Shaping of interphase chromosomes by the microtubule network

Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins

(2015) Jennifer C. Harr et al.   JOURNAL OF CELL BIOLOGY

Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness

(2015) Takashi Furusawa et al.   Nature Communications

Adenomatous Polyposis Coli Interacts with Flap Endonuclease 1 to Block Its Nuclear Entry and Function

(2015) Aruna S. Jaiswal et al.   NEOPLASIA

Nucleocytoplasmic shuttling of the Duchenne muscular dystrophy gene product dystrophin Dp71d is dependent on the importin α/β and CRM1 nuclear transporters and microtubule motor dynein

(2014) R. Suárez-Sánchez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

(2014) Maria Thadani-Mulero et al.   CANCER RESEARCH

Activation of the γ-Tubulin Complex by the Mto1/2 Complex

(2014) Eric M. Lynch et al.   CURRENT BIOLOGY

Poly(ADP-ribose) polymerases in double-strand break repair: Focus on PARP1, PARP2 and PARP3

(2014) Carole Beck et al.   EXPERIMENTAL CELL RESEARCH

The Nuclear Localization of γ-Tubulin Is Regulated by SadB-mediated Phosphorylation

(2014) Greta Eklund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for nuclear envelope–bridging complexes in homology-directed repair

(2014) Rebecca K. Swartz et al.   MOLECULAR BIOLOGY OF THE CELL

The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration

(2014) Courtney R. Bone et al.   MOLECULAR BIOLOGY OF THE CELL

Local Translation and Retrograde Axonal Transport of CREB Regulates IL-6-Induced Nociceptive Plasticity

(2014) Ohannes K Melemedjian et al.   Molecular Pain

Tau promotes neurodegeneration through global chromatin relaxation

(2014) Bess Frost et al.   NATURE NEUROSCIENCE

Influenza A virus uses the aggresome processing machinery for host cell entry

(2014) Indranil Banerjee et al.   SCIENCE

Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells

(2014) D. Larrieu et al.   SCIENCE

A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions

(2014) Marie Violet et al.   Frontiers in Cellular Neuroscience

Signaling control of the constitutive androstane receptor (CAR)

(2014) Hui Yang et al.   Protein & Cell

Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL

(2014) Misty R Jenkins et al.   eLife

Identification of differential protein interactors of lamin A and progerin

(2014) Nard Kubben et al.   Nucleus

Physiological and pathological phosphorylation of tau by Cdk5

(2014) Taeko Kimura et al.   Frontiers in Molecular Neuroscience

Dynein Recruitment to Nuclear Pores Activates Apical Nuclear Migration and Mitotic Entry in Brain Progenitor Cells

(2013) Daniel Jun-Kit Hu et al.   CELL

The Herpesvirus VP1/2 Protein Is an Effector of Dynein-Mediated Capsid Transport and Neuroinvasion

(2013) Sofia V. Zaichick et al.   Cell Host & Microbe

The diverse functional LINCs of the nuclear envelope to the cytoskeleton and chromatin

(2013) Andrea Rothballer et al.   CHROMOSOMA

The Embryonic Linker Histone H1 Variant of Drosophila, dBigH1, Regulates Zygotic Genome Activation

(2013) Salvador Pérez-Montero et al.   DEVELOPMENTAL CELL

Axonal transcription factors: Novel regulators of growth cone-to-nucleus signaling

(2013) Sheng-Jian Ji et al.   Developmental Neurobiology

 -Catenin interacts with APC to regulate  -catenin proteolysis and transcriptional repression of Wnt target genes

(2013) S. H. Choi et al.   GENES & DEVELOPMENT

Interactions and functions of the adenomatous polyposis coli (APC) protein at a glance

(2013) S. Nelson et al.   JOURNAL OF CELL SCIENCE

Molecular mechanisms underlying RB protein function

(2013) Frederick A. Dick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Functions and mechanics of dynein motor proteins

(2013) Anthony J. Roberts et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kinesin KIFC1 actively transports bare double-stranded DNA

(2013) Francesca Farina et al.   NUCLEIC ACIDS RESEARCH

H1 histones: current perspectives and challenges

(2013) S. W. Harshman et al.   NUCLEIC ACIDS RESEARCH

Dynein Light Chain 1 (DYNLT1) Interacts with Normal and Oncogenic Nucleoporins

(2013) Nayan J. Sarma et al.   PLoS One

Hsc70 Is a Novel Interactor of NF-kappaB p65 in Living Hippocampal Neurons

(2013) Christin Klenke et al.   PLoS One

Active transport of RB protein from the nucleus to the cytoplasm as one of the development mechanisms of HER2-positive breast cancer

(2013) Artur Kowalik et al.   POLISH JOURNAL OF PATHOLOGY

Rapid mineralocorticoid receptor trafficking

(2013) M. Gekle et al.   STEROIDS

HIV trafficking in host cells: motors wanted!

