Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells

Targeting Isoprenylcysteine Methylation Ameliorates Disease in a Mouse Model of Progeria

(2013) M. X. Ibrahim et al.   SCIENCE

Soft substrates normalize nuclear morphology and prevent nuclear rupture in fibroblasts from a laminopathy patient with compound heterozygous LMNA mutations

(2013) Chiara Tamiello et al.   Nucleus

Accumulation of the Inner Nuclear Envelope Protein Sun1 Is Pathogenic in Progeric and Dystrophic Laminopathies

(2012) Chia-Yen Chen et al.   CELL

Quantitative Chemical Proteomics Approach To Identify Post-translational Modification-Mediated Protein–Protein Interactions

(2012) Xiang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

(2012) Raphaël Rodriguez et al.   Nature Chemical Biology

Blocking farnesylation of the prelamin A variant in Hutchinson-Gilford progeria syndrome alters the distribution of A-type lamins

(2012) Yuexia Wang et al.   Nucleus

Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect

(2011) V. L. R. M. Verstraeten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleophosmin/B23 Inhibits Eg5-mediated Microtubule Depolymerization by Inactivating Its ATPase Activity

(2010) Guoxing Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon

(2009) Sarin Chimnaronk et al.   EMBO JOURNAL

NAT10, a nucleolar protein, localizes to the midbody and regulates cytokinesis and acetylation of microtubules

(2009) Qi Shen et al.   EXPERIMENTAL CELL RESEARCH

Depletion of nucleophosmin leads to distortion of nucleolar and nuclear structures in HeLa cells

(2008) Mohammed Abdullahel Amin et al.   BIOCHEMICAL JOURNAL

Chromatin changes induced by lamin A/C deficiency and the histone deacetylase inhibitor trichostatin A

(2008) G GALIOVA et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network: Cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone

(2008) Franco Chimenti et al.   JOURNAL OF MEDICINAL CHEMISTRY