Sugar or Fat?—Metabolic Requirements for Immunity to Viral Infections
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Sugar or Fat?—Metabolic Requirements for Immunity to Viral Infections
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-10-16
DOI
10.3389/fimmu.2017.01311
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hyperactivation of mammalian target of rapamycin complex 1 by HIV-1 is necessary for virion production and latent viral reactivation
- (2017) Binod Kumar et al. FASEB JOURNAL
- Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection
- (2017) Clovis S. Palmer et al. FEBS LETTERS
- Rapamycin-mediated mTOR inhibition uncouples HIV-1 latency reversal from cytokine-associated toxicity
- (2017) Alyssa R. Martin et al. JOURNAL OF CLINICAL INVESTIGATION
- Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism
- (2017) Youdong Pan et al. NATURE
- Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B
- (2017) Paola Fisicaro et al. NATURE MEDICINE
- Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals
- (2017) Johanna Tauriainen et al. Scientific Reports
- Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation
- (2017) Lindsey Araujo et al. eLife
- CD4+ T cells with an activated and exhausted phenotype distinguish immunodeficiency during aviremic HIV-2 infection
- (2016) Marcus Buggert et al. AIDS
- Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming
- (2016) Michael D. Buck et al. CELL
- L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
- (2016) Roger Geiger et al. CELL
- The mTOR Complex Controls HIV Latency
- (2016) Emilie Besnard et al. Cell Host & Microbe
- Constitutive Glycolytic Metabolism Supports CD8 + T Cell Effector Memory Differentiation during Viral Infection
- (2016) Anthony T. Phan et al. IMMUNITY
- Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion
- (2016) Bertram Bengsch et al. IMMUNITY
- Emerging Role and Characterization of Immunometabolism: Relevance to HIV Pathogenesis, Serious Non-AIDS Events, and a Cure
- (2016) Clovis S. Palmer et al. JOURNAL OF IMMUNOLOGY
- Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiation
- (2016) Kristen N Pollizzi et al. NATURE IMMUNOLOGY
- Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy
- (2016) Mahima Swamy et al. NATURE IMMUNOLOGY
- Metabolic pathways in T cell activation and lineage differentiation
- (2016) Luís Almeida et al. SEMINARS IN IMMUNOLOGY
- Metabolic profiling during HIV-1 and HIV-2 infection of primary human monocyte-derived macrophages
- (2016) Joseph A. Hollenbaugh et al. VIROLOGY
- Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells
- (2016) Mulki Angela et al. Nature Communications
- Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner
- (2016) Lianjun Zhang et al. Cell Reports
- Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host
- (2016) Anna Schurich et al. Cell Reports
- TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection
- (2016) Glen M. Chew et al. PLoS Pathogens
- Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis
- (2016) Clovis S. Palmer et al. EBioMedicine
- Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions
- (2016) Gaspard Cretenet et al. Scientific Reports
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity
- (2015) Guoliang Cui et al. CELL
- Regulators of Glucose Metabolism in CD4+ and CD8+ T Cells
- (2015) Clovis S. Palmer et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Viremic and Virologically Suppressed HIV Infection Increases Age-Related Changes to Monocyte Activation Equivalent to 12 and 4 Years of Aging, Respectively
- (2015) Thomas A. Angelovich et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation
- (2015) Kristen N. Pollizzi et al. JOURNAL OF CLINICAL INVESTIGATION
- T cell metabolism drives immunity
- (2015) Michael D. Buck et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Glucose, glycolysis and lymphocyte responses
- (2015) Raymond P. Donnelly et al. MOLECULAR IMMUNOLOGY
- Combined Use of Metformin and Everolimus Is Synergistic in the Treatment of Breast Cancer Cells
- (2015) Yunshan Wang et al. ONCOLOGY RESEARCH
- Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice
- (2015) Alonso Heredia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation
- (2015) Dorota Klysz et al. Science Signaling
- Activation and Exhaustion of Adaptive Immune Cells in Hepatitis B Infection
- (2015) Dimpu Gogoi et al. VIRAL IMMUNOLOGY
- PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
- (2015) Nikolaos Patsoukis et al. Nature Communications
- Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation
- (2015) Dorota Klysz et al. Science Signaling
- 2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy
- (2014) Dongsheng Zhang et al. CANCER LETTERS
- The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function
- (2014) Andrew N. Macintyre et al. Cell Metabolism
- Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development
- (2014) David O’Sullivan et al. IMMUNITY
- Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways
- (2014) S. R. Jacobs et al. JOURNAL OF IMMUNOLOGY
- Regulator of Fatty Acid Metabolism, Acetyl Coenzyme A Carboxylase 1, Controls T Cell Immunity
- (2014) J. Lee et al. JOURNAL OF IMMUNOLOGY
- Glucose Transporter 1–Expressing Proinflammatory Monocytes Are Elevated in Combination Antiretroviral Therapy–Treated and Untreated HIV+Subjects
- (2014) Clovis S. Palmer et al. JOURNAL OF IMMUNOLOGY
- Metabolism of stromal and immune cells in health and disease
- (2014) Bart Ghesquière et al. NATURE
- Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs
- (2014) S. Shrestha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity
- (2014) S.-C. Cheng et al. SCIENCE
- CD160-Associated CD8 T-Cell Functional Impairment Is Independent of PD-1 Expression
- (2014) Selena Viganò et al. PLoS Pathogens
- The Many Unknowns Concerning the Bioenergetics of Exhaustion and Senescence during Chronic Viral Infection
- (2014) Anna Schurich et al. Frontiers in Immunology
- Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection
- (2013) Clovis S. Palmer et al. AIDS
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- AMPKα1: A glucose sensor that controls CD8 T-cell memory
- (2013) Julia Rolf et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Sprouty-2 regulates HIV-specific T cell polyfunctionality
- (2013) Yen-Ling Chiu et al. JOURNAL OF CLINICAL INVESTIGATION
- Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
- (2013) Gilad Doitsh et al. NATURE
- Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
- (2013) Linda V Sinclair et al. NATURE IMMUNOLOGY
- Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch
- (2013) Patrick M Gubser et al. NATURE IMMUNOLOGY
- CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability
- (2013) G. J. W. van der Windt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fueling Immunity: Insights into Metabolism and Lymphocyte Function
- (2013) E. L. Pearce et al. SCIENCE
- Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection
- (2012) L. Trautmann et al. BLOOD
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
- (2012) Alfredo Castello et al. CELL
- Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation
- (2012) Rajesh R. Rao et al. IMMUNITY
- PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+T cells
- (2012) David K. Finlay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes
- (2012) M. A. Paley et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Glut1-mediated glucose transport regulates HIV infection
- (2012) S. Loisel-Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
- (2011) Sophia Y. Lunt et al. Annual Review of Cell and Developmental Biology
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
- (2011) Gerritje J.W. van der Windt et al. IMMUNITY
- N-Acetylglucosamine Inhibits T-helper 1 (Th1)/T-helper 17 (Th17) Cell Responses and Treats Experimental Autoimmune Encephalomyelitis
- (2011) Ani Grigorian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
- (2011) Maria M. Mihaylova et al. NATURE CELL BIOLOGY
- Everolimus in Clinical Practice in Long-Term Liver Transplantation: An Observational Study
- (2011) T. Casanovas et al. TRANSPLANTATION PROCEEDINGS
- The mTOR Kinase Determines Effector versus Memory CD8 + T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin
- (2010) Rajesh R. Rao et al. IMMUNITY
- Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche
- (2010) A. Banerjee et al. JOURNAL OF IMMUNOLOGY
- Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies
- (2010) Mark Stein et al. PROSTATE
- Enhancing CD8 T-cell memory by modulating fatty acid metabolism
- (2009) Erika L. Pearce et al. NATURE
- mTOR regulates memory CD8 T-cell differentiation
- (2009) Koichi Araki et al. NATURE
- HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
- (2009) Nicolas Chomont et al. NATURE MEDICINE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
- (2008) Candace M. Cham et al. EUROPEAN JOURNAL OF IMMUNOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started