Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2

Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis

(2013) Golnar Karimian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Bile Acids Affect the Growth of Human Cholangiocarcinoma via NF-kB Pathway

(2013) Jiaqi Dai et al.   CANCER INVESTIGATION

Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies

(2013) D Sia et al.   ONCOGENE

Acid ceramidase induces sphingosine kinase 1/S1P receptor 2-mediated activation of oncogenic Akt signaling

(2013) T H Beckham et al.   Oncogenesis

Classification, Diagnosis, and Management of Cholangiocarcinoma

(2012) Nataliya Razumilava et al.   Clinical Gastroenterology and Hepatology

Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network

(2012) Masayuki Nagahashi et al.   FASEB JOURNAL

Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents

(2012) Yuko Kageyama et al.   HEPATOLOGY

Novel organotypic culture model of cholangiocarcinoma progression

(2012) Deanna J. W. Campbell et al.   HEPATOLOGY RESEARCH

Sphingosine 1-phosphate receptors and sphingosine kinase 1: novel biomarkers for clinical prognosis in breast, prostate, and hematological cancers

(2012) Susan Pyne et al.   Frontiers in Oncology

A Mouse Model of Cholestasis-Associated Cholangiocarcinoma and Transcription Factors Involved in Progression

(2011) Heping Yang et al.   GASTROENTEROLOGY

Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes

(2011) Elaine Studer et al.   HEPATOLOGY

Impact of bile acids on the growth of human cholangiocarcinoma via FXR

(2011) Jiaqi Dai et al.   Journal of Hematology & Oncology

Differences in phosphatidylcholine and bile acids in bile from Egyptian and UK patients with and without cholangiocarcinoma

(2011) Mohamed S. Hashim AbdAlla et al.   HPB

Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2

(2010) Hyunho Yoon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential gene expression profiling of cultured neu-transformed versus spontaneously-transformed rat cholangiocytes and of corresponding cholangiocarcinomas

(2010) Catherine I. Dumur et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Sphingosine 1-phosphate (S1P)/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility

(2010) Changyong Li et al.   JOURNAL OF HEPATOLOGY

Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasion

(2010) Apaporn Menakongka   WORLD JOURNAL OF GASTROENTEROLOGY

S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor

(2009) Mei-Hong Li et al.   CANCER LETTERS

S1P/S1P2 Signaling Induces Cyclooxygenase-2 Expression in Wilms Tumor

(2009) Mei-Hong Li et al.   JOURNAL OF UROLOGY

Prevention of free fatty acid-induced hepatic lipotoxicity by 18β-glycyrrhetinic acid through lysosomal and mitochondrial pathways

(2008) Xudong Wu et al.   HEPATOLOGY

Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2

(2008) Hitoshi Ikeda et al.   JOURNAL OF LIPID RESEARCH