Amino acid supplements and metabolic health: a potential interplay between intestinal microbiota and systems control

European consensus conference on faecal microbiota transplantation in clinical practice

(2017) Giovanni Cammarota et al.   GUT

The Microbiome and Risk for Obesity and Diabetes

(2017) Anthony L. Komaroff   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association Between Dietary Factors and Mortality From Heart Disease, Stroke, and Type 2 Diabetes in the United States

(2017) Renata Micha et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

(2017) Ruixin Liu et al.   NATURE MEDICINE

Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery

(2017) Derrick M Chu et al.   NATURE MEDICINE

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Supplementation with Essential Amino Acids in Middle Age Maintains the Health of Rat Kidney

(2017) G. Corsetti et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Essential Amino Acids Improve Insulin Activation of Akt/mTOR Signaling in Soleus Muscle of Aged Rats

(2017) V. Flati et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Metabolic shifts and structural changes in the gut microbiota upon branched-chain amino acid supplementation in middle-aged mice

(2016) Zhan Yang et al.   AMINO ACIDS

A Peculiar Formula of Essential Amino Acids Prevents Rosuvastatin Myopathy in Mice

(2016) Giuseppe D'Antona et al.   ANTIOXIDANTS & REDOX SIGNALING

Branched-chain amino acids differently modulate catabolic and anabolic states in mammals: a pharmacological point of view

(2016) Francesco Bifari et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

The Central Nervous System and the Gut Microbiome

(2016) Gil Sharon et al.   CELL

Branched-Chain Amino Acids and Insulin Metabolism: The Insulin Resistance Atherosclerosis Study (IRAS)

(2016) C. Christine Lee et al.   DIABETES CARE

The Metabolic Role of Gut Microbiota in the Development of Nonalcoholic Fatty Liver Disease and Cardiovascular Disease

(2016) Marco Sanduzzi Zamparelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Different Lipopolysaccharide Branched-Chain Amino Acids Modulate Porcine Intestinal Endogenous β-Defensin Expression through the Sirt1/ERK/90RSK Pathway

(2016) Man Ren et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome

(2016) Rachel J. Perry et al.   NATURE

A microbial perspective of human developmental biology

(2016) Mark R. Charbonneau et al.   NATURE

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance

(2016) Cholsoon Jang et al.   NATURE MEDICINE

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

(2016) Corinne Benakis et al.   NATURE MEDICINE

Signals from the gut microbiota to distant organs in physiology and disease

(2016) Bjoern O Schroeder et al.   NATURE MEDICINE

Role of gut microbiota in atherosclerosis

(2016) Annika Lindskog Jonsson et al.   Nature Reviews Cardiology

Gut microbiota influence stroke recovery in mice

(2016) Hemi Malkki   Nature Reviews Neurology

Modulation of type 1 and type 2 diabetes risk by the intestinal microbiome

(2016) Alexandra Paun et al.   PEDIATRIC DIABETES

Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes

(2016) Nicholas P. Semenkovich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The maternal microbiota drives early postnatal innate immune development

(2016) M. Gomez de Aguero et al.   SCIENCE

Comparison of Intradialytic Parenteral Nutrition with Glucose or Amino Acid Mixtures in Maintenance Hemodialysis Patients

(2016) Yan Liu et al.   Nutrients

The Emerging Role of Branched-Chain Amino Acids in Insulin Resistance and Metabolism

(2016) Mee-Sup Yoon   Nutrients

Human longevity: Genetics or Lifestyle? It takes two to tango

(2016) Giuseppe Passarino et al.   Immunity & Ageing

Branched-chain amino acids, mitochondrial biogenesis, and healthspan: an evolutionary perspective

(2016) Alessandra Valerio et al.   Aging-US

Effects of intraduodenal infusion of the branched-chain amino acid leucine on ad libitum eating, gut motor and hormone functions, and glycemia in healthy men

(2015) Robert E Steinert et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The effectiveness of leucine on muscle protein synthesis, lean body mass and leg lean mass accretion in older people: a systematic review and meta-analysis

(2015) Zhe-rong Xu et al.   BRITISH JOURNAL OF NUTRITION

Gut Microbiota Orchestrates Energy Homeostasis during Cold

(2015) Claire Chevalier et al.   CELL

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

(2015) Saeed Shoaie et al.   Cell Metabolism

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

(2015) Robert Caesar et al.   Cell Metabolism

Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome

(2015) Siegfried Ussar et al.   Cell Metabolism

Profile of plasma amino acids values as a predictor of sepsis in patients following living donor liver transplantation: Special reference to sarcopenia and postoperative early nutrition

(2015) Takeo Toshima et al.   HEPATOLOGY RESEARCH

Relationships between diet-related changes in the gut microbiome and cognitive flexibility

(2015) K.R. Magnusson et al.   NEUROSCIENCE

Sestrin2 is a leucine sensor for the mTORC1 pathway

(2015) R. L. Wolfson et al.   SCIENCE

Gut microbiota and aging

(2015) P. W. OToole et al.   SCIENCE

Human Milk: Mother Nature's Prototypical Probiotic Food?

