C/EBP homologous protein-induced loss of intestinal epithelial stemness contributes to bile duct ligation-induced cholestatic liver injury in mice

The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice

(2017) Yongqing Wang et al.   HEPATOLOGY

Human Cystic Fibrosis Macrophages Have Defective Calcium-Dependent Protein Kinase C Activation of the NADPH Oxidase, an Effect Augmented byBurkholderia cenocepacia

(2017) Kaivon Assani et al.   JOURNAL OF IMMUNOLOGY

The role of PTEN in regulation of hepatic macrophages activation and function in progression and reversal of liver fibrosis

(2017) Yahui Cheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Gut-Liver Axis in Primary Sclerosing Cholangitis

(2016) Bertus Eksteen   Clinics in Liver Disease

Novel Aspects in the Management of Cholestatic Liver Diseases

(2016) Olivier Chazouillères   DIGESTIVE DISEASES

Primary sclerosing cholangitis is characterised by intestinal dysbiosis independent from IBD

(2016) João Sabino et al.   GUT

Epithelial ER Stress in Crohnʼs Disease and Ulcerative Colitis

(2016) Stewart S. Cao   INFLAMMATORY BOWEL DISEASES

Murine model of long-term obstructive jaundice

(2016) Hiroaki Aoki et al.   JOURNAL OF SURGICAL RESEARCH

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies

(2016) Jan Best et al.   PLoS One

Human Intestinal Barrier Function in Health and Disease

(2016) Julia König et al.   Clinical and Translational Gastroenterology

C/EBP homologous protein (CHOP) contributes to hepatocyte death via the promotion of ERO1α signalling in acute liver failure

(2015) Jianhua Rao et al.   BIOCHEMICAL JOURNAL

Cell death at the intestinal epithelial front line

(2015) Maria Eugenia Delgado et al.   FEBS Journal

Endoplasmic Reticulum Stress and Unfolded Protein Response in Inflammatory Bowel Disease

(2015) Stewart S. Cao   INFLAMMATORY BOWEL DISEASES

Alcoholic liver disease: mechanisms of injury and targeted treatment

(2015) Alexandre Louvet et al.   Nature Reviews Gastroenterology & Hepatology

Epithelial stem cells and intestinal cancer

(2015) Shawna Tan et al.   SEMINARS IN CANCER BIOLOGY

Endoplasmic Reticulum Stress in Intestinal Epithelial Cell Function and Inflammatory Bowel Disease

(2015) Katherine Luo et al.   Gastroenterology Research and Practice

Macrophages During the Fibrotic Process: M2 as Friend and Foe

(2015) Tarcio Teodoro Braga et al.   Frontiers in Immunology

The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity

(2014) Gisela Campos et al.   ARCHIVES OF TOXICOLOGY

Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2

(2014) Runping Liu et al.   HEPATOLOGY

Macrophage heterogeneity in liver injury and fibrosis

(2014) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

ER stress and hepatic lipid metabolism

(2014) Huiping Zhou et al.   Frontiers in Genetics

Enterohepatic bacterial infections dysregulate the FGF15-FGFR4 endocrine axis

(2013) Guillaume Romain et al.   BMC MICROBIOLOGY

C/EBP Homologous Protein (CHOP) Contributes to Suppression of Metabolic Genes during Endoplasmic Reticulum Stress in the Liver

(2013) Madhusudana R. Chikka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathological bacterial translocation in liver cirrhosis

(2013) Reiner Wiest et al.   JOURNAL OF HEPATOLOGY

Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration

(2013) Nick Barker   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The unfolded protein response and gastrointestinal disease

(2013) Arthur Kaser et al.   Seminars in Immunopathology

ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

(2013) Jarom Heijmans et al.   Cell Reports

The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor-induced hepatic lipotoxicity in mice

(2012) Yun Wang et al.   HEPATOLOGY

Endoplasmic Reticulum Stress Controls M2 Macrophage Differentiation and Foam Cell Formation

(2012) Jisu Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease

(2012) Derrick E. Fouts et al.   JOURNAL OF HEPATOLOGY

Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway

(2012) Jie Cao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Pathogenesis of Cholestatic Liver Disease and Therapeutic Approaches

(2010) Gideon M. Hirschfield et al.   GASTROENTEROLOGY

HIV Protease Inhibitors Induce Endoplasmic Reticulum Stress and Disrupt Barrier Integrity in Intestinal Epithelial Cells

(2009) Xudong Wu et al.   GASTROENTEROLOGY

Bile acids as regulatory molecules

(2009) Phillip B. Hylemon et al.   JOURNAL OF LIPID RESEARCH

CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury

(2008) Nobuyuki Tamaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY