Article
Cell Biology
Jacopo Di Gregorio, Sabrina Petricca, Roberto Iorio, Elena Toniato, Vincenzo Flati
Summary: Metabolic alterations, including enhanced aerobic glycolysis, oxidative phosphorylation, gluconeogenesis, and fatty acid beta-oxidation, play crucial roles in the development and survival of cancers.
EUROPEAN JOURNAL OF CELL BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Luciane C. Alberici, Helena C. F. Oliveira
Summary: Changes in plasma triglyceride metabolism and dietary fatty acid types are major contributors to metabolic and cardiovascular diseases. Mitochondrial adaptive responses play a crucial role in increasing energy expenditure and reducing oxidative stress in facing metabolic challenges.
ANTIOXIDANTS & REDOX SIGNALING
(2022)
Review
Cell Biology
Humberto De Vitto, Danushka B. Arachchige, Brian C. Richardson, Jarrod B. French
Summary: This review highlights the essential role of nucleotides in cell growth and survival, as well as the impact of purine and mitochondrial metabolism in cancer progression, particularly in ovarian cancer. It also addresses the importance of metabolic rewiring in cancer and the potential utilization of purine synthesis and mitochondrial inhibitors for cancer treatment in the evolving landscape.
Article
Neurosciences
Maurizio Ragni, Francesca Fenaroli, Chiara Ruocco, Agnese Segala, Giuseppe D'Antona, Enzo Nisoli, Alessandra Valerio
Summary: Mitochondrial dysfunction is involved in aging and neurodegenerative diseases, including ischemic stroke. Non-pharmacological interventions like exercise can prevent stroke, but they are challenging for older individuals. This study suggests that dietary supplementation with a balanced essential amino acid mixture (BCAAem) can mimic the effects of exercise on brain mitochondria and prevent neurodegeneration. BCAAem treatment directly promotes mitochondrial biogenesis and protects cortical neurons from ischemic damage. The mTOR and eNOS signaling pathways are involved in the effects of BCAAem. It is proposed that BCAAem supplementation can be an alternative to exercise in preventing brain mitochondrial dysfunction and aiding recovery after cerebral ischemia.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Cell Biology
Kiyoto Nishi, Akira Yoshii, Lauren Abell, Bo Zhou, Ricardo Frausto, Julia Ritterhoff, Timothy S. McMillen, Ian Sweet, Yibin Wang, Chen Gao, Rong Tian
Summary: It was found that deficiency of Ppm1k leads to reduced metabolism of branched-chain amino acids (BCAAs) and protects against obesity-induced glucose intolerance. Accumulation of branched-chain keto acids (BCKAs) inhibits glucose production in liver cells. It was observed that BCKAs suppress the activity of liver mitochondrial pyruvate carrier (MPC) and pyruvate-supported respiration. Selective suppression of pyruvate-supported gluconeogenesis was seen in Ppm1k-deficient mice and could be restored through pharmacological activation of BCKA catabolism by BT2. Furthermore, liver MPC was found to be most sensitive to circulating BCKA levels, making it a sensor of BCAA metabolism.
Article
Immunology
Chunxiao Mou, Yuxi Wang, Shuonan Pan, Kaichuang Shi, Zhenhai Chen
Summary: This research investigated the cell apoptosis induced by Porcine sapelovirus (PSV) infection and its underlying mechanisms. The results showed typical features of apoptosis, such as nuclear condensation and fragmentation, after infection. Cell apoptosis was confirmed by analyzing apoptotic rates, caspase activation, and PARP1 cleavage. The study found that 2A protein encoded by PSV was a crucial factor in inducing the mitochondrial apoptotic pathway.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Yutaka Matsunaga, Yuki Tamura, Kenya Takahashi, Yu Kitaoka, Yumiko Takahashi, Daisuke Hoshino, Tomoyasu Kadoguchi, Hideo Hatta
Summary: This study found that BCAA supplementation can suppress the detraining-induced reduction of mitochondrial content, partly through inhibiting mitophagy.
Review
Biochemistry & Molecular Biology
Nadia Turton, Neve Cufflin, Mollie Dewsbury, Olivia Fitzpatrick, Rahida Islam, Lowidka Linares Watler, Cara McPartland, Sophie Whitelaw, Caitlin Connor, Charlotte Morris, Jason Fang, Ollie Gartland, Liv Holt, Iain P. Hargreaves
Summary: Mitochondrial respiratory chain (MRC) disorders are complex diseases that require a multidisciplinary approach in diagnosis. Biochemical investigations, such as metabolite analysis, measurement of lactate, pyruvate, and amino acid levels, as well as assessment of hormone-like cytokines and evidence of oxidative stress, play important roles in diagnosing MRC dysfunction. However, at present, there is a lack of reliable biomarkers for evaluating evidence of MRC dysfunction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biology
Johanna Abrigo, Hugo Olguin, Franco Tacchi, Josue Orozco-Aguilar, Mayalen Valero-Breton, Jorge Soto, Mauricio Castro-Sepulveda, Alvaro A. Elorza, Felipe Simon, Claudio Cabello-Verrugio
Summary: Bile acids can lead to mitochondrial dysfunction by affecting mitochondrial biogenesis and altering mitochondrial function, resulting in impaired energy production and oxidative stress, which ultimately leads to muscle weakness.
BIOLOGICAL RESEARCH
(2023)
Review
Endocrinology & Metabolism
Chiara Ruocco, Agnese Segala, Alessandra Valerio, Enzo Nisoli
Summary: Restriction and supplementation of specific amino acids or BCAAs can improve metabolic homeostasis, energy balance, and health span. Recent research shows that a mixture of EAAs and BCAAs can extend healthy lifespan by promoting mitochondrial biogenesis and activating antioxidant defense systems. New formulas enriched with Krebs cycle substrates may be more efficient than BCAA-enriched mixtures in improving mitochondrial health and overall well-being.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
(2021)
Article
Cell Biology
Jia Guo, Feng Zhou, Zhi Liu, Yuan Cao, Wanming Zhao, Zheru Zhang, Qiming Zhai, Yan Jin, Bei Li, Fang Jin
Summary: Combining exosomes with dental pulp stem cells (DPSCs) has a remarkable effect on bone regeneration. Exosomes promote osteogenic differentiation of DPSCs by transferring mitochondrial transcription factor A (TFAM) mRNA and enhancing glutamate metabolism and oxidative phosphorylation (OXPHOS) activity. This study provides a new potential strategy to improve DPSC-based bone regenerative treatment.
CELL PROLIFERATION
(2022)
Review
Neurosciences
Jonathan M. Memme, Avigail T. Erlich, David A. Hood, Geetika Phukan
Summary: Mitochondrial health is crucial for cellular function and overall vitality, with skeletal muscle serving as a key model tissue for studying mitochondrial adaptations. The plasticity of mitochondria allows for adjustments in response to exercise, contributing to metabolic health in individuals with various diseases and aging. Further research into mitochondrial turnover mechanisms in muscle could provide therapeutic targets for improving health and longevity in aging populations.
JOURNAL OF PHYSIOLOGY-LONDON
(2021)
Review
Biochemistry & Molecular Biology
Keeley G. Hewton, Amritpal S. Johal, Seth J. Parker
Summary: Mitochondria are essential organelles in coordinating various metabolic and biological functions within cells. Amino acids play a crucial role in mitochondrial bioenergetics, biosynthesis, and homeostasis, requiring specific transporters for import and exchange across membranes. Studying mitochondrial amino acid metabolism provides insights into the role of transporters in compartmentalized metabolism.
Article
Cell Biology
Mikael Flockhart, Lina C. Nilsson, Senna Tais, Bjorn Ekblom, William Apro, Filip J. Larsen
Summary: Exercise training positively affects metabolic health, but excess exercise may lead to reduced mitochondrial function and impaired glucose tolerance. Studies have shown that world-class endurance athletes have issues with glucose control compared to matched control groups.
Article
Endocrinology & Metabolism
Daniel Ferguson, Sophie J. Eichler, Nicole K. H. Yiew, Jerry R. Colca, Kevin Cho, Gary J. Patti, Trevor M. Shew, Andrew J. Lutkewitte, Sandip Mukherjee, Kyle S. McCommis, Natalie M. Niemi, Brian N. Finck
Summary: The study evaluated the effects of MPC inhibitors (MPCi) on branched chain amino acid (BCAA) metabolism and found that MPCi can lower plasma BCAA concentrations and activate AMPK and mTOR signaling pathways. However, the effects on glucose homeostasis may be separate from BCAA concentrations.
MOLECULAR METABOLISM
(2023)
Article
Endocrinology & Metabolism
Gianluca Iacobellis, Alexis Elias Malavazos, Sara Basilico, Silvia Tresoldi, Rocco Francesco Rinaldo, Carola Dubini, Gloria Capitanio, Francesca Serpi, Simone Schiaffino, Omar Alessandro Oliva, Maurizio Cariati, Lelio Morricone, Stefano Centanni, Francesco Sardanelli, Michele Carruba, Massimiliano Marco Corsi Romanelli, Francesco Secchi
Summary: This study found that the inflammation level of EAT in COVID-19 patients upon admission was significantly correlated with blood glucose levels, interleukin 6, troponin T levels, and waist circumference. After treatment, dexamethasone therapy was associated with a significant reduction of EAT inflammation, while SAT did not change. Therefore, anti-inflammatory therapies targeting visceral fat may be helpful in the treatment of COVID-19.
Review
Medicine, General & Internal
Ulderico Freo, Chiara Ruocco, Alessandra Valerio, Irene Scagnol, Enzo Nisoli
Summary: Paracetamol is a common analgesic drug with therapeutic efficacy in acute and chronic pain conditions. However, concerns have been raised about its efficacy and hepatic toxicity. Therefore, dose adjustment based on individual conditions and genotyping may improve its effectiveness and safety.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Endocrinology & Metabolism
Georgia Colleluori, Laura Graciotti, Mauro Pesaresi, Angelica Di Vincenzo, Jessica Perugini, Eleonora Di Mercurio, Sara Caucci, Patrizia Bagnarelli, Cristina M. Zingaretti, Enzo Nisoli, Stefano Menzo, Adriano Tagliabracci, Annie Ladoux, Christian Dani, Antonio Giordano, Saverio Cinti
Summary: This study confirms the presence of lung fat embolism in COVID-19 patients and describes novel COVID-19-related features possibly contributing to the unfavorable prognosis in individuals with COVID-19 and obesity.
INTERNATIONAL JOURNAL OF OBESITY
(2022)
Correction
Cardiac & Cardiovascular Systems
Alexis E. Malavazos, Gloria Capitanio, Valentina Milani, Federico Ambrogi, Irene A. Matelloni, Sara Basilico, Carola Dubini, Francesca M. Sironi, Elisabetta Stella, Silvana Castaldi, Francesco Secchi, Lorenzo Menicanti, Gianluca Iacobellis, Massimiliano M. Corsi Romanelli, Michele O. Carruba, Lelio F. Morricone
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Endocrinology & Metabolism
Alexis Elias Malavazos, Sara Basilico, Gianluca Iacobellis, Valentina Milani, Rosanna Cardani, Federico Boniardi, Carola Dubini, Ilaria Prandoni, Gloria Capitanio, Laura Valentina Renna, Sara Boveri, Matteo Carrara, Giovanni Spuria, Teresa Cuppone, Aurelia D'acquisto, Luca Carpinelli, Marta Sacchi, Lelio Morricone, Francesco Secchi, Elena Costa, Lorenzo Menicanti, Enzo Nisoli, Michele Carruba, Federico Ambrogi, Massimiliano Marco Corsi Romanelli
Summary: People with abdominal obesity may have a weaker antibody response to SARS-CoV-2 vaccines, indicating the need for booster vaccines, especially for those with abdominal obesity.
Article
Cardiac & Cardiovascular Systems
Maurizio Ragni, Carolina Magdalen Greco, Arianna Felicetta, Shuxun Vincent Ren, Paolo Kunderfranco, Chiara Ruocco, Pierluigi Carullo, Veronica Larcher, Laura Tedesco, Ilenia Severi, Antonio Giordano, Saverio Cinti, Alessandra Valerio, Haipeng Sun, Yibin Wang, Chen Gao, Gianluigi Condorelli, Enzo Nisoli
Summary: A designer diet with essential amino acids substituted for protein has shown remarkable therapeutic effects on heart failure, improving glucose metabolism and mitochondrial fuel oxidation.
CARDIOVASCULAR RESEARCH
(2023)
Review
Oncology
Maurizio Ragni, Claudia Fornelli, Enzo Nisoli, Fabio Penna
Summary: Cancer metabolism offers new insights into identifying vulnerabilities of cancer cells, targeting alterations in amino acid metabolism to limit tumor growth can impact the cancer-host metabolism and patient outcome; Cachexia, a common syndrome in cancer patients, may be improved by appropriate amino acid interventions to enhance nutritional status and anti-cancer treatment effectiveness.
Article
Cardiac & Cardiovascular Systems
Alexis Elias Malavazos, Gianluca Iacobellis, Elena Dozio, Sara Basilico, Angelica Di Vincenzo, Carola Dubini, Lorenzo Menicanti, Elena Vianello, Chiara Meregalli, Chiara Ruocco, Maurizio Ragni, Francesco Secchi, Pietro Spagnolo, Serenella Castelvecchio, Lelio Morricone, Silvio Buscemi, Antonio Giordano, Jeffrey J. Goldberger, Michele Carruba, Saverio Cinti, Massimiliano Marco Corsi Romanelli, Enzo Nisoli
Summary: Human epicardial adipose tissue (EAT) is a unique and multifunctional fat compartment of the heart that can directly interact with the myocardium. It plays a key role in the development and progression of coronary artery disease, atrial fibrillation, and heart failure. Targeting EAT through G-protein-coupled receptors, such as GLP-1R agonists, can be a novel therapeutic approach.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Amelia Brunani, Raffaella Cancello, Michele Gobbi, Elisa Lucchetti, Giulia Di Guglielmo, Sabrina Maestrini, Stefania Cattaldo, Paolo Pitera, Chiara Ruocco, Alessandra Milesi, Alessandra Valerio, Paolo Capodaglio, Enzo Nisoli
Summary: This study aimed to assess the impact of protein or amino acid supplements on muscle mass loss in middle-aged men. The results showed that the PD-E07 supplement group had a notable increase in muscle mass compared to the control group, while the protein and BCAA supplement groups did not exhibit a significant difference. Therefore, amino acid-based supplements may effectively mitigate the loss of muscle mass during weight reduction.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Laura Tedesco, Fabio Rossi, Chiara Ruocco, Maurizio Ragni, Michele O. Carruba, Alessandra Valerio, Enzo Nisoli
Summary: Skin deterioration is caused by dermatological disorders, environmental conditions, and aging processes. Implementing healthy nutrition, maintaining a balanced diet, and supplying adequate food supplements can effectively supervise the skin aging process. Comparing three substances (H-Pro-Hyp-OH peptide, hydrolyzed collagen, and a mixture of six amino acids), the study found that the mixture of six amino acids exerts beneficial effects on human skin fibroblasts, promoting the gene expression of elastin, fibronectin, and collagen 1.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
(2022)
Letter
Psychiatry
Michele O. Carruba, Alexis Malavazos, Alessandra Valerio, Enzo Nisoli
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2022)
Review
Psychiatry
Michele O. Carruba, Antonio Caretto, Antonino De Lorenzo, Giuseppe Fatati, Andrea Ghiselli, Lucio Lucchin, Claudio Maffeis, Alexis Malavazos, Giuseppe Malfi, Enrica Riva, Chiara Ruocco, Ferruccio Santini, Marco Silano, Alessandra Valerio, Andrea Vania, Enzo Nisoli
Summary: This paper focuses on comparing two front-of-pack nutritional labels, the NutrInform Battery and the Nutri-Score system, emphasizing that the NutrInform Battery may help consumers better understand nutritional information compared to the Nutri-Score system, potentially improving dietary choices.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2022)
Article
Psychiatry
Alexis Elias Malavazos, Francesco Secchi, Sara Basilico, Gloria Capitanio, Sara Boveri, Valentina Milani, Carola Dubini, Simone Schiaffino, Lelio Morricone, Chiara Foschini, Giulia Gobbo, Rosangela Piccinni, Alessandro Saibene, Francesco Sardanelli, Lorenzo Menicanti, Marco Guazzi, Chuanhui Dong, Massimiliano Marco Corsi Romanelli, Michele Carruba, Gianluca Iacobellis
Summary: Abdominal obesity is more strongly associated with high CXR severity scores in hospitalized COVID-19 patients than BMI-based obesity. Regular measurement of waist circumference and close monitoring of patients with abdominal obesity is recommended.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2022)
Article
Psychiatry
Enzo Nisoli, Saverio Cinti, Alessandra Valerio
Summary: During the COVID-19 pandemic, clinicians have been working hard to find effective treatments for the disease, with gastrointestinal disturbances being a notable clinical presentation. Through evidence from clinical and basic research, a novel hypothesis has been proposed to improve symptoms in COVID-19 patients by increasing amino acid supplements.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Jose E. Exaire, Timothy A. Mixon
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia
Summary: Dyslipidemia is common in Paralympic athletes, with lipid levels influenced by the type of disability and sporting discipline.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Murat Ziyrek, Ertugrul Okuyan
Summary: This study aimed to evaluate the predictive value of the GRACE risk score in acute pulmonary embolism (PE) patients for 30-day mortality and the need for thrombolytic treatment. The study found that the GRACE risk score, along with the PESI score, were independent risk factors associated with 30-day mortality and the need for thrombolytic treatment. The GRACE risk score showed high sensitivity and specificity in predicting mortality, and its combination with the PESI score helped define high-risk PE patients and predict poor prognosis.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Tom Kai Ming Wang, Reza Reyaldeen, Kevser Akyuz, Zoran B. Popovic, A. Marc Gillinov, Bo Xu, Brian P. Griffin, Milind Y. Desai
Summary: Transthoracic echocardiography (TTE) is commonly used to evaluate isolated tricuspid regurgitation (TR), but there is limited research comparing its quantification with magnetic resonance imaging (MRI). In this study, a novel TTE algorithm was developed to identify severe TR based on TTE parameters. The algorithm had a higher accuracy than the current guidelines' criteria in detecting severe TR by MRI.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Enkhtsogt Sainbayar, Ramzi Ibrahim, Hoang Nhat Pham, Wisam Beauti, Mahek Shahid, Natalie Hickerson, Mohammed Salih, Joao Paulo Ferreira, Mamas A. Mamas
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Richard E. Casazza, Hymie Chera, Carlos Adolfo Rodriguez, Sergey Ayzenberg
Summary: This article presents a case of a patient with known situs inversus who underwent cardiac catheterization and was found to have chronic total occlusion in the right coronary artery. Situs inversus is a rare congenital abnormality characterized by the inverted position of chest and abdominal organs. Cardiac catheterization is uncommon in patients with this particular abnormality, highlighting the importance of customizing techniques to engage coronary arteries and optimize guide support for percutaneous coronary intervention if needed.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Bulbul Ahmed, Melissa G. Farb, Shakun Karki, Sophia D'Alessandro, Niloo M. Edwards, Noyan Gokce
Summary: This study evaluated the angiogenic capacity of adipose tissue in patients undergoing cardiac surgeries and found that patients with coronary artery disease (CAD) had reduced angiogenic capacity in their pericardial adipose tissue. Gene expression analysis revealed upregulated expression of the anti-angiogenic gene TSP-1 in CAD patients, with no significant differences in other angiogenic factors. Additionally, inhibiting TSP-1 expression significantly improved angiogenic deficiency in CAD patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moshe Rav-Acha, Orli Wube, Oholi Tovia Brodie, Yoav Michowitz, Michael Ilan, Tal Ovdat, Robert Klempfner, Mahmud Suleiman, Ilan Goldenberg, Michael Glikson
Summary: The current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) for patients with symptomatic heart failure (HF) and low left ventricular ejection fraction. However, not all patients will benefit from ICD treatment. This study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to predict the survival benefit of prophylactic ICDs in patients with HF. The results showed that different risk subgroups had varying levels of ICD survival benefit.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ariel Banai, Rachel Retsky, Lior Lupu, Erez Levi, David Zahler, Omri Feder, Roei Merin, Yan Topilsky, Raphael Rosso, Shmuel Banai, Sami Viskin, Ehud Chorin
Summary: This study aims to evaluate the association between electromechanical window (EMW) and ventricular tachyarrhythmias in patients with Takotsubo syndrome (TTS). The study found that TTS patients had a lower EMW value, which was associated with an increased risk of ventricular tachyarrhythmias.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Harun Kundi, Kobina Hagan, Tamer Yahya, Garima Sharma, Sadeer Al-Kindi, Zulqarnain Javed, Khurram Nasir
Summary: Using latent class analysis (LCA), the study identified clinical, demographic, and social subphenotypes in ASCVD population and assessed the risk of all-cause and cardiovascular mortality across different socioclinical classes. The results showed that the younger, female, non-Hispanic Black or Hispanic individuals with a high burden of co-morbidities and unfavorable social determinants of health had the highest risk of mortality in the identified latent classes.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moises A. Vasquez, Mina Iskander, Mohammed Mustafa, Juan A. Quintero-Martinez, Antonio Luna, Joel Mintz, Jose Noy, Juan Uribe, Ivan Mijares, Eduardo de Marchena, Yiannis S. Chatzizisis
Summary: The benefits of pericardiocentesis (PC) in patients with pulmonary hypertension (PH) and pericardial effusions are unclear. The study found that PC in PH patients is associated with higher in-hospital mortality and rates of cardiovascular complications.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ken Kuwajima, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, Takahiro Shiota
Summary: After cardiac surgery, the longitudinal function of the right ventricle and left ventricle is reduced, despite preserved global functions. In particular, tricuspid annular plane systolic excursion (TAPSE) remains decreased after surgery.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Min -Jung Kim, Robert H. Aseltine Jr, Sara R. Tabtabai
Summary: This study evaluated the rates and causes of 30-day readmissions after discharge for heart failure (HF) as a primary and secondary diagnosis. The findings indicate that efforts to reduce readmission rates should include patients with secondary HF diagnosis, and surveillance should extend to 2 weeks postdischarge to identify at-risk patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ya He, Jianzhong Zhou
Summary: This study aimed to examine the relation between reverse septal curvature (RSC) and nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM). The study found that patients with RSC were younger and had a higher incidence of NSVT, and RSC was identified as a strong independent risk factor for NSVT.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)