCES

Galactofuranose in eukaryotes: aspects of biosynthesis and functional impact

(2011) B. Tefsen et al.   GLYCOBIOLOGY

Lectins for histochemical demonstration of glycans

(2011) Jürgen Roth   HISTOCHEMISTRY AND CELL BIOLOGY

From lectin structure to functional glycomics: principles of the sugar code

(2011) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers—are they the cause or the consequence of the disease?

(2010) Morten Asser Karsdal et al.   CLINICAL BIOCHEMISTRY

Tumor suppressor p16INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model

(2010) Hugo Sanchez-Ruderisch et al.   FEBS Journal

From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans

(2009) Sabine André et al.   BIOLOGICAL CHEMISTRY

Chemistry and Biology of Galactofuranose-Containing Polysaccharides

(2009) Michele R. Richards et al.   CHEMBIOCHEM

Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): A gene-dependent effect on the cell surface glycan profile

(2009) G. Patsos et al.   GLYCOBIOLOGY

Cross-Linking of GM1 Ganglioside by Galectin-1 Mediates Regulatory T Cell Activity Involving TRPC5 Channel Activation: Possible Role in Suppressing Experimental Autoimmune Encephalomyelitis

(2009) J. Wang et al.   JOURNAL OF IMMUNOLOGY

The repertoire of glycan determinants in the human glycome

(2009) Richard D. Cummings   Molecular BioSystems

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

(2009) R. Goetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of N-Linked Glycosylation Disrupts Receptor Tyrosine Kinase Signaling in Tumor Cells

(2008) J. N. Contessa et al.   CANCER RESEARCH

Recent knowledge and innovations related to hexofuranosides: structure, synthesis and applications

(2008) Pauline Peltier et al.   CARBOHYDRATE RESEARCH

Regulation of Glycan Structures in Animal Tissues

(2008) Alison V. Nairn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY