Functions and mechanics of dynein motor proteins

Dynein Motion Switches from Diffusive to Directed upon Cortical Anchoring

(2013) Vaishnavi Ananthanarayanan et al.   CELL

Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine

(2013) Benjamin M. Stinson et al.   CELL

Molecular Adaptations Allow Dynein to Generate Large Collective Forces inside Cells

(2013) Arpan K. Rai et al.   CELL

Mechanisms of spindle positioning

(2013) Francis J. McNally   JOURNAL OF CELL BIOLOGY

Cargo Transport by Cytoplasmic Dynein Can Center Embryonic Centrosomes

(2013) Rafael A. Longoria et al.   PLoS One

Intraflagellar transport drives flagellar surface motility

(2013) Sheng Min Shih et al.   eLife

Cytoplasmic dynein

(2012) Victoria J. Allan   BIOCHEMICAL SOCIETY TRANSACTIONS

Cortical Dynein Controls Microtubule Dynamics to Generate Pulling Forces that Position Microtubule Asters

(2012) Liedewij Laan et al.   CELL

Lis1 Acts as a “Clutch” between the ATPase and Microtubule-Binding Domains of the Dynein Motor

(2012) Julie Huang et al.   CELL

Nucleotide-Dependent Control of Internal Strains in Ring-Shaped AAA+ Motors

(2012) Wonmuk Hwang et al.   Cellular and Molecular Bioengineering

Dynein Tethers and Stabilizes Dynamic Microtubule Plus Ends

(2012) Adam G. Hendricks et al.   CURRENT BIOLOGY

Microtubule-based transport in filamentous fungi

(2012) Martin J Egan et al.   CURRENT OPINION IN MICROBIOLOGY

Growth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cells

(2012) Timothy Mitchison et al.   Cytoskeleton

Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation

(2012) Jonne A Raaijmakers et al.   EMBO JOURNAL

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

Polarity and asymmetry in the arrangement of dynein and related structures in theChlamydomonasaxoneme

(2012) Khanh Huy Bui et al.   JOURNAL OF CELL BIOLOGY

Motor-driven motility of fungal nuclear pores organizes chromosomes and fosters nucleocytoplasmic transport

(2012) Gero Steinberg et al.   JOURNAL OF CELL BIOLOGY

Integrated control of axonemal dynein AAA+ motors

(2012) Stephen M. King   JOURNAL OF STRUCTURAL BIOLOGY

Cell cycle–regulated cortical dynein/dynactin promotes symmetric cell division by differential pole motion in anaphase

(2012) Elizabeth S. Collins et al.   MOLECULAR BIOLOGY OF THE CELL

Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

(2012) Ari J. Firestone et al.   NATURE

The 2.8 Å crystal structure of the dynein motor domain

(2012) Takahide Kon et al.   NATURE

Multiple modes of cytoplasmic dynein regulation

(2012) Richard B. Vallee et al.   NATURE CELL BIOLOGY

Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

(2012) Tomomi Kiyomitsu et al.   NATURE CELL BIOLOGY

Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

(2012) Emily A. Foley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Insights into dynein motor domain function from a 3.3-Å crystal structure

(2012) Helgo Schmidt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynein achieves processive motion using both stochastic and coordinated stepping

(2012) Weihong Qiu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-molecule observation of helix staggering, sliding, and coiled coil misfolding

(2012) Z. Xi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of the human cytoplasmic dynein complex

(2012) M. Trokter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two independent switches regulate cytoplasmic dynein's processivity and directionality

(2012) W. J. Walter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Microtubule Binding and Release by Dynein

(2012) W. B. Redwine et al.   SCIENCE

ATP-Driven Remodeling of the Linker Domain in the Dynein Motor

(2012) Anthony J. Roberts et al.   STRUCTURE

The mechanism of dynein motility: Insight from crystal structures of the motor domain

(2011) Carol Cho et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A unified taxonomy for ciliary dyneins

(2011) Erik F. Y. Hom et al.   Cytoskeleton

Coupling viruses to dynein and kinesin-1

(2011) Mark P Dodding et al.   EMBO JOURNAL

C-sequence of theDictyosteliumcytoplasmic dynein participates in processivity modulation

(2011) Naoki Numata et al.   FEBS LETTERS

Recombinant human cytoplasmic dynein heavy chain 1 and 2: Observation of dynein-2 motor activity in vitro

(2011) Muneyoshi Ichikawa et al.   FEBS LETTERS

B Cell Receptor-Mediated Antigen Gathering Requires Ubiquitin Ligase Cbl and Adaptors Grb2 and Dok-3 to Recruit Dynein to the Signaling Microcluster

(2011) Tim Schnyder et al.   IMMUNITY

Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation

(2011) Akiko Hashimoto-Tane et al.   IMMUNITY

Ciliogenesis: building the cell's antenna

(2011) Hiroaki Ishikawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynein struts its stuff

(2011) Neil Billington et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

X-ray structure of a functional full-length dynein motor domain

(2011) Takahide Kon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-electron tomography reveals conserved features of doublet microtubules in flagella

(2011) D. Nicastro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Dynein Motor Domain

(2011) A. P. Carter et al.   SCIENCE

Cytoplasmic Dynein Moves Through Uncoordinated Stepping of the AAA+ Ring Domains

(2011) M. A. DeWitt et al.   SCIENCE

LIS1 and NudE Induce a Persistent Dynein Force-Producing State

(2010) Richard J. McKenney et al.   CELL

Motor Number Controls Cargo Switching at Actin-Microtubule Intersections In Vitro

(2010) Harry W. Schroeder et al.   CURRENT BIOLOGY

Linking molecular motors to membrane cargo

(2010) Anna Akhmanova et al.   CURRENT OPINION IN CELL BIOLOGY

Flagellar and ciliary beating: the proven and the possible

(2010) C. B. Lindemann et al.   JOURNAL OF CELL SCIENCE

Nucleotide-induced global conformational changes of flagellar dynein arms revealed by in situ analysis

(2010) Tandis Movassagh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intracellular organelles mediate cytoplasmic pulling force for centrosome centration in the Caenorhabditis elegans early embryo

(2010) K. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoskeletal Forces Span the Nuclear Envelope to Coordinate Meiotic Chromosome Pairing and Synapsis

(2009) Aya Sato et al.   CELL

AAA+ Ring and Linker Swing Mechanism in the Dynein Motor

(2009) Anthony J. Roberts et al.   CELL

Structures of Asymmetric ClpX Hexamers Reveal Nucleotide-Dependent Motions in a AAA+ Protein-Unfolding Machine

(2009) Steven E. Glynn et al.   CELL

Electron-tomographic analysis of intraflagellar transport particle trains in situ

(2009) Gaia Pigino et al.   JOURNAL OF CELL BIOLOGY

Identification of dyneins that localize exclusively to the proximal portion of Chlamydomonas flagella

(2009) T. Yagi et al.   JOURNAL OF CELL SCIENCE

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding

(2009) Takahide Kon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The reciprocal coordination and mechanics of molecular motors in living cells

(2009) J. A. Laib et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thinking about flagellar oscillation

(2009) Charles J. Brokaw   CELL MOTILITY AND THE CYTOSKELETON

Function of dynein in budding yeast: Mitotic spindle positioning in a polarized cell

(2009) Jeffrey K. Moore et al.   CELL MOTILITY AND THE CYTOSKELETON

Clockwise Translocation of Microtubules by Flagellar Inner-Arm Dyneins In Vitro

(2008) Kenji Kikushima et al.   BIOPHYSICAL JOURNAL

LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein

(2008) Masami Yamada et al.   EMBO JOURNAL

Regulatory ATPase Sites of Cytoplasmic Dynein Affect Processivity and Force Generation

(2008) Carol Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct role of dynein motor in stable kinetochore-microtubule attachment, orientation, and alignment

(2008) Dileep Varma et al.   JOURNAL OF CELL BIOLOGY

Dynein drives nuclear rotation during forward progression of motile fibroblasts

(2008) J. R. Levy et al.   JOURNAL OF CELL SCIENCE

Direct observation of the mechanochemical coupling in myosin Va during processive movement

(2008) Takeshi Sakamoto et al.   NATURE

The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins

(2008) Xiaodong Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynein pulls microtubules without rotating its stalk

(2008) H. Ueno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Functional Role of Dynein's Microtubule-Binding Domain

(2008) A. P. Carter et al.   SCIENCE