Quality control of glycoprotein folding and ERAD: the role of N-glycan handling, EDEM1 and OS-9

Sialylation of N-glycans: mechanism, cellular compartmentalization and function

(2016) Gaurang P. Bhide et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Eukaryotic protein glycosylation: a primer for histochemists and cell biologists

(2016) Anthony Corfield   HISTOCHEMISTRY AND CELL BIOLOGY

Posttranscriptional Regulation of Glycoprotein Quality Control in the Endoplasmic Reticulum Is Controlled by the E2 Ub-Conjugating Enzyme UBC6e

(2016) Masatoshi Hagiwara et al.   MOLECULAR CELL

In vivo aspects of protein folding and quality control

(2016) D. Balchin et al.   SCIENCE

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

Cotranslational and posttranslocational N-glycosylation of proteins in the endoplasmic reticulum

(2015) Shiteshu Shrimal et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Effects of N-glycan precursor length diversity on quality control of protein folding and on protein glycosylation

(2015) John Samuelson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase

(2014) Sujin Park et al.   HISTOCHEMISTRY AND CELL BIOLOGY

EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step

(2014) Satoshi Ninagawa et al.   JOURNAL OF CELL BIOLOGY

Endoplasmic reticulum lectin XTP3-B inhibits endoplasmic reticulum-associated degradation of a misfolded α1-antitrypsin variant

(2013) Tsutomu Fujimori et al.   FEBS Journal

SEL1L Is Required for Endoplasmic Reticulum-associated Degradation of Misfolded Luminal Proteins but not Transmembrane Proteins in Chicken DT40 Cell Line

(2011) Satoshi Ninagawa et al.   CELL STRUCTURE AND FUNCTION

SEL1L Protein Critically Determines the Stability of the HRD1-SEL1L Endoplasmic Reticulum-associated Degradation (ERAD) Complex to Optimize the Degradation Kinetics of ERAD Substrates

(2011) Yasutaka Iida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Complex of Pdi1p and the Mannosidase Htm1p Initiates Clearance of Unfolded Glycoproteins from the Endoplasmic Reticulum

(2011) Robert Gauss et al.   MOLECULAR CELL

Structural Basis of an ERAD Pathway Mediated by the ER-Resident Protein Disulfide Reductase ERdj5

(2011) Masatoshi Hagiwara et al.   MOLECULAR CELL

Protein N-glycosylation, protein folding, and protein quality control

(2011) Jürgen Roth et al.   MOLECULES AND CELLS

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

The role of MRH domain-containing lectins in ERAD

(2010) N. Hosokawa et al.   GLYCOBIOLOGY

EDEM1 accelerates the trimming of  1,2-linked mannose on the C branch of N-glycans

(2010) N. Hosokawa et al.   GLYCOBIOLOGY

Structural Basis of Carbohydrate Recognition by Calreticulin

(2010) Guennadi Kozlov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Oligosaccharide Recognition of Misfolded Glycoproteins by OS-9 in ER-Associated Degradation

(2010) Tadashi Satoh et al.   MOLECULAR CELL

Basal autophagy is involved in the degradation of the ERAD component EDEM1

(2009) V. Le Fourn et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Human XTP3-B binds to  1-antitrypsin variant nullHong Kong via the C-terminal MRH domain in a glycan-dependent manner

(2009) D. Yamaguchi et al.   GLYCOBIOLOGY

Sugar-binding activity of the MRH domain in the ER  -glucosidase II   subunit is important for efficient glucose trimming

(2009) D. Hu et al.   GLYCOBIOLOGY

The sugar-binding ability of human OS-9 and its involvement in ER-associated degradation

(2009) Kaoru Mikami et al.   GLYCOBIOLOGY

Roles of Protein-disulfide Isomerase-mediated Disulfide Bond Formation of Yeast Mnl1p in Endoplasmic Reticulum-associated Degradation

(2009) Machiko Sakoh-Nakatogawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human OS-9, a Lectin Required for Glycoprotein Endoplasmic Reticulum-associated Degradation, Recognizes Mannose-trimmedN-Glycans

(2009) Nobuko Hosokawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

(2009) Simone Clerc et al.   JOURNAL OF CELL BIOLOGY

Glucosidase II β Subunit Modulates N-Glycan Trimming in Fission Yeasts and Mammals

(2009) Ivan D. Stigliano et al.   MOLECULAR BIOLOGY OF THE CELL

EDEM1 Recognition and Delivery of Misfolded Proteins to the SEL1L-Containing ERAD Complex

(2009) James H. Cormier et al.   MOLECULAR CELL

Human XTP3-B Forms an Endoplasmic Reticulum Quality Control Scaffold with the HRD1-SEL1L Ubiquitin Ligase Complex and BiP

(2008) Nobuko Hosokawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defining the Glycan Destruction Signal for Endoplasmic Reticulum-Associated Degradation

(2008) Erin M. Quan et al.   MOLECULAR CELL

OS-9 and GRP94 deliver mutant α1-antitrypsin to the Hrd1–SEL1L ubiquitin ligase complex for ERAD

(2008) John C. Christianson et al.   NATURE CELL BIOLOGY

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins

(2008) B. Mueller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER

(2008) R. Ushioda et al.   SCIENCE