(2015) Michelle K McGuire et al.   Advances in Nutrition

Nutrients and Muscle Disease

(2015) Enzo Nisoli et al.   Biomed Research International

Obesity, inflammation, and the gut microbiota

(2015) Amanda J Cox et al.   Lancet Diabetes & Endocrinology

Effects of Antibiotics on Human Microbiota and Subsequent Disease

(2014) Kristie M. Keeney et al.   Annual Review of Microbiology

Microbial Modulation of Insulin Sensitivity

(2014) Muhammad Tanweer Khan et al.   Cell Metabolism

Diet and Feeding Pattern Affect the Diurnal Dynamics of the Gut Microbiome

(2014) Amir Zarrinpar et al.   Cell Metabolism

Specialized Metabolites from the Microbiome in Health and Disease

(2014) Gil Sharon et al.   Cell Metabolism

Healthspan and Longevity in Mammals: A Family Game for Cellular Organelles?

(2014) Enzo Nisoli et al.   CURRENT PHARMACEUTICAL DESIGN

Impaired Adiponectin Signaling Contributes to Disturbed Catabolism of Branched-Chain Amino Acids in Diabetic Mice

(2014) Kun Lian et al.   DIABETES

Roux-en-Y Gastric Bypass Surgery, but Not Calorie Restriction, Reduces Plasma Branched-Chain Amino Acids in Obese Women Independent of Weight Loss or the Presence of Type 2 Diabetes

(2014) Mirjam A. Lips et al.   DIABETES CARE

The composition of the gut microbiota shapes the colon mucus barrier

(2014) H. E. Jakobsson et al.   EMBO REPORTS

Gut Microbes and the Brain: Paradigm Shift in Neuroscience

(2014) E. A. Mayer et al.   JOURNAL OF NEUROSCIENCE

Compositional dynamics of the human intestinal microbiota with aging: Implications for health

(2014) B. Lakshminarayanan et al.   Journal of Nutrition Health & Aging

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Stool Microbiota and Vaccine Responses of Infants

(2014) M. N. Huda et al.   PEDIATRICS

The Impact of Diet and Lifestyle on Gut Microbiota and Human Health

(2014) Michael Conlon et al.   Nutrients

Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans

(2014) J Fernandes et al.   Nutrition & Diabetes

Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit

(2013) Anita Wichmann et al.   Cell Host & Microbe

Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion

(2013) Hariom Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nutrient Sensing, Metabolism, and Cell Growth Control

(2013) Hai-Xin Yuan et al.   MOLECULAR CELL

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Dietary intervention impact on gut microbial gene richness

(2013) Aurélie Cotillard et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

(2013) J. G. M. Markle et al.   SCIENCE

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway

(2012) Jung Min Han et al.   CELL

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

Time series community genomics analysis reveals rapid shifts in bacterial species, strains, and phage during infant gut colonization

(2012) I. Sharon et al.   GENOME RESEARCH

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

(2012) Tiphaine Le Roy et al.   GUT

Comparison of high-protein diets and leucine supplementation in the prevention of metabolic syndrome and related disorders in mice

(2012) Anne Freudenberg et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Impact of leucine on energy balance

(2012) Liam McAllan et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Lymphotoxin regulates commensal responses to enable diet-induced obesity

(2012) Vaibhav Upadhyay et al.   NATURE IMMUNOLOGY

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Effects of a Leucine and Pyridoxine-Containing Nutraceutical on Fat Oxidation, and Oxidative and Inflammatory Stress in Overweight and Obese Subjects

(2012) Michael B. Zemel et al.   Nutrients

Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans

(2011) Reiner Jumpertz et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Intestinal absorption of water-soluble vitamins in health and disease

(2011) Hamid M. Said   BIOCHEMICAL JOURNAL

The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon

(2011) Dallas R. Donohoe et al.   Cell Metabolism

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

The effects of branched-chain amino acid granules on the accumulation of tissue triglycerides and uncoupling proteins in diet-induced obese mice

(2011) Mie Arakawa et al.   ENDOCRINE JOURNAL

The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

(2011) Premysl Bercik et al.   GASTROENTEROLOGY

The human gut virome: Inter-individual variation and dynamic response to diet

(2011) S. Minot et al.   GENOME RESEARCH

Branched-chain amino acids as pharmacological nutrients in chronic liver disease

(2011) Takumi Kawaguchi et al.   HEPATOLOGY

Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes

(2011) Tiffany D. Schaible et al.   HUMAN MOLECULAR GENETICS

Peripheral education of the immune system by colonic commensal microbiota

(2011) Stephanie K. Lathrop et al.   NATURE

Bifidobacteria can protect from enteropathogenic infection through production of acetate

(2011) Shinji Fukuda et al.   NATURE

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

(2011) Natalia Shulzhenko et al.   NATURE MEDICINE

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Amino Acids Oral Supplementation in Hemodialysis Patients: a Pilot Study

(2011) Piergiorgio Bolasco et al.   RENAL FAILURE

Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans

(2011) B. D. Muegge et al.   SCIENCE

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation

(2010) Claire Barbier de La Serre et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effects of oral amino acid supplementation on long-term-care-acquired infections in elderly patients

(2010) Roberto Aquilani et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice

(2010) Giuseppe D'Antona et al.   Cell Metabolism

Minireview: Update on Incretin Biology: Focus on Glucagon-Like Peptide-1

(2010) Patricia L. Brubaker   ENDOCRINOLOGY

Effects of gut microbiota on obesity and atherosclerosis via modulation of inflammation and lipid metabolism

(2010) R. Caesar et al.   JOURNAL OF INTERNAL MEDICINE

Higher Branched-Chain Amino Acid Intake Is Associated with a Lower Prevalence of Being Overweight or Obese in Middle-Aged East Asian and Western Adults

(2010) Li‐Qiang Qin et al.   JOURNAL OF NUTRITION

Branched-chain amino acids protect against dexamethasone-induced soleus muscle atrophy in rats

(2010) Daisuke Yamamoto et al.   MUSCLE & NERVE

Viruses in the faecal microbiota of monozygotic twins and their mothers

(2010) Alejandro Reyes et al.   NATURE

Characterization of the Oral Fungal Microbiome (Mycobiome) in Healthy Individuals

(2010) Mahmoud A. Ghannoum et al.   PLoS Pathogens

Topical application of dressing with amino acids improves cutaneous wound healing in aged rats

(2009) Giovanni Corsetti et al.   ACTA HISTOCHEMICA

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

The core gut microbiome, energy balance and obesity

(2009) Peter J. Turnbaugh et al.   JOURNAL OF PHYSIOLOGY-LONDON

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Community Variation in Human Body Habitats Across Space and Time

(2009) E. K. Costello et al.   SCIENCE

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

(2009) P. J. Turnbaugh et al.   Science Translational Medicine

Amino Acid Supplementation Counteracts Metabolic and Functional Damage in the Diabetic Rat Heart

(2008) Maria Antonietta Pellegrino et al.   AMERICAN JOURNAL OF CARDIOLOGY

Amino Acids and Mitochondrial Biogenesis

(2008) Enzo Nisoli et al.   AMERICAN JOURNAL OF CARDIOLOGY

Oral Amino Acid Supplementation Counteracts Age-Induced Sarcopenia in Elderly Rats

(2008) Orietta Pansarasa et al.   AMERICAN JOURNAL OF CARDIOLOGY

Improvement of Blood Glucose Control and Insulin Sensitivity During a Long-Term (60 Weeks) Randomized Study with Amino Acid Dietary Supplements in Elderly Subjects with Type 2 Diabetes Mellitus

(2008) Sebastiano B. Solerte et al.   AMERICAN JOURNAL OF CARDIOLOGY

Morphometric Changes Induced by Amino Acid Supplementation in Skeletal and Cardiac Muscles of Old Mice

(2008) Giovanni Corsetti et al.   AMERICAN JOURNAL OF CARDIOLOGY

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

Dairy protein and leucine alter GLP-1 release and mRNA of genes involved in intestinal lipid metabolism in vitro

(2008) Qixuan Chen et al.   NUTRITION

Developmental Changes of Gut Microflora and Enzyme Activity in Rat Pups Exposed to Fat-rich Diet

(2008) Štefan Mozeš et al.   Obesity

Amino Acid Transport Across Mammalian Intestinal and Renal Epithelia

(2008) Stefan Bröer   PHYSIOLOGICAL REVIEWS

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA