Human longevity: Genetics or Lifestyle? It takes two to tango

Interventions to Slow Aging in Humans: Are We Ready?

(2015) Valter D. Longo et al.   AGING CELL

Accelerated epigenetic aging in Down syndrome

(2015) Steve Horvath et al.   AGING CELL

The cerebellum ages slowly according to the epigenetic clock

(2015) Steve Horvath et al.   Aging-US

Population-specific association of genes for telomere-associated proteins with longevity in an Italian population

(2015) Paolina Crocco et al.   BIOGERONTOLOGY

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and AngiogenesisNovelty and Significance

(2015) Francesco Villa et al.   CIRCULATION RESEARCH

DNA methylation age of blood predicts all-cause mortality in later life

(2015) Riccardo E Marioni et al.   GENOME BIOLOGY

Male longevity in Sardinia, a review of historical sources supporting a causal link with dietary factors

(2014) G M Pes et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis

(2014) Birgit Debrabant et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A systems biology analysis of the unique and overlapping transcriptional responses to caloric restriction and dietary methionine restriction in rats

(2014) Sujoy Ghosh et al.   FASEB JOURNAL

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

(2014) Joris Deelen et al.   HUMAN MOLECULAR GENETICS

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

(2013) Marian Beekman et al.   AGING CELL

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

(2013) Nicola Raule et al.   AGING CELL

The Okinawan Diet: Health Implications of a Low-Calorie, Nutrient-Dense, Antioxidant-Rich Dietary Pattern Low in Glycemic Load

(2013) D. Craig Willcox et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

The GH/IGF-1 axis in ageing and longevity

(2013) Riia K. Junnila et al.   Nature Reviews Endocrinology

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Genetic Signatures of Exceptional Longevity in Humans

(2012) Paola Sebastiani et al.   PLoS One

The application of genetics approaches to the study of exceptional longevity in humans: potential and limitations

(2012) Anna Ferrario et al.   Immunity & Ageing

Global DNA methylation in old subjects is correlated with frailty

(2011) Dina Bellizzi et al.   AGE

Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis

(2011) Mette Soerensen et al.   AGING CELL

The genetic component of human longevity: analysis of the survival advantage of parents and siblings of Italian nonagenarians

(2011) Alberto Montesanto et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A Genetic-Demographic Approach Reveals Male-Specific Association Between Survival and Tumor Necrosis Factor (A/G)-308 Polymorphism

(2011) M. Cardelli et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Further Support to the Uncoupling-to-Survive Theory: The Genetic Variation of Human UCP Genes Is Associated with Longevity

(2011) Giuseppina Rose et al.   PLoS One

Genetic variation in insulin/IGF-1 signaling pathways and longevity

(2010) Elad Ziv et al.   AGEING RESEARCH REVIEWS

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

(2009) Ludmila Pawlikowska et al.   AGING CELL

Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians

(2009) G. Atzmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of interleukin-6 polymorphisms on human longevity: A systematic review and meta-analysis

(2008) Danilo Di Bona et al.   AGEING RESEARCH REVIEWS