(2013) Raphaël Gaudin et al.   TRENDS IN CELL BIOLOGY

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

(2013) E.-M. Mandelkow et al.   Cold Spring Harbor Perspectives in Medicine

Chromokinesins: localization-dependent functions and regulation during cell division

(2012) David Vanneste et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina

(2012) Joseph M. Zullo et al.   CELL

Microtubule dynamics alter the interphase nucleus

(2012) Gabi Gerlitz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional characterization of CP148, a novel key component for centrosome integrity in Dictyostelium

(2012) Oliver Kuhnert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Connecting the nucleus to the cytoskeleton by SUN–KASH bridges across the nuclear envelope

(2012) Erin C Tapley et al.   CURRENT OPINION IN CELL BIOLOGY

Axonal transcription factors signal retrogradely in lesioned peripheral nerve

(2012) Keren Ben-Yaakov et al.   EMBO JOURNAL

Cytotoxic T lymphocyte effector function is independent of nucleus-centrosome dissociation

(2012) Winnie W. Y. Lui-Roberts et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Highly acetylated tubulin permits enhanced interactions with and trafficking of plasmids along microtubules

(2012) M A Badding et al.   GENE THERAPY

On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1

(2012) X. Luo et al.   GENES & DEVELOPMENT

Lamin B Receptor Recognizes Specific Modifications of Histone H4 in Heterochromatin Formation

(2012) Yasuhiro Hirano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumors with Nonfunctional Retinoblastoma Protein Are Killed by Reduced γ-Tubulin Levels

(2012) Åsa Ehlén et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Csi1 links centromeres to the nuclear envelope for centromere clustering

(2012) Haitong Hou et al.   JOURNAL OF CELL BIOLOGY

Motor-driven motility of fungal nuclear pores organizes chromosomes and fosters nucleocytoplasmic transport

(2012) Gero Steinberg et al.   JOURNAL OF CELL BIOLOGY

Opposing microtubule motors drive robust nuclear dynamics in developing muscle cells

(2012) Meredith H. Wilson et al.   JOURNAL OF CELL SCIENCE

The where, when and how of microtubule nucleation - one ring to rule them all

(2012) N. Teixido-Travesa et al.   JOURNAL OF CELL SCIENCE

Cytoplasmic Trafficking, Endosomal Escape, and Perinuclear Accumulation of Adeno-Associated Virus Type 2 Particles Are Facilitated by Microtubule Network

(2012) P.-J. Xiao et al.   JOURNAL OF VIROLOGY

A Nuclear Localization Signal in Herpesvirus Protein VP1-2 Is Essential for Infection via Capsid Routing to the Nuclear Pore

(2012) F. Abaitua et al.   JOURNAL OF VIROLOGY

BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures

(2012) Daniël Splinter et al.   MOLECULAR BIOLOGY OF THE CELL

Multiple modes of cytoplasmic dynein regulation

(2012) Richard B. Vallee et al.   NATURE CELL BIOLOGY

New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?

(2012) Karolin Luger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions

(2012) Marcela Raices et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chromatin maintenance by a molecular motor protein

(2012) Manjari Mazumdar et al.   Nucleus

Barrier-to-Autointegration Factor influences specific histone modifications

(2012) Rocío Montes de Oca et al.   Nucleus

Assembly of the Base Excision Repair Complex on Abasic DNA and Role of Adenomatous Polyposis Coli on Its Functional Activity

(2011) Aruna S. Jaiswal et al.   BIOCHEMISTRY

Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems

(2011) Jane C Stinchcombe et al.   BMC BIOLOGY

Taxane-Induced Blockade to Nuclear Accumulation of the Androgen Receptor Predicts Clinical Responses in Metastatic Prostate Cancer

(2011) M. S. Darshan et al.   CANCER RESEARCH

A novel role of the chromokinesin Kif4A in DNA damage response

(2011) Guikai Wu et al.   CELL CYCLE

Microtubule-induced nuclear envelope fluctuations control chromatin dynamics in Drosophila embryos

(2011) Bernhard Hampoelz et al.   DEVELOPMENT

Coupling viruses to dynein and kinesin-1

(2011) Mark P Dodding et al.   EMBO JOURNAL

Nuclear localization of γ-tubulin affects E2F transcriptional activity and S-phase progression

(2011) Greta Höög et al.   FASEB JOURNAL

Transcription factor plasmid binding modulates microtubule interactions and intracellular trafficking during gene transfer

(2011) M A Badding et al.   GENE THERAPY

Inner nuclear membrane protein Ima1 is dispensable for intranuclear positioning of centromeres

(2011) Yasushi Hiraoka et al.   GENES TO CELLS

Adenomatous polyposis coli protein regulates the cellular response to DNA replication stress

(2011) Mariana G. Brocardo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Interplay between microtubule dynamics and intracellular organization

(2011) Hélène de Forges et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

APC as a mobile scaffold: Regulation and function at the nucleus, centrosomes, and mitochondria

(2011) Christina Lui et al.   IUBMB LIFE

Centrosome docking at the immunological synapse is controlled by Lck signaling

(2011) Andy Tsun et al.   JOURNAL OF CELL BIOLOGY

Samp1 is functionally associated with the LINC complex and A-type lamina networks

(2011) S. Gudise et al.   JOURNAL OF CELL SCIENCE

Nuclear γ-tubulin associates with nucleoli and interacts with tumor suppressor protein C53

(2011) Barbora Hořejší et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Interkinetic Nuclear Movement in the Ventricular Zone of the Cortex

(2011) Orly Reiner et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Effects of Microtubule Modulators on HIV-1 Infection of Transformed and Resting CD4 T Cells

(2011) A. Yoder et al.   JOURNAL OF VIROLOGY

Nuclear Envelope Disruption Involving Host Caspases Plays a Role in the Parvovirus Replication Cycle

(2011) S. Cohen et al.   JOURNAL OF VIROLOGY

Microtubule- and Dynein-Dependent Nuclear Trafficking of Rhesus Rhadinovirus in Rhesus Fibroblasts

(2011) W. Zhang et al.   JOURNAL OF VIROLOGY

Microtubule nucleation by γ-tubulin complexes

(2011) Justin M. Kollman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutation of RiceBC12/GDD1, Which Encodes a Kinesin-Like Protein That Binds to a GA Biosynthesis Gene Promoter, Leads to Dwarfism with Impaired Cell Elongation

(2011) Juan Li et al.   PLANT CELL

CD4+ T-cell synapses involve multiple distinct stages

(2011) H. Ueda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the Trail of the Glucocorticoid Receptor: Into the Nucleus and Back

(2011) Sofie Vandevyver et al.   TRAFFIC

Nuclear receptor coregulators merge transcriptional coregulation with epigenetic regulation

(2011) Shigeaki Kato et al.   TRENDS IN BIOCHEMICAL SCIENCES

Distinct association of the nuclear pore protein Nup153 with A- and B-type lamins

(2011) Teiba Al-Haboubi et al.   Nucleus

Characterization of nuclear factors modulating the apolipoprotein D promoter during growth arrest: Implication of PARP-1, APEX-1 and ERK1/2 catalytic activities

(2010) Louis-Charles Levros et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The nuclear import of the constitutive androstane receptor by importin/Ran-GTP systems

(2010) Yuichiro Kanno et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Single molecule studies of nucleocytoplasmic transport

(2010) Li-Chun Tu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The importin β binding domain as a master regulator of nucleocytoplasmic transport

(2010) Kaylen Lott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular basis for specificity of nuclear import and prediction of nuclear localization

(2010) Mary Marfori et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tubulin-Targeting Chemotherapy Impairs Androgen Receptor Activity in Prostate Cancer

(2010) M.-L. Zhu et al.   CANCER RESEARCH

Systematic Protein Location Mapping Reveals Five Principal Chromatin Types in Drosophila Cells

(2010) Guillaume J. Filion et al.   CELL

Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope

(2010) Maria Schneider et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional interactions between nucleoporins and chromatin

(2010) Yun Liang et al.   CURRENT OPINION IN CELL BIOLOGY

Loss of a DNA binding site within the tail of prelamin A contributes to altered heterochromatin anchorage by progerin

(2010) Francine Bruston et al.   FEBS LETTERS

Progress and prospects: nuclear import of nonviral vectors

(2010) A P Lam et al.   GENE THERAPY

Nuclear Tau, a Key Player in Neuronal DNA Protection

(2010) Audrey Sultan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinesin-1 and dynein at the nuclear envelope mediate the bidirectional migrations of nuclei

(2010) Heidi N. Fridolfsson et al.   JOURNAL OF CELL BIOLOGY

Efficient cell migration requires global chromatin condensation

(2010) G. Gerlitz et al.   JOURNAL OF CELL SCIENCE

Connecting the transcription site to the nuclear pore: a multi-tether process that regulates gene expression

(2010) G. Dieppois et al.   JOURNAL OF CELL SCIENCE

The nuclear envelope at a glance

(2010) K. L. Wilson et al.   JOURNAL OF CELL SCIENCE

A spatial model of cellular molecular trafficking including active transport along microtubules

(2010) A. Cangiani et al.   JOURNAL OF THEORETICAL BIOLOGY

P53 is transported into the nucleus via an Hsf1-dependent nuclear localization mechanism

(2010) Qiang Li et al.   MOLECULAR CARCINOGENESIS

The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets

(2010) Raga Krishnakumar et al.   MOLECULAR CELL

Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry

(2010) Daniël Splinter et al.   PLOS BIOLOGY

Plus- and Minus-End Directed Microtubule Motors Bind Simultaneously to Herpes Simplex Virus Capsids Using Different Inner Tegument Structures

(2010) Kerstin Radtke et al.   PLoS Pathogens

Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-α3 binding

(2009) N D Marchenko et al.   CELL DEATH AND DIFFERENTIATION

Adenovirus Transport via Direct Interaction of Cytoplasmic Dynein with the Viral Capsid Hexon Subunit

(2009) K. Helen Bremner et al.   Cell Host & Microbe

Dictyostelium Sun1 is a dynamic membrane protein of both nuclear membranes and required for centrosomal association with clustered centromeres

(2009) Irene Schulz et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes

(2009) Farhana Haque et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleocytoplasmic shuttling of soluble tubulin in mammalian cells

(2009) T. Akoumianaki et al.   JOURNAL OF CELL SCIENCE

Modulation of nucleocytoplasmic trafficking by retention in cytoplasm or nucleus

(2009) Daniela M. Roth et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The hsp90-FKBP52 Complex Links the Mineralocorticoid Receptor to Motor Proteins and Persists Bound to the Receptor in Early Nuclear Events

(2009) M. D. Galigniana et al.   MOLECULAR AND CELLULAR BIOLOGY

p150/Glued Modifies Nuclear Estrogen Receptor Function

(2009) Soo Jung Lee et al.   MOLECULAR ENDOCRINOLOGY

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Orchestrating nuclear envelope disassembly and reassembly during mitosis

(2009) Stephan Güttinger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice

(2009) Xiaochang Zhang et al.   NEURON

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

(2009) K. J. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stimulated nuclear translocation of NF-κB and shuttling differentially depend on dynein and the dynactin complex

(2009) Cynthia K. Shrum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic stabilization of microtubule dynamic instability by benomyl increases the nuclear transport of p53

(2008) Krishnan Rathinasamy et al.   BIOCHEMICAL PHARMACOLOGY

A Network of Nuclear Envelope Membrane Proteins Linking Centromeres to Microtubules

(2008) Megan C. King et al.   CELL

The nuclear envelope as an integrator of nuclear and cytoplasmic architecture

(2008) Melissa Crisp et al.   FEBS LETTERS

The APC Tumor Suppressor Inhibits DNA Replication by Directly Binding to DNA via Its Carboxyl Terminus

(2008) Jiang Qian et al.   GASTROENTEROLOGY

Ligand-dependent interaction between estrogen receptor and adenomatous polyposis coli

(2008) Alexander P. Kouzmenko et al.   GENES TO CELLS

Cyclic stretch-induced nuclear localization of transcription factors results in increased nuclear targeting of plasmids in alveolar epithelial cells

(2008) Anna P. Lam et al.   JOURNAL OF GENE MEDICINE

Interaction between Tumor Suppressor Adenomatous Polyposis Coli and Topoisomerase IIα: Implication for the G2/M Transition

(2008) Yang Wang et al.   MOLECULAR BIOLOGY OF THE CELL

EB1 acts as an oncogene via activating β-catenin/TCF pathway to promote cellular growth and inhibit apoptosis

(2008) Mei Liu et al.   MOLECULAR CARCINOGENESIS

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE

Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival

(2008) Llewellyn J. Cox et al.   NATURE CELL BIOLOGY

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli

(2008) A P Kouzmenko et al.   ONCOGENE

Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation

(2008) Yan Wei et al.   PLoS One

Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules

(2008) Q. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dictyostelium Sun-1 Connects the Centrosome to Chromatin and Ensures Genome Stability

(2008) Huajiang Xiong et al.   TRAFFIC

Cellular Proteins in Influenza Virus Particles

(2008) Megan L. Shaw et al.   PLoS Pathogens