The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
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Title
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
Authors
Keywords
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Journal
Autophagy
Volume 9, Issue 11, Pages 1750-1757
Publisher
Informa UK Limited
Online
2013-11-09
DOI
10.4161/auto.26122
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Related references
Note: Only part of the references are listed.- Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
- (2013) A. Rana et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster
- (2012) I Pimenta de Castro et al. CELL DEATH AND DIFFERENTIATION
- Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
- (2012) Michael Lazarou et al. DEVELOPMENTAL CELL
- Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
- (2012) Andrew W Greene et al. EMBO REPORTS
- PINK1- and Parkin-mediated mitophagy at a glance
- (2012) Seok Min Jin et al. JOURNAL OF CELL SCIENCE
- Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation
- (2012) A. M. Nargund et al. SCIENCE
- Quality Control of Mitochondrial Proteostasis
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- Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
- (2010) Joo-Yong Lee et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
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- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
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- The Matrix Peptide Exporter HAF-1 Signals a Mitochondrial UPR by Activating the Transcription Factor ZC376.7 in C. elegans
- (2010) Cole M. Haynes et al. MOLECULAR CELL
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Regulation of OPA1 processing and mitochondrial fusion bym-AAA protease isoenzymes and OMA1
- (2009) Sarah Ehses et al. JOURNAL OF CELL BIOLOGY
- Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells
- (2009) Brian Head et al. JOURNAL OF CELL BIOLOGY
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